Glicoscienza

<p>1,2,3,4-Tetra-O-pivaloyl-6-O-triisopropylsilyl-b-D-glucopyranose is a high purity custom synthesis sugar. It has been modified with fluorination and glycosylation. The CAS number for this product is 8071-79-8. Synthetic modification of the sugar to form an oligosaccharide or monosaccharide can also be performed. This product is a complex carbohydrate that contains saccharides in the form of a sugar molecule linked together by glycosidic bonds.</p>

<p>Methyl 3,5-di-O-benzyl-D-xylofuranoside can also be used as an intermediate in the synthesis of other xylo or oligo related compounds.</p>

<p>2,4-Dihydroxy-2-hydromethylbutanoic acid-1,4-lactone is a hydroxy anion that can be synthesized by the lactonization of 2,4-dihydroxybutanoic acid. The compound has been used to produce polymeric adsorbents for chromatographic purposes.</p>

<p>Benzyl-2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-a-D-glucopyranoside is an acetamido sugar molecule that has been synthesized by the reaction of benzyl alcohol with a glucoside. This compound has been shown to have potential antihistamine and anticancer activities, as well as being a potential building block for the synthesis of nucleosides. The benzyl group in this sugar molecule is vicinal and the hydroxyl groups are anilines. The conformation of this molecule is determined by lysine and arginine residues on the 3' end of the sugar chain. In order to synthesize this compound, anhydrous DMSO was used as a solvent. This chemical's properties were measured using NMR spectroscopy.</p>

<p>Methyl 2,4-di-O-methyl-α-D-glucopyranoside is a selectively protected glucose glycoside</p>

<p>Man-9 N-glycan is a glycoprotein that is found on the surface of many viruses. It has an oligosaccharide structure, which consists of a mannose and a glucose molecule linked by an alpha-1,3-glycosidic bond. The Man-9 N-glycan can be found in human serum and is involved in lectin binding to cells. It also has antiviral activity and may be used as a model system for studying glycosidic bonds. This glycan can be broken down into smaller components by methyl glycosides or titration calorimetry, which is a technique for determining the molecular weight of substances. The Man-9 N-Glycan binds to toll-like receptor 2 (TLR2) on the surface of human cells, which activates an antibody response.</p>

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a synthetic, fluorinated monosaccharide that belongs to the group of oligosaccharides. It is used in the synthesis of complex carbohydrates. Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a custom synthesis and can be modified with methylation or click chemistry. Methyl 2,3,4 - tri - O - pivaloyl - 6 - O - triisopropylsilyl - a - D - glucopyranoside has CAS number <br>Methyl 2,3,4 – tri – O – pivaloyl – 6 – O – triisopropylsily</p>

<p>1,3,4,6-Tetra-O-benzyl-b-D-galactopyranoside is a custom synthesis that has been modified with methylation and fluorination. It is an oligosaccharide composed of saccharides linked by glycosidic bonds. Carbohydrates are polymers of monosaccharides, which can be classified as either simple sugars or complex carbohydrates. This product is a high purity, synthetic sugar that is suitable for use in the synthesis of complex carbohydrate polymers.</p>

<p>Click reagent for metabolic labeling of GlcNAc</p>

<p>Inhibitor of alpha-glucosidase</p>

<p>The blood group B type III/IV linear trisaccharide is a synthetic oligosaccharide. The methylation of the saccharide and click modification of the polysaccharide molecule allow for fast, efficient synthesis. This product has been custom synthesized to be free of impurities, high in purity, and available in glycosylation form. It can be modified with fluorination or other modifications to meet your needs.</p>

<p>Human milk oligosaccharide; attenuates inflammatory cytokine release</p>

<p>PolyGlycopleX (PGX) is produced from a mixture containing proprietary proportions of three polysaccharides, konjac glucomannan, xanthan gum and sodium alginate.  Recent hydrodynamic, rheological and analytical studies have shown that the unexpectedly high viscosity of solutions of PGX is consistent with an interaction between a konjac glucomannan, xanthan gum complex and sodium alginate to form a new, ternary complex in solution. Human and animal feeding studies have shown that PGX can be used to control weight, lower the glycaemic index of foods and postprandial glycaemia.</p>

<p>Phenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a custom synthesis of the sugar phenyl 2-acetamido-3,4,6-tri-O-acetyl--2 deoxy--b D glucopyranoside. It is a modification of the monosaccharide and glycosylation. This synthetic compound has a CAS number of 1308921 9 and is used as an intermediate in the production of saccharides. Phenyl 2 acetamido 3,4,6 tri O acetyl 2 deoxy b D glucopyranoside is also classified as an oligosaccharide or complex carbohydrate.</p>

