Eterocicli con azoto (N)

<p>Applications 1,3,5-trimethyl-1H-pyrazole-4-carboxylic acid (cas# 1125-29-7) is a useful research chemical.<br></p>

<p>Applications (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate used to prepare dipeptidyl peptidase IV (DPP-IV) inhibitors.<br>References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705 (2012); Sakashita, H., et al.: Bioorg. Med. Chem., 15, 641 (2007)<br></p>

<p>Applications 5-Bromo-2,4-diamino-6-hydroxypyrimidine (cas# 6312-72-7) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications 1-Ethyl-5-hydroxy-2-pyrrolidinone is an important organic solvent used in varnishing. Industrial solvent.<br>References Koch, H. et al. Arch. Toxicol., 88, 893 (2014); Koslitz, S. et al.: Toxicol. Lett., 231, 142 (2014);<br></p>

<p>Applications Oxidation and chlorination reagent.<br></p>

<p>Applications [2-(1-methyl-1H-pyrazol-3-yl)-1H-benzimidazol-1-yl]acetic acid (cas# 1171565-50-6) is a useful research chemical.<br></p>

<p>Applications (3-Chloropyrazin-2-yl)methanol (cas# 89283-32-9) is a useful reagent for the preparation of indazolylquinazolinones as inhibitors of human immunodeficiency virus replication.<br>References Gillis, E. P., et al.: PCT Int. Appl. (2020), WO 2020084492 A1<br></p>

<p>Stability Moisture Sensitive; Store in Freezer, Hygroscopic<br>Applications N-hydroxysuccinimide ester of palmitic acid. Esters of N-hydroxysuccinimide have been used for the preparation of N-acylamino acids, aminoacyl-tRNA, coenzyme A, thioglycolic acid, ceramides, etc.<br>References Lapidot, Y., et al.: J. Lipid Res., 8, 142 (1967); Lapidot, Y., et al.: Biochim. Biophys. Acta, 145, 292 (1967); Al-Arif, A., et al.: J. Lipid Res., 10, 344 (1969); Ong, D.E., and Brady, R.N., J. Lipid Res., 13, 819 (1972)<br></p>

<p>Impurity Minoxidil EP Impurity B<br>Applications 6-Chloro-pyrimidine-2,4-diamine (cas# 156-83-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Pyridine-2-aldoxime (cas# 873-69-8) is a useful research chemical.<br></p>

<p>Applications 2-(5-tert-Butyl-2-hydroxyphenyl)benzotriazole is a chemical reagent used in the synthesis of UV stabilizers in environmental waters.Used in the detection of UV light filters in sediment and sewage.<br>References Liu, R. et al.: Talanta., 120, 158 (2014); Zhang, Z. et al.: Env. Sci. Tech., 45, 3909 (2011);<br></p>

<p>Applications 4-(4-Chlorophenyl)-2,6-piperidinedione (cas# 84803-46-3) is a compound useful in organic synthesis.<br></p>

<p>Applications methyl 1-(2,4-difluorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylate (cas# 1202028-96-3) is a useful research chemical.<br></p>

<p>Applications Pyridinium Tribromide is a reagent used in the α-thiocyanation of ketones and has also been applied to the synthesis of β-adrenergic blocking agents (also known as β-blockers) for patients with heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hashemzadeh, M. et al.: Recent Pat. Cardiovasc. Drug Discov., 6, 175 (2011); Wu, L. et al.: Phosphorus, Sulfur Silicon Relat. Elem., 187, 748 (2012);<br></p>

<p>Applications 4-Vinylpyridine is used as a reagent in the synthesis of 4,4'-[9H-Carbazole-3,6-diyldi-(1E)-2,1-ethenediyl]bis[1-methyl-pyridinium Diiodide (C176070); a human quadruplex DNA stabilizer and telomerase inhibitor. 4-Vinylpyridine is also used as a reagent in the synthesis of spiro[cyclopropane[3H]indol]ones as polo-like kinase 4 inhibitors and orally bioavailable antitumor agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yang, D., et al.: J. Phys. Chem. A, 111, 9224 (2007); Chang, C., et al.: J. Chin. Chem. Soc-Taip., 50, 185 (2003); Sampson, P.B., et al.: J. Med. Chem., no vol., no pp., (2014 ahead of print)<br></p>

