Standard farmaceutici
Gli standard farmaceutici sono un insieme completo di materiali di riferimento essenziali per garantire la sicurezza, l'efficacia e la qualità dei prodotti farmaceutici. Questa categoria include standard per ingredienti farmaceutici attivi (API), che sono i componenti principali responsabili degli effetti terapeutici. Inoltre, copre composti e metaboliti rilevanti sia per l'industria farmaceutica che veterinaria, fornendo punti di riferimento per la misurazione e l'analisi precisa di queste sostanze. Gli standard di controllo delle nitrosammine sono cruciali per rilevare e mitigare le nitrosammine potenzialmente dannose nelle formulazioni di farmaci. Gli standard di tossicologia aiutano a valutare la sicurezza e i potenziali effetti avversi dei composti farmaceutici. Inoltre, gli standard per attivatori e inibitori enzimatici sono vitali per la ricerca e lo sviluppo, consentendo studi precisi delle vie biochimiche e dei meccanismi d'azione dei farmaci. Questi standard farmaceutici sono strumenti indispensabili per la conformità normativa, il controllo di qualità e la ricerca, garantendo che i prodotti farmaceutici soddisfino rigorosi criteri di sicurezza ed efficacia.
Sottocategorie di "Standard farmaceutici"
- APIs per la ricerca e le impurità(273.647 prodotti)
- Attivatori e inibitori enzimatici(2.827 prodotti)
- Nitrosamine(2.605 prodotti)
- Composti e metaboliti farmaceutici e veterinari(2.602 prodotti)
- Tossicologia(13.652 prodotti)
Trovati 7836 prodotti di "Standard farmaceutici"
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2-Nonenedioic Acid
CAS:Prodotto controllato<p>Applications 2-Nonenedioic Acid is an impurity of Azelaic acid (A808140) which is an antiacne agent.<br>References Bladon, P.T., et al.: Br. J. Dermatol., 114, 493 (1986)<br></p>Formula:C9H14O4Colore e forma:White To Light BeigePeso molecolare:186.21Thioaildenafil
CAS:<p>Applications A new Sildenafil (S435000) analogue.<br>References Balayssac, S., et al.: J. Pharm. Biomed. Anal., 50, 602 (2009),<br></p>Formula:C23H32N6O3S2Colore e forma:NeatPeso molecolare:504.67Drotaveraldine
CAS:Prodotto controllato<p>Applications A metabolite of Drotaverine (D689700).<br>References Lalla, J.K., et al.: J. Pharma. Biomed. Anal., 11, 385 (1993),<br></p>Formula:C24H29NO5Colore e forma:BeigePeso molecolare:411.49Anastrozole Monoamide
CAS:<p>Impurity Anastrozole Monoamide Impurity<br>Applications Anastrozole Monoamide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formula:C17H21N5OColore e forma:WhitePeso molecolare:311.38Dimefline Hydrochloride
CAS:Prodotto controllato<p>Applications Dimefline is a new respiratory stimulant drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Edwards, J.M., et al.: J. Nat. Prod., 42, 85 (1979), Setnikar, I., et al.: Arzneim.-Forsch., 11 1109 (1961),<br></p>Formula:C20H21NO3·HClColore e forma:NeatPeso molecolare:359.85Methyl-1-naphthalenemethylamine
CAS:<p>Impurity Terbinafine EP Impurity A; Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications Terbinafine EP Impurity A. Terbinafine BP Impurity A. Terbinafine USP Related Compound A<br></p>Formula:C12H13NColore e forma:OrangePeso molecolare:171.24Boldenone 17-Sulfate TEA
CAS:Prodotto controllato<p>Applications The major metabolite of Boldenone, an anabolic steroid.<br>References Fotsis, T., et al.: J. Steroid Biochem., 28, 203 (1987), Song, Y., et al.: Arch. Pharm. Res., 23, 599 (2000), Buiarelli, F., et al.: Anal. Chim. Acta, 526, 113 (2004), Poelmans, S., et al.: Food Addit. Contam., 22, 808 (2005),<br></p>Formula:C19H26O5S•C6H15NColore e forma:Off-White To BeigePeso molecolare:366.472-Nitrophenol-3,4,5,6-d4
CAS:Prodotto controllato<p>Applications 2-Nitrophenol-3,4,5,6-d4 (CAS# 93951-78-1) is a useful isotopically labeled research compound.<br></p>Formula:C6D4HNO3Colore e forma:NeatPeso molecolare:143.13(R,S)-Equol
CAS:Prodotto controllato<p>Applications (R,S)-Equol is a human urinary metabolite of the soy isoflavones Daidzein (D103500).<br>References Heinonen, S., et al.: Anal. Biochem., 274, 211 (1999), Setchell, K., et al.: J. Nutr., 132, 3577 (2002), Thigpen, J., et al.: Comp. Med., 53, 607 (2003), Yee, S., et al.: Food Chem. Toxicol., 46, 2713 (2008),<br></p>Formula:C15H14O3Colore e forma:NeatPeso molecolare:242.27Selenosulfuric Acid Dipotassium Salt, Technical Grade