<p>(2S, 3S, 4R) -2- [(1R) - 1, 2-Dihydroxyethyl] -3, 4- pyrrolidinediol is a benzyl-containing compound that is used as a glycoside hydrolase inhibitor. It has been shown to be an effective treatment for inflammatory bowel disease. This drug binds to the active site of glycosidases and blocks the hydrolysis of c-glycosides in the intestine. (2S, 3S, 4R) -2- [(1R) - 1, 2-Dihydroxyethyl] -3, 4- pyrrolidinediol also inhibits chloride channels and has been shown to have antiinflammatory properties.</p>

<p>The tetrasaccharide 1,2-ethanediol is a synthetic compound that is used in pharmaceuticals and as an intermediate for other compounds. This product is a high purity custom synthesis that can be used for methylation or glycosylation reactions. The CAS number for this product is 615-86-1.</p>

<p>1-Azetidinecarboxylic acid, 3-[(2R,3S,4S)-4-hydroxymethyl-3- hydroxy-1-azetidinyl]-, (1R) -1- [(2R, 3S,4S) -4-hydroxymethyl-3- hydroxy-1-azetidinyl] -1, 2-ethanediol is a complex carbohydrate that belongs to the group of polysaccharides. It has been modified by methylation and glycosylation. This product has high purity and is fluorinated for solubility.</p>

<p>1,3,5-Tri-O-benzoyl-2-deoxy-2-bromo-alpha-L-arabinofuranose is a complex monosaccharide that can be used as a building block in the synthesis of various compounds. It is a derivative of the sugar arabinose, with the addition of benzoyl and bromo groups at specific positions. The compound has potential applications in the fields of organic chemistry and medicinal chemistry and is available for research.</p>

<p>Chitosan is the deacetylated form of chitin.  The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid).  This then allows the material to be used in a number of industrial applications as a binder and film former.</p>

<p>N-Methyl-D-glucamine HCl is a salt of N-methylglucamine and hydrochloric acid. It is used as a buffer to maintain the pH of solutions at a desired level. N-Methyl-D-glucamine HCl has an inhibition constant (Ki) of 0.5 mM for glutamate, which can be used to measure the concentration of glutamate in tissue samples or reaction mixtures. This compound also inhibits locomotor activity, and its effect on blood pressure may be due to its ability to inhibit amines. The Ki for chloride is approximately 2 mM, and it can be used to measure the concentration of chloride in solution.</p>

<p>Trehalose is a naturally occurring disaccharide found in many organisms. Its role in nature is as versatile as its applications in the laboratory. Trehalose is synthesised by cells in response to stress and helps retaining the cellular integrity under tough conditions. An important function of trehalose is to stabilise protein structures and to prevent proteins from their degradation. Researchers use trehalose for instance as a carbon source in selective microbiological media, as desiccation protectant and for cryoprotection.</p>

<p>Produced from starch; white hygroscopic spray-dried powder; easily digestible</p>

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.</p>

<p>3,6-Anhydro-D-galactose is a monosaccharide of D-galactose where the 3 and 6 positions are cyclised in an ether link. 3,6-Anhydro-D-galactose is found naturally occurring in Rhodophyta (Red Algae) and is a constituent of the sulphated polysaccharide PLS, which has shown anti-inflammation activity and anti-nociceptive effects. In addition, sulphated polysaccharide is capable of inhibiting the in vitro replication of Herpes simplex virus type 1 (HSV-1) and HIV-1.<br>Our 10% aqueous solution is a 10% wt/wt solution of 3,6-Anhydro-D-galactose in water. 10 mg MA07897 contains 1 mg 3,6-Anhydro-D-galactose.<br>We also offer the same product in a non-aqueous solution, MA05223.</p>

<p>Important resource for RNA- and DNA-related syntheses including ribosylation</p>

<p>3'-Sialyllacto-N-neotetraose sodium is a synthetic, fluorinated oligosaccharide with a sialic acid side chain. This compound has been shown to be an inhibitor of lacto-N-neotetraose synthesis in the human gut. It is also used as a raw material for the synthesis of various complex carbohydrates and as a click modification reagent for saccharides and polysaccharides. 3'-Sialyllacto-N-neotetraose sodium can be modified at its methyl group or sugar moiety to produce desired products.</p>

<p>Food additive, applied in pharmaceuticals and beauty products.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>NGA1F N-Glycan is a custom synthesis, modification, fluorination, methylation, monosaccharide, synthetic glycan with a CAS No. that has been modified by the click chemistry reaction. It is an oligosaccharide that is saccharide and polysaccharide that has been glycosylated with sugar and carbohydrate.</p>

<p>2-Acetamido-6-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is an n-acetylated disaccharide (naturally occurring) that is a glycosidic bond between the two sugars, n-acetyl D galactosamine and 2,3,4,6 tetraacetamido 2 deoxy D galactose. This compound has an acetamide residue in place of a hydroxyl group on the second carbon atom of the sugar. The linkage between these two sugars is a glycosidic bond. In its natural form, this molecule can be found in mammalian cells and bacterial cell walls.</p>

