
Leganti organometallici
Sottocategorie di "Leganti organometallici"
- Leganti di Buchwald(22 prodotti)
- DPEN(4 prodotti)
- DPHEN(4 prodotti)
- JOSIPHOS(4 prodotti)
- Fosfina(497 prodotti)
- Porfirina(75 prodotti)
Trovati 2889 prodotti di "Leganti organometallici"
Zotepine
CAS:Prodotto controllatoAntagonist of dopamine (D2), serotonin (5-HT2A) and histamine H1 receptorsFormula:C18H18ClNOSPurezza:Min. 95%Colore e forma:PowderPeso molecolare:331.86 g/molRN 486
CAS:Bruton's tyrosine kinase antagonist; reduces Fcγ receptor signaling
Formula:C35H35FN6O3Purezza:Min. 95%Peso molecolare:606.69 g/molNilotinib HCl monohydrate - Bio-X ™
CAS:Nilotinib is a kinase inhibitor that is used for the treatment of Chronic Myeloid Leukemia (CML). This drug is also used for the treatment of CML that is resistant to imatinib. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. It also inhibits PDGFR and c-kit.
Formula:C28H22F3N7O•HCl•H2OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:583.99 g/molIsradipine
CAS:L-type calcium channel blockerFormula:C19H21N3O5Purezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:371.39 g/molFG 7142
CAS:Partial inverse agonist of benzodiazepine sites of the GABAA receptors with anxiogenic properties. FG 7142 is a pharmacological stressor which generates anxiety in humans and in experimental animals such as rhesus monkeys and rodents. FG 7142 also reduces food intake and frequency of feeding in male and female rats.Formula:C13H11N3OPurezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:225.25 g/molCamostat mesylate - Bio-X ™
CAS:Camostat is a serine protease inhibitor that is used for the treatment of chronic pancreatitis. This drug has shown to reduce inflammation and pain. Studies have shown that Camostat has also inhibited the entry of SARS-CoV-2 in lung cells by inhibiting the priming process of S-protein, necessary for the viral entry into host cells.Formula:C20H22N4O5•CH4O3SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:494.52 g/molAzumolene
CAS:Azumolene is a muscle relaxant drug, which is a synthetic derivative of dantrolene originating from hydantoin. The mode of action of Azumolene involves the inhibition of calcium ion release from the sarcoplasmic reticulum of skeletal muscle fibers. By impeding this release, Azumolene effectively reduces muscle contraction, thereby acting as a potent muscle relaxant.Formula:C13H9BrN4O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:349.14 g/molMCC 950 sodium
CAS:Inhibitor of NLRP3 inflammasome and suppressor of the inflammatory cytokine IL-1β secretion. The compound was tested in diabetic mice and was shown to decrease the incidence of cardiac arrythmias, which are common secondary complications in diabetes mellitus. MCC 950 has potential to reverse diabetes-induced pathologies in cardiac electrophysiology.Formula:C20H23N2O5S·NaPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:426.46 g/molLY 411575
CAS:Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 of 0.078 nM in vitro as well as decreased levels of Aβ40 and Aβ42 amyloids in brain of a mouse model for Alzheimer’s disease. In vitro studies confirmed that LY 411575 inhibited cleavage of Notch receptor at S3 site with IC50 of 0.39 nM, which blocked Notch activation and downstream signalling, leading to apoptosis in primary and immortalized Kaposi's sarcoma cells.Formula:C26H23F2N3O4Purezza:Min. 95%Colore e forma:SolidPeso molecolare:479.48 g/molMelitracen hydrochloride
CAS:Tricyclic antidepressantFormula:C21H26NClPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:327.89 g/molPonalrestat
CAS:Ponalrestat is an aldose reductase inhibitor, which is a synthetic compound developed for pharmacological purposes. It originates from chemical synthesis designed to target and inhibit the enzyme aldose reductase effectively. The mode of action involves the competitive inhibition of aldose reductase, an enzyme involved in the polyol pathway of glucose metabolism. By preventing the reduction of glucose to sorbitol, it reduces sorbitol accumulation associated with diabetic complications.Formula:C17H12BrFN2O3Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:391.19 g/molToceranib phosphate - Bio-X ™
CAS:Prodotto controllatoToceranib phosphate is a receptor tyrosine kinase inhibitor. Toceranib phosphate has been shown to be effective in the treatment of skin cancer and other types of cancer, including lung cancer and breast cancer. It is approved in the US as a treatment for canine mastocytoma (mast cell tumours).Formula:C22H25FN4O2·H3O4PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:494.45 g/molDilevalol hydrochloride
CAS:Prodotto controllatoBeta-adrenoceptor antagonist; anti-hypertensiveFormula:C19H24N2O3·HClPurezza:Min. 95%Colore e forma:SolidPeso molecolare:364.87UNC 4203
CAS:Potent and specific inhibitor of the tyrosine protein kinase Mer precursor (MERTK) with 38-fold selectivity over the FMS-like protein kinase FLT3. UNC 4203 inhibits MERTK with an IC50 value of 2.4 nM and shows favourable pharmacokinetic properties. In vivo experiments in mice showed that UNC 4203 dramatically decreased the phosphorylation of MERTK in bone marrow leukemia cells.Formula:C30H44N6OPurezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:504.71 g/molIndomethacin - Bio-X ™
CAS:Indomethacin is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin PGE2. It is used to treat pain, fever, and inflammation. Indomethacin's mechanism of action is not well understood, but it may be due to interference with the ability of PMNs to bind to the surface of bacteria or to release reactive oxygen species. The drug has been shown to reduce mitochondrial membrane potential in mammalian cells, leading to apoptosis. This effect on mitochondria may also contribute to Indomethacin's anti-inflammatory effects. Indomethacin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C19H16ClNO4Purezza:(%) Min. 95%Colore e forma:PowderPeso molecolare:357.79 g/mol(R)-ADX 47273
CAS:Positive allosteric modulator of the metabotropic glutamate receptor mGluR5 with EC50 in submicromolar range. The compound is able to increase mGluR5 function in vitro and in vivo. A study showed that ADX-47273 enhanced fear extinction learning as well as improved reversal learning in experimental animals.
Formula:C20H17F2N3O2Purezza:Min. 95%Colore e forma:SolidPeso molecolare:369.36 g/molValiglurax
CAS:Potent and selective positive allosteric modulator (PAM) of metabotropic glutamate receptor mGlu4. Valiglurax is orally bioavailable and CNS-penetrant mGlu4 PAM in preclinical development for the Parkinson’s disease therapy and alleviation of the motor symptoms.Formula:C16H10F3N5Purezza:Min. 95%Colore e forma:SolidPeso molecolare:329.28 g/molS26131
CAS:S26131 is an advanced glycation end product (AGE) inhibitor, which is a synthetic compound designed for laboratory research purposes. It is derived from chemical synthesis processes, offering a robust tool for investigating the biochemical pathways associated with glycation. Its mechanism of action involves the inhibition of AGE formation, which is a post-translational modification resulting from the non-enzymatic reaction between sugars and proteins or lipids. This biochemical modulation is vital for studying the implications of glycation in various physiological and pathological contexts.
Formula:C31H34N2O4Purezza:Min. 95%Peso molecolare:498.6 g/molCYT 387
CAS:Inhibits JAK1 and JAK2 kinasesFormula:C23H22N6O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:414.46 g/mol

