Composti organici chirali

Applications Apicidin is a potent (nM) cell permeable inhibitor of histone deacetylase. Also, Apicidin exhibits …

Applications Duloxetine Maleate is a dual serotonin and norepinephrine reuptake inhibitor (SNRI) and is used …

Applications AM580 is a retinoic acid receptor agonist. It inhibits the proliferation of various tumor …

Applications An optically active inhibitor. References Matsumura, S., et al.: Cancer Res. Clin. Oncol., 130, …

Applications Boc-Lys(Me)2-OH Hydrate is a compound useful in organic synthesis.

Applications N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-methylmethanesulfonamide is an impurity of the HMG-CoA reductase inhibitor Rosuvastatin (R700500).

Applications 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine is an impurity of pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase. Antilipemic. …

Applications O-Methyl 15-Oxo 17-Hydro Gibberellin A3 Diacetate is an intermediate in synthesizing 15β-OH Gibberellin A3 …

Applications Used in the preparation of Boceprevir (B674500) and its analogs.

Applications (S)-(+)-3-Aminopiperidine Dihydrochloride (cas# 334618-07-4) is a compound useful in organic synthesis. References Ishikawa, M., …

Applications N-[(1R,2R)-1,2,3,4-Tetrahydro-1-hydroxy-7-methoxy-2-naphthalenyl]chloroacetamide (cas# 153153-59-4) is a compound useful in organic synthesis. References Dijkstra, D., et …

Applications Reagent used for asymmetric syntheses. References Schlessinger, R., et al.: J. Org. Chem., 28, …

Applications An amino chiral derivative of Camphor. References Peng, R., et al.: Biochem. Pharmacol., 35, …

Applications Intermediate in the production of Ramelteon.

Applications (R)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N,N-dimethylmethanamine is an intermediate in the synthesis of ent-Ivabradine Hydrochloride (I940505), which is the …

Applications A HMG-COA reductase inhibitor; useful as anticholesteramic.

Applications Methyl 4-(Hydroxymethyl)cyclohexanecarboxylate is a useful reagent in the synthesis and biopharmaceutical evaluation of imatinib …

Applications N-[(6R)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-methylmethanesulfonamide is an impurity of the HMG-CoA reductase inhibitor Rosuvastatin (R700500).

Applications A IMP-1 metallo-β-lactamase inhibitor. References Greenlee, M.L., et al.: Boorg. Med. Chem. Lett., 9, …

Applications 2-[Bis(phenylmethyl)amino]-1-(3,4-dimethoxyphenyl)-ethanone is an intermediate in synthesizing (+)-Noradrenaline-d6 Bitartrate (N661027) which is a labeled analogue …

Applications 5β-Pregnane-3α,11,17α,20α-tetrol is an urine steroid used as a biomarker for detecting malignancy in adrenal …

Applications (S)-3-Boc-Amino-butylamine Hydrochloride, is used to prepare macrocyclic Hsp90 inhibitors as metabolically stabile potential antitumor …

Applications 6-Bromo Norgestrel is an intermediate in the synthesis of Norgestrel (N689500) impurities.

Applications Intermediate in the preparation of Lubiprostone.

Applications 18-O-Allyl Vinorelbine is an intermediate used in the synthesis of 18-O-Desmethyl Vinorelbine (D296550), which …

Applications 10-Deacetylbaccatin III (D198250) derivative.

Applications N-Boc (R,S)-Nornicotine (cas# 1076199-53-5) is a compound useful in organic synthesis.

Applications (S)-α-Methyl Benzenemethanamine (R)-Ethyl Methyl(phenylmethoxy)propanedioate is an intermediate in the asymmetric synthesis of (R)-(-)-chlozolinate through …

Applications 2-Methyl-4-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-2-ol is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a …

Applications Used in the preparation of labeled cocaine analogs. References Carroll, F.I., et al.: J. …

Applications The S enantiomer of binaphthol derivative as chiral quenching agent. References Strambini, G., et …

Applications Dechloro Lorcaserin is an impurity of Lorcaserin (L469890), a novel selective 5-HT2C-receptor agonist for …

