Composti policiclici

2-Aminoacridone is a fluorescent dye.  The applications of 2-Aminoacridone are extensive in biochemical and analytical research. It is commonly employed in glycoprotein and glycoconjugate studies, leveraging its high sensitivity and specificity in detecting saccharide structures. Researchers utilize this dye in various assays, including high-performance liquid chromatography (HPLC) and electrophoresis, to analyze carbohydrate content and structure. Its role is critical in advancing our understanding of carbohydrate-related biological processes, such as cell signaling and disease pathogenesis, facilitating developments in both diagnostics and therapeutic strategies.

Bathophenanthroline is a fluorescent probe that is used to detect the change in mitochondrial membrane potential. It is also able to measure the concentration of an element in a solution and can be used as a fluorescence probe for electron transfer reactions. Bathophenanthroline has been shown to have high sensitivity, which is attributed to its ability to form hydrogen bonding interactions with other molecules. Bathophenanthroline is an efficient adsorption agent, which can be used in the Langmuir adsorption isotherm technique. This chemical has been used as a fluorescence probe for chronic viral hepatitis and detection of methanol in plasma mass spectrometry.

4,4'-Dipyridyl is a cyclic peptide with a basic structure. It has been found to have inhibitory effects against the growth of bacteria in human serum and group P2. The x-ray crystal structures reveal that it has strong intermolecular hydrogen bonding interactions. Experimental solubility data and coordination models show that 4,4'-dipyridyl is soluble in anhydrous sodium. Structural analysis and kinetic energy calculations indicate that the inhibitor binding site is located on the hydroxyl groups of the backbone of the molecule. This ligand also binds to metal ions such as copper or zinc.

Applications 2-Acetamido-6-chloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 137896-02-7) is a compound useful in organic synthesis.
References Matsuda, A., et al.: J. Med. Chem., 35, 241 (1992),

Applications Indoline metabolite
References Lacroix, I., et al.: Nat. Prod. Lett., 7, 15 (1995), Yamada, Y., et al.: Chem. Pharm. Bull., 54, 788 (2006), Whitehead, T., et al.: App. Environ. Microbiol., 74, 1950 (2008),

Applications 1-Benzyl-5-bromoindole

Stability Store in freezer at -20°C
Applications 5-Amino-6-(methylamino)quinoline (cas# 14204-98-9) is a compound useful in organic synthesis.

Applications 1,1,2-Trimethyl-1H-benzo[e]indole-d6 is a labelled analogue of 1,1,2-Trimethyl-1H-benzo[e]indole (T896032). It is a useful research chemical.

Applications Used for synthesis of Rho kinase inhibitors.
References Biggadike, K., et al.: J. Med. Chem., 50, 6519 (2007), Cheng, Y., et al.: Bioorg. Med. Chem., 16, 4617 (2008),

Applications Quinoline derivative used in the preparation of compounds with anticonvulsant activity as well as compounds with potent antibacterial activity against gram-positive pathogens.
References Guo, L. et al.: Eur. J. Med. Chem., 44, 954 (2009); Jarvest, R.L. et al.: J. Med. Chem., 45, 1959 (2002);

Applications 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic Acid 1,1-Dimethylethyl Ester (cas# 123387-51-9) is a compound useful in organic synthesis.

Applications 2-(2-Chloroethyl-d4)-1H-isoindole-1,3-dione (cas# 1252995-10-0) is a compound useful in organic synthesis.

Applications 3-acetylindole (cas# 703-80-0) is a useful research chemical.

Stability Light Sensitive
Applications 2-Chloroindole is used to prepare 2-pyrrolidinone derivatives as anticonvulsants.
References Kenda, B., et al.: PCT Int. Appl. (2006), WO 2006128692 A2 20061207

Applications 6-Chloropurine, Hydrochloride (cas# 88166-54-5 ) is a compound useful in organic synthesis.

Applications 6-Chloro-7-deazapurine Hydrochloride (cas# 1243346-92-0) is a compound useful in organic synthesis.

Applications Methyl 1-(Cyclohexylmethyl)-1H-indazole-3-carboxylate is an intermediate in the synthesis of MDMB-CHMINACA (M203515), a synthetic cannabinoid with potential neurochemical effects at the CB1 receptor.
References Banister, S. ET AL.: ACS Chem. Neurosci., 7, 1241 (2016);

Applications 1,2-Diazabicyclo[2.2.2]octan-3-one is an intermediate used in the synthesis of Bicyclo Risperidone (B382800), which is an impurity of Risperidone (R525000); a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988); Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990); Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)

Applications 3-Bromoquinoline (cas# 5332-24-1) is a compound useful in organic synthesis.

Applications 7-(4-(4-Chlorobutoxy)butoxy)-3,4-dihydroquinolin-2(1H)-one is an internmediate in the synthesis of Aripiprazole (A771000) related compounds, a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.
References Nagasaka, Y., et al.: Biopharma. Drug. Dispo., 33, 304 (2012); Chen, X., et al.: J. Med. Chem., 55, 7141 (2012);