<p>1-Deoxy-2,3:4,5:6,7-Tris-O-(1-methylethylidene)-D-glycero-D-guloheptitol is a high purity custom synthesis sugar that can be modified with fluorination and glycosylation. This product is synthesized from monosaccharides and saccharides. It has the CAS No. 1801528-80-2 and molecular weight of 354.25 g/mol. 1,2,3,4,5,6,7 -Tris (1 methylethylidene) -D glycero D gulo heptitol is a complex carbohydrate that is used in the synthesis of oligosaccharides and monosaccharides.</p>

<p>(1S) -1- [(2S, 3R) - 3- Hydroxy- 1- (2-hydroxyethyl) - 2- azetidinyl] -1, 2- ethanediol is a carbohydrate that is modified by fluorination and methylation. This product is custom synthesized to your specifications. It has been shown to be effective in glycosylation reactions and click chemistry.</p>

<p>Hybrid Glycan, 2-AB labelled is a custom synthesis of a high purity glycosylation product. This synthetic oligosaccharide includes saccharides that are labelled with 2-AB. The modification is Click chemistry and provides a method for attaching the label to the sugar molecule. This product is not found in nature or existing in cells or organisms. It is used as a research tool in immunology, cell biology, and structural biology applications.</p>

<p>GDP-L-fucose is a natural fucosyl donor and substrate for fucosyltransferases (FUT) that catalyses the fucosylation of, for example, human milk oligosaccharides or glycoproteins. GDP-L-fucose is widely used in (chemo)enzymatic synthesis of glycans. Cymit Quimicaesis of GDP-L-fucose, a nucleotide sugar consisting of an L-fucose that is β-glycosidically linked to the nucleotide guanosine diphosphate (GDP), is achieved either through de novo synthesis via GDP-mannose or through a salvage pathway from free fucose. Fucosylation is catalysed by fucosyltransferases (~ 13 FUT genes have been identified in the human genome to date) to generate α-1,2, α-1,3, α-1-4 and α-1-6 linkages of fucose to other sugars, as well as direct linkages to peptides, with release of GDP (Lairson, 2008).</p>

<p>(3R, 5R) -1-Benzyl-3, 4, 5- piperidinetriol hydrochloride is a synthetic compound that is used for the production of oligosaccharides and saccharides. This molecule is a part of the glycosylation reaction and has been modified to produce a variety of carbohydrate products. The CAS number for this compound is 6078-73-5 and it can be synthesized in various lengths. The chemical name for this compound is (3R, 5R)-1-(benzyloxycarbonyl)-3,4,5-piperidinetriol hydrochloride.</p>

<p>Anthrose is a high purity, custom synthesis, and oligosaccharide. It can be modified with fluorination, glycosylation, and methylation. Anthrose is used for the synthesis of complex carbohydrate.</p>

<p>Sodium carboxymethyl dextran (CM-dextran) is a white, odourless and tasteless powder, which is freely soluble in water or electrolyte solutions. The product has a pronounced polyanionic character, due to the high degree of carboxyl substitution.  Applications that have been described for CM-dextran include carriers of paramagnetic contrast agents, preparation of conjugates of pharmacologically active compounds and CM-dextrans in biosensors.  A number of other uses in cosmetics, agriculture, foods, paints and textiles have been the subject of patent applications.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose is a small molecule that binds to the D1 protein of the glycolytic enzyme phosphofructokinase and inhibits enzymatic activity. This inhibitor is used in diagnostic procedures to identify mutations in the gene encoding for this protein, which is associated with familial and sporadic aneurysms. The inhibitor is also used to study the pathogenic mechanism of aneurysms. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy--D--glucopyranose has been shown to inhibit cell nuclei polymerase in vitro and prevents cell division in vivo.</p>

<p>N,O-Didesmethyl venlafaxine D-glucuronide is a custom synthesis, complex carbohydrate. It is an Oligosaccharide with CAS No. that is Polysaccharide and Modification. It has Methylation and Glycosylation. The saccharide in the molecule is a sugar or Carbohydrate and sugar. The high purity of the product makes it Fluorination and Synthetic.</p>

<p>Methyl 2-deoxy-D-ribofuranoside is a methylglucoside that is synthesized by the reaction of thiourea with chloroacetic acid. The anomers of this compound are atypical and the product can be obtained in high yield (70%) by the use of chromatographic purification. This chemical has been used to produce a variety of compounds including carbamates, chloroacetamides, sulfonamides and others. Methyl 2-deoxy-D-ribofuranoside is also an intermediate for asymmetric synthesis. It can act as a catalyst for reactions involving alkali metals and nucleophiles such as chloride, hydantoin and dimethylformamide. The structure of this molecule has been determined by nmr spectroscopy and its 1H NMR spectrum is consistent with that predicted from its molecular formula.</p>

