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<p>Please enquire for more information about Methyl 3-formyl-6-methoxy-1-(4-methoxybenzyl)-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

2-Chloro-1-methylquinolinium tetrafluoroborate (2CQBF) is a synthetic compound that inhibits protein synthesis. It has been used as an analytical reagent for the determination of proteins, including those in urine samples. 2CQBF has been shown to be effective in the treatment of cancer and other diseases, such as lupus erythematosus, arthritis, and psoriasis.

<p>8-Fluoroquinoline is a quinoline derivative that has been shown to have in vitro anticancer activity against colon adenocarcinoma cells. It is a chiral molecule that can exist as two stereoisomers, (R)-8-fluoroquinoline and (S)-8-fluoroquinoline. These isomers may have different interactions with the tumorigenic cells, but both of them have anticancer activity. 8-Fluoroquinoline also interacts with cytochrome P450 enzymes, enhancing their ability to metabolize carcinogens.</p>

<p>Bis(8-quinolinolato)zinc (II) is a molecule that contains carboxylate groups. It has been shown to be processable and can be used in fabrication processes. Bis(8-quinolinolato)zinc (II) also exhibits optical properties. The metal ion in the molecule is able to form complexes with other metals, which may affect transport properties, ionization mass and morphology of the compound. It can also be used for magnetic resonance spectroscopy studies, as well as plasma mass spectrometry.</p>

<p>Demethylsuberosin is a naturally-occurring compound, specifically a coumarin derivative, which is often extracted from plants. It originates from numerous botanical sources, including the family Rutaceae, where it serves as a secondary metabolite. Its mode of action involves the inhibition of fungal and bacterial growth, achieved by disrupting the integrity of microbial cell walls and interfering with their replication processes.</p>

Indole-3-carboxylic acid methyl ester is a quinoline derivative that is structurally related to the well-known antibiotic, ciprofloxacin. It has been shown to be cytotoxic against a variety of bacterial strains including Pseudomonas aeruginosa and Staphylococcus aureus. The mechanism of action for this compound is not yet fully understood, but it has been shown to inhibit collagen production in cell cultures and induce neuronal death in mice. Indole-3-carboxylic acid methyl ester also possesses anti-cancer properties and inhibits fatty acid synthesis. This compound also has antifungal effects against Candida albicans and other fungi.

<p>1-Methyl-5-nitro-1H-imidazole-2-methanol 2-carbamate is an antimicrobial agent that has been shown to be active against a number of bacteria, including Gram negative and Gram positive bacteria. It was shown to have a matrix effect in vivo and its kinetic energy was found to be reactive. The 1NIMC has been shown to inhibit the growth of bacteria by interfering with DNA replication and RNA synthesis. This drug has also been shown to have an analytical method that is linear in calibrations curves, which makes it suitable for quantitative analysis. It also has chemical stability, as it decomposes slowly at room temperature.</p>

5-Azaindole is a heterocyclic compound that has been studied for its biological properties. It is a prodrug of trifluoroacetic acid, which can be used to treat metabolic disorders and autoimmune diseases. 5-Azaindole has also been shown to increase the expression of growth factor in cells, which may be useful in treating pain or bowel disease. This drug is metabolized by hydroxylation followed by conjugation with glucuronic acid and excretion in the urine. 5-Azaindole is also converted to an active form by enzymatic oxidation of a hydroxyl group and protonation on the nitrogen atom, as well as conversion to sorafenib (a drug used to inhibit tumor growth).

<p>6-Nitroindole is a heterocyclic compound that belongs to the group of nitro compounds. It is a methylating agent that can be used for the production of 6-nitropurines, which are used as anticancer agents. The reaction mechanism of this compound involves the attack of the electrophilic nitro group on an electron-deficient carbon atom in a molecule. This process creates an N-methylated product, which can then be oxidized to form a carboxylic acid. The kinetics of this reaction have been studied using kinetic data and anomers. 6-Nitroindole has also been shown to inhibit DNA synthesis by binding to oligodeoxynucleotides and inhibiting their catalytic activity.</p>

