Standard farmaceutici
Gli standard farmaceutici sono un insieme completo di materiali di riferimento essenziali per garantire la sicurezza, l'efficacia e la qualità dei prodotti farmaceutici. Questa categoria include standard per ingredienti farmaceutici attivi (API), che sono i componenti principali responsabili degli effetti terapeutici. Inoltre, copre composti e metaboliti rilevanti sia per l'industria farmaceutica che veterinaria, fornendo punti di riferimento per la misurazione e l'analisi precisa di queste sostanze. Gli standard di controllo delle nitrosammine sono cruciali per rilevare e mitigare le nitrosammine potenzialmente dannose nelle formulazioni di farmaci. Gli standard di tossicologia aiutano a valutare la sicurezza e i potenziali effetti avversi dei composti farmaceutici. Inoltre, gli standard per attivatori e inibitori enzimatici sono vitali per la ricerca e lo sviluppo, consentendo studi precisi delle vie biochimiche e dei meccanismi d'azione dei farmaci. Questi standard farmaceutici sono strumenti indispensabili per la conformità normativa, il controllo di qualità e la ricerca, garantendo che i prodotti farmaceutici soddisfino rigorosi criteri di sicurezza ed efficacia.
Sottocategorie di "Standard farmaceutici"
- APIs per la ricerca e le impurità(273.647 prodotti)
- Attivatori e inibitori enzimatici(2.827 prodotti)
- Nitrosamine(2.605 prodotti)
- Composti e metaboliti farmaceutici e veterinari(2.602 prodotti)
- Tossicologia(13.652 prodotti)
Trovati 7836 prodotti di "Standard farmaceutici"
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Caffeidine Acid Sodium Salt
CAS:Prodotto controllato<p>Applications Caffeidine Acid is a potential degradation product from the hydrolysis of Caffeine (C080100) under alkaline environment.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>Formula:C8H11N4O3·NaColore e forma:NeatPeso molecolare:234.19Torsemide-d7
CAS:Prodotto controllato<p>Applications Labelled Torsemide (T548750). Used as a diuretic.<br>References Lesne, M., et al.: In. J. Clin. Pharmacol. Ther. Toxicol., 20, 382 (1982), Brater, D.C., et al.: Clin. Pharmacol. Ther., 42, 187 (1987),<br></p>Formula:C162H7H13N4O3SColore e forma:NeatPeso molecolare:355.46Prednisolone 21-β-D-Glucuronide
CAS:<p>Applications Prednisolone 21-β-D-Glucuronide Sodium Salt is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Formula:C27H35NaO11Colore e forma:NeatPeso molecolare:558.55Vitamin B2 (Riboflavin) 13C4 ,15N2
CAS:Prodotto controllatoFormula:C4C13H2015N2N2O6Colore e forma:NeatPeso molecolare:382.32Lumichrome
CAS:Prodotto controllato<p>Applications Lumichrome is a derivative of Riboflavin (R415000), a vitamin with a key role in maintaining cellular function and health in human and animals. Dyes and metabolites.<br>References Rajamani, S., et al.: Mol. Plant. Microbe. Interact., 21, 1184 (2008); Unna, K., et al.: J. Pharmacol. Exp. Ther., 76, 75 (1942), Rivlin, et al.: N. Engl. J. Med., 283, 463 (1970), Al-Shammary, F.J., et al.: Anal. Profiles Drug Subs., 19, 429 (1990),<br></p>Formula:C12H10N4O2Colore e forma:YellowPeso molecolare:242.23Surfactin
CAS:<p>Applications Surfactin is a lipopeptide antibiotic and biosurfactant.<br></p>Formula:C53H93N7O13Colore e forma:NeatPeso molecolare:1036.344-Nitrophenol-13C6
CAS:Prodotto controllato<p>Applications 4-Nitrophenol-13C6 is an intermediate in the synthesis of labelled 4-Aminophenol (A618920). It is also a nephrotoxic metabolite of Acetaminophen (A161220) and Phenacetin (P294580) (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Watanabe, et al.: Drug Metab. Dispos., 38, 1532 (2010)(2) Batuta, S. and Begum, N. A. Synth. Commun. 47, 137-147 (2017)<br></p>Formula:C6H5NO3Colore e forma:NeatPeso molecolare:145.0653,5-Diaminosalicylic Acid Dihydrochloride