<p>Applications 4-(4-Chlorophenyl)-4-hydroxypiperidine (cas# 39512-49-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,4,6-Tris(pentadecafluoroheptyl)-1,3,5-triazine (CAS# 21674-38-4) is an s-triazine derivative (T773008) and is used as a reference standard in mass spectroscopy for m/z ratios between 600-1600.<br>References Aczel, T.; et al.: Anal. Chem., 40, 1917 (1968);<br></p>

<p>Applications L-Alanyl-L-proline is a dipeptide that contains a sterically constrained proline, a well-known turn inducer in proteins.<br>References Moriuchi, T., et al.: J. Organomet. Chem., 589, 50 (1999)<br></p>

<p>Applications The most characteristic degrdadation product of melanins. An important biomarker for Melatonin (M215000) metabolism.<br>References Shen, X., et al.: J. Med. Chem., 39, 2018 (1996), Xin, W., et a: Chem. Res. Toxicol., 13, 749 (2000), An, L., et al.: Food Chem. Toxicol., 44, 436 (2006),<br></p>

<p>Applications 3-Cyanopyridine is used in the preparation of arylthiazolines and arylimidazolines via dibromodimethylhydantoin-catalyzed condensation of aryl nitriles with ethylene diamine or aminoethanethiol.<br>References Hojati, S. F., et al.: Can. J. Chem., 88, 135 (2010);<br></p>

<p>Applications 6-(Dibutylamino)-1,3,5-triazine-2,4-dithiol (cas# 29529-99-5) is a useful research chemical.<br></p>

<p>Applications 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one is a benzimidazole derivative used in the preparation of neuroleptic and antiallergic agents.<br>References Strupczewski, J. et al.: J. Med. Chem., 28, 761 (1985); Freter, K. et al.: Arzneim.-Forsch., 35, 272 (1985);<br></p>

<p>Applications Oxazolidine Cabazitaxel is an impurity of Cabazitaxel (C046500) which is a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer.<br>References Agarwal, N. et al.: Fut. Oncol., 7, 15 (2011); Mita, A. et al.: Clin. Cancer Res., 15, 723 (2009); Figg, W.D. et al.: Cancer Biol. Ther., 10, 1233 (2010);<br></p>

<p>Applications 4-Oxo-6-(2-oxo-5-vinylpyrrolidin-1-yl)hexanoic Acid is derived from Ethyl Succinoyl Chloride (E818230), which is used in the synthesis of bivalent ligands for D2/D3 dopamine receptors. Also used in the preparation of antimicrobial pyrrolo-isoquinolinones. Vigabatrin Impurity 2<br>References Gogoi, S. et al.: ACS Med. Chem. Lett., 3, 991 (2012)<br></p>

<p>Impurity Esomeprazol EP Impurity A/ Omeprazole EP Impurity A<br>Applications 5-Methoxy-2-mercaptobenzimidazole (Esomeprazol EP Impurity A) is used in the synthesis of COX-2 inhibitors<br>References Frechette, S., et al.: Bioorg. Med. Chem. Lett., 18, 1502 (2008), Zhang, R., et al.: Eur. J. Med. Chem., 44, 3771 (2009),<br></p>

<p>Applications 3-Chloro-2-hydrazinopyridine (cas# 22841-92-5) is a useful research chemical.<br></p>

<p>Applications 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is used in preparation and structure of alkaline earth iodide phosphine oxide and urea complexes as reactant or reagents.<br>References Fitts, Lacey S., et al.: New J. of Chem., (2016); Hall, Jessica E., et al.: Angew. Chem. Int. Ed., 55, 11153-11157 (2016)<br></p>

<p>Applications 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Urazole (cas# 3232-84-6) is a useful research chemical.<br></p>

<p>Applications 1,2-DIMETHYLIMIDAZOLE (cas# 1739-84-0) is a useful research chemical.<br></p>

<p>Applications 2-(4,6-Diphenyl-1,3,5-triazine-2-yl)-5-[(hexyl)oxy]phenol is used as a light stabilizer/UV absorber for polyethylene phthalate polymers intended for use in contact with food.<br>References Food and Drug Administration, HHS: Fed. Reg., 63, 43874 (1998); Fechine, G.J.M. et al.: Polym. Degrad. Stab., 75, 153 (2002);<br></p>

<p>Applications Methyl 5-Ethyl-2-pyridine-carboxylate (cas# 13509-14-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Used for preparation of thieno-tetrahydropyridines useful as class III antiarrhythmic agents.<br>References Bahekar, R., et al.: Bioorg. Med. Chem., 15, 5950 (2007), Hayakawa, M., et al.: Bioorg. Med. Chem. Lett., 17, 2438 (2007),<br></p>

