Building Blocks

<p>Applications Methyl trans-4-Bromo-2-butenoate is used as a reagent in the synthesis of several organic compounds including that of dimethoxy ketals and ketones via electrochemical oxidative decarboxylation of malonic acids.<br>References Ma, X., et al.: Org. Lett., 17, 4690 (2015);<br></p>

<p>Applications Benzylmethyl-d3-amine HCl (CAS# 122025-10-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications A potent γ-ketoaldehyde scavenger that has been shown to protects cardiac sodium channel (NaV1.5) from oxidant-induced inactivation<br>References Zagol-Ikapitte, I. et al.: Pharmaceutics, 2, 18 (2010); Nakajima, T. et al.: J. Mol. Cell. Cardiol., 48, 352 (2010); Davies, S.S. et al.: Biochem., 45, 15756 (2006);<br></p>

<p>Applications 4-Hydroxy-1-methylpiperidine<br></p>

<p>Applications Methyl 2-Amino-5-bromobenzoate is used as a potential PqsD inhibitor against pseudomonas aeruginosa infections.<br>References Weidel, E. et al.: J. Med. Chem., 56, 6146 (2013);<br></p>

<p>Applications Mono-tert-butyl Malonate is a useful synthetic intermediate. It can be used to prepare quinoline-based zinc metallo-aminopeptidase inhibitors with antimalarial activity. It can also be used to synthesize truncated aminoglycoside-CoA bisubstrate analogs via chemo- and regioselective coupling reaction of amine and thiols, as inhibitors of aminoglycoside 6'-N-acetyltransferase Ii<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Flipo, M., et al.: Bioorg. Med. Chem. Lett., 13, 2659 (2003); Gao, F., et al.: J. Med. Chem., 49, 5273 (2006)<br></p>

<p>Applications N-Hydroxybenzylamine Hydrochloride, is a versatile intermediate for the synthesis of various pharmaceutical compounds. It is used for the preparation of Ticagrelor (T437700) derivatives as novel antiplatelet agents.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007);<br></p>

<p>Applications Potassium 4-Carboxybenzenesulfonate is used as a reactant for the synthesis of Potassium and Rubidium Arenesulfonates which shows coordination behavior towards the anions.<br>References Gunderman, B., et al.:Inorg. Chem., 33,2924(1994)<br></p>

<p>Stability Hygroscopic<br>Applications 4-Hydroxy-3-methyoxybenzyl Alcohol is used in the anti-asthmatic activity of phenolic compounds from the roots of Gastrodia elata Bl. Chemical composition, antioxidant and antibacterial activities of lemon peel essential oil.<br>References Jang, Y. W., et al.: Int. Immunopharmacol., 10, 147 (2010); Zhang, B., et al.: Shipin Gongye Keji, 36, 126 (2015)<br></p>

<p>Stability Light Sensitive<br>Applications 4-(1-Naphthylvinyl)pyridine (cas# 16375-56-7) is a useful research chemical.<br></p>

<p>Stability Air Sensitive, Volatile<br>Applications Pivalaldehyde (cas# 630-19-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methyl phenyl sulfone (cas# 3112-85-4) is a useful research chemical.<br></p>

<p>Applications Trifluorothymine is an antitumor and antiviral agent. Trifluorothymine was found in patients’ urine as a metabolite of Trifluorothymidine as cancer treatment.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cirak, C., et al.: J. Mol. Model., 18, 4453 (2012); Dexter, D., et al.: Cancer Res., 32, 247 (1972)<br></p>

<p>Applications Octadecanoic-16,16,17,17,18,18,18-d7 Acid (CAS# 951209-59-9) is a useful isotopically labeled research compound.<br></p>