CAS:Prodotto controllato<p>Impurity Mesalazine EP Impurity J (HCl)<br>Stability Hygroscopic<br>Applications 3,5-Diaminosalicylic acid Dihydrochloride, is the sulfate salt of 3,5-Diaminosalicylic acid. 3,5-Diaminosalicylic acid is an aromatic compound that belongs to a group of aminobenzoic acids (and derivatives) that can be used practically to prevent food spoilage and can treat animal protein aging.<br>References Ulrich, P., et al. Aminobenzoic Acids and Derivatives and Methods of Use for Preventing Protein Aging. US Patent 5514676. May 7 1996.<br></p>Formula:C7H8N2O3·2HClColore e forma:NeatPeso molecolare:168.1523646Ajmaline
CAS:Prodotto controllato<p>Applications An antiarrhythmic agent isolated from Rauwolfia serpentina.<br>References Galarreta, B., et al.: Bioorg. Med. Chem., 16, 6689 (2008), Sun, L., et al.: Plant Mol. Biol., 67, 455 (2008), Ruiz-May, E., et al.: Mol. Biotechnol., 41, 278 (2009),<br></p>Formula:C20H26N2O2Colore e forma:WhitePeso molecolare:326.43Chlorpheniramine-d6 Maleate Salt
CAS:Prodotto controllato<p>Applications Antihistaminic.<br>References Roth, F.E., et al.: J. Pharmacol. Exp. Ther., 124, 347 (1958), Smith, R.B., et al.: Toxicol. Appl. Pharmacol., 28, 240 (1974), Eckhart, C.G., et al.: Anal. Profiles Drug Subs., 7, 43 (1978)<br></p>Formula:C16D6H13ClN2·C4H4O4Colore e forma:WhitePeso molecolare:396.90N-Acetyl Sulfapyridine
CAS:Prodotto controllato<p>Applications A major active metabolite related to the adverse effects of Sulfasalazine in human serum.<br>References Stenson, W., et al.: J. Clin. Invest., 69, 494 (1982), Bissonnette, E., et al.: J. Immunol., 156, 218 (1996), Hirohata, S., et al.: J. Neurol. Sci., 67, 115 (1985), Pullar, T., et al.: Br. Med. J., 290, 1535 (1985), Ireland, A., et al.: Clin. Sci., 78, 119 (1990),<br></p>Formula:C13H13N3O3SColore e forma:NeatPeso molecolare:291.33rac 2-Isopropyl Pentanoic Acid
CAS:Prodotto controllato<p>Impurity Valproic Acid USP Related Compound B<br>Applications A constitutional isomer of Valproic acid; a potent anticonvulsant. Sodium valproate impurity C. Valproic Acid USP Related Compound B.<br>References Levy, R., et al.: Pharm. Res., 8, 551 (1991), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Fox, A., et al.: Pain, 105, 355 (2003), Archer, D., et al.: Anesth. Analg., 104, 180 (2007),<br></p>Formula:C8H16O2Colore e forma:Colourless To Light YellowPeso molecolare:144.215,8-Epoxy-13-cis Retinoic Acid(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications A metabolite of 13-cis-Retinoic Acid (R250000).<br>References Samokyszyn, V., et al.: J. Biol. Chem., 262, 14119 (1987), Oldfield, N., et al.: Drug Metabol. Dispos., 18, 1105 (1990), Samokyszyn, V., et al.: Chem. Res. Toxicol., 10, 795 (1997),<br></p>Formula:C20H28O3Colore e forma:NeatPeso molecolare:316.43Roflumilast N-Oxide
CAS:Prodotto controllato<p>Applications Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).<br>References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),<br></p>Formula:C17H14Cl2F2N2O4Colore e forma:NeatPeso molecolare:419.21Perindoprilat(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications Perindoprilat is an angiotensin-converting enzyme (ACE) inhibitor and antihypertensive.<br>References Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)<br></p>Formula:C17H28N2O5Colore e forma:NeatPeso molecolare:340.41Ramipril-d5
