Eterocicli con azoto (N)

<p>Applications 4-amino-1,2,4-triazolidine-3,5-dione (cas# 21531-96-4) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 2-Fluoro-6-(trifluoromethyl)pyridine-3-boronic acid<br></p>

<p>Applications 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine Dihydrochloride is a useful reagent for synthesis of the bicyclic secondary amines via dimethylaminomethylene derivatives of 3-pyrrolidone and 3-piperidone.<br>References Fukui, H., et al.: Heterocycles, 56, 257 (2002);<br></p>

<p>Applications PIPERONYL ACETONE (cas# 55418-52-5) is a useful research chemical.<br></p>

<p>Applications 1-(pyridin-4-yl)-1H-pyrazole-3-carboxylic acid (cas# 911463-81-5) is a useful research chemical.<br></p>

<p>Applications Methyl 3-(2-Pyrrolyl)propanoate (cas# 69917-80-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Hydroxymethyl)pyridine N-Oxide (cas# 10242-36-1) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive, Air Sensitive<br>Applications pyrimidine-2-sulfonyl fluoride (cas# 35762-87-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2,4-Dichloro-5-trifluoromethylpyrimidine is a reactant in the preparation of pyrimidine derivatives as inhibitors of gene ALK protein Kinase phosphorylating kinase and as cell proliferation inhibitors.<br>References Yang, E.H., et. al.: Bull. Korean Chem. Soc., 34, 3129 (2013)<br></p>

<p>Applications 2-Amino-3-bromopyrazine-5-carboxylic Acid (cas# 887352-34-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Reagent used to prepare biosynthetic polymer surfactants designed for shear-stable endothelialization.<br>References Schaefer, A., et al.: J. Bacteriol., 178, 2897 (1996), Ruegsegger, M., et al.: J. Biomed. Mat. Res., 56, 159 (2001), Abdu-Allah, H., et al.: J. Med. Chem., 51, 6665 (2008), Georgiades, S., et al.: Bioorg. Med. Chem. Lett., 18, 3117 (2008),<br></p>

<p>Applications 5-Methyl-pyrazine-2-carboxylic Acid (cas# 5521-55-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-hydroxy-1H,2H-pyrrolo[1,2-d][1,2,4]triazin-1-one (cas# 50269-88-0) is a useful research chemical.<br></p>

<p>Applications 1,3-Bis[2,6-bis(1-methylethyl)phenyl]-2-carboxy-1H-imidazolium Inner Salt is synthesized from 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride(B426650). 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride is used as a reagent in the synthesis of NHC Copper(I) complexes bearing dipyridylamine ligands which exhibit interesting luminescent properties and are potential candidates for organic light-emitting diode applications. 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride is also used as a reagent in the synthesis of 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic Acid Methyl Ester (D476595); the methyl ester derivative of the drug Vadimezan (V084950).<br>References Marion, R., et al.: Inorg. Chem., 53, 9181 (2014); Buchanan, C.M., et al.: Clin. Sci., 122, 449 (2012); Fruh, M., et al.: Clin. Lung. Cancer., 14, 34 (2013)<br></p>

<p>Applications 4-Amino-2-chloro-3-methylbenzonitrile is a reagent used in synthesis of imidazolin-2-ones, which is designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs).<br>References Li, J. J., et al.: J. Med. Chem., 50, 3015-3025 (2007)<br></p>

<p>Applications 5-Bromo-2-cyano-3-(trifluoromethyl)pyridine<br></p>

<p>Applications 2-Chloro-6-ethyl-N,N-dimethylthieno[2,3-d]pyrimidin-4-amine-d6 is the isotope labelled analog of 2-Chloro-6-ethyl-N,N-dimethylthieno[2,3-d]pyrimidin-4-amine (C367635); a useful synthetic intermediate.<br></p>

<p>Applications imidazo[1,2-a]pyrimidin-2-ylmethanamine is a reagent used in the preparation of secondary and tertiary aminofurazans by nucleophilic substitution of nitrofurazans with primary and secondary amines.<br>References Sheremetev, A. B., et al.: Russ. Chem. Bull., 53, 596 (2004)<br></p>

<p>Applications 3-Hydroxymethyl-(1-oxy-2,2,5,5-tetramethylpyrroline)-15N is an isotope labelled spin-labelling compound.<br></p>

<p>Applications 2,4-DIHYDRO-[1,2,4]TRIAZOLE-3-THIONE (cas# 3179-31-5) is a useful research chemical.<br></p>

<p>Applications 1-Benzo[b]thien-4-yl-piperazine is the starting material to prepare piperazine-substituted benzothiophenes useful in treatment and prevention of mental disorders including CNS disorders.<br>References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006)<br></p>

<p>Applications 1-(Oxazol-2-yl)ethanone is a benzimidazole derivatives which is used as regulators of steroid receptor coactivators<br>References O'Malley, Bert W. et al.,PCT Int. Appl. (2017);<br></p>

