Chetoni

<p>Stability Moisture Sensitive<br>Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.<br>References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);<br></p>

<p>Applications 2-Heptacosanone is a useful research chemical for organic synthesis and other chemical processes.<br>References Dastillung, M., et al.: J. Chem. Res. Synopses, 5, 166 (1980), Liu, Q., et al.: Advan. Mater. Res., 230, 842 (2011)<br></p>

<p>Applications Methyl 2-Cyclopentanonecarboxylate is used in the synthesis of functionalized ketones.<br>References Mashima, K. et al.: J. Org. Chem., 59, 3064 (1994); Hamashima, Y. et al.: J. Am. Chem. Soc., 124, 11240 (2002);<br></p>

<p>Applications 4-Cyanocyclohexanone is used to prepare nicotinamides as PDE4 D isoenzymes inhibitors. It is also used as an anthranilic acid replacement in niacin receptor agonist.<br>References Marfat, A., et al.: PCT Int. Appl. (1998), WO 9845268 A1 19981015; Schmidt, D., et al.: Bioorg. Med. Chem. lett., 20, 3426 (2010)<br></p>

<p>Applications 1-(1,3-Benzodioxol-5-yl)-1-hexanone is an intermediate used in the synthesis of 1-(1,3-benzodioxol-5-yl)-2-(1-pyrrolidinyl)-1-Hexanone (B207110), which is also known as MDPHP, is a synthetic cathinone.<br>References Fowble, K. L.; et al.: Talanta, 179, 546 (2018).<br></p>

<p>Applications 2,2-Diethoxycycloheptanone is an intermediate in the synthesis of 1,2-Cycloheptanedione (C987255), a reagent in the synthesis of 3,3’-Polymethylene-2,2’-bibenzo[b]-1,10-phenanthrolines.<br>References Rahman, A. F. M., et al.: Heterocycles, 75, 871-877 (2008)<br></p>

<p>Applications PBD-5,11-dione (cas# 18877-34-4) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of benzopyran derivatives for their antiinflammatory properties.<br></p>

<p>Applications (E)-1-(Benzo[b]​thiophen-​2-​yl)ethanone Oxime is an isomer of N-​(1-​Benzo[b]​thiophen-​2-​yl-​ethyl)​-​hydroxylamine a reagent used in the preparation of Zileuton, an anti-asthmatic drug.<br>References Guinchard, X. et al.: J. Org. Chem., 73, 2028 (2008)<br></p>

<p>Applications 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).<br>References Bastien, D., et al.: J. Med. Chem., 55, 3182 (2012)<br></p>

<p>Applications 2-Cyclopentylcyclopentanone (cas# 4884-24-6) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxy-cyclohexanone is a chemical reagent used in organic synthesis. Used in enantioselective conjugate-addition reactions as well as the cross coupling of enantioenriched secondary potassium β-trifluoroboratoamides.<br>References Molander, G. et al.: Adv. Synth. Catal., 355, 3037 (2013); Kitanosono, T. et al.: Chem. Asian J., 9, 179 (2014);<br></p>

<p>Applications Cyclopentanone-2-carbonitrile (cas# 2941-29-9) is a useful research chemical. It acts as a reagent in the preparation of quinolines<br>References Larsen, R. D., et al.: Science of Synthesis, 15, 389 (2005)<br></p>

<p>Stability Moisture Sensitive<br>Applications 1-(2-oxopropyl)-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione (cas# 57384-79-9) is a useful research chemical.<br></p>

<p>Applications (2R,​3S,​4S,​5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone was used in the synthetic preparation of N-substituted valiolamine derivatives.<br>References Fukase, H., et al.: J. Org. Chem., 57, 3642 (1992);<br></p>

<p>Applications 5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione (cas# 92260-81-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,5-dimethoxycyclohexa-2,5-diene-1,4-dione (cas# 3117-03-1) is a useful research chemical.<br></p>

<p>Applications 2-Hexanone is used in various organic chemical syntheses. It is used in the synthesis of (+/-)-monomorine. It is also used in the preparation of alcohols by transfer hydrogenation of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Le, T. et al.: Tetrahedron Lett., 53, 5660 (2012); Ikhile, M. et al.: Tetrahedron Lett., 53, 4925 (2012);<br></p>

<p>Applications 2-Hexylidenecyclopentanone is a compound that is found in fragrance.<br>References Scognamiglio, J., et al.: Food Chem. Tox., 3, S577 (2012)<br></p>

<p>Applications 1-Cyclohexylethanone is used in the synthesis of thiosemicarbazide derivatives which exhibits biological activity.<br>References Venkatesh, K., et al.: J. Chem. Pharm. Res., 7, 437-445 (2015)<br></p>