<p>1-Acetyl-3-indolecarboxaldehyde is a ligand that binds to the cannabinoid receptor 1 (CB1). It has been shown to bind to the CB1 receptor with high affinity and selectivity. In addition, it has been demonstrated to inhibit the proliferation of human breast cancer cells in vitro. The compound is used as a fluorescent probe for cb1 receptor binding. Data obtained from molecular modelling studies have suggested that the hydroxyl group might be involved in binding to the CB1 receptor. 1-Acetyl-3-indolecarboxaldehyde also binds carotenoids, which are molecules responsible for giving plants and other photosynthetic organisms their coloration. This compound can be found in many different plants, such as carrots and bananas, where it acts as an antioxidant.</p>

Chelating agent used to detect aqueous copper ions by electrochemiluminescence

2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine is a fine chemical that belongs to the group of versatile building blocks. It can be used as a reagent or as a speciality chemical in research and development. 2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine is also a useful scaffold for the synthesis of complex compounds and has been shown to be an effective inhibitor of protein tyrosine kinases.

<p>Pyridoxine-5'-phosphate is a cofactor of the enzyme pyridoxal kinase, which catalyzes the conversion of pyridoxine to pyridoxal. Pyridoxine-5'-phosphate is also an essential cofactor for the enzyme transketolase, which catalyzes the transfer of a sugar phosphate group from erythrose 4-phosphate to dihydroxyacetone phosphate. Pyridoxine-5'-phosphate is involved in many reactions in the body, including protein synthesis and metabolism. It is required for glucocorticoid receptor activation and transcriptional regulation. It may also play a role in growth factor-β1 production and its role in cell signaling pathways. The deficiency of this vitamin causes symptoms such as weakness, irritability, depression, apathy, memory loss, hallucinations or convulsions.</p>

<p>4,6-Dichloroindole-2-carboxylic acid (DCI) is a potential drug candidate for the treatment of neurological disorders. DCI binds to glutamate receptors, which are involved in many neurological diseases. It has been shown to inhibit glutamate dehydrogenase and thus block the production of glutamate from glucose. DCI also prevents neuronal death caused by excessive levels of glutamate and inhibits the activation of N-methyl-D-aspartate (NMDA) receptors. This drug is currently being investigated as a therapy for inflammatory diseases such as multiple sclerosis and Alzheimer's disease. One study has shown that DCI may be useful for treating cerebellar granule cells in a model system. It has been found to inhibit glycogen synthase kinase 3, which is an enzyme involved in signaling pathways that regulate cell growth and survival.</p>

6-Amino-2-chloropurine (6AC) is a nucleoside analogue that inhibits the synthesis of DNA, RNA, and protein by inhibiting the activity of polymerase chain reaction. It has been used to study the molecular mechanisms of pandemic influenza A virus and HIV infection. 6AC has also been shown to be effective in treating solid tumours and metastatic colorectal cancer in mice. This drug is also used as a competitive inhibitor for measuring endonuclease activity in polymerase chain reactions. 6AC binds to the enzyme's active site and prevents it from cleaving the DNA strands during replication, resulting in incomplete replication of the viral genome.

<p>Clioquinol is a topical corticosteroid that is used to treat skin disorders such as pemphigoid, psoriasis, and eczema. It is also used to treat the inflammation associated with acne. Clioquinol has been shown to be effective in treating bacterial infections of the skin by inhibiting the growth of bacteria. This drug also has anti-inflammatory properties and can be used for the treatment of various inflammatory skin conditions. Clioquinol is not absorbed through the skin and does not affect the blood's ability to clot.</p>

1,3-Diacetylindole is an alkene that belongs to the class of organic compounds. It can be prepared by Friedel-Crafts acylation of cyclopentenone with formaldehyde and hydrogen chloride gas. The molecule has a molecular electrostatic potential of -0.8 eV and a molecular weight of 126.1 g/mol. 1,3-Diacetylindole has been shown to react with Grignard reagent in an electrochemical study. Additionally, it has been used as a starting material for the synthesis of other molecules such as 2-methylquinoline and 1,2-dihydroquinoline. The vibrational and spectral data for 1,3-diacetylindole have been obtained using both experimental and computational methods. These data are useful for understanding the structure and reactivity of this compound at the molecular level.br>br> br>br>

Methyl indole-4-carboxylate is a synthetic compound that is a potent agonist for cytochrome P450 enzymes. It can be used to study the human cytochrome system, which is responsible for metabolizing drugs and other chemicals. Methyl indole-4-carboxylate has been shown to react with aldehydes, such as formaldehyde, leading to fluorescence. This compound also has the ability to bind to x-ray structures of human cytochrome p450. The addition of methyl indole-4-carboxylate to tissue culture cells leads to an increase in activity of tuberculosis by inhibiting the growth of Mycobacterium tuberculosis and Mycobacterium avium complex.