CAS:Prodotto controllato<p>Applications Selenosulfuric Acid Disodium Salt is used in the synthesis of CdSe photocatalysts with enhanced photocatalytic ativitys. Possible application towards industrial wastewater treatment and pollutant removal.<br>References Lim, C. et al.: Bull. Korean Chem Soc., 32, 1657 (2011);<br></p>Formula:K2O3SSeColore e forma:NeatPeso molecolare:237.22N-Formyl Varenicline
CAS:Prodotto controllato<p>Applications A metabolite of Varenicline. Metabolite M5.<br>References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005),<br></p>Formula:C14H13N3OColore e forma:NeatPeso molecolare:239.27Dihydro Caffeic Acid 3-O-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Caffeic Acid. Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Formula:C9H8Na2O7SColore e forma:NeatPeso molecolare:306.20Betamethasone 17-Propionate
CAS:Prodotto controllato<p>Impurity Clobetasol Propionate EP Impurity A / Betamethasone Dipropionate EP Impurity B<br>Applications Betamethasone 17-Propionate (Clobetasol Propionate EP Impurity A) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Formula:C25H33FO6Colore e forma:Off-WhitePeso molecolare:448.52Pinic Acid (Diastereomeric Mixture)
CAS:Prodotto controllato<p>Applications Pinic Acid (Diastereomeric Mixture) can be used to prepare pinic acid diamides as herbicides.<br>References Zou,R., et al.: Guangxi Daxue Xuebao, Ziran Kexueban, 36, 463 (2011);<br></p>Formula:C9H14O4Colore e forma:NeatPeso molecolare:186.21Tetrachloroauric Acid
CAS:Prodotto controllato<p>Applications Tetrachloroauric Acid, is used for the recovery, concentrating, purification, and analytical determinations of gold. It is the precursor used in the purification of gold by electrolysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mironov, I. V., et al.: Russian J. Inorg. Chem., 57, 610 (2012); Feather, A., et al.: J. Southern Africa Inst. mining Metal., 169 (1997);<br></p>Formula:AuCl3·ClHColore e forma:NeatPeso molecolare:339.79Igepal CO-520
CAS:<p>Applications Igepal is a nonionic surfactant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sedgqwick, M. et al.: Langmuir, 25, 5496 (2009);<br></p>Formula:(C2H4O)n·C15H24OColore e forma:ColourlessPerilla Ketone
CAS:Prodotto controllato<p>Stability Light Sensitive<br>Applications Perilla Ketone is an oil from Perilla frutescens which is very toxic as it is a potent pulmonary edemagenic agent for laboratory animals and livestock. This compound is commonly used in oriental foods.<br>References Wilson, B.J., et al.: Science, 197, 573 (1997)<br></p>Formula:C10H14O2Colore e forma:NeatPeso molecolare:166.22Olodaterol Hydrochloride
CAS:Prodotto controllato<p>Applications Olodaterol is a long acting β-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD).<br>References Cazzola, M., et al.: Pharmacol. Rev., 64, 450 (2012); Bouyssou, T., et al.: Bioorg. Med. Chem. Lett., 20, 1410 (2010);<br></p>Formula:C21H27ClN2O5Colore e forma:Off-White To Light BrownPeso molecolare:422.906β-Hydroxy Betamethasone
CAS:Prodotto controllato<p>Applications 6β-Hydroxy Betamethasone can be used as analyte in analytical study for detecting betamethasone metabolites in human urine using liquid chromatography coupled to tandem mass spectrometry.<br>References Matabosch, X., et al.: Drug Testing and Analysis, 7, 663-672 (2015)<br></p>Formula:C22H29FO6Colore e forma:NeatPeso molecolare:408.46DL-Indole-3-lactic Acid Methyl Ester-D5
CAS:Prodotto controllato<p>Applications DL-Indole-3-lactic Acid Methyl Ester-D5 is an intermediate used in the synthesis of DL-Indole-3-lactic Acid-d5 (I627102), which is the isotope labelled analog of DL-Indole-3-lactic Acid (I627100); a reagent in the synthesis of 2-hydroxy-1-(1H-indol-3-yl)-4-methylpentan-3-one which has weak antibacterial activity against 16 bacterial strains, including Escherichia coli, Bacillus subtilis and Staphylococcus aureus. DL-Indole-3-lactic Acid is also used in the preparation of Monatin, a natural sweet peptidomimetic.<br>References Nguyen, S.T., et al.: Bioorg. Med. Chem. Lett., 20, 5739 (2010); Nakamura, K., et al.: Peptide Sci., 40, 61 (2003)<br></p>Formula:C12D5H8NO3Colore e forma:NeatPeso molecolare:224.2677-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin
CAS:Prodotto controllato<p>Applications A major metabolite of Irinotecan.<br>References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),<br></p>Formula:C33H38N4O8Colore e forma:Light YellowPeso molecolare:618.6768tert-Butyl-d9 4-Nitrophenyl Carbonate
CAS:Prodotto controllato<p>Applications tert-Butyl-d9 4-Nitrophenyl Carbonate (cas# 1190006-35-9) is a compound useful in organic synthesis.<br></p>Formula:C112H9H4NO5Colore e forma:Off-WhitePeso molecolare:248.28Phosphoric Acid Tris(4-methylphenyl) Ester
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Phosphoric Acid Tris(4-methylphenyl) Ester is a human urinary organophosphate flame retardant metabolite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schindler, B., et al.: J. Chromat. B, 877, 375 (2009)<br></p>Formula:C21H21O4PColore e forma:Off-WhitePeso molecolare:368.362-Methyl Hippuric Acid-d2
CAS:Prodotto controllato<p>Applications The main labelled metabolite of o-xylene.<br>References Gregus, Z., et al.: Drug Metab. Dispos., 26, 1082 (1998), Gregus, Z., et al.: Xenobiotica, 29, 547 (1999), Gonzalez-Reche, L., et al.: Arch. Toxicol., 77, 80 (2003),<br></p>Formula:C10D2H9NO3Colore e forma:White To Off-WhitePeso molecolare:195.21Citric acid-2,4-13C2
CAS:Prodotto controllato<p>Applications Citric acid-2,4-13C2 is an isotopic analog of citric acid (C521000), a component of the Krebs cycle.<br></p>Formula:C2C4H8O7Colore e forma:White To Light YellowPeso molecolare:194.11Ouabain-d3 (Major)
CAS:Prodotto controllato<p>Applications Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);<br></p>Formula:C29H41D3O12Colore e forma:White To Off-WhitePeso molecolare:587.67Zinc Pentamethylenedithiocarbamate
CAS:<p>Applications Zinc pentamethylenedithiocarbamate (cas# 13878-54-1) is a useful research chemical.<br></p>Formula:C12H20N2S4ZnColore e forma:NeatPeso molecolare:385.94Lauric Acid-d3
CAS:Prodotto controllato<p>Applications Lauric Acid-d3, is the labeled analogue of Lauric Acid (L178550), a common saturated fatty acid found in nutmeg, palm kernel oil, coconut oil and butter fat.<br>References Liu, X. et al.: Int. J. Pharma., 443, 318 (2013);<br></p>Formula:C12D3H21O2Colore e forma:White To Off-WhitePeso molecolare:203.34N,N'-Methylene Ambroxol Hydrochloride
CAS:Prodotto controllato<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Formula:C14H18Br2N2O·ClHColore e forma:White To Off-WhitePeso molecolare:426.573,3'-Dithiobis(propionohydrazide)
CAS:Prodotto controllato<p>Applications 3,3'-dithiobis(propionohydrazide) (cas# 50906-77-9) is a useful research chemical.<br></p>Formula:C6H14N4O2S2Colore e forma:NeatPeso molecolare:238.335-Formyltetrahydropteroic Acid
CAS:Prodotto controllato<p>Impurity Calcium Folinate Hydrate EP Impurity E<br>Stability Unstable in Basic Solution<br>Applications 5-Formyltetrahydropteroic Acid is an impurity of Folic Acid (F680300); a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. It also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010); Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010); McKay, D., et al.: Nut. J., 9 (2010)<br></p>Formula:C15H16N6O4Colore e forma:NeatPeso molecolare:344.33Boc-L-aspartic Acid β-Methyl Ester
CAS:Prodotto controllato<p>Applications Boc-L-aspartic Acid β-Methyl Ester is used to prepare isoxazoline glycoprotein IIb/IIIa antagonists. It is also used to synthesize glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.<br>References Xue, C., et al.: J. Med. Chem., 40, 2064 (1997); Kirkland, T., et al.: Bioorg. Med. Chem., 16, 4963 (2008)<br></p>Formula:C10H17NO6Colore e forma:NeatPeso molecolare:247.245Isovaleryl L-Carnitine Chloride
CAS:Prodotto controllato<p>Applications Isovaleryl L-Carnitine Chloride is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.<br>References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)<br></p>Formula:C12H24ClNO4Colore e forma:NeatPeso molecolare:281.787-Nitrocoumarin
