Glicoscienza

<p>N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is a modification of the natural sugar N-acetylneuraminic acid. It can be synthesized by reacting 1,2,3-¹³C3]cytidine with sodium hydroxide and acetic anhydride in methanol. It is a carbohydrate that can be found in many plants and animals. This compound has been shown to inhibit glycosylation and methylation reactions. N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is also a monosaccharide that belongs to the group of sugars. Due to its high purity and availability, this substance can be used as a substitute for sialic acid in research experiments.</p>

<p>This compound has been used in the study of cellulase kinetics</p>

<p>L-Threose is a sugar molecule that is used as a structural component of DNA and RNA. It is also an important part of the energy metabolism in cells. L-Threose can be enzymatically inactivated by glycosidases, which are enzymes that hydrolyze glycosidic bonds. The inhibition of glycosidases by L-threose may be useful for the prevention or treatment of diseases associated with enzyme activity, such as diabetes mellitus type II. L-Threose has been shown to have inhibitory properties against sephadex G-100, a membrane protein found in bacteria. L-Threose may be useful as a control agent for research into the response element of polymerase chain reaction (PCR).</p>

<p>Ethyl 2-O-benzyl-b-D-thioglucopyranoside is a custom synthesis product. It is an oligosaccharide that contains a saccharide monomer unit with a carbohydrate chain containing between 3 and 10 monomer units. This product has been modified to include fluorine atoms, which confers resistance to degradation by enzymes. The product has been synthesized from ethyl 2-O-benzyl-b-D-thioglucopyranoside and 2,4,5,6-tetrafluoroethanol in the presence of sodium methoxide in methanol at 120 °C for 24 hours.</p>

<p>4-Aminophenyl-alpha-D-glucopyranoside is a natural product that has been found to be an antigen. The compound has been shown to have anticancer activity, which may be due to its ability to inhibit the growth of cells and induce apoptosis. 4-Aminophenyl-alpha-D-glucopyranoside also possesses magnetic properties. The chemical structure of this compound is characterized by an acrylate group, which is a small organic molecule with two carbon atoms and one oxygen atom. This compound is synthesized in a preparative manner using methoxy, ethyl bromoacetate, and mesitylene in the presence of irradiation. NMR spectroscopy can be used for the characterization of this compound as well as other compounds with similar structures that are catalytic in nature.</p>

<p>4-O-Acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl trichloroacetimidate is a methylated saccharide that can be obtained through the Click modification of an oligosaccharide. It is a custom synthesis that has been modified with fluorination. This product is available in high purity and has been glycosylated. It is also a synthetic carbohydrate with a complex structure.</p>

<p>1-O-Methyl-α-D-galactopyranoside is a gratuitous α-galactosidase inducer.</p>

<p>4-Azido-4,6-dideoxy-2,3-O-isopropylidene-D-talono-1,5-lactone is an oligosaccharide that is synthesized using the Click chemistry. It is a modification of the natural product methylated L -rhamnosyl-(1→2)-D -talonolactone. 4-Azido-4,6-dideoxy-2,3-O-isopropylidene D -talono 1,5 lactone has been shown to inhibit the growth of Mycobacterium tuberculosis and Mycobacterium avium complex bacteria.</p>

<p>9-O-Acetyl-N-acetyl-neuraminic acid is a sialic acid produced by the human body. It can be found in human serum and has been shown to have inhibitory properties against viruses, such as hepatitis B and C viruses. 9-O-Acetyl-N-acetylneuraminic acid binds to the α1-acid glycoprotein in the blood, which can reduce its ability to bind to other molecules. This leads to a lower concentration of 9-O-acetylneuraminic acid in the blood. This molecule also has chemical biology properties that are being studied for their effects on biological processes such as histological analysis, receptor molecule binding, polymerase chain reaction (PCR), and mucin gene transcription. 9-O-Acetylneuraminic acid also has antihistamine activities that may be due to its ability to block histamine receptors or inhibit histamine release.</p>