<p>Applications 4-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-2-butanone is a useful synthetic intermediate. It is a reagent used to prepare moverastin derivatives, an inhibitor of tumor cell migration. It can also be used in preparation of substituted alkene derivatives capable of releasing fragrant compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sawada, M., et al.: Bioorg. Med. Chem. Lett., 21, 1385 (2011);<br></p>

<p>Applications Cyclohexyl phenyl ketone is a useful research chemical in organic synthesis.<br>References Yang, Tonghao, et al.: Org. Let., 20(7), 1875-1879 (2018);Jarava-Barrera, Carlos, et al.: Chem. - A Euro. J., 23(69), 17478-17481 (2017)<br></p>

<p>Applications 1-[2-Hydroxy-5-(2-hydroxyethyl)phenyl]-ethanone (cas# 58282-51-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 5β-Estrane-3,17-dione is an intermediate in the synthesis of neuroactive steroids useful in the treatment of CNS-related diseases.<br>References PCT Int. Appl. (2015), WO 2015180679 A1 20151203;<br></p>

<p>Applications 1-Cyclopropyl-1,3-butanedione is a reagent in regioselective synthesis of pyrazolylpyrazolopyrimidine derivatives in aqueous medium for antimicrobial agents.<br>References Novinson, T., et al.: J. Med. Chem., 17, 645 (1974); Aggarwal, R., et al.: Eur. J. Med. Chem., 46, 3038 (2011)<br></p>

<p>Applications Cyclohexyl Vinyl Ketone is a reagent used in the synthesis of α,β-unsaturated carbonyl compounds which are aminotrifluoromethylathiolated.<br>References Xiao, Q. et al.: Org. LEtt., 17, 6090 (2015) ;<br></p>

<p>Applications 3-Isochromanone can be used to prepare an organic catalyst.<br>References Wu, G., et.al.: Faming Zhuanli Shenqing, 31, (2021);<br></p>

<p>Stability Unstable in Aqueous Solution<br>Applications (±)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone is a volatile organic compound used in the silylation of alcohols,<br>References D'Sa, B.A. et al.: J. Org. Chem., 62, 5057 (1997);<br></p>

<p>Applications 1,1'-[1]Benzothieno[3,2-b][1]benzothiophene-2,7-diylbis[1-octanone] is the intermediate in the synthesis of C8-BTBT (C015010), which is a soluble organic semicoductor used in solution-processed organic field-effect transistors.<br>References Ebata, H., et al.: J. Am. Chem. Soc., 129, 15732 (2007); Izawa, T., et al.: Adv. Mat., 20, 3388 (2008)<br></p>

<p>Applications 2-Isobutyrylcyclohexanone (cas# 39207-65-3) is a useful research chemical.<br></p>

<p>Applications 2-Acetylcyclohexanone is used in the synthesis of 1-(pyridyl)ethanol derivatives that can reduce keto-esters and ketones. Also used in the synthesis of phenothiazine derivatives that can inhibit protein farnesyltransferase molecules and some that show anti-proliferative activity.<br>References Baciu-Atudosie, L. et al.: Bioorg. Med. Chem. Lett., 22, 6896 (2012); Kawano, S. et al.: Biosci. Biotech. Biochem., 75, 1055 (2011);<br></p>

<p>Applications 3,​3-​Dimethyl-​2,​4-​pentanedione is used in asymmetric hydrosilation of ketones.<br>References Kuwano, R., et al.: Bull. Chem. Soc. Jpn., 73, 485 (2000).<br></p>

<p>Applications (E)-2-Heptylidenecyclopentanone, is a common substance that is found in fragrances.<br></p>

<p>Applications 4-(Morpholin-4-yl)cyclohexanone is a useful synthetic intermediate. It was used to synthesize diastereomeric 3,6-diaminobicyclo[3.1.0]hexane derivatives.<br>References Vilsmaier, E., et al.: Synthesis, 12, 1142 (1991)<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Acetoxymethyl Vinyl Ketone (cas# 38982-28-4) is a compound useful in organic synthesis.<br>References Zingel, V., et al.: Eur. J. Med. Chem., 25, 673 (1990), Sabourin, P., et al.: Carcinogenesis, 13, 1633 (1992),<br></p>

<p>Applications 1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfenic acid proteins. It was also used to synthesize enaminones with possible anticonvulsant activity.<br>References Qian, J., et al.: Chem. Comm., 47, 9203 (2011); Scott, K., et al.: J. Med. Chem., 36, 1947 (1993)<br></p>

<p>Applications 2-ETHYL-1-INDANONE (cas# 22351-56-0) is a useful research chemical.<br></p>

<p>Applications (5Z,9Z,13Z)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.<br>References Murakami, M., et al.: Arzneim.-Forsch., 31, 799 (1981); Nishizawa, Y., et al.: Xenobiotica, 17, 575 (1987)<br></p>