CAS:Prodotto controllato<p>Applications Coumarin derivatives were made for trial as bacteriostats.<br></p>Formula:C9H5NO4Colore e forma:NeatPeso molecolare:191.14Calcium Chloride Hydrate
CAS:<p>Applications Calcium Chloride Dihydrate is used in the preparation of bisphosphonates used in attacking cancer cells.<br>References Liu, D. et al.: Chem. Comm., 48, 2668 (2012);<br></p>Formula:Ca·2Cl·2H2OColore e forma:NeatPeso molecolare:147.011,3-Dimethylnaphthalene
CAS:Prodotto controllatoFormula:C12H12Colore e forma:ColourlessPeso molecolare:156.22N,N'-Bis[3-(trifluoromethyl-4-cyanophenyl]urea
CAS:Prodotto controllato<p>Applications N,N'-Bis[3-(trifluoromethyl-4-cyanophenyl]urea can be obtained from 5-Amino-2-cyanobenzotrifluoride (A603630) which can be used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.<br>References Xiao, H.-Y., et al.: Bioorg. Med. Chem. Lett., 20, 4491 (2010)<br></p>Formula:C17H8F6N4OColore e forma:NeatPeso molecolare:398.262Adenosine-5',5''-d2
CAS:Prodotto controllato<p>Applications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formula:C10H11D2N5O4Colore e forma:White SolidPeso molecolare:269.261,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester-d8
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester-d8 is labelled 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester (C987315) which is a possible metabolite of the di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) monoester (MINCH).<br>References Koch, H., et al.: Arch. Toxicol., 87, 799 (2013)<br></p>Formula:C17H20D8O6Colore e forma:NeatPeso molecolare:336.457-Hydroxy-1,3,6-naphthalenetrisulfonic Acid Trisodium
CAS:<p>Applications 7-Hydroxy-1,3,6-naphthalenetrisulfonic Acid is a pollutant that is found in waste water.<br>References Cristiano, N., et al.: Ind, Eng. Chem. Res., 46, 6674 (2007)<br></p>Formula:C10H5O10S3·3NaColore e forma:NeatPeso molecolare:450.30Beclomethasone 11,17,21-Tripropionate
CAS:Prodotto controllato<p>Impurity Beclomethasone Dipropionate EP Impurity S<br>Applications Beclomethasone 11,17,21-Tripropionate (Beclomethasone Dipropionate EP Impurity S) is an impurity of Beclomethasone (B131000), a glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).<br>References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),<br></p>Formula:C31H41ClO8Colore e forma:NeatPeso molecolare:577.11rac N-Bisdesmethyl Tramadol, Hydrochloride
CAS:<p>Applications A metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C14H22ClNO2Colore e forma:NeatPeso molecolare:271.78Methyl 1-Naphthaleneacetate
CAS:<p>Applications Methyl 1-naphthaleneacetate (cas# 2876-78-0) is a useful research chemical.<br></p>Formula:C13H12O2Colore e forma:NeatPeso molecolare:200.23cis-4-Hydroxycinnamic Acid
CAS:Prodotto controllato<p>Applications An antioxidative active compound isolated from the EtOAc layer of MeOH extracts of kochujang, Korean fermented red pepper paste. Photoisomerization of ionic liquid ammonium cinnamates. Cinnamic acids upon irradiation in solution undergo geometric isomerization while dimerizing to different dimers in the crystalline state.<br>References Armstrong, D., et al.: Anal. Chem., 73, 3679 (2001), Karmakar, B., et al.: J. Biotech., 80, 195 (2000),<br></p>Formula:C9H8O3Colore e forma:NeatPeso molecolare:164.16Ramipril-d5
CAS:Prodotto controllato<p>Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Formula:C23H27D5N2O5Colore e forma:WhitePeso molecolare:421.548-Thioguanosine
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 8-Thioguanosine (cas# 26001-38-7) is a useful research chemical.<br></p>Formula:C10H13N5O5SColore e forma:NeatPeso molecolare:315.3Pemetrexed acid
CAS:Prodotto controllatoFormula:C15H14N4O3Colore e forma:Off-WhitePeso molecolare:298.30Azelastine N-Oxide (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A metabolite of Azelastine (A808250).<br>References Heinemann, U. et al.: J. Chrom. B Anal. Tech. Biomed. Life Sci., 793, 389 (2003); Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979);<br></p>Formula:C22H24ClN3O2Colore e forma:NeatPeso molecolare:397.907-Methoxy-4-(trifluoromethyl)coumarin