<p>2-Acetamido-2-deoxy-D-lyxojirimycin is a carbohydrate that is modified by fluorination, methylation, glycosylation, and click modification. The compound is a synthetic monosaccharide that is used in the synthesis of complex carbohydrates. 2-Acetamido-2-deoxy-D-lyxojirimycin has CAS number 1207673-74-2 and can be custom synthesized to meet your requirements for purity and quality.</p>

<p>Building block for synthesis of oligosaccharides</p>

<p>Hydroxypropyl methylcellulose (HPMC or hypromellose) is a semisynthetic, inert and viscoelastic polymer that is used as eye drops and as semi-synthetic substitute for tear-films. When applied, a hypromellose solution acts to swell and absorb water, by increasing the thickness of the tear-film, resulting in decreased eye irritation.  In addition to its use in ophthalmic liquids, hypromellose has been used as an excipient in oral tablet and capsule formulations, where, depending on the grade, it functions as controlled-release agent. It is also used as a binder and as a component of tablet coatings.  Hypromellose in aqueous solution, unlike methylcellulose, exhibits thermal gelation properties. HPMC is approved as a food additive, emulsifier, thickening and suspending agent, and as an alternative to animal gelatin (Codex Alimentarius code (E number) is E464).</p>

<p>Neocarradecaose-41,3,5,7,9-penta-O-sulfate sodium salt is a synthetic oligosaccharide that is used as an active ingredient in anti-tuberculosis drugs. It has been shown to have strong inhibitory activity against Mycobacterium tuberculosis. Neocarradecaose-41,3,5,7,9-penta-O-sulfate sodium salt is also a good substrate for glycosylation reactions and can be modified by methylation or click chemistry. This compound is water soluble and suitable for dissolving in organic solvents. The purity of the compound is over 98%.</p>

<p>Hexa-mannuronic acid sodium salt (β-1,4-linked sodium mannuronohexaose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>Immobilised on Fractogel with glycosylamine formation of the monosaccharide</p>

<p>2, 4-Anhydro-N-benzyl-3,5-O-[(R)-benzylidene]-6-deoxy-D-mannonamide is a sugar. It has high purity and can be custom synthesized to suit your needs. This sugar can be modified with a click modification or fluorination. It can also be glycosylated or methylated for your desired outcome. The CAS number for this sugar is 29098-86-2. The molecular weight of this sugar is 359.8 g/mol and the chemical formula is C14H27NO4. The Oligosaccharide content for this sugar is between 1% and 10%. The Monosaccharide content for this sugar is between 100% and 90%. This product has been classified as complex carbohydrate by the IUPAC nomenclature system.</p>

<p>Glupentaacetate is a synthetic, fluorinated sugar that is used in the synthesis of complex carbohydrates. It has been shown to be a useful tool for the modification of glycosylations, polysaccharides and saccharides. Glupentaacetate has been modified with a methyl group at the C-2 position. This modification leads to increased reactivity and stability, in addition to being useful for click chemistry. Glupentaacetate is also stable under acidic conditions, making it an excellent choice for use in organic synthesis.</p>

<p>Alpha-Chloralose (max. 20% beta-anomer) is a chemical compound primarily used as a sedative and for rodent control. It is synthesized through a chemical reaction involving glucose and chloral, creating a substance with unique physiological properties. Its mode of action primarily involves depressing the central nervous system, leading to reduced responsiveness and hypothermia in targeted organisms. Alpha-Chloralose induces symptoms that facilitate its application as a tranquilizer, particularly in small mammals and birds during scientific research. Additionally, due to its efficacy in lowering metabolic rates, it is utilized as a rodenticide. Within this context, it serves to humanely control rodent populations by inducing hypothermic conditions, leading to a humane death. Its dual functionality—both as a sedative and a rodenticide—makes it a versatile tool in scientific research and pest management. The specification of a maximum 20% beta-anomer content ensures a standardized formulation, enhancing its reliability and consistency for experimental and practical applications.</p>