<p>Applications 1-(2,3-Epoxypropyl)-2-nitroimidazole is an intermediate in the synthesis of Pimonidazole-d10 (P447814). Isotope labelled Pimonidazole (P447813) is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It abels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.<br>References Sato et al.: PLoS One 11 e0165946 PMID:(2016); Bennewith et al.: Cancer Res. 62 6827 PMID: 12460894, (2002)<br></p>

<p>Applications 4-(2-cyclopropyl-1,3-oxazol-5-yl)aniline (cas# 1031130-92-3) is a useful research chemical.<br></p>

<p>Applications 4'-Bromo-2,2':6',2''-terpyridine (cas# 149817-62-9) is a useful research chemical.<br></p>

<p>Applications Tolyltriazole acts as a corrosive inhibitor and is used as corrosion protection on top of metals such as copper.<br>References Hseih, M. et al.: Ind. Eng. Chem. Res., 49, 7313 (2010);<br></p>

<p>Applications 1-(4-Hydrazinylbenzyl)-1H-1,2,4-triazole (cas# 212248-62-9) is a useful research chemical.<br></p>

<p>Applications 4-Nitro-1H-imidazole-1-ethanol<br></p>

<p>Applications 2-Butyl-5-chloro-1H-imidazole (cas# 158365-99-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Pyrazine 1,4-Dioxide (cas# 2423-84-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Ethyl-2,4-dimethyl-1H-pyrrole is a important diagnostic compound for pyrrole disorder or pyroluria, an abnormality in biochemistry resulting in overproduction of pyrrole molecules and resulting in improper hemoglobin synthesis.<br>References Walsh, W.J., et al.: Physiol. Behav., 82, 835 (2004); Inrvine, D.G., et al.: Clin. Chem., 24, 2069 (1978);<br></p>

<p>Applications N-(chloroacetoxy)succinimide is a N-hydroxysuccinimide ester of a simple carboxylic acid. N-(chloroacetoxy)succinimide is used in the preparation of organometallic complexes and other synthetic probes for the labeling of proteins.<br>References Salmain, M. et al.: Bioconj. Chem., 4, 425 (1993); Nonaka, H. et al.: J. AM. Chem. Soc., 129, 15777 (2007);<br></p>

<p>Applications 1,5,8,12-Tetrakis[4,6-bis(N-butyl-N-1,2,2,6,6-pentamethyl-4-piperidylamino)-1,3,5-triazin-2-yl]-1,5,8,12-tetraazadodecane is used as a light/thermal stabilizer in olefin polymers intended for use in contact with food.<br>References Kohler, D.R. et al.: Polym. Degrad. Stab., 63, 165 (1998); The Food and Drug Administration: Fed. Reg., 65, 16314 (2000);<br></p>

<p>Applications 1-Isopropenyl-2-benzimidazolidinone (cas# 52099-72-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3,5-Dimethyl-4-nitropyridine 1-Oxide is an intermediate used to prepare 2-[(2-pyridylmethyl)thio or -sulfinyl]benzimidazoles as antiulcer agents.<br>References Nohara, A., et al.: U.S., US 4689333 A 19870825. (1987)<br></p>

<p>Applications 5-Hydroxycytosine, is been identified as an anomalous base of phage H-17 DNA. It is also a monosubstituted cytosine, as nucleotide-base antimetabolite-type potential anticarcinogen.<br>References Khromov, I. S. Doklady Akademii Nauk SSSR, 240, 1486 (1978); Ladik, J., et al.: Magyar Kemiai Folyoirat, 76, 589 (1970);<br></p>

<p>Applications 2,6-diethylpyrazine (cas# 13067-27-1) is a useful research chemical.<br></p>

<p>Applications 2-Aminopyrimidine is used in the synthesis of sulfonamides as isoform-selective inhibitors with efficacy in rodent pain models.<br>References Focken, T. et al.: ACS Med. Chem., 7, 277 (2016); Reddy, M. et al.: Bioorg. Med. Chem., 24, 521 (2016);<br></p>

<p>Impurity Clavulanate Potassium EP Impurity A<br>Applications 2,5-Pyrazinediethanol (Clavulanate Potassium EP Impurity A) is an impurity of Clavulanic acid (C563750). High concentrations of Clavulanic acid but not of its degradation products decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus.<br>References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003), Alper, H., et al.: Science, 314, 1565 (2006), Brethauer, S., et al.: Biotechnol. Bioeng., 98, 356 (2007),<br></p>