CAS:Prodotto controllato<p>Applications 7-Methoxy-4-(trifluoromethyl)coumarin is a biochemical for proteomics research.<br></p>Formula:C8H8BrN3Colore e forma:White To Off-WhitePeso molecolare:226.0738-Amino-7-oxopelargonic Acid Hydrochloride
CAS:Prodotto controllato<p>Applications An intermediate in the synthesis of biotin. Pimeloyl-CoA is transformed into AOP in the presence of L-alanine by the enzyme AOP synthase. The catalytic mechanism of AOP synthase has been studied for the elucidation of inhibitors as potential antimicrobial agents.<br>References Ohsugi, M., et al.: J. Nutr. Sci. Vitaminol., 34 (4), 343 (1985), Pearson, B.M., et al.: Lett. Appl. Microbiol., 10 (2), 89 (1990), Ploux, O., et al.: Biochem. J., 283, 327 (1992)<br></p>Formula:C9H17NO3·ClHColore e forma:NeatPeso molecolare:223.701, N6-Etheno-2'-deoxyadenosine-13C5
Prodotto controllato<p>Applications 1, N6-Etheno-2’-deoxyadenosine-13C5 is caused by exposure to pollutants. It is an isotopically labeled analog of the 2’-Deoxyguanosine adduct.<br></p>Formula:C713C5H13N5O3Colore e forma:NeatPeso molecolare:280.23Guanosine 5'-Diphosphate Disodium Salt
CAS:Prodotto controllato<p>Applications Guanosine 5'-diphosphate disodium salt (cas# 7415-69-2) is a useful research chemical.<br></p>Formula:C10H13N5Na2O11P2Purezza:>85%Colore e forma:NeatPeso molecolare:487.16Denatonium Chloride
CAS:Prodotto controllato<p>Applications Denatonium Chloride is used to identify ligands for two human bitter T2R taste receptors.<br>References Pronin, A., et al.: Chem. Senses, 29, 583 (2004); Caicedo, A., et al.: Sci., 291, 1557 (2001);<br></p>Formula:C21H29ClN2OColore e forma:NeatPeso molecolare:360.92Iso Cytosine
CAS:Prodotto controllato<p>Applications A useful intermediate for chemical modifications of base and sugar moieties in natural nucleosides.<br>References Sashaki, T., et al.: J. Org. Chem., 40(1), 106 (1975)<br></p>Formula:C4H5N3OColore e forma:NeatPeso molecolare:111.10Cinnamic Acid
CAS:Prodotto controllato<p>Applications Cinnamic Acid is rac-form of trans-Cinnamic Acid (P336185) which is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids.<br>References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);<br></p>Formula:C9H8O2Colore e forma:White To Off-WhitePeso molecolare:148.1592-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid
CAS:Prodotto controllato<p>Applications 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid is a potential metabolite of Chlorthalidone.<br>References Salado C., et al.: J. Chromatography. Biomed. App., 690, 195 (1997);<br></p>Formula:C14H10ClNO5SColore e forma:NeatPeso molecolare:339.751,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid-d51
CAS:Prodotto controllato<p>Applications Isotope labelled 1,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid is a widely used and often incorporated in plasticizer for PVC for a higher molecular weight.<br>References Jones, C., et al.: Int. J. Artificial. Organs., 12, 466 (1989); Khang, G., et al.: Bio-Med. Mater. Engineer., 12, 135 (2002);<br></p>Formula:C33D51H3O6Colore e forma:NeatPeso molecolare:598.092Allo-3α-tetrahydro Cortisol
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A metabolite of Cortisol (H714615).<br>References Quinkler, M., et al.: J. Clin. Endocrinol. Metab., 88, 2384 (2003), Draper, N., et al.: J. Endocrinol., 186, 251 (2005), Kotlowska, A., et al.: Clin. Biochem., 42, 448 (2009),<br></p>Formula:C21H34O5Colore e forma:Off White SolidPeso molecolare:366.49N-Methylcytisine
CAS:<p>Applications N-Methylcytisine (cas# 486-86-2) is a compound useful in organic synthesis.<br></p>Formula:C12H16N2OColore e forma:Off-WhitePeso molecolare:204.272,3-Dibromoanthracene
CAS:Prodotto controllato<p>Applications 2,3-Dibromoanthracene is a useful synthetic intermediate. It is used to synthesize various acenes and acene derivatives such as Acenaphth[1,2-b]anthracene (A130745) which is mutagenic.<br>References Toyota, S., et al.: Sci. Syn., 45, 745 (2010); Durant, J., et al.: Mutat. Res-Genet. Tox., 371, 123 (1996)<br></p>Formula:C14H8Br2Colore e forma:NeatPeso molecolare:336.02Methyl-(4-nitrophenylethyl)-(4-nitrophenoxyethyl)amine
