Composti eterociclici

<p>Applications pyridazin-4-ylmethanol (cas# 50901-43-4) is a useful research chemical.<br></p>

<p>Applications 2-Aminothiazole-4-carboxamide is a useful intermediate for organic synthesis and other chemical processes.<br>References Sanghvi, Y. S., et al.: J. Heterocycl. Chem., 25, 623 (1988); Wu, J., et al.: Bioorg. Med. Chem. Lett., 17, 4664 (2007)<br></p>

<p>Applications 4,4-dimethyldihydrofuran-2,3-dione (cas# 13031-04-4) is a useful research chemical.<br></p>

<p>Applications (2,4-Dioxo-thiazolidin-3-yl)-acetic Acid is a useful compound for preparation of novel thiazolidinedione-​hydroxamates as Zmp1 inhibitors.<br>References Slachtova, V., et al.: Eur. J. Med. Chem., 185, 111812 (2020)<br></p>

<p>Applications 2-carboxythiophene-3-boronic acid (cas# 5503-74-2) is a useful research chemical.<br></p>

<p>Impurity Abacavir - In House Impurity<br>Applications rac 2-Azabicyclo[2.2.1]hept-5-en-3-one (Abacavir - In House Impurity) is a useful reagent in the synthesis of carbocyclic sugar amines, carbanucleosides, and carbocyclic dinucleotide analogues (1). rac 2-Azabicyclo[2.2.1]hept-5-en-3-one is also an intermediate of Abacavir (A104990), a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Slama, J.T., et al.: Biochemistry, 27, 183 (1988) (2) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (3) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>

<p>Applications Tetrahydrofuran-2,5-dicarboxylic acid (CAS# 6338-43-8) is a useful research chemical compound.<br></p>

<p>Stability Hygroscopic<br>Applications 3-(1-Nitroethyl)-2-benzofuran-1(3H)-one (cas# 79017-08-6) is a useful research chemical.<br></p>

<p>Applications Methyl Hyroxy-2-(tetrahydro-2H-pyran-4-yl)acetate is a useful research intermediate for organic synthesis.<br></p>