Applications Synthetic triterpenoids, such as RTA 408, are antioxidant inflammation modulator (AIM) that can inhibit …

Applications Ristomycin Monosulfate is used in biological studies for ligand discovery of fluorescent HIV-1 Dimerization …

Applications N-[(1S,2S)-2-Methyl-1-[[[2-(4-morpholinyl)ethyl]amino]carbonyl]butyl]carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of peptideamides for treatment …

Applications Forskolin Hemisuccinate is a derivative fo Forskolin (F701800), a diterpene isolated from Coleus forskohlii, …

Applications A competitive inhibitor of porcine kidney prolidase. References King, G. et al.: Eur. J. …

Applications Diboc Biotin Methyl Ester is an intermediate in synthesizing 9-Methyl Biotin (M294075), which is …

Applications (4S,5S)-Methyl 2,2,5-Trimethyl-4-(prop-1-en-2-yl)-1,3-dioxolane-4-carboxylate is an impurity in the synthesis of (+)-Echimidine N-Oxide, which is a …

Applications An intermediate in partial synthesis of major human metabolites of Docetaxel (D494420), an antineoplastic. …

Applications O-Ethyl-D-norvaline is used as an intermediate in the synthesis of Perindopril (P287500), an angiotensin-converting …

Applications A metabolite of Vinorelbine (V315000). References Elmarakby, S., et al.: J. Med. Chem., 32, …

Applications rac-Nornicotine is a metabolite of rac-Nicotine (N412420). References Hecht, S., et al.: Carcinogenesis, 9, …

Applications An intermediate in partial synthesis of major human metabolites of Docetaxel (D494420), an antineoplastic. …

Applications Fmoc-tyr(2-cltrt)-oh

Applications A reagent for the synthesis of optically pure α-amino-acids.

Applications (3S,4S,5R)-5-(Acetyloxy)-3,4-dihydroxy-1-cyclohexene-1-carboxylic Acid Ethyl Ester is an intermediate in the synthesis of Shikimate-3-phosphate (S357026), an …

Applications D-Valine methyl ester hydrochloride is a protected form of D-Valine (V094200). D-Valine (an isomer …

Applications Histidine derivative. References Dahl, K., et al.: Bioorg. Chem., 10, 329 (1981),

Applications 7-O-2,2-Dichloroethoxycarbonyl Docetaxel is a metabolite of Docetaxel (D494420); an antineoplastic and antimitotic agent that …

Applications An intermediate in the synthesis of Ritonavir. References Kempf, D., et al.: J. Med. …

Applications N-(9-Fluorenylmethoxycarbonyl)-L-serine Phenacyl Ester is used in preparation of protected Serine.Also, used in preparation of …

Applications Larazotide Acetate is a selective α3β4* neuronal nicotinic ACh receptor antagonist. References Muldoon, P.P., …

Applications 3-Azido-1,4-dideoxy-1,4-dihydro-1,4-dioxorifamycin is a derivative of Rifamycin (R508200), an antibacterial agent.

Applications (3aα,4β,7aα)-3a,4,7,7a-Tetrahydro-4-hydroxy-1H-isoindole-1,3(2H)-dione is a metabolite of Captan (C175725), a fungicide, often added to pesticide mixtures …

Applications Deserpidine, is an antihypertensive drug related to Reserpine (R144600). It is naturally found in …

Applications L-β-Chloroalanine Methyl Ester Hydrochloride (cas# 17136-54-8) is a compound useful in organic synthesis.

Applications N-[(7S)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester is an intermediate in the synthesis of (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one, a building …

Applications 9-((1S,3R,4S)-4-Hydroxy-3-(((4-methoxyphenyl)diphenylmethoxy)methyl)-2-methylenecyclopentyl)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-1H-purin-6(9H)-one is a Monomethoxytrityl protected intermediate of 4’-epi-Entecavir (E558930), an epimeric impurity of the …

Applications Methyl-D-erythritol Phosphate Disodium Salt (M304650) derivative.

Applications Mupirocin (M794000) analog.

Applications δ-2-Cefodizime is a third generation of cephalosporin with a broad spectrum of antibacterial activity. …