Tossicologia

Applications Testosterone-2,2,4,6,6-d5 Acetate is a useful isotopically labeled compound of Testosterone 17-O-Acetate (T155025)

Applications Cyclohexanecarbonyl-d11 Chloride is labelled Cyclohexanecarbonyl Chloride which is used to prepare 1,2,3-triazoles as inhibitors of human immunodeficiency virus type 1 protease. It was also used to synthesize benzothiazole as potent antitumor agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Whiting, M., et al.: J. Med. Chem., 49, 7697 (2006); Yoshida, M., et al.: Bioorg. Med. Chem. Lett., 15, 3328 (2005)

Applications Chloramphenicol-3-O-sulfate Sodium Salt is a salt version of Chloramphenicol-3-O-sulfate (CAS 116512-90-4) which can be used in study for evidence for new metabolic pathways of Chloramphenicol in the duck. Metabolite of the drug Chloramphenicol (C325030).
References Cravedi, J. P., et al.: Drug Metab Dispos, 22, 578 (1994)

Applications Antiviral agent. Used for the treatment of severe acute respiratory syndrome (SARS).
References Weber, G., et al.: Cancer Res., 43, 3466 (1983), Broet, P., et al.: J. Clin. Oncol., 19, 2778 (2001), Galmarini, C., et al.: Leukemia, 15, 875 (2001), Barth, R., et al.: Cancer Res., 64, 6287 (2004), Song, M., et al.: Bioorg. Med. Chem., 12, 489 (2004),

Applications Fenbendazole-Amine Sulfoxide is a highly effective inhibitor of the helminth-specific enzyme, fumarate reductas in Ascaris suum. Also, it inhibits the polymerization of tubulin into microtubules in vitro.
References Barrowman, M. M., et al.: Biosci. Rep., 4, 879-883 (1984); Barrowman, M. M., et al.: Biochem. Pharmacol., 33, 3037-3040 (1984);

Applications 2-Fluoroimidazole is a chemical reagent used in the synthesis of cephalosporins.
References Jung, F. et al.: J. Antibio., 46, 992 (1993);

Applications 4-Chlorophenyl Benzoate is used as a reagent in the synthesis of phenstatin analogs via Fries rearrangement and Friedel-Crafts reaction. These biaryl analogs are antitubulin compounds.
References Tozatti, C., et al.: Quim. Nova, 35, 1758 (2012)