CAS:Prodotto controllato<p>Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Formula:C23H27D5N2O5Colore e forma:WhitePeso molecolare:421.54Glutaric Acid-1,5-13C2
CAS:<p>Applications Glutaric Acid-1,5-13C2 (cas# 1185108-16-0) is a compound useful in organic synthesis.<br></p>Formula:C313C2H8O4Colore e forma:NeatPeso molecolare:134.1Androstenediol 3-Acetate
CAS:Prodotto controllato<p>Applications Androstenediol 3-Acetate is an intermediate in the synthesis of Pregnenolone (P712200) which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Stastna, E., et al.: Steroids., 75, 721 (2010);<br></p>Formula:C21H32O3Colore e forma:NeatPeso molecolare:332.486β-Hydroxy Norethindrone Acetate
CAS:Prodotto controllato<p>Impurity Norethindrone Acetate EP Impurity F<br>Applications 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.<br>References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),<br></p>Formula:C22H28O4Colore e forma:Off-WhitePeso molecolare:356.46Mefruside
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Mefruside is a diuretic used for the treatment of edema and hypertension.<br>References Johansen, A., et al.: Euro. J. Epidemiol., 27, 63 (2012); Hasegawa, Y., et al.: Blood. Press. Supple., 1, 10 (2010);<br></p>Formula:C13H19ClN2O5S2Colore e forma:Off-WhitePeso molecolare:382.88Perilla Ketone
CAS:Prodotto controllato<p>Stability Light Sensitive<br>Applications Perilla Ketone is an oil from Perilla frutescens which is very toxic as it is a potent pulmonary edemagenic agent for laboratory animals and livestock. This compound is commonly used in oriental foods.<br>References Wilson, B.J., et al.: Science, 197, 573 (1997)<br></p>Formula:C10H14O2Colore e forma:NeatPeso molecolare:166.22(±)-trans-α-Bergamotene
CAS:Prodotto controllato<p>Applications (±)-trans-α-Bergamotene is an essential oil from medicinal plants of Cameroon.<br>References Boyom, F. F., et al.: Phytochem., 64, 1269 (2003);<br></p>Formula:C15H24Colore e forma:NeatPeso molecolare:204.3516α-Hydroxy Progesterone (>80%)
CAS:Prodotto controllatoFormula:C21H30O3Purezza:>80%Colore e forma:NeatPeso molecolare:330.46Terazosin-md
Prodotto controllato<p>Applications Terazosin-md is an analog of Terazosin (T105000) which is an α1-adrenergic receptor antagonist alleviating organ damage in studies done on rodent models of stroke and sepsis and has potential to be used for treatment for diseases.<br>References Chen, X., et al.: Nat. Chem. Biol, 11, 19 (2015)<br></p>Formula:C20H26N4O4Colore e forma:NeatPeso molecolare:386.4451,2,5,6-Tetramethylnaphthalene
CAS:Prodotto controllato<p>Applications 1,2,5,6-Tetramethylnaphthalene is a polycyclic aromatic hydrocarbon that has been found in petroleum.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Forster, P.G., et. al.: J. Chromatogr., 483, 384 (1989)<br></p>Formula:C14H16Colore e forma:NeatPeso molecolare:184.277N-(n-Butanesulfonyl)-O-[4-(4-pyridinyl)-butyl]-(S)-tyrosine
CAS:<p>Applications Tirofiban intermediate.<br></p>Formula:C22H30N2O5SColore e forma:NeatPeso molecolare:434.55β-Lapachone (>90%)
CAS:Prodotto controllato<p>Applications β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells.<br>References Renslo, A., et al.: Nat. Chem. Biol., 2, 701 (2006), Hopkins, A., et al.: Nat. Chem. Biol., 4, 682 (2008), Stuart, K., et al.: J. Clin. Invest., 118, 1301 (2008), Martin, R., et al.: Science, 25, 1680 (2009),<br></p>Formula:C15H14O3Purezza:>90%Colore e forma:Orange SolidPeso molecolare:242.27Melphalan