<p>3-O-benzyl-D-xylose is a sugar that belongs to the group of dimethyl, diisobutylaluminium, dicarboxylate, malonate, oxygenated, acetylation, cyclopentane. It has been shown to be effective in cleavage and condensation reactions. 3-O-benzyl-D-xylose can be used in the synthesis of pyridinium chlorochromate and chlorochromate. This compound also reacts with pyridinium via hydride reduction and hydroxide cleavage.</p>

<p>Key synthetic precursor for the synthesis of lacto-oligosaccharides</p>

<p>N- [(3R, 4R, 5R) - 4- (Acetyloxy) - 5- [(acetyloxy) methyl] -1- benzyl- 3- pyrrolidinyl] -acetamide is a custom synthesis of our company. It can be used to synthesize oligosaccharides and polysaccharides by click modification. It is also used for fluorination of complex carbohydrates, saccharide and sugar.</p>

<p>1,2,3,4-Tetra-O-acetyl-6-O-trityl-b-D-galactopyranose is a high purity glycosylation product. It has been custom synthesized and modified with Methylation, Click modification, Polysaccharide and Fluorination. The CAS number of this compound is 124648-92-6.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarodecaose is reported to have potential for novel cosmeceuticals.</p>

<p>Globoside is the most abundant neutral glycolipid in the erythrocyte membrane.</p>

<p>1,2,3,4,6-Penta-O-acetyl-5-thio-D-galactopyranose is an oligosaccharide that is synthesized by the fluorination of a 5-thiogalactopyranosyl fluoride and subsequent glycosylation. It can also be made by methylation of a 3,4,6 pentaacetylgalactosamine with formaldehyde and sodium cyanoborohydride. It is a complex carbohydrate that has been shown to have antiviral activity against HIV.</p>

<p>Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide, CAS No., Polysaccharide. Glycosylation. Sugar. Carbohydrate. Complex carbohydrate.</p>

<p>D-Glucosamine-6-O-sulphate is a disaccharide that is a component of heparin. The molecular docking analysis of this drug with the target proteins, d-glucosamine 6-O-sulphate and l-iduronic acid, has been performed using the protein data sets from proteomics. D-Glucosamine-6-O-sulphate has been found to be related to psoriasis patients in urine samples. The macroscopic and microscopic structure of this drug was also studied and characterized by liquid chromatography.</p>

<p>Arabinose is a pentose sugar that has been shown to have antimicrobial properties. It inhibits the growth of bacteria by binding to their ribosomes and interfering with protein synthesis. Arabinose has also been shown to inhibit the growth of bone cancer cells in mice, which may be due to its ability to stimulate the production of growth factor-β1. The biochemical properties of arabinose are similar to those of d-arabinose, an active analogue that is used as a water vapor pump inhibitor. X-ray crystal structures have been obtained for both compounds, and they show that they differ in the position of one hydrogen atom on the sugar ring.</p>

<p>Glycyl-Oligosaccharidesmannose 6 are custom synthesized and modified to contain fluorine atoms. These compounds are used as a reagent in organic synthesis, chemical modification, and biochemistry. They have been used for the methylation of saccharide and carbohydrate molecules, including glycosylation reactions. Glycyl-Oligosaccharidesmannose 6 can be used for the preparation of polysaccharides, which are complex carbohydrates.</p>

<p>2,4-Dideoxy-2,4-difluoro-D-glucose is a fluorinated glucose analog that has been synthesized to be used as an imaging agent for positron emission tomography (PET) and single photon emission computed tomography (SPECT). It is labeled with fluorine-18 and can be metabolically incorporated into the cellular glycolytic pathway. 2,4-Dideoxy-2,4-difluoro-D-glucose emits positrons that are detected by PET or SPECT cameras. The incorporation of 2,4-dideoxy-2,4-difluoro--D--glucose into the glycolytic pathway allows it to be used as a marker for positron emission tomography.</p>

<p>Methyl b-D-arabinopyranoside is a fluorine containing molecule that has been shown to be an excellent marker for suberin. It is insoluble in water, and can be detected by resonator diffraction. The chemical composition of methyl b-D-arabinopyranoside was determined using liquid crystal composition and plates. A polymer particle with a macroscopic size was used to determine the fluorescence of methyl b-D-arabinopyranoside. Fluorescence analysis showed that methyl b-D-arabinopyranoside is a green fluorescent material with a maximum emission wavelength of 514 nm. Hydroalcoholic extraction was used to isolate this compound from the plant Ricinus communis L., where it was found in constant proportions.</p>

<p>Hyaluronic acid is a polysaccharide containing repeating disaccharide units of β-1,3-N-acetyl glucosamine and β-1, 4-glucuronic acid. A series of unsaturated oligosaccharides (oligouronic acids) are released from hyaluronic acid by the action of hyaluronidase on the umbilical cord (Weissman, 1954). This tetrasaccharide ammonium salt and other enzymatically produced polymer homologs have been of value in the study of hyaluronic acid metabolism in both healthy and diseased tissues (Hascall, 2019).</p>

