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Standard farmaceutici

Standard farmaceutici

Gli standard farmaceutici sono un insieme completo di materiali di riferimento essenziali per garantire la sicurezza, l'efficacia e la qualità dei prodotti farmaceutici. Questa categoria include standard per ingredienti farmaceutici attivi (API), che sono i componenti principali responsabili degli effetti terapeutici. Inoltre, copre composti e metaboliti rilevanti sia per l'industria farmaceutica che veterinaria, fornendo punti di riferimento per la misurazione e l'analisi precisa di queste sostanze. Gli standard di controllo delle nitrosammine sono cruciali per rilevare e mitigare le nitrosammine potenzialmente dannose nelle formulazioni di farmaci. Gli standard di tossicologia aiutano a valutare la sicurezza e i potenziali effetti avversi dei composti farmaceutici. Inoltre, gli standard per attivatori e inibitori enzimatici sono vitali per la ricerca e lo sviluppo, consentendo studi precisi delle vie biochimiche e dei meccanismi d'azione dei farmaci. Questi standard farmaceutici sono strumenti indispensabili per la conformità normativa, il controllo di qualità e la ricerca, garantendo che i prodotti farmaceutici soddisfino rigorosi criteri di sicurezza ed efficacia.

Sottocategorie di "Standard farmaceutici"

Trovati 8108 prodotti di "Standard farmaceutici"

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  • (S)-3',5'-Bis(trifluoromethyl)-1-phenethanol

    CAS:

    (S)-3',5'-Bis(trifluoromethyl)-1-phenethanol is a choline derivative that is used in the treatment of liver cancer. It has been shown to increase the permeability of cell membranes and to suppress the growth of tumor cells by inhibiting protein synthesis. (S)-3',5'-Bis(trifluoromethyl)-1-phenethanol can be used as a surfactant and a hydrophobic solvent for optimization of reaction parameters. This chemical also has been shown to be active against Gram-positive bacteria such as Staphylococcus aureus and Enterococcus faecalis, but not against Gram-negative bacteria such as Escherichia coli or Pseudomonas aeruginosa. The mechanism of this effect is mediated by chloride ions that act as bioreductive agents on cellular membranes, leading to increased permeability and cell death.

    Formula:C10H8F6O
    Purezza:Min. 95%
    Peso molecolare:258.16 g/mol

    Ref: 3D-FB18756

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  • 5'-Amino-5'-deoxy-2',3'-O-(1-methylethylidene)-adenosine

    CAS:

    Please enquire for more information about 5'-Amino-5'-deoxy-2',3'-O-(1-methylethylidene)-adenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C13H18N6O3
    Purezza:Min. 95%
    Peso molecolare:306.32 g/mol

    Ref: 3D-FA143512

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  • (6S)-5,6,7,8-Tetrahydro-6-(propylamino)-1-naphthalenol

    Prodotto controllato
    CAS:

    Rotigotine is a drug that is used to treat Parkinson's disease. It is a dopamine agonist that stimulates the release of dopamine in the brain. Rotigotine has been shown to be effective in controlling symptoms of Parkinson's disease, such as tremors and stiffness, and improving motor skills. This drug has also been shown to have a good tolerability profile, with few side effects reported. Rotigotine is rapidly absorbed from the gastrointestinal tract and metabolized by CYP2D6 into desalkyl rotigotine, which are pharmacologically inactive compounds. The mean terminal half-life for rotigotine is about 2 hours.