<p>L-Allose is a monosaccharide that has the chemical formula HOCH(OH)CH(OH)CHO. L-Allose is a stereoisomer of D-allose, which differs in the orientation of the hydroxyl group on its asymmetric carbon atom. L-Allose can be produced by condensation of glucose and galactose, or by hydrogenation of allulose. The enzyme immobilized on alumina catalyzes the synthesis in high yield. L-Allose has been used as a carbon source for molecular modeling studies and as an enzymatic reaction substrate in sugar alcohols production.</p>

<p>A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus vesiculotus, Ascophyllum nodosum, Alaria and Macrocystis pyrifyra (illustrated) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates, although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta.<br>The fucose content of this fucan is approx. 31% and it also contains galactose (approx. 2.2%), uronic acid (approx. 12.4%) and sulfate (approx. 32.5%).<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Dabigatran 3-acyl glucuronide is a glycosylation product of the anti-coagulant drug dabigatran. It is synthesized by the reaction of an ester, such as acetyl chloride, with a sugar, typically glucose. Dabigatran 3-acyl glucuronide has been shown to have a high purity and no detectable impurities. The CAS number for this compound is 1073498-74-4.</p>

<p>Ethyl 2-O-benzoyl-3-O-benzyl-4-O-levulinoyl-b-D-thioglucopyranoside is a glycosylation product of ethyl levulinate and 3,4,6,7,8,9,10,11,12-hexahydroxybenzoate. This compound has undergone methylation at the C2 position of the benzoic acid moiety and click modification at the C1 position of the benzoyl group. It is a polysaccharide that is used as a fluorinating agent in organic synthesis. Ethyl 2-O-benzoyl-3-O-benzyl-4-O-levulinoyl b -D--thioglucopyranoside is an oligosaccharide with six monosaccharides attached to each other by glycosidic bonds. The CAS No</p>

<p>Phosphatidyl inositol-10mg/ml solution in chloroform:methanol(4:1) is a carbohydrate that is a complex carbohydrate. It is synthesized by the modification of the phosphatidyl inositol molecule with fluorination and methylation. The CAS number for this compound is 91228-52-5. This product can be custom synthesized as per customer's requirements. It has a high purity and excellent quality, and is available at competitive prices.</p>

<p>This is a custom synthesis. It can be used as a sugar, click modification, fluorination, glycosylation, and synthetic. This product is CAS No. 634-74-8 with many modifications to make it work for your needs. We have oligosaccharides and monosaccharides that can be modified to create complex carbohydrates.</p>

<p>3, 4:5, 6- Di- O-isopropylidene -D- gluconic acid methyl ester is a modification of the natural product D-glucose. It is an oligosaccharide with a complex carbohydrate structure. This product can be custom synthesized to meet your requirements and specifications. In addition, it has high purity and CAS No.</p>

<p>Methyl 3,5-di-O-(p-chlorobenzoyl)-a-D-ribofuranoside is an organic compound. It is a synthetic product that is used in the synthesis of saccharides and polysaccharides. This chemical can be modified with Click chemistry to create a glycosylate or fluorinated complex carbohydrate. The compound has CAS number 62700-92-3 and can be custom synthesized to meet customer specifications.</p>

<p>6-O-Trityl-D-mannopyranose is a modified sugar that has been synthesized for use as a glycosylation agent. It is an O-glycoside of mannose and is usually used in the synthesis of complex carbohydrates. 6-O-Trityl-D-mannopyranose can be fluorinated, methylated, or click modified to produce desired derivatives. This product can also be used to modify saccharides or oligosaccharides.</p>

<p>Specific, potent and competitive inhibitor of α-L-fucosidase with Ki of 10 nM. In human breast cancer cells, it causes increase of fucosylation on cell surface molecules such as Lewis X antigen (CD15) and CD44 glycoprotein. The 1-deoxyfuconojirimycin treatment increases invasiveness of cancer cells.</p>

<p>Please enquire for more information about Glycogen, ex oyster including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Hyaluronic acid potassium, from bacteria including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Neu5GcAc[1Me,4789Ac]a(2-6)Gal[24Bz,3Bn]-b-MP is a custom synthesis of an oligosaccharide. This complex carbohydrate has a CAS No. and has been modified to include methylation, glycosylation, and click modification. The sugar is a high purity fluorinated synthetic saccharide with a glycosylation site at the reducing end of the chain.</p>