<p>Xylan is the most abundant noncellulosic polysaccharide present in both hardwoods and annual plants. Xylan is found mainly in the secondary cell wall as part of the hemicellulose fraction and is considered to form an interface between lignin and other polysaccharides. In their simplest forms, xylans are linear homopolymers of β-1,4-xylose residues but can also form complex heterogenous and polydispersed glycans.</p>

<p>3,5-o-Benzylidene-d-lyxuronic acid is a carbohydrate derivate that is used in the modification of oligosaccharides and polysaccharides. 3,5-o-Benzylidene-d-lyxuronic acid can be synthesized by reacting 3,5-dibenzyloxybenzoic acid with an alcohol or amine. This compound has a CAS number of 4891-57-3. It is a white to off white powder that has a molecular weight of 264.24 g/mol and chemical formula C21H28O4. The sugar chain contains an acetal group at the C2 position of the sugar ring and two benzyl groups at the C6 position of the sugar ring. 3,5-o-Benzylidene-d-lyxuronic acid is soluble in water and acetone but insoluble in ether or chloroform.</p>

<p>Sodium carboxymethyl dextran is a white, odourless and tasteless powder, which is freely soluble in water or electrolyte solutions. Applications that have been described for carboxymethyl dextran include carriers of paramagnetic contrast agents, preparation of conjugates of pharmacologically active compounds and carboxymethyl dextrans in biosensors.  A number of other uses in cosmetics, agriculture, foods, paints and textiles have been the subject of patent applications.</p>

<p>5,6-Dichloro-5,6-dideoxy-b-L-talofuranose is a carbohydrate. It is a saccharide with a molecular formula of C7H8Cl2O4 and a molecular weight of 245.1. This compound has been modified by fluorination and methylation. 5,6-Dichloro-5,6-dideoxy-b-L-talofuranose is stable in the presence of acid or base at room temperature and has a melting point of &gt;200°C. The CAS number for this compound is 677638-78-0. 5,6-Dichloro-5,6-dideoxy-b -L -talofuranose is available for custom synthesis to order with high purity and can be glycosylated or click modified to order.</p>

<p>Ezetimibe-D-glucuronide D4 is a deuterated version of the active molecule, ezetimibe. It is a white to off-white crystalline powder with a molecular weight of 592.1 Da and an empirical formula of C31H41NO7F2·C6H8O7. It is soluble in ethanol and water, and insoluble in ether or chloroform.</p>

<p>4-Methoxyphenyl 4-O-(4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-O-levulinoyl-b-D-glucopyranosyl)-3,6-di-O-benzyl -2,6'-dideoxygalactopyranoside is a modification of the natural carbohydrate galactose. The sugar moiety has been methylated and glycosylated with a levulinate ester and then fluorinated. This compound is highly pure and can be synthesized on custom order.</p>

<p>To assess substrate specificity of galactokinase from S. pneumoniae</p>

<p>GT1b (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b is one of the major gangliosides in neuronal and glial membranes, it interacts with the myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishik,i 1996), as well as for viruses, a few examples include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).</p>

<p>Benzyl 3-amino-3-deoxy-a-D-mannopyranoside HCl is a high purity, custom synthesized, synthetic carbohydrate. It has been modified with fluorination and glycosylation. Modification of the carbohydrate is done by methylation or oligosaccharide addition. This product is a complex carbohydrate that has been synthesized from monosaccharides and saccharides. The carbohydrates are saccharide chains composed of carbon, hydrogen, and oxygen atoms in a straight or branched chain. Carbohydrates can be classified according to their number of sugar units: mono-, di-, tri-, tetra-, penta-, hexa-, hepta-, octa-, nona-.</p>

<p>Methyl 5-Azido-3-O-benzyl-5-deoxy-1,2-O-isopropylidene-D-galactofuranoside is a custom synthesis of a monosaccharide that can be fluorinated, methylated and modified with the click reaction. It is an oligosaccharide that can be saccharified by glycosylation or polysaccharided by glycosylation. It is a carbohydrate that contains a complex carbohydrate.<br>Methyl 5-Azido-3-O-benzyl-5-deoxy-1,2--O--isopropylidene--D--galactofuranoside has CAS No.</p>

<p>The family of sporadically occurring benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside is characterized by chromosome terminal deletions, cytogenetic abnormalities, and phenotypes. The sporadically occurring benzyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a member of the glucosamine family. It is characterized by chromosome terminal deletions, cytogenetic abnormalities, and phenotypes.</p>

<p>1,2,3-Tri-O-benzoyl-4,6-O-(4-methoxybenzylidene)-b-D-galactopyranose is a synthetic glycosylation product of 3,6-dideoxygalactose and 1,2,3,4,6-pentaacetyl bromide. It has been subjected to fluorination and methylation reactions. The compound has been found to be effective in the treatment of tuberculosis.</p>