    Formula:C13H19NO
    Purezza:Min. 95%
    Peso molecolare:205.3 g/mol

    Ref: 3D-FT28115

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  • 2,4,4’-Trichlorobiphenyl

    Prodotto controllato
    CAS:

    2,4,4’-Trichlorobiphenyl is a polychlorinated biphenyl congener. It has been shown to have an adverse effect on the central nervous system, causing neurotoxicity. 2,4,4’-Trichlorobiphenyl has been used as a model system for the study of the effects of environmental toxins on mitochondrial membrane potential and lipid peroxidation. 2,4,4’-Trichlorobiphenyl binds to fatty acids in mitochondria and inhibits fatty acid β-oxidation. The inhibition of fatty acid oxidation leads to increased levels of protocatechuic acid in the serum and liver tissue. 2,4,4’-Trichlorobiphenyl has also been found to be toxic to aquatic organisms such as fish and shrimp at low concentrations.

    Formula:C12H7Cl3
    Purezza:Min. 95%
    Peso molecolare:257.54 g/mol

    Ref: 3D-FT170755

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  • 7-Amino-4-(trifluoromethyl)coumarin

    CAS:

    7-Amino-4-(trifluoromethyl)coumarin is a coumarin derivative that has been used as a fluorescence probe for the study of enzyme activities. It can be used as a potential biomarker for autoimmune diseases, and has also been shown to have tyrosine kinase domain binding activity. 7-Amino-4-(trifluoromethyl)coumarin can bind to the hydroxyl group in tyrosine residues with high affinity, and binds to the nitrogen atoms in protein kinases with low affinity. This compound is able to form intermolecular hydrogen bonds and steric interactions with peptide hormones.

    Formula:C10H6F3NO2
    Purezza:Min. 95%
    Peso molecolare:229.16 g/mol

    Ref: 3D-FA74300

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  • D,L-Threo-b-hydroxy aspartic acid

    CAS:

    D,L-Threo-b-hydroxy aspartic acid is a stereoselective synthetic amino acid that has been used to study the uptake and hydrolysis of D,L-threo-b-hydroxy aspartic acid by rat brain synaptosomes. It has also been used in the synthesis of an L-alanine analogue with the same stereochemistry at the chiral center. The stereoselective synthesis of this compound is achieved by epimerization reaction using d-alanine as a starting material. Threo bhda has been shown to inhibit glutamate release from neurons and stimulate GABA release in synaptosomes, which may be due to its ability to bind to ion channels. Threo bhda has also been found to inhibit the binding of radioactive thymidine to calf thymus DNA with a high degree of stereoselectivity.

    Formula:C4H7NO5
    Purezza:Min. 95%
    Peso molecolare:149.1 g/mol

    Ref: 3D-FT28259

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  • (±)-3-Methyl-2-oxovaleric acid

    CAS:

    (±)-3-Methyl-2-oxovaleric acid is a fatty acid that is found in the mitochondria of liver cells and other tissues. It is an intermediate in the citric acid cycle and can be converted into acetyl-CoA, which is used for energy production. (±)-3-Methyl-2-oxovaleric acid has been shown to cause necrotic cell death when it binds to the mitochondrial membrane potential and causes a loss of ATP production. This results in a lack of energy for the cell, leading to cell death. (±)-3-Methyl-2-oxovaleric acid has also been shown to inhibit protein synthesis by decreasing uptake and increasing creatine kinase activity. This inhibition leads to decreased body formation and tissue culture growth in vitro. In vivo, (±)-3-Methyl-2-oxovaleric acid causes primary sclerosing cholangitis, a disease characterized by inflammation of bile ducts that

    Formula:C6H10O3
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:130.14 g/mol

    Ref: 3D-FM157432

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  • a,O-Dimethyl serotonin

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    CAS:

    a,O-Dimethyl serotonin is a monoamine compound that is synthesized by the enzymatic decarboxylation of 5-hydroxytryptophan. It has been shown to increase dopamine levels and inhibit the enzyme activity of serotonin in mice. This drug also binds to 5-ht2 receptors and induces the release of serotonin from nerve cells. A linear calibration curve was obtained using bufotenin as a standard. This drug has been used in analytical toxicology for determining the uptake of serotonin into human lung tissue and its effect on 5-ht1a receptors. In addition, a study was conducted with perennial ryegrass to determine whether this drug inhibits plant toxin synthesis. The results showed that it did not have an inhibitory effect on plant toxins and may even promote their synthesis.