CAS:Prodotto controllato<p>Applications Melphalan is an antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980),<br></p>Formula:C13H18Cl2N2O2Colore e forma:NeatPeso molecolare:305.20Rosuvastatin Ethyl Ester
CAS:<p>Applications Rosuvastatin ethyl ester (CAS# 851443-04-4) is an intermediate formed during the synthetic preparation of rosuvastatin, a pharmaceutical used to manage LDL cholesterol.<br>References Sterk, D.; et al.: Tetrahedron Lett., 57, 1338 (2016); Olsson, A. G.; et al.: Am. Heart J., 144, 1044 (2002).<br></p>Formula:C24H32FN3O6SColore e forma:Off-White To Light BeigePeso molecolare:509.59(3’S)-ent-Ezetimibe
CAS:<p>Applications An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and cholesterol absorption inhibitor.<br></p>Formula:C24H21F2NO3Colore e forma:WhitePeso molecolare:409.43(+)-Citronellal
CAS:Prodotto controllato<p>Applications (+)-Citronellal is a monoterpene compound that is formed by the metabolism of plants. (+)-Citronellal is a natural insect repellant, and is the main component of citronellal oil. (+)-Citronellal is also used as a starting material in the one pot synthesis of (-)-Menthol (M218875).<br>References Kwon, Y., et al.: Curr. Biol., 20, 1672 (2010); Lenardão, E., et al.: Tetrahedron, 63, 6671 (2007); Milone, C., et al.: Appl. Catal. A-Gen., 199, 239 (2000)<br></p>Formula:C10H18OPurezza:>90%Colore e forma:NeatPeso molecolare:154.25Troglitazone Sulfate Ammonium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Troglitazone Sulfate is the major metabolite of Troglitazone (T892500), a hypoglycemic agent with cholestatic effect.<br>References Ciaraldi, T.P., et al.: Metabolism, 39, 1056 (1990); Kuzuya, T., et al.: Diabetes Res. Clin. Pract., 11, 147 (1991); Kellerer, M., et al.: Diabetes, 43, 447 (1994); Adachi, Y., et al.: Mol. Pharmacol., 67, 923 (2005);<br></p>Formula:C24H30N2O8S2Colore e forma:NeatPeso molecolare:538.636-Hydroxy Bromantane
CAS:Prodotto controllato<p>Applications 6-Hydroxy Bromantane is a metabolite of Bromantane (B678450).<br>References Bi, H., et al.: J. Steroid Biochem. Mol. Biol., 42, 229 (1992), Pozo, O., et al.: Anal. Bioanal. Chem., 389, 1209 (2007), Kiousi, P., et al.: Bioanalysis, 1, 1209 (2009),<br></p>Formula:C16H20BrNOColore e forma:NeatPeso molecolare:322.24Mycophenolic Acid Phenolic β-D-Glucoside
CAS:Prodotto controllatoFormula:C23H30O11Colore e forma:White To Off-WhitePeso molecolare:482.48Methyl Lithocholate
CAS:Prodotto controllato<p>Applications Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.<br>References Roleira, F.M., et al.: Lett. Drug. Design. Discovery., 7, 610 (2010);<br></p>Formula:C25H42O3Colore e forma:NeatPeso molecolare:390.60Ambrisentan
CAS:Prodotto controllato<p>Applications Nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Formula:C22H22N2O4Colore e forma:Off-WhitePeso molecolare:378.42N-Acetylthiourea
CAS:Prodotto controllato<p>Applications N-Acetylthiourea is a derivative of Thiourea (T375450); a compound used in biochemistry to increase the solubility (and resolution) of membrane proteins in two-dimensional electrophoresis. N-Acetylthiourea can be used as a reducing agent in a two-part self curing endodontic sealing system.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabbour, S.: Am. J. Clin. Dermatol., 4, 315 (2003); Himsworth, H.: Lancet, 242, 465 (1943); Rabilloud, T., et al.: Electrophoresis, 19, 758 (1998); Jin, S. et al. Self-curing system for endodontic sealant applications. PCT Int. Appl. WO 2009018464 A2 20090205. Feb 5, 2009<br></p>Formula:C3H6N2OSColore e forma:NeatPeso molecolare:118.16Bivalirudin α-ASPA 9 Analog Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Formula:C98H137N23O34•xC2HF3O2Colore e forma:NeatPeso molecolare:2181.271α-(Chloromethyl) Chlormadinone Acetate