<p>Tetra-mannuronic acid sodium salt (β-1,4-linked sodium mannuronotetraose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.  Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>Hydroxyethyl cellulose (EHEC) is a non-ionic, water-soluble cellulose derivative produced by introduction of ethylene oxide groups to the hydroxyl groups of the cellulose backbone. Hydroxyethyl cellulose is useful as a water thickener, rheological control additive, protective colloid, binder, stabilizer, suspending agent and film former.  It is used in many industrial applications including latex paints, emulsion polymerization, petroleum, paper, pharmaceuticals, cosmetics and many other applications.</p>

<p>2,3-O-Isopropylidene-L-lyxonic acid-1,4-lactone is an enantiopure compound that is a member of the glycoside family. It has been shown to inhibit the activity of glycosidases, which are enzymes that hydrolyze glycosides. 2,3-O-Isopropylidene-L-lyxonic acid-1,4-lactone has an ambiguous stereochemistry due to its carbon chains and catalytic groups. The conformational analysis of this compound reveals that it can be classified as a chiral molecule because it lacks a plane of symmetry. Crystallographic analysis has shown that 2,3-O-Isopropylidene-L-lyxonic acid-1,4-lactone adopts a dimeric form and crystallizes in an asymmetric unit cell with space group P2(1)22(1).</p>

<p>Substrate for xylosyltransferases</p>

<p>6'-Fucosyllactose is a fucosylated form of lactose, which is a complex carbohydrate. It is a custom synthesis and has been synthesized in high purity. 6'-Fucosyllactose has CAS No. 80756-86-1 and can be found as an oligosaccharide or polysaccharide. 6'-Fucosyllactose is a monosaccharide that has been methylated and glycosylated to increase its stability. The saccharides are modified with fluorination to make it more soluble in water and to improve its solubility in organic solvents.</p>

<p>3-O-(a-L-fucopyranosyl)-D-galactopyranose is a glycosidic residue that is part of the β-D-Galactoside. It is an amino acid that is used to form carbohydrates. The chemical formula for 3-O-(a-L-fucopyranosyl)-D-galactopyranose is C 12 H 18 O 11 . The molecular weight of 3-O-(a-L-fucopyranosyl)-D-galactopyranose is 308.</p>

<p>L-Menthylglucoside is a custom synthesis, complex carbohydrate. It has CAS number 16203-27-3 and is an Oligosaccharide and Polysaccharide. L-Menthylglucoside has been modified with methylation and glycosylation, which may be due to its Click modification. L-Menthylglucoside is a sugar that is high purity, fluorinated, and synthetic.</p>

<p>Monosialyllacto-N-hexaose II is a synthetic, fluorinated oligosaccharide that is synthesized by glycosylation of the sugar monosialyllactose. Monosialyllacto-N-hexaose II has a molecular weight of 514.5 Da and is soluble in water. It can be used for applications such as custom synthesis, modification of complex carbohydrates, or click chemistry.</p>

<p>Methyl-2,3,4,6-tetra-O-acetyl-alpha-D-mannopyranoside is a sugar that is synthesized by the methylation of an alpha-D-mannopyranoside. This compound can be customized for any application and is available in high purity. It is used as a building block for polysaccharides and oligosaccharides. Methyl-2,3,4,6-tetra-O-acetyl-alpha-D-mannopyranoside has been shown to have many applications including being used as a click modification substrate. The synthesis of this compound can be done by fluorination or glycosylation.</p>

<p>Monosialyl, monofucosyllacto-N-neohexaose is a synthetic oligosaccharide. It has a molecular weight of 1205. The compound has been modified with a click modification and fluorination, and has been shown to be stable in the presence of acid, base, and heat. The compound is also high purity and can be synthesized on request. Monosialyl, monofucosyllacto-N-neohexaose is an example of a complex carbohydrate that contains both a sugar and polysaccharide component. The sugar component is composed of one monosaccharide: sialic acid. The polysaccharide component consists of six disaccharides: two lactose molecules linked with one glucose molecule each. Monosialyl, monofucosyllacto-N-neohexaose is used as an artificial sweetener in food products such as cookies or cakes</p>

<p>1,2,3,4,6-Penta-O-acetyl-a-D-glucopyranose is a chemical compound that is an ester of the sugar penta-O-acetyl-a-D-glucopyranose and acetic acid. It has been shown to inhibit the activity of a number of enzymes, including proteins such as phospholipases C and D and fatty acid synthetases. The 1,2,3,4,6-penta-O-acetyl analogues have been shown to be effective in inhibiting model systems for the pathogenesis of inflammatory bowel disease and cancer. The hydroxyl group on the sugar ring may be important for binding to these enzymes.</p>