<p>Applications L-threo-α-Phenyl-2-piperidineacetamide-d10 is an labelled intermediate in the synthesis of labelled L-threo-Ritalinic Acid (R533132).<br>References Chavan, A.B. et al.: Otg. Proc. Res. Dev., 14, 1473 (2010);<br></p>

<p>Applications A benzimidazole derivative that exhibits corrosion inhibiting properties against strong acids.<br>References Popova, A., Bull. Electrochem., 23, 137 (2007), Popova, A., et al.: Corros. Sci., 46, 1333 (2004),<br></p>

<p>Applications 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.<br>References El-Gamal, M. I., et al.: Bull. Korean Chem. Soc., 33, 1571-1576 (2012); Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);<br></p>

<p>Applications A product from the pyrolysis of phenylalanine.<br>References Kim, D., et al.: Bioorg. Med. Chem. Lett., 15, 2129 (2005), Che, W., et al.: Env. Toxicol. Pharmacol., 24, 11 (2007), Heitman, L., et al.: J. Med. Chem., 51, 4724 (2008),<br></p>

<p>Applications 2-(tert-Butylamino)-4-chloro-6-cyclopropylamino-1,3,5-triazine (cas# 26737-71-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Piperonyl Isobutyrate (cas# 5461-08-5) is a useful research chemical.<br></p>

<p>Applications A labelled imidazole, a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Arispe, N. et al.: Biophys. J., 95, 4879 (2008); Troesken, E.R. et al.: Endo. Res., 30, 387 (2004); Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2009);<br></p>

<p>Applications 4-Hydroxy-2-piperidinone is a synthetic intermediate in the synthesis of pharmaceutical goods.<br>References Vink, M.K.S., et al.: J. Org. Chem., 67, 7869 (2002);<br></p>

<p>Applications 5-Benzyl-4H-1,2,4-triazol-3-amine can be used as positive modulators of GABAA1 receptor with potent anticonvulsant activity and low toxicity.<br>References Huang, L., et.al.: Eur. J. Med. Chem., 185, 111824, (2020);<br></p>

<p>Applications 2-(Ethylthio)-1H-benzimidazole is the active substance or the active ingredient in the synthesis of the drug Metaprot. Performs a transplacental function: daily administration of bemithyl (20 mg/kg) from 6 th to 16 th day of pregnancy in female rats led to the decrease in fetal death after the implantation and increased fetal body weight.<br>References Kibal'chich, D. A., et al.: Eksperimental'naya i Klinicheskaya Farmakologiya, 74, 30 (2011); Bugaeva, L. I., et al.: Eksperimental'naya i Klinicheskaya Farmakologiya, 70, 40 (2007).<br></p>

<p>Applications 3-Chloropyridine-d4 (CAS# 1001003-95-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Dimethyl-5-pyrazolone (cas# 2749-59-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Oxo-2,2,6,6-tetramethylpiperidine-d17 (CAS# 52168-48-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Piperazine-N,N'-bis(2-ethanesulfonic Acid)-d18 (CAS# 352534-95-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,4-Dichloro-6-vinylpyrimidine used to synthesize polymers containing pyrimidine.<br>References Sugiki, T., et al.: J. Photopoly. Sci. Technol., 8, 9 (1995);<br></p>

<p>Applications 4-(azetidin-3-yl)-4H-1,2,4-triazole (cas# 1495939-85-9) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 2-Bromo-5-fluoropyridine-4-boronic acid<br></p>

<p>Stability Hygroscopic<br>Applications 5-(4-methylpiperazin-1-yl)pyridin-2-amine (cas# 571189-49-6) is a useful research chemical.<br></p>

<p>Applications A chiral fluoro-pyridine derivative used in the preparation of dihydropyrrolopyrimidinone derivatives for use as MARK inhibitors.<br></p>

<p>Applications 5-pyridin-3-ylfuran-2-carboxylic acid (cas# 56632-46-3) is a useful research chemical.<br></p>

<p>Applications 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester is used in various studies of stimulators of soluble guanylate cyclase.<br>References Straub, A., et al.: Bioorg. Med. Chem. Lett., 11, 781 (2001); Mittendorf, J., et al.: ChemMedChem, 4, 853 (2009); Straub, A., et al.: Bioorg. Med. Chem., 10, 1711 (2002)<br></p>

<p>Applications 2-​(Methoxy-​d3)​-​3-​(1-​methylethyl)​pyrazine is a useful compound in the study of isotope effect in gas liquid chromatography separation of deuterated and nondeuterated compounds using ionic liquid stationary phases.<br>References Schmarr, H., et al.: J. Chromatogr. A., 1270, 310 (2012);<br></p>

<p>Applications Ethyl-2-ethoxy-1-[[(2'-cyanobiphenyl-4-yl) methyl] benzimidazole]-7-carboxylate<br></p>