Composti policiclici

Applications 6-Chloro-7-deazapurine Hydrochloride (cas# 1243346-92-0) is a compound useful in organic synthesis.

Stability Store in freezer at -20°C
Applications 5-Amino-6-(methylamino)quinoline (cas# 14204-98-9) is a compound useful in organic synthesis.

Applications 1,1,2-Trimethyl-1H-benzo[e]indole-d6 is a labelled analogue of 1,1,2-Trimethyl-1H-benzo[e]indole (T896032). It is a useful research chemical.

Stability Light Sensitive
Applications 2-Chloroindole is used to prepare 2-pyrrolidinone derivatives as anticonvulsants.
References Kenda, B., et al.: PCT Int. Appl. (2006), WO 2006128692 A2 20061207

Applications 5-Nitroisoquinoline (cas# 607-32-9) is a compound useful in organic synthesis.

Applications 5-Hydrazino-2(1H)-quinolinone Hydrochloride is an intermediate used in the synthesis of sodium-hydrogen exchanger type 1 inhibitor (NHE-1).

Applications 6-Chloro-4-(2-cyclopropylethynyl)-3,4-dihydro-3-(phenylsulfonyl)-4-(trifluoromethyl)-2(1H)-quinolinone is an intermediate in the synthesis of novel quinolinones as HIV-1 reverse transcriptase inhibitors.
References Patel, M., et al.: Bioorg. Med. Chem. Lett., 11, 1943 (2001);

Applications 3-acetylindole (cas# 703-80-0) is a useful research chemical.

Applications 2-[(Diethylamino)methyl]indole Methiodide is an intermediate in the preparation of carcinogenic indole derivatives.
References Eenkhoom, J.A., et al.: CND. J. Chem., 51, 792 (1973);

Applications A labelled intermediate of Irbesartan (I751000).
References Gillis, J., et al.: Drugs, 54, 885 (1997), Chando, T., et al.: Drug Metab. Disps., 26, 408 (1998), Hines, J., et al.: Eur. J. Pharmacol., 384, 81 (1999)

Applications Used in the synthesis of tetrahydroisoquinoline derivatives.

Applications Indole derivative

Applications 1,3-Dihydro-N-nitro-1,3-dioxo-2H-isoindole-2-carboximidothioic acid Methyl Ester-13C is an intermediate used in the synthesis of Clothianidin-d3,13C1 (C588502), which is the isotope labelled analog of Clothianidin. Clothianidin is a neonicotinoid insecticide for use in food crops.
References Kamel, A., et al.: J. Agric. Food Chem., 58, 5926 (2010), Lynd, L., et al.: Energy Environ. Sci., 3, 1150 (2010), Cresswell, J., et al.: Ecotoxicology, 20, 149 (2011),

Applications Quinoline derivative used in the preparation of compounds with anticonvulsant activity as well as compounds with potent antibacterial activity against gram-positive pathogens.
References Guo, L. et al.: Eur. J. Med. Chem., 44, 954 (2009); Jarvest, R.L. et al.: J. Med. Chem., 45, 1959 (2002);

Applications 2-Chloro-5-nitroquinoline is used in the synthesis of potent, orally active corticotropin-releasing factor-1 receptor antagonists.
References Takeda, K., et al.: BIoorg. Med. Chem., 20, 6559 (2012); Verheij, M.H.P., et al.: J. Med. Chem., 55, 8603 (2012); Takeda, K., et al.: Bioorg. Med. Chem. Lett., 22, 5372 (2012);

Applications 3-Bromoquinoline (cas# 5332-24-1) is a compound useful in organic synthesis.

Applications 7-(4-(4-Chlorobutoxy)butoxy)-3,4-dihydroquinolin-2(1H)-one is an internmediate in the synthesis of Aripiprazole (A771000) related compounds, a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.
References Nagasaka, Y., et al.: Biopharma. Drug. Dispo., 33, 304 (2012); Chen, X., et al.: J. Med. Chem., 55, 7141 (2012);

Applications Used in the synthesis of tetrahydroisoquinoline derivatives.

Applications A reagent used in the preparation of biologically active Azaindoles.
References Minakata, S., et al.: J. Agric. Food Chem., 45, 2345 (1997),

Applications 6-Chloro-3-(phenylsulfonyl)-4-(trifluoromethyl)-2(1H)-quinolinone is an intermediate in the synthesis of novel quinolinones as HIV-1 reverse transcriptase inhibitors.
References Patel, M., et al.: Bioorg. Med. Chem. Lett., 11, 1943 (2001);