7-Bromoindole is a synthetic compound that has been used as an analog for indole. It has been shown to have some biological activity in vivo, but it is not known if this activity is due to the drug itself or its breakdown products. 7-Bromoindole can be decarboxylated under acid conditions and saponified with sodium hydroxide. The isolated yield of this reaction is about 2 grams per mole of reactant. 7-Bromoindole shows hemolytic activity against human pathogens such as Staphylococcus aureus and Escherichia coli, but not against Bacillus subtilis or Pseudomonas aeruginosa.

(3-Formyl-1-indolyl)acetic acid is a small molecule that has been shown to inhibit the activity of various enzymes, including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and histamine N-methyltransferase (HNMT). The crystal structure of (3-formyl-1-indolyl)acetic acid was determined by X-ray crystallography. The active conformation of the molecule was found to be a nonplanar chair conformation with a hydrogen bond acceptor at C8. This conformation is stabilized by a hydrogen bond donor at C7, which also creates an additional hydrogen bond acceptor at O2. These interactions stabilize the molecule in its active form. The docking studies showed that the ligand binds to AChE with high affinity, while binding to BChE and HNMT with lower affinity. The inhibition effects on these

<p>Umbelliferone or 7-hydroxycoumarin is a widespread natural product of the coumarin family. It occurs in many familiar plants from the umbelliferae family. Umbelliferone can be used as a fluorescence indicator for metal ions such as copper and calcium. It acts as a pH indicator in the range 6.5-8.9.</p>

<p>4,4'-Dinonyl-2,2'-bipyridine is a high-yield transfer reagent that is used in organic synthesis. It can be used to transfer aryl or alkyl groups from ancillary to the functional group on the substrate. 4,4'-Dinonyl-2,2'-bipyridine is also used for the production of polymers and organic semiconductors. In addition, this compound has been shown to be useful in the production of silicon solar cells and as a catalyst for photovoltaic devices. 4,4'-Dinonyl-2,2'-bipyridine has been shown to be thermostable and can be used in temperatures up to 200°C. This compound is also a ligand with ruthenium complex properties and can be used as an electron acceptor in radiation therapy procedures.</p>

<p>N-Acetyl-3-hydroxyindole is a colorless liquid that inhibits the activity of enzymes such as butyric acid, active methylene, and acyl halides. It is also used to inhibit the enzyme eosinophil peroxidase in clinical tests. N-Acetyl-3-hydroxyindole has been shown to be an efficient method for high-throughput analysis of enzymatic reactions. This chemical can be immobilized on porous supports and used to measure enzyme activities. N-Acetyl-3-hydroxyindole has been shown to have therapeutic effects in clinical data with a potent inhibitor of eosinophil peroxidase.</p>

<p>2,2,4-Trimethyl-1,2,3,4-tetrahydroquinoline-8-carboxylic acid is a versatile building block that can be used as a reagent or speciality chemical in research and development. It is also an intermediate for the synthesis of complex compounds with various properties. This compound has been shown to be useful as a building block for the synthesis of new compounds with potential pharmaceutical applications.</p>

<p>Angelicin is a furanocoumarin compound, which is derived from various plant sources, particularly within the Apiaceae family. The source of angelicin is often linked to traditional medicinal plants, where it is extracted and subsequently isolated for scientific investigation. Angelicin's mode of action involves intercalating within DNA strands, thereby affecting transcription and replication processes. This action is understood to be primarily photoactivated, leading to the formation of covalent bonds with DNA upon exposure to ultraviolet light, which can result in cross-linking.</p>

Methyl indole-5-carboxylate is a hdac inhibitor that has been shown to have anticancer activity. It has been shown to inhibit the growth of hCT116 cells and xenograft tumors in mice. Methyl indole-5-carboxylate is also an active analog for other anticancer agents, such as 5-azacytidine and 5-aza-2'-deoxycytidine. The drug is cytotoxic to L6 cells and increases the expression of p21 protein, which inhibits tumor cell proliferation. This compound is metabolized by cytochrome P450 enzymes into methyl indole carboxylate, which can be further converted into a reactive intermediate that binds DNA.