<p>Applications 5-(4-Chlorobutyl)-1-cyclohexyltetrazole-d11 (cas# 1073608-19-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Amino-3,5-dibromopyrazine is used in the preparation of conjugated polymers for neurotoxin detection. 2-Amino-3,5-dibromopyrazine is an intermediate in the preparation of rho kinase (ROCK) inhibitors.<br>References Thomas, J. et al.: Polym. Prepr., 46, 1211 (2005); Henderson, A.J. et al.: Bioorg. Med. Chem. Lett., 20, 1137 (2010);<br></p>

<p>Applications 3,6-Bis(4-chlorophenyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (cas# 84632-65-5) is a useful research chemical.<br></p>

<p>Applications Pyridin-3-yl dimethylcarbamate (cas# 51581-32-9) is a useful research chemical.<br></p>

<p>Applications Orotic Acid Monosodium Salt is used in the formation of a complex with lanthanium(III) which displats cytotoxic activity on different tumor cell lines.Also, it is the unlabeled form of Orotic Acid-15N2 Monosodium Salt (O691517), which is an intermediate used in the synthesis of Orotic Acid-15N2 Monohydrate (O691504), which is a labeled analogue of Orotic Acid Monohydrade (O691500), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.<br>References Kostova, I., et al.: Int. J. Curr. Chem., 1, 271-280 (2010)<br></p>

<p>Applications A labelled imidazole, a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Arispe, N. et al.: Biophys. J., 95, 4879 (2008); Troesken, E.R. et al.: Endo. Res., 30, 387 (2004); Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2009);<br></p>

<p>Applications Pyridinium p-Toluenesulfate is used in the synthesis of a subdomain of the cytochrome P450 BM3 enzyme, for use in screening systems for drug candidates.<br>References Erkelenz, M. et al.: J. Am. Chem. Soc., 133, 16111 (2011);<br></p>

<p>Applications A free radical scavenger; may be used for prophylaxis and treatment of IRI.<br>References Flather, M., et al.: Lancet, 355, 1575 (2000), Sasso, F., et al.: Metabolism, 52, 675 (2003), Kass, D., et al.: Circ. Res., 94, 1533 (2004), Murdoch, C., et al.: Cardiovasc Res., 71, 208 (2006),<br></p>

<p>Applications 2-Nitrosopyridine is a useful reactant in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, Xing, et al.: J. of Org. Chem., 84(7), 4402-4412 (2019);Zhang, Jingchuan, et al.: Chem. - A Euro. J., 24(17), 4289-4293 (2018)<br></p>

<p>Applications 5-Bromo-2-hydroxypyrimidine (cas# 38353-06-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,4-Diaminopyrimidine-5-carbonitrile is used as an intermediate for the preparation of medicines and agrochemicals (1).<br>References (1) Otzen, T., et al.: J. Med. Chem., 47, 240 (2004)<br></p>

<p>Applications s-Triazine-1,3,5-triethanol (cas# 4719-04-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Amino-5-pyrimidinol (cas# 143489-45-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Mercaptopyridine N-oxide sodium salt is a bidentate complexing agent used to chelate transition metals at a pH range of 0.7-7.4. 2-Mercaptopyridine N-oxide sodium salt is also used as a selective absorptiometric reagent in the determination of palladium.<br>References Edrissi, M., et al.: J. Mater. Sci.-Mater. El., 22, 328 (2011); Edrissi, M., et al.: Microchem. J., 16, 526 (1971); Thakur, M., et al.: J. Nucl. Med., 26, 510 (1985)<br></p>

<p>Applications 1-(oxan-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (cas# 1487610-80-9) is a useful research chemical.<br></p>

<p>Stability Hygroscopic, forms hydrazoic acid on prolonged storage and on contact with water<br>Applications 1H-Imidazole-1-sulfonyl azide, HCl salt (cas# 952234-36-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 4-Hydroxy-1,1-dimethylpiperidinium Bromide is a derivative of 4-Hydroxypiperidine (H950845); a reagent used for the synthesis of Acridine (A190900) derivatives and fibrinogen receptor antagonists.<br>References Yang, D. et al.: Macromol., 35, 5304 (2002); Harrison, R.J. et al.: Bioorg. Med. Chem. Lett., 9, 2463 (1999)<br></p>

<p>Applications 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one (cas# 545445-44-1) is a useful research chemical.<br></p>