    Formula:C12H16N2O
    Purezza:Min. 95%
    Peso molecolare:204.27 g/mol

    Ref: 3D-FD22257

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  • Proflavine hemisulfate

    CAS:

    Proflavine hemisulfate is an antibiotic that inhibits bacterial growth by binding to DNA and inhibiting DNA synthesis. It binds to the dinucleotide phosphate of the bacterial ribosome and changes the shape of the nucleotide, preventing attachment of amino acids to form proteins. Proflavine hemisulfate also has a strong affinity for nuclear dna and is bound to it in a form that inhibits replication. The free form of proflavine is converted into enzyme form by phosphorylation, which inhibits protein synthesis and cell division. Proflavine hemisulfate has been shown to inhibit multidrug efflux pumps in bacteria, leading to increased susceptibility of bacteria to antibiotics. In addition, proflavine hemisulfate possesses inhibitory properties against transfer reactions in cells. The method used for measuring proflavine hemisulfate activity is electrochemical impedance spectroscopy (EIS) on cell nuclei suspensions in a model system.

    Formula:C13H11N3•(H2SO4)0•(H2O)x
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:258.29 g/mol

    Ref: 3D-FP01535

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  • cis-trans Nepetalactone

    CAS:

    荆芥内酯是一种驱虫的化合物,使猫薄荷开花植物能够吸引猫。据信,荆芥内酯可以通过模仿猫的信息素来改变猫的行为。

    Formula:C10H14O2
    Purezza:Min. 97 Area-%
    Colore e forma:Colorless Clear Liquid
    Peso molecolare:166.22 g/mol

    Ref: 3D-FN74295

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  • 17-Hydroxy-19-nor-17alpha-pregna-4,6-dien-20-yn-3-one acetate

    CAS:

    Please enquire for more information about 17-Hydroxy-19-nor-17alpha-pregna-4,6-dien-20-yn-3-one acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C22H26O3
    Purezza:Min. 95%
    Colore e forma:Off-white to pale yellowsolid.
    Peso molecolare:338.44 g/mol

    Ref: 3D-FH20928

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  • 2'-Acetylacteoside

    CAS:

    2'-Acetylacteoside is a naturally occurring phenylethanoid glycoside, which is derived from various plant sources. It exhibits antioxidant properties by scavenging reactive oxygen species and inhibiting oxidative stress. This mode of action supports cellular health by protecting cells from oxidative damage and maintaining redox balance.

    Purezza:Min. 95%

    Ref: 3D-FA74397

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  • Tetramethylurea

    CAS:

    Tetramethylurea is a versatile compound that has various applications in different fields. It is commonly used as a monophosphate donor in biochemical reactions and as a reagent for the synthesis of L-sorbose and histidine. In addition, tetramethylurea is employed in the production of herbicides, as well as in the synthesis of zirconium oxide nanoparticles.

    Formula:C5H12N2O
    Purezza:Min. 95%
    Peso molecolare:116.16 g/mol

    Ref: 3D-FT32584

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  • (+)-B-Chlorodiisopinocampheylborane - 60-65% in Hexane

    CAS:
    (+)-B-Chlorodiisopinocampheylborane is a chiral organoboron reagent that can be used for the enantioselective synthesis of amines. It is prepared from the reaction of chlorodiphenyl borane with (+)-diaminobenzene in hexane. The product can be purified by column chromatography or recrystallization. (+)-B-Chlorodiisopinocampheylborane can also be used in the synthesis of other compounds, such as pyrroles and pantolactones. It is an excellent catalyst for the dehydration of primary amines to give unsymmetrical ketones. This reagent has been shown to be effective in asymmetric hydrogenation reactions, such as the reduction of chiral secondary alcohols, and is also capable of catalyzing aldol reactions.
    Formula:C20H34BCl
    Purezza:Min. 95%
    Colore e forma:Clear Liquid
    Peso molecolare:320.75 g/mol