<p>8-Geranyloxypsoralen is a natural furanocoumarin, which is a secondary metabolite typically derived from plants, particularly those in the Rutaceae family. Its source lies predominantly in certain fruits and herbs, where it functions as a natural defense compound.</p>

Fmoc-L-octahydroindole-2-carboxylic acid is a synthetic amino acid that is used in the synthesis of peptides and proteins. It has been shown to be an agonistic ligand for the acetylcholine receptor and may be used as an anti-inflammatory drug. Fmoc-L-octahydroindole-2-carboxylic acid is synthesized by combining piperidine and fmoc-glycine, followed by condensation with iminoacetic acid. The synthesis of this compound can be achieved through solid phase synthesis or chemical methods. The removal of the FMOC group requires acidic conditions such as trifluoroacetic acid or hydrochloric acid.

<p>1-(Bromoacetyl)indoline is a chemical compound that can be used as a reaction component, reagent, or high-quality research chemical. It is a speciality chemical used in the production of fine chemicals and other organic compounds. 1-(Bromoacetyl)indoline is a versatile building block for synthesis of complex compounds with potential applications in pharmaceuticals, agrochemicals, and specialty chemicals.</p>

<p>7-Hydroxycoumarin is a fluorescent compound, known as a coumarin derivative, which is a naturally occurring chemical found in many plants. Derived from the umbelliferone compound family, it exhibits strong blue fluorescence under UV light due to its unique structural properties. This fluorescence is a result of its molecular conjugation and the electron-donating nature of the hydroxyl group, allowing it to absorb and emit light efficiently.</p>

7-Benzyloxyindole is a regulatory compound that is used to study the interactions between transcription factors and chromatin. 7-Benzyloxyindole has been shown to induce caspase-independent cell death in human pathogens. 7-Benzyloxyindole induces reactive oxygen species and alters the expression of genes involved in the immune system and inflammation, suggesting an interaction with transcriptional regulation. 7-Benzyloxyindole's hemolytic activity may be due to its enantiomer, which binds to carotenoids such as β-carotene or retinol and forms a complex that is more reactive than the parent molecule. This reactive form of 7-benzyloxyindole has been shown to induce cell death in staphylococcus, suggesting a possible use for this drug as an antibacterial agent against opportunistic fungal infections.

8-Methoxy-2-methylquinolin-5-amine monohydrochloride is a fine chemical that is used as a versatile building block in the synthesis of complex compounds. 8-Methoxy-2-methylquinolin-5-amine monohydrochloride is an intermediate for the production of research chemicals and pharmaceuticals. It can be used to synthesize speciality chemicals, useful scaffolds, and reagents. It also has a wide range of applications as a reaction component in synthetic organic chemistry. 8-Methoxy-2-methylquinolin-5-amine monohydrochloride has high purity and quality.

<p>2-Chloroquinoline-8-carboxylic acid is a fine chemical that is useful as a scaffold for the synthesis of other compounds. It is a versatile building block and can be used in the production of the drug chloroquine. 2-Chloroquinoline-8-carboxylic acid has been used as an intermediate in research chemicals, reaction components in speciality chemical and complex compound. This compound has high quality and can be used as a reagent.</p>

<p>4-Chloroindole is an indole compound that is a derivative of salicylic acid. It is used in the production of ethylene and casein, as well as being a major metabolite of anthranilic acid. 4-Chloroindole is also found in environmental pollutants and has been shown to be active against plant pathogens such as Pseudomonas syringae. It has been shown to inhibit the growth of Bacillus cereus by binding to its ribosomal RNA and inhibiting protein synthesis. In addition, it inhibits the biosynthesis of methylindole, which may be due to its ability to inhibit the enzyme tryptophan synthase.</p>

6-Chloro-9-(tetrahydro-2H-pyran-2-yl)purine is a nucleoside analog that is used to treat various types of cancer. It is a c–h bond regiospecific nucleophile that forms the 6-chloro 9-(tetrahydro-2H-pyran-2-yl)purine intermediate. The chloride ion acts as a nucleophile in the first step of this process, which results in the formation of an organocuprate and glyoxylate. 6CPP binds to DNA and inhibits RNA synthesis, leading to cell death by apoptosis or necrosis. This drug has been shown to be effective for treating human cell lines. 6CPP is also known for its antitumor effects, which may be due to its ability to inhibit phosphonates and cross-coupling reactions.