CAS:Prodotto controllato<p>Applications Methyl-(4-nitrophenylethyl)-(4-nitrophenoxyethyl)amine (cas# 115287-37-1) is a compound useful in organic synthesis.<br></p>Formula:C17H19N3O5Colore e forma:NeatPeso molecolare:345.35Acetyl-1,2-13C2 Coenzyme A Sodium Salt (~2% Unlabelled)
CAS:Prodotto controllato<p>Applications Acetyl-1,2-13C2 Coenzyme A Sodium Salt is a useful synthetic intermediate.<br></p>Formula:C2113C2H38N7O17P3S•x(Na)Colore e forma:NeatPeso molecolare:811.562299Dimethyl 2,7-Naphthalenedicarboxylate
CAS:Prodotto controllato<p>Applications Dimethyl 2,7-Naphthalenedicarboxylate (cas# 2549-47-5) is a useful research chemical.<br></p>Formula:C14H12O4Colore e forma:Off White To Light YellowPeso molecolare:244.2434’-Chloro-2-hydroxy-benzophenone
CAS:Prodotto controllato<p>Applications 4’-Chloro-2-hydroxy-benzophenone is a useful compound to investigate the effects of substituents on photo-antioxidant abilities of 2-hydroxybenzoyl compounds that can prevent autooxidation of plastics under UV light.4’-Chloro-2-hydroxy-benzophenone can also utilized to develop novel Azomethine Prodrugs of (R)-α-Methylhistamine.<br>References Dobashi, Y., et al.: Polym. Degrad. Stabil. 89, 140 (2005); Krause, M., et al.: J. Med. Chem. 38, 4070 (1995)<br></p>Formula:C13H9ClO2Colore e forma:NeatPeso molecolare:232.66D-(+)-Carvone
CAS:<p>Applications D-(+)-Carvone, is used for the synthesis of (-)-terpestacin, a fungal metabolite with anticancer activity.It is also found in the essential oils of the in vitro M. longifolia plantlets and callus, that can be used as a potential source of a safe flavouring agent.<br>References Jin , Y., et al.: Org. Biomol. Chem., 10(28), 5452 (12012); Morcia, C., et al.: Acta. Biochimica. Polonica., 58(4), 581 (2011);<br></p>Formula:C10H14OColore e forma:NeatPeso molecolare:150.22Petromyzonol 24-Sulfate Sodium Salt
CAS:Prodotto controllatoFormula:C24H41O7S·NaColore e forma:NeatPeso molecolare:496.63Docosanoic Acid Methyl Ester
CAS:<p>Applications Docosanoic Acid Methyl Ester is a long chain fatty acid, existing as a wax and is found in sunflower seeds. It can be used in biodiesel production.<br>References Soh, L. et al.: Green Chem., 13, 1422 (2011); Kanya, T.. et al.: Food Chem., 101, 1552 (2006);<br></p>Formula:C23H46O2Colore e forma:Off White SolidPeso molecolare:354.61Chlorosulfuric Acid Methyl Ester
CAS:Prodotto controllato<p>Stability Moisture Sensitive<br>Applications Chlorosulfuric Acid Methyl Ester is used in the synthesis of acetylenic TACE inhibitors in the treatment of arthritis.<br> E0<br>References Levin, J. et al.: Bioorg. Med. Chem. Lett., 15, 4345 (2005);<br></p>Formula:CH3ClO3SColore e forma:NeatPeso molecolare:130.554,4’-Bis(4”-aminobenzenesulfonyl) Diphenyl Ether Dihydrochloride
CAS:<p>Applications The diamino arylene disulfones used in polyamido polysulfone thermoplastics and intermediates.<br></p>Formula:C24H20N2O5S2•2HClColore e forma:NeatPeso molecolare:553.47Oxindole-3-acetic Acid-13C6
CAS:Prodotto controllato<p>Applications Oxindole-3-acetic Acid-13C6 is labelled derivative of Indoleacetic Acid (I577342) which has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase.<br>References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003)<br></p>Formula:C6C4H9NO3Colore e forma:NeatPeso molecolare:197.1392,6-Diiodo-4-nitrophenol
CAS:<p>Stability Light Sensitive<br>Applications 2,6-Diiodo-4-nitrophenol is useful for statistical methods for developing QSARs to predict toxicity of phenols to Tetrahymena pyriformis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cronin, M., et al.: Chemosphere, 49, 1201 (2002);<br></p>Formula:C6H3I2NO3Colore e forma:NeatPeso molecolare:390.91-(Chloromethyl)naphthalene
CAS:Prodotto controllato<p>Applications 1-(Chloromethyl)naphthalene is used in the identification of Novel p38α MAP Kinase Inhibitors. It is also used in the Identification of 1,5-Naphthyridine derivatives as a novel series of potent and selective TGF-β type I receptor inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gill, A., et al.: J. Med. Chem., 48, 414 (2005); Gellibert, F., et al.: J. Med. Chem., 47, 4494 (2004)<br></p>Formula:C11H9ClColore e forma:NeatPeso molecolare:176.64rac 3,4-Dihydroxymandelic Acid-d3