<p>N-Acetyl-L-neuraminic acid is a glycosylation compound that is an important component of the cell wall of Gram negative bacteria. It is used in the synthesis of polysaccharides and in the formation of complex carbohydrates. N-Acetyl-L-neuraminic acid has been studied for its potential use as a drug delivery agent due to its ability to inhibit the activity of enzymes such as α-mannosidase, which can lead to tumor metastasis. This compound can be synthesized using methylation, fluorination, and click chemistry, or custom synthesized by ordering specific monosaccharides. N-Acetyl-L-neuraminic acid can also be modified with acetate groups to create an acetylated form for use in chemical analysis or as a substrate for enzymatic reactions.</p>

<p>It is a protected tetrasaccharide intermediate of 3-sialyl-lewis (3'-SLa or sLeA), a tumor-associated carbohydrate antigen.</p>

<p>N-Butyl-1-deoxy-2-fluoronojirimycin is a high purity, custom synthesis, sugar modified, fluorination and glycosylation compound. It is a synthetic compound that has been shown to have potential as a cancer therapeutic agent. It is also used as a reagent in the synthesis of glycosides and oligosaccharides. N-Butyl-1-deoxy-2-fluoronojirimycin's CAS number is 2200278-70-0.</p>

<p>Methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldiphenylsilyl-a-D-mannopyranoside is a synthetic glycosylation product. It has a complex carbohydrate structure and is fluorinated at the O2 position of the sugar. Methylated at the C2 position of the sugar, this saccharide is modified with Click chemistry to attach polysaccharides and oligosaccharides. This product can be custom synthesized in high purity for various purposes.</p>

<p>2-Formylphenyl b-D-glucopyranoside is a phenolic compound that has been shown to have high resistance to transport. It has been shown to possess surface methodology and this property can be used for the delivery of compounds. 2-Formylphenyl b-D-glucopyranoside has also been shown to inhibit plant enzyme activities such as detoxification enzymes and carbohydrate chemistry, which are important in the uptake of natural compounds. In addition, it is able to bind with amines and hydroxyl groups on cells, which may be due to its receptor cell properties. 2-Formylphenyl b-D-glucopyranoside can be synthesized by reacting trifluoroacetic acid with an amine and a hydroxyl group in the presence of glycol ethers or natural compounds.</p>

<p>Phenyl β-D-thiogalactopyranoside is a selective inhibitor of galectin-3, which mediates the growth and metastasis of cancer cells. Phenyl β-D-thiogalactopyranoside has been shown to inhibit the binding of galectin-3 to its receptor on cancer cells, thereby blocking the activation of signaling pathways that promote cell proliferation and survival. The crystalline form can be used as a reagent for the determination of glucose in aqueous solutions.</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>3'-Sialyllactose is found in milk with immunoprotective effects against pathogens in newborns and aids development and maturation of the immune system and gut microbiota. It suppresses adhesion and infectivity of bacteria and viruses, such as influenza viruses, HIV-1 and rotaviruses and inhibits binding of cholera toxin.</p>

<p>Allyl 2,3-anhydro-4,6-O-benzylidene-a-L-mannopyranoside is a glycosylation product of L-mannose. It is a synthetic compound that has been fluorinated and methylated. Allyl 2,3-anhydro-4,6-O-benzylidene-a-L-mannopyranoside is used for the modification of complex carbohydrates. This product has high purity and CAS No., and can be modified with click chemistry.</p>

<p>1-Cyano-1-methylethyl b-D-glucopyranosiduronic acid (1CMEG) is a synthetic monosaccharide that has been modified with fluorination. It is an oligosaccharide, which is a complex carbohydrate made up of many sugar molecules. The CAS number for 1CMEG is 78662-58-5. This product can be custom synthesized to meet customer specifications and needs. It has been shown to have glycosylation and polysaccharide properties, and it can be modified with methylation or sugar binding. This product's purity level is high, making it ideal for use in pharmaceuticals or other applications where purity matters.</p>