<p>The modification of this product has been completed with a high level of purity and the CAS number is 57-49-6. It is an oligosaccharide that is a complex carbohydrate. This product can be synthesized through custom synthesis and it is a synthetic product. It is classified as a monosaccharide, methylation, glycosylation, and polysaccharide. The chemical formula for this compound is C12H14O11. This compound has been fluorinated to increase its solubility in water.</p>

<p>A rare sugar, prebiotic fibre and inhibitor of α-glucosidases. It inhibits animal-, plant- and microorganism-derived α-glucosidases I. In rodent models for diabetes, it ameliorates arachidic acid-induced liver injury and reduces hepatic inflammatory markers.</p>

<p>1-6-Bis-O-tert.butyldimethylsilyl-3,4-O-isopropylidene)-D-mannitol is a glycosylation agent that has been used in the synthesis of complex carbohydrates. This compound is synthesized by the click reaction between 1,6-bis(tert.butyldimethylsilyl)glycerol and aldehyde 3,4-(O)-isopropylidene)-D-mannitol. It is a high purity product with CAS No. 65425-06-7 and can be customized for your needs.</p>

<p>D-Glucuronic acid (GlcA) is D-glucose with position six oxidised to a carboxyl group (Collins, 2006). It is a common component of a number of gums and mucilages structurally related to pectins, where it is can be present as a terminal non reducing end residue (Renard, 1999). Glucuronic acid is also found in bacterial polysaccharides, such as, xanthan gum produced by Xanthomonas campestris (Faria, 2011), and in glycosaminoglycans, such as, heparan sulfate (Casale, 2020).</p>

<p>L-Erythrono-1,4-lactone is a dicarboxylic acid that is synthesized from l-threonic acid and d-arabinose. L-Erythrono-1,4-lactone is biosynthesized by the conversion of l-serine to pyruvate and then to erythrose 4-phosphate. This compound is also produced by the oxidation of ascorbic acid and can be used for the synthesis of dermatan sulfates. The accumulation of L-Erythrono-1,4-lactone in high concentrations has been found in patients with dermatan sulfate deficiency.</p>

<p>Benzyl 4,6-O-benzylidine-b-D-galactopyranoside is a benzoylated sugar. It is prepared by reacting benzoyl chloride with benzene and then with the sugar in an equimolar ratio. The reaction proceeds via a nucleophilic substitution at the 2' position of the sugar followed by an elimination of water. Benzyl 4,6-O-benzylidine-b-D-galactopyranoside reacts with dibutyltin to form a benzoylated tin compound that can be used as a catalyst for organic synthesis.</p>

<p>Sorbitol, also known as glucitol, occurs widely in plants, such as, the fruits of the Sorbus and Crataegus spp.  Commercially it is produced by the catalytic hydrogenation of glucose (Collins, 2006).  Sorbitol is approved as a sugar substitute with the E number 420 and has ‘generally recognized as safe’ status (GRAS) from the US Food and Drug Administration. It is about 60% as sweet as sucrose and is a mild laxative.  Sorbitol has a wide range of other functional properties, including: humectancy, plasticizing ability, non-cariogenicity, and good chemical stability in harsh conditions, such as, alkaline pH and heat. Toothpaste production is the second largest application of sorbitol, accounting for 50,000 tons a year in Western Europe alone.  Other important uses of sorbitol as a humectant, include: formulation of cough syrups, multivitamin preparations, emulsions, and suspensions (O’Neil, 2013).</p>

<p>Sodium Tetragalacturonate (α-1,4 sodium tetrgalacturonate) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restore development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>(5R, 8S, 9S) -8- [(4S) - 2, 2- Dimethyl- 1, 3- dioxolan- 4- yl] - 9- hydroxy- 2, 2- dimethyl- 1, 3, 7- trioxaspiro[4.4] nonan- 6- on e is an Oligosaccharide that is synthesized by click chemistry. The product is a synthetic glycosylation that contains fluorine atoms and methyl groups. It has a purity of 99% and a CAS number of 5963872.</p>

<p>Component of peptidoglycan in bacterial cell walls. Peptidoglycan is a mesh-like polymer, made of a glycan backbone containing alternating subunits of N‐acetylglucosamine (GlcNAc) and N‐acetylmuramic acid (MurNAc). An enzyme substrate that is used to characterize and differentiate MurNAc and GlcNAc kinases.</p>

<p>Ethyl 2,3-di-O-benzoyl-4,6-O-benzylidene-b-D-thiogalactopyranoside is a high purity custom synthesis sugar. This product contains the Click modification, fluorination and glycosylation modifications. It can be used in the synthesis of oligosaccharides, monosaccharides and saccharides. Ethyl 2,3-di-O-benzoyl-4,6-O-benzylidenebDthiogalactopyranoside is used to synthesize complex carbohydrates.</p>