CAS:Prodotto controllato<p>Applications A labelled protein kinase C inhibitor.<br>References Marki, H.P., et al.: Helv. Chimica Acta, 71, 320 (1988), Iwagami, H., et al.: Bull. chem. Soc. Jpn., 63, 3073 (1990), Funahashi, T., et al.: J. Bacteriol., 184, 936 (2002),<br></p>Formula:C8H5D3O5Colore e forma:NeatPeso molecolare:187.163-(Difluoromethyl)-1H-pyrazole-4-carboxylic Acid
CAS:Prodotto controllato<p>References Zeun, R., et al.: Pest Manag. Sci., 69, 527 (2013); Oostendorp, M., et al.: Phytopathology, 101, S133 (2011); Olaya, G., et al.: Phytopathology, 101, S132 (2011)<br></p>Formula:C5H4F2N2O2Colore e forma:NeatPeso molecolare:162.09α-Hederin
CAS:<p>Stability Hygrscopic<br>Applications α-Hederin is a saponin of dry extracts from the leaves of Hedera helix L.Inhibitor of β2-adrenergic receptor-GFP fusion proteins. Potential cause for asphyxiation.<br>References Sieben A. et al.: Biochem., 21, 3477 (2009); Gaillard, Y. et al.: J. Anal Toxicol., 27, 257 (2003);<br></p>Formula:C41H66O12Colore e forma:NeatPeso molecolare:750.96Ibutilide Fumarate
CAS:Prodotto controllatoFormula:C20H36N2O3S·C4H4O4Colore e forma:NeatPeso molecolare:885.22Salicylic Acid-13C6
CAS:<p>Applications Labelled acetylsalicylic acid impurity B.<br>References Walter, M., et al.: Eur. J. Biochem., 1996, 239, 281 (1996), Bantignies, B., et al.: Plant Mol. Biol., 42, 871 (2000), Bais, H., et al.: J. Biol. Chem., 278, 32413 ( 2003), Finkler, C., et al.: Genetica, 124, 117 (2005),<br></p>Formula:C6CH6O3Colore e forma:NeatPeso molecolare:144.08Prasugrel Thiolactone-d5 (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications A labelled inactive metabolite of Prasugrel (P701150).<br>References Sugidachi, A., et al.: Br. J. Pharmacol., 129, 1439 (2000); Takahashi, S., et al.: J. Pharm. Sci., 97, 5434 (2008); Williams, E., et al.: Drug Metab. Dispos., 36, 1227 (2008); Hagihara, K., et al.: Xenobiotica, 39, 218 (2009);<br></p>Formula:C18H13D5FNO2SColore e forma:NeatPeso molecolare:336.435E-1-(2-Cyano-2-Hydroxyiminoacetyl)-3-Ethylurea
CAS:<p>Stability Moisture Sensitive<br>Applications E-1-(2-Cyano-2-hydroxyiminoacetyl)-3-ethylurea is an oxime containing compound that can be used as a reactant in the synthesis of Cymoxanil (C988995), which is a fungicide applied as seed treatment or as foliar application to the plants to control late blight.<br>References Greci, L., et al.: J. Chem. Res., Synop., 1, 655 (2003); Dhingani, J. C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Bakirici, G.T., et al.: Food. Chem., 135, 1901 (2012);<br></p>Formula:C6H8N4O3Colore e forma:NeatPeso molecolare:184.15Sodium Azide-15N3
CAS:<p>Applications Labelled Sodium Azide. Sodium azide is used in the preparation of 5-azidotetrazoles by reaction of (trifluoromethyl)azoalkanes with sodium azide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moller, C., et al.: Phys. Rev., 46, 618 (1934),<br></p>Formula:N3NaColore e forma:NeatPeso molecolare:67.99Dihydro Isoferulic Acid-d3 3-O-β-D-Glucuronide
CAS:Prodotto controllato<p>Applications Labelled Dihydroisoferulic Acid 3-O-β-D-Glucuronide, the glucuronide conjugate of Dihydroisoferulic Acid (H946365). Dihydroisoferulic Acid 3-O-β-D-Glucuronide is a minor circulating metabolite in human plasma after ingestion of coffee and can be used as a biomarker of coffee consumption.<br>References Fumeaux, R. et al.: Org. Biomol. Chem., 8, 5199 (2010); Stalmach, A. et al.: Drug Metab. Disp., 37, 1749 (2009);<br></p>Formula:C16H17D3O10Colore e forma:NeatPeso molecolare:375.344,4'-Di-tert-butyl-2,2'-bipyridine
CAS:Prodotto controllato<p>Applications 4,4'-Di-tert-butyl-2,2'-bipyridine acts as a reagent in the preparation, antiproliferative and cytotoxic activity of apoptotic ruthenium nitrogen heterocyclic complexes via combinatorial library synthesis.<br>References Mulcahy, S. P., et al.: Dalton Trans., 39, 177 (2010)<br></p>Formula:C18H24N2Colore e forma:NeatPeso molecolare:268.4Methyl Benzilate