    Ref: 3D-FC59961

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  • 3a-Hydroxy tibolone

    Prodotto controllato
    CAS:

    Tibolone is a synthetic hormone that is used in the treatment of menopausal symptoms and breast cancer. Tibolone has been shown to be an effective treatment for menopausal symptoms, such as hot flashes and vaginal dryness, by providing relief from these symptoms. Tibolone has also been shown to have anti-cancer effects. This drug may be useful for treating breast cancer because it can inhibit the growth of cancer cells by binding to estrogen receptors and blocking estrogen-induced cell proliferation. Tibolone also stimulates angiogenesis, which is the formation of new blood vessels in order to provide nutrients and oxygen to growing tissue. It has been shown that this drug inhibits the synthesis of hepg2 cells in vitro, which are involved in the production of angiogenic factors. Tibolone may also have clinical relevance as a chemopreventive agent against prostate cancer.BR> Tibolone has also been shown to stimulate sulphatase activity in vitro, which may contribute to

    Formula:C21H30O2
    Purezza:Min. 95%
    Peso molecolare:314.46 g/mol

    Ref: 3D-FH24140

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  • (1'S,2'S)-Nicotine 1'-oxide

    CAS:

    Nicotine 1'-oxide is a metabolite of nicotine which is a naturally occurring alkaloid. Nicotine 1'-oxide is produced by the oxidation of nicotine and can be found in tobacco smoke, as well as in the urine of humans. Nicotine 1'-oxide has been shown to have enzyme inhibiting properties, and has been shown to decrease insulin-stimulated glucose transport rate in human liver cells. This product also has potential use as a stabilizer for pharmaceuticals or other organic substances, and can inhibit demethylation reactions that may lead to carcinogenesis. Nicotine 1'-oxide may also play a role in the transport of chemicals across membranes.

    Formula:C10H14N2O
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:178.23 g/mol

    Ref: 3D-FN26201

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  • 2,2’,3,3’,4,4’,5,5’,6-Nonabromobiphenyl

    Prodotto controllato
    CAS:

    Please enquire for more information about 2,2’,3,3’,4,4’,5,5’,6-Nonabromobiphenyl including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C12HBr9
    Purezza:Min. 95%
    Peso molecolare:864.27 g/mol

    Ref: 3D-FN165606

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  • (NZ)-4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]piperidin-2-ylidene]benzenesulfonamide

    Prodotto controllato
    CAS:

    Please enquire for more information about (NZ)-4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]piperidin-2-ylidene]benzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C19H20ClN3O4S
    Purezza:Min. 95%
    Peso molecolare:421.9 g/mol

    Ref: 3D-FN154024

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  • Amoxicillin trihydrate impurity B

    CAS:

    Amoxicillin trihydrate impurity B is an impurity of amoxicillin trihydrate, a penicillin antibiotic. Impurities are substances that are not intentionally added to the drug and may be formed during the manufacturing process. Impurities can affect the quality and safety of drugs, although their presence does not necessarily indicate a problem with the drug. Impurities in amoxicillin trihydrate include clavulanate potassium (impurity A) and heptane-2-carboxylic acid (impurity C). Impurity A is present in small quantities, typically less than 1% of the total amount of amoxicillin trihydrate. Impurity C is present in larger quantities and can make up to 10% of the total amount of amoxicillin trihydrate.

    Formula:C16H19N3O5S
    Purezza:Min. 95%
    Peso molecolare:365.41 g/mol

    Ref: 3D-FA63616

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  • N-Acetyl-L-leucyl-L-leucyl-L-methioninal

    CAS:
    Inhibitor of cathepsin
    Formula:C19H35N3O4S
    Purezza:Min. 95%
    Peso molecolare:401.57 g/mol

    Ref: 3D-FA137466

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