<p>6-Amino-6-deoxy-D-lactosylamine is a modified sugar that is used to synthesize glycosides. It is also used as a reagent for the methylation of saccharides and polysaccharides. This product can be custom synthesized or ordered from our catalog. We offer high purity 6-amino-6-deoxy-D-lactosylamine, which has been chemically modified with fluorine and has a CAS number of 7092-12-3. It is available in different quantities and can be ordered with other custom modifications, such as Click chemistry.</p>

<p>L-Arabinopyranosyl thiosemicarbazide is a carbohydrate that belongs to the group of saccharides. It is a synthetic, fluorinated monosaccharide that has been modified with methyl groups and glycosylation. L-Arabinopyranosyl thiosemicarbazide is used in the synthesis of complex carbohydrates and oligosaccharides. This compound can be custom synthesized according to your specifications. L-Arabinopyranosyl thiosemicarbazide is available at high purity and low price.</p>

<p>Ziyuglycoside II is a steroidal alkaloid that has been shown to have anti-angiogenic properties. It is a natural compound extracted from the Chinese herb ziyuglycoside. This compound has been shown to inhibit the activation of toll-like receptor 4, which plays an important role in inflammation and immunity. Ziyuglycoside II also inhibits the production of reactive oxygen species and autophagy, leading to cell death by apoptosis. This compound has been shown to be effective against bowel disease and epithelial mesenchymal transition (EMT). Ziyuglycoside II has also been shown to have matrix effects on the cells Hl-60, which are related to tumor metastasis.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>The 1-O-acetyl-2,3:5,6-di-O-isopropylidene-D-mannofuranose is a custom synthesis. It is fluorinated at the 6 position and methylated at the 3 position. This modification is done to give it an acetyl group on the 1 carbon and a hydroxyl group on the 2 carbon. The compound has been synthesized by modifying the natural sugar mannose with an acetyl group and a hydroxyl group. The compound has not been modified in any other way as of yet, but it would be possible to add more modifications such as glycosylation or polysaccharide formation.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>4-O-Benzyl-D-mannose is a high purity, custom synthesis sugar with Click modification, fluorination and glycosylation. The CAS No. for this compound is 108611-67-0. 4-O-Benzyl-D-mannose is an oligosaccharide monosaccharide saccharide carbohydrate complex carbohydrate with the chemical formula C5H6O5 that has a molecular weight of 174.11 g/mol. This compound can be used to synthesize polysaccharides, which are carbohydrates that contain more than ten monosaccharides and are found in plant cell walls and other biological polymers such as chitin, cellulose, and glycogen. 4-O-Benzyl-D-mannose is also used in the synthesis of saccharides that are found in glycoproteins or proteoglycans.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Fluorination is a process that has been used to synthesize various types of chemical compounds. Fluorination is usually achieved by reacting an organic compound with elemental fluorine gas, or dissolved fluoric acid. Fluorination may also be carried out with silicon tetrachloride, sulfur tetrafluoride, or other fluorinating agents. The term fluorination refers to the substitution of hydrogen atoms in an organic molecule with fluorine atoms. This reaction is most often done on unsaturated carbon-carbon bonds, because these are more reactive than others. Monosaccharides are sugar molecules that consist of one sugar unit and two hydroxyl groups (CAS No. 54497-89-1). They are classified as simple sugars because they can be hydrolyzed into their component parts by hydrolysis or oxidation. Polysaccharides are carbohydrates consisting of long chains of monosaccharides (sugar molecules) bonded together by glycosidic linkages</p>

<p>The polysaccharide, known as glucuronoxylomannan - produced by fruit bodies and in pure culture conditions - has been shown to consist of a mannan backbone that is glycosylated with xylan and glucuronic acid chains in a regular repeating structure. Laboratory tests have associated a number of biological activities with Cryptococcus neoformans glucuronoxylomannan, including immunostimulatory, antidiabetic, anti-inflammatory, hypocholesterolemic, hepatoprotective, and antiallergic effects.<br>The image was kindly provided by Dr. Chris Lawson.</p>

<p>(+)-Lyoniresinol-3a-O-(6''-3,5-dimethoxy-4-hydroxybenzoyl)-b-D-glucopyranoside is a custom synthesis that is a methylated oligosaccharide with a 3,5-dimethoxy 4'-hydroxybenzoyl group. This compound has CAS number and is a complex carbohydrate that has been modified with fluorination. It is highly pure and can be used in the modification of monosaccharides or sugars.</p>

<p>Lewis Y-O-(CH2)8-biotin is a carbohydrate with the chemical formula (CHO)(CO)3OH. It is a methylated and glycosylated oligosaccharide that has been custom synthesized for use in biotechnology applications. Lewis Y-O-(CH2)8-biotin has been fluorinated at the C5 position to improve its stability and prevent hydrolysis, which may be due to its high purity. This carbohydrate is not commercially available and must be custom synthesized.</p>