<p>Applications An intermediate in the preparation of Piperidinyloxy free radical derivatives.<br>References Irie, O., et al.: Bioorg. Med. Chem. Lett., 18, 5280 (2008),<br></p>

<p>Applications (2-oxo-4-phenylpyrrolidin-1-yl)acetic Acid (cas# 67118-34-7) is a useful research chemical.<br></p>

<p>Applications N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxybutanediamide, is a bifunctional chelator.<br></p>

<p>Applications (R)-4-(Hydroxymethyl)oxazolidin-2-one, is a building block used in various chemical synthesis.<br></p>

<p>Applications 1H-1,2,3-Triazole-1-acetic acid (cas# 4314-22-1) is a useful research chemical.<br></p>

<p>Applications 3-Amino-6-chloropyridazine (cas# 5469-69-2) is a compound useful in organic synthesis.<br></p>

<p>Impurity Droperidol Impurity 4<br>Applications 4-(2-Nitroanilino)pyridine can be used to increase the yield of 4-(2-Aminoanilino)pyridine (A583160) dihydrochloride by hydrogenation in the presence of a Ni-Cr catalyst. Droperidol Impurity 4.<br>References Avots, A., et al.: U.S.S.R., SU 1318592 A1 19870623<br></p>

<p>Applications 2,4-Dihydroxypyrrolo[2,3-d]pyrimidine (cas# 39929-79-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine (cas# 2387-48-6) is a compound useful in organic synthesis.<br></p>

<p>Applications A synthetic intermediate.<br>References Blakemore, R., et al.: Eur. J. Med. Chem., 22, 91 (1987),<br></p>

<p>Applications 5-(2-Fluorophenyl)-1H-tetrazole is used in the synthetic preparation of novel tetrazole derivatives as positive allosteric modulators of metabotropic glutamate receptors useful in treatment and prevention of CNS diseases and diseases-modulated by mGluR5 receptors.<br>References Gagliardi, S.; et al.: PCT Int. Appl. 45 pp. Patent 2006 CODEN:PIXXD2<br></p>

<p>Applications 2-Chloro-3-(trifluoromethyl)pyridine is a building block used to prepare various high affinity TRPV1 (VR1) vanilloid receptor antagonists.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Swanson, D., et al.: J. Med. Chem., 48, 1857 (2005); Rami, H., et al.: Bioorg. Med. Chem. Lett., 16, 3287 (2006)<br></p>

<p>Applications N-Octylpyridin-4-amine is used in the synthesis of antimicrobial agent Octenidine (O239150), as chelating agent.<br>References Bailey, D.M., et al.: J. Med. Chem., 27, 1457 (1984),<br></p>

<p>Applications An intermediate in the synthesis of Prasugrel (P701150).<br></p>

<p>Applications Used in the synthesis of thieno[3,2-a]quinolizidines and attempts to prepare Papaverine analogs.<br>References Schmid, H., et al.: Helv. Chim. Acta, 32, 960 (1949),<br></p>

<p>Applications An intermediate in the synthesis of rabeprazole (R070500).<br></p>

<p>Stability Hygroscopic<br>Applications 4-Diphenylmethoxypiperidine, HCl<br></p>

<p>Applications N-Benzyl-4-carboethoxypiperidine (cas# 24228-40-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Chlorobenzotriazole is a good inhibitor; it decreases anodic and cathodic reaction rates, and the highest inhibition efficiency was 91.2%. The inhibitory effect of 5-chlorobenzotriazole is explained by the formation of the layer on the copper surface.<br>References Simonovic, Ana T., et al.: ACS Omeg., 5, 12832-12841 (2020);<br></p>

<p>Impurity Cefoperazone EP Impurity C<br>Applications N-Methyl-5-tetrazolethiol (Cefoperazone EP Impurity C) is an impurity of Cefoperazone.<br>References Kitson, T., et al.: Biochem. J., 175, 83 (1978), Elenbaas, R., et al.: Clin. Pharmacol. Ther., 32, 347(1982),<br></p>

<p>Applications 3-(4-iodo-1H-pyrazol-1-yl)propanenitrile (cas# 88393-88-8) is a useful research chemical.<br></p>

<p>Applications 1-(4-Nitrophenyl)-2-piperidinone is used in the synthesis of inhibitors of blood coagulation factor Xa.<br>References Pinto, D., et al.: J. Med. Chem., 50, 5339 (2007); Xing, J., et al.: Eur. J. Med. Chem., 95, 388 (2015)<br></p>