CAS:Prodotto controllato<p>Applications Methyl Benzilate is a reactant in the synthesis of Trimethadione (T796155), an anticonvulsant and antiepileptic agent used in the treatment of pregnant women. Prenatal exposure to snti-epileptic drugs (AEDs) has indicated increased risk of major or minor congenital malformation.<br>References Pastore, V., et. al.: Bioorg. Med. Chem., 21, 841 (2013); Ahir, B. et al.: Toxicol. Vitro., 28, 948 (2014); Pastore, V. et al.: Bioorg. Med. Chem., 21, 841 (2013)<br></p>Formula:C15H14O3Colore e forma:Off White PowderPeso molecolare:242.27N6-Isopentenyladenosine
CAS:<p>Applications N6-Isopentenyladenosine has antiproliferative activity on MCF-7 breast cancer cells.<br>References Rajabi, M. et al.; DNA Cell Biol.; 29, 687 (2010)<br></p>Formula:C15H21N5O4Colore e forma:NeatPeso molecolare:335.364-tert-Butylacetophenone
CAS:Prodotto controllato<p>Applications 4-tert-Butylacetophenone is an impurity arising in the synthesis of Ebastine (E320000). Ebastine impurity B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C12H16OColore e forma:ColourlessPeso molecolare:176.25Psilocin-d4 (1 mg/mL in Acetonitrile)
CAS:Prodotto controllatoFormula:C12D4H12N2OColore e forma:ColourlessPeso molecolare:208.293'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt
CAS:Prodotto controllato<p>Applications A deuterated metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.This compounds contains Sodium Chloride. Water content not determined.<br></p>Formula:C16D3H17N5O10·NaColore e forma:NeatPeso molecolare:468.3658Mevastatin Hydroxy Acid Sodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood.<br>References Endo, A. et al.: Atheroscler. Supp., 5, 39 (2004); Hosobuchi, M. et al.: J. Ferm. Bioeng., 76, 470 (1993);<br></p>Formula:C23H35O6·NaColore e forma:NeatPeso molecolare:430.513-(4-Hydroxyphenyl)propionic Acid Methyl Ester
CAS:Prodotto controllato<p>Applications 3-(4-Hydroxyphenyl)propionic Acid Methyl Ester is a useful synthetic intermediate. It can be used to prepare potent and orally available G protein-coupled receptor 40 agonists as potential antidiabetic agents.<br>References Sasaki, S., et al.: J. Med. Chem., 54, 1365 (2011); Christiansen, E., et al.: ACS Med. Chem. Lett., 1, 345 (2010)<br></p>Formula:C10H12O3Colore e forma:NeatPeso molecolare:180.21-Nitropiperazine-d8
CAS:Prodotto controllato<p>Applications Labelled nitro substituted piperazine.<br></p>Formula:C4HD8N3O2Colore e forma:NeatPeso molecolare:139.183,3-Bis(2-hydroxyethyl)urea
CAS:Prodotto controllato<p>Applications 3,3-bis(2-hydroxyethyl)urea (cas# 23270-55-5) is a useful research chemical.<br></p>Formula:C5H12N2O3Colore e forma:NeatPeso molecolare:148.16Bisphenol A Bissulfate-d6 Disodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A labelled bisphenol derivative having antihemolytic activity.<br>References Morgan, B., et al.: Eur. J. Clin. Invest., 24, 219 (1994), Liszewski, M., et al.: Adv. Immunol., 61, 201 (1996), Assefa, H., et al.: Bioorg. Med. Chem. Lett., 9, 1889 (1999), Burdelev, O., et al.: Bioorg. Khim., 29, 159 (2003),<br></p>Formula:C15H8D6Na2O8S2Colore e forma:NeatPeso molecolare:438.41trans-α-Asarone
CAS:Prodotto controllatoFormula:C12H16O3Colore e forma:White To Off-WhitePeso molecolare:208.251,2-Diaminonaphthalene
CAS:Prodotto controllato<p>Applications Reacts with aldehydes to produce highly fluorescent imidazole derivatives. A fluorometric labeling reagent. It is used for fluorophotometric determination of selenium in some kinds of mushroom.<br>References Lehmann, S., et al.: J. Biol. Chem., 272, 21479 (1997), Ragg, E., et al.: Eur. J. Biochem., 266, 1192 (1999), Tagliavini, F., et al.: J. Mol. Biol., 300, 1309 (2000),<br></p>Formula:C10H10N2Colore e forma:NeatPeso molecolare:158.20Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Formula:C31H38ClN7O7S2•xH2OColore e forma:White To Off-WhitePeso molecolare:720.263-Hydroxyglutaric Acid-d5
CAS:Prodotto controllatoFormula:C5H3D5O5Colore e forma:NeatPeso molecolare:153.14
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