<p>Methyl 3,5-di-O-(p-chlorobenzoyl)-2-deoxy-b-D-ribofuranoside is a synthetic oligosaccharide. It has been synthesized by the modification of the glycosylation site on an existing saccharide with a methyl group and fluorination at the 3’ position. This molecule is a monosaccharide with a p-chlorobenzoyl group attached to its 2’ position.</p>

<p>2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl-Fmoc threonine is a glycoside that has been synthesized on a solid phase. The synthesis of this compound has been accomplished by the stepwise addition of Fmoc protected amino acids to the growing peptide chain. Cleavage from the resin and deprotection of the side chains are followed by purification by RP HPLC.</p>

<p>Methyl 2,4-di-O-methyl-b-D-glucopyranoside is a selectively protected glucose glycoside</p>

<p>6-O-(a-D-Galactopyranosyl)-b-D-thioglucopyranose is a complex carbohydrate that is used in the synthesis of oligosaccharides and polysaccharides. It can be modified with methyl groups, glycosylation, or click modification. This product has been fluorinated and is available in high purity.</p>

<p>5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-lyxono-1,4-lactone is an oligosaccharide that is used as a building block for the synthesis of complex carbohydrates. It can be customized to suit your needs. 5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-lyxono-1,4--lactone has been modified with fluorine atom and methyl group to form a glycosylation product. It is available in CAS No. 1044813 -00 -4 and can be synthesized in purity of &gt; 95%.</p>

<p>1,3,5-O-Methylidyne-myo-inositol is a cyclic sugar alcohol, which is naturally derived from various plant sources, including certain fruits and grains. As a stereoisomer of inositol, it represents a specific structural form that contributes to its unique properties and potential biological activities. The compound operates through modulating cellular signaling pathways, particularly those related to phosphoinositide metabolism, influencing intracellular calcium levels, and affecting lipid signaling cascades.This compound is primarily explored for its potential role in neurological health and its capacity to influence insulin signaling pathways. It has been investigated for applications in managing conditions such as polycystic ovary syndrome (PCOS), mood disorders, and neurodegenerative diseases. Due to its intricate involvement in cellular signaling networks, 1,3,5-O-Methylidyne-myo-inositol holds promise in furthering understanding of complex biological processes and for therapeutic development in metabolic and neurological disorders. Research continues to explore its efficacy and mechanisms of action to better establish its role in health and disease.</p>

<p>Heparin is a carbohydrate that is derived from the mucopolysaccharide heparin. It is a complex carbohydrate that consists of a chain of alternating N-acetylglucosamine and glucuronic acid. Heparin is used as an anticoagulant to prevent blood clotting, which may occur due to injury or during surgery. Heparin's use in medicine has been limited by its low solubility and rapid clearance from the body. Recently, it has been modified with a fluorine atom on the sugar ring, which increases their solubility and bioavailability. Click chemistry can be used to attach other molecules to the saccharide ammonium salt in order to modify the properties of heparin. This modification can be done with methyl groups or glycosyl groups, and it can also be done with other sugars such as galactose or glucose.</p>

<p>5-O-(a-D-[6,6'-2H2]Glucopyranosyl)-D-fructopyranose is a custom synthesis carbohydrate that is an oligosaccharide. It is a saccharide with a general formula of C6H10O5. One of its modifications is methylation. This product has been fluorinated and modified with the click reaction to create a glycosylated sugar. 5-O-(a-D-[6,6'-2H2]Glucopyranosyl)-D-fructopyranose is not radioactive and has high purity. It is also a polysaccharide that contains glucose monomers that are linked by glycosidic bonds to form branched chains of 10 or more units. The product has an appearance of white powder, and it can be used as an additive for pharmaceuticals, food products, and cosmetics.</p>

<p>4-Aminophenyl 2-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is a fluorinated mannoside that is modified with methyl and glycosyl groups. It is used as a fluorescent probe for the detection of saccharides in organic solvents. The molecular weight of this compound is 687.</p>