6-Nitroindoline is a nitro compound that inhibits the polymerization of nitrite. It is an acidic acceptor and has been used as an agrochemical to inhibit nitrification in soil. 6-Nitroindoline has been shown to be mutagenic, which may be due to its ability to form covalent bonds with DNA bases or alkylate DNA bases. 6-Nitroindoline can also undergo borohydride reduction, which is the conversion of a compound into a more reduced form by reaction with borohydride.

<p>7-Chloroindole is a potent compound that inhibits bacterial growth. It has been shown to inhibit the growth of tumour cell lines at submicromolar concentrations, with an IC50 of 0.5 µM. 7-Chloroindole also strongly inhibits the growth of Staphylococcus aureus, with an IC50 of 0.1 µM. This compound does not cause cell death by caspase-independent pathways, but rather induces a dry weight increase and surface methodology changes in cells treated with this compound. 7-Chloroindole belongs to the class of compounds known as carotenoids and has been shown to have a neutral pH optimum. It is formed through an enzymatic reaction involving two molecules of malonyl-CoA and one molecule each of acetate and chlorophyllide a.</p>

Please enquire for more information about 6-Methoxyindole-3-acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>6,6'-Dimethyl-2,2'-bipyridine (DMBP) is a bidentate ligand that is used in the functional theory of antibacterial activity. The bond cleavage of DMBP is believed to be due to its high oxidation potential and its ability to form hydrogen bonds with the bacteria cell wall. DMBP has been shown to have an antibacterial effect on both Gram-positive and Gram-negative bacteria. The mechanism of action may be due to its ability to release hydroxyl radicals when exposed to ultraviolet light. This compound also has a boronic acid group that can form a complex with 4-methoxyphenylboronic acid (MPA) which can inhibit bacterial growth.</p>

<p>5-Bromoindole-2-carboxylic acid is an indole derivative that has been shown to inhibit the expression of MMP-13, a matrix metalloproteinase that is involved in tumor invasion and metastasis. This compound also inhibits the transcriptional activity of RNA polymerases I and II, which is important for preventing cancer cell proliferation. 5-Bromoindole-2-carboxylic acid may be used as a treatment for cancer by inhibiting collagen synthesis. This would reduce the size of a tumor by preventing it from expanding in size.</p>

<p>The optimal reaction conditions for the acylation of 5-bromoindole with 2,2,2-trichloroethyl chloroformate are a mixture of methanol and sodium hydroxide solution. Reaction products include 2-chloro-5-(trichloromethyl)quinoline and the quinoline derivative 1-(2,2,2-trichloroethyl)-1H-imidazole. UV absorption spectra of these products have been recorded in the range of 200 to 400 nm. The reaction is successfully monitored by following changes in the NMR spectrum. The liquid chromatography method is based on a reverse phase column and detection at 220 nm.</p>

<p>3-(9-((6-(2,5-Dioxopyrrolidin-1-yloxy)-6-oxohexyl)(tosyl)carbamoyl)acridinium-10-yl)propane-1-sulfonate is a fine chemical that is used as a versatile building block for complex compounds. It can be used in the synthesis of research chemicals or reagents, or as a speciality chemical. 3-(9-((6-(2,5-Dioxopyrrolidin-1-yloxy)-6-oxohexyl)(tosyl)carbamoyl)acridinium-10-yl)propane sulfonate can be reacted with other compounds to form useful scaffolds and reaction components. This compound has CAS number 866366–12–3.</p>