CAS:Prodotto controllato<p>(1α)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)-pregna-4,6-<br>diene-3,20-dione; 6-Chloro-1α-(chloromethyl)-17-<br>hydroxypregna-4,6-diene-3,20-dione Acetate; Cyproterone<br>Acetate EP Impurity C</p>Formula:C24H30Cl2O4Colore e forma:NeatPeso molecolare:453.40Muraglitazar
CAS:Prodotto controllato<p>Applications It is a peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist.<br>References Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 6, 427 (2005), Devasthale, P.V., et al.: J. Med. Chem., 48, 2248 (2005), Kendall, D.M., et al.: Diabetes care, 29, 1016 (2006),<br></p>Formula:C29H28N2O7Colore e forma:NeatPeso molecolare:516.54γ-Butyrobetaine-d9
CAS:Prodotto controllato<p>Applications γ-Butyrobetaine-d9 is the labelled analogue of γ-Butyrobetaine, a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).<br>References Enomoto, A. et al.: J. Biol. Chem., 277, 36262 (2002)<br></p>Formula:C72H9H7NO2Colore e forma:NeatPeso molecolare:155.26Imipenem, Monohydrate
CAS:Prodotto controllatoFormula:C12H17N3O4S·H2OColore e forma:White To Light YellowPeso molecolare:317.36Diazoxide-d3
CAS:Prodotto controllato<p>Applications Diazoxide-d3 is the labeled analogue of Diazoxide (D417305), which reduces status epilepticus neuron damage in diabetes.<br>References Baba, A., et al.: J. Neurosci., 23, 7737 (2003); Bancila, V., et al.: J. Neurochem., 90, 1243 (2004); Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005)<br></p>Formula:C8H4D3ClN2O2SColore e forma:NeatPeso molecolare:233.69Bromantane
CAS:Prodotto controllato<p>Applications Bromantane is an adamantane derivative used as an anxiolytic agent.<br>References Reznikov, A., et al.: Endokrinologie, 73, 11 (1979), Grekhova, T., et al.: Bull. Eksp. Biol. Med., 119, 302 (1995),<br></p>Formula:C16H20BrNColore e forma:White To Off-WhitePeso molecolare:306.24Desacetyl Diltiazem
CAS:<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Formula:C20H24N2O3SColore e forma:White To BrownPeso molecolare:372.48Petromyzonol 24-Sulfate Sodium Salt
CAS:Prodotto controllatoFormula:C24H41O7S·NaColore e forma:NeatPeso molecolare:496.63trans-α-Asarone
CAS:Prodotto controllatoFormula:C12H16O3Colore e forma:White To Off-WhitePeso molecolare:208.25Bromfenac Sodium Sesquihydrate
CAS:Prodotto controllato<p>Applications Bromfenac is a non-steroidal anti-inflammatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), MacDonald, J., et al.: Toxicol. Sci., 110, 40 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Formula:C15H11BrNO3·2Na·3H2OColore e forma:Light YellowPeso molecolare:766.342,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5
CAS:Prodotto controllato<p>Applications 2,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5 is the isotope labelled analog of 2,3,4-Trihydroxybenzophenone; a trihydroxy derivative of Benzophenone (B204980) which is a compound used in the manufacturing of antihistamines, hypnotics, and insecticides.<br>References Wallace, W., et al.: Environ. Toxicol. Chem., 19, 962 (2000); Hayashi, T., et al.: Toxicol. Lett., 167, 1 (2006); Bechard, K., et al.: Aquat. Toxicol., 90, 310 (2008)<br></p>Formula:C13D5H5O4Colore e forma:NeatPeso molecolare:235.247
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