<p>5-Aminoisatin is a serotonin receptor agonist and has been shown to have protective effects against liver cancer in vitro in human liver cancer cells. It also has a number of other biological activities, including anti-inflammatory, natriuretic, and leukemia inhibitory activities. 5-Aminoisatin interacts with the mitochondrial membrane and prevents cell death by inhibiting the opening of the mitochondrial permeability transition pore (MPTP). This activity may be due to its ability to form ternary complexes with ATP and the voltage sensor domain of the mitochondrial protein voltage dependent anion channel (VDAC). 5-Aminoisatin binds to both the alpha subunit and beta subunit of the calcium/calmodulin-dependent protein kinase II (CaMKII) enzyme. The binding of 5-aminoisatin to CaMKII leads to inhibition of phosphorylation at serine residue 397, which disrupts ATP binding.</p>

5-Methoxyindole-2-carboxylic acid is a molecule that belongs to the class of diazonium salts. It is a potent inhibitor of mitochondrial membrane potential and has been shown to have anti-diabetic effects in animal models. 5-Methoxyindole-2-carboxylic acid also inhibits sperm motility, which may be due to its ability to inhibit uv absorption. This compound has been shown to be an effective agent in the treatment of brain infarctions when administered chronically orally. The mechanism of action is not known, but it may involve inhibition of potassium ion uptake or hydrogen bond formation with fatty acids.

<p>Metosulam is a triazolopyrimidine herbicide that inhibits the growth of weeds by interfering with plant photosynthesis. Metosulam binds to fatty acids and carbohydrates, which prevents these molecules from binding to the enzyme ATP synthase. This results in a loss of energy production, leading to cell death. Metosulam has been shown to cause chronic cough in mice when given at sublethal doses for long periods of time. The chronic cough was found to be due to an interactive effect between metosulam and polymeric matrix in the lungs that caused inflammation.</p>

<p>Scoparone is a bioactive natural compound, which is primarily derived from plants in the Rutaceae family, such as Artemisia species. It is a coumarin derivative, known for its therapeutic properties due to its diverse biological activities. The mode of action of scoparone is multifaceted, involving the modulation of various enzymes and signaling pathways. It acts as an inhibitor of cytochrome P450 enzymes and influences pathways involving nitric oxide and reactive oxygen species, contributing to its anti-inflammatory and hepatoprotective effects.</p>

<p>8-Hydroxyquinoline sulfate is a drug that has been used to study the cancer tissue response to various drugs. The 8-hydroxyl group in the molecule interacts with metals and forms chelate complexes, which may be the reason for its cytotoxic effect. 8-Hydroxyquinoline sulfate also inhibits mitochondrial membrane potential and blocks the receptor activity of some cell types. It has been shown to be significantly cytotoxic to HL-60 cells, as well as other cell lines.</p>

<p>6-Hydrazinopurine is an anti-hepatitis drug that is a prodrug for 6-chloropurine. Its mechanism of action is not fully understood, but it has been shown to bind to the virus receptor and inhibit the replication of the virus. It also competitively inhibits amines in biochemical assays. This property may be due to its hydroxyl group, which can form a hydrogen bond with the amino group of amines. It has been shown to be active against prostate carcinoma cells. 6-Hydrazinopurine has been shown to inhibit the growth of cancer cells by inducing apoptosis and decreasing cell proliferation.</p>

<p>9-Acetylphenanthrene is a pyridinium salt with triazolium and reduction products. The reduction products are formed by the reaction of the 9-acetylphenanthrene with chlorine atom or activated cyclic hydrocarbons. 9-Acetylphenanthrene has been shown to have glucocorticoid receptor affinity, which is due to its ability to bind to the hormone receptor in the cell membrane. This binding inhibits the interaction of cortisol with this receptor, preventing the activation of transcriptional responses that regulate gene expression. 9-Acetylphenanthrene also relaxes smooth muscle cells, which may be due to inhibition of calcium ion release from intracellular stores in response to acetylcholine.</p>

<p>Ethyl 5-methylindole-2-carboxylate is an antioxidant that is used as a reagent in the synthesis of other compounds. It has been shown to inhibit cancer cell growth in vitro via its ability to inhibit the metabolic activity of human hepatoma cells. Ethyl 5-methylindole-2-carboxylate has also been shown to have cytotoxic activity against human hepatoma cells in vitro, and may be a potential anticancer drug candidate.</p>