Glicoscienza

5-O-Lauryl-D-xylofuranose is a lipase that can hydrolyze pentoses and hexoses. This enzyme has been shown to be active at temperatures between 0°C and 40°C, with optimal activity at 30°C. 5-O-Lauryl-D-xylofuranose is also thermostable and can be immobilized on silica gel or alumina. It is used in the manufacture of lysine, L-arabinose, and D-xylose. The enzyme catalyzes the reaction by removing a hydroxyl group from the pentoses or hexoses through an ester linkage with a dodecanoate group. The aliphatic chain of 5-O-lauryl dodecanoate is attached to the pentose or hexose molecule in an ester linkage by a thioether bond.

2-Azido-2-deoxy-3,5-O-benzylidene-D-xylono-1,4-lactone is a synthetic sugar that is used in the synthesis of glycosylation, methylation and click modification reactions. It has been shown to be a potential precursor for polysaccharides and fluorinated saccharides. This product can be custom synthesized and is available at high purity.

1,2,3,4,6-Penta-O-acetyl-b-D-glucopyranose, also known as beta-D-glucose pentaacetate, has high chemical stability and long shelf life. This protected form of glucose is a key building block of any chemical synthesis of glucose-containing oligosaccharides or glycoconjugates. In the presence of Lewis acids it can be used as a glycosyl donor to make simple glycosides. In order to perform more complex glycosylations, it can be converted into more reactive donors, such as glycosyl halides or thioglycosides. Beta-D-glucose pentaacetate is also used as a food additive and flavouring agent.

Magnesium L-lactate is a form of magnesium that is found in the human body, and it is often used to treat women with depressive disorders. This drug works by reducing the synthesis of cholesterol and increasing the level of serotonin in the brain. Magnesium L-lactate is not readily absorbed by the body, so it has low bioavailability. It also has an adverse effect on heart rate and cardiac rhythm, so people who have these conditions should avoid using this drug. The particle size of this drug is high, which can lead to low bioavailability.

D-Mannosaminuronic acid is a monosaccharide that has been isolated from the seed of the African plant, Acacia drepanolobium. It is found to be an antigenic component of shigella and related enterobacteria and plays an important role in the biosynthesis of glycolipids. D-Mannosaminuronic acid can be hydrolyzed by acidic enzymes such as lipases, esterases, phosphatases, or proteases. This process may lead to the liberation of fatty acids and sugars. The purified enzyme preparations have been shown to catalyze the synthesis of D-mannosaminuronic acid from mannose and fructose.

Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.

Please enquire for more information about D-Maltose monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

L-Glycero-L-galacto-heptose is a cyclitol that is structurally similar to glycerol and galactose. It has been found in the Australian sea urchin Strongylocentrotus franciscanus. L-Glycero-L-galacto-heptose can be synthesized by reacting methyl glycosides with calcium ions. This reaction produces an electrophoretic mobility that is greater than that of glycerol, which may be due to the greater degree of hydrogen bonding between methyl glycosides and calcium ions. The presence of hydroxyl groups on the sugar residue allows for the formation of hydrogen bonds with neighboring molecules. These interactions lead to a conformation that is different from other cyclitols, such as D-glycero-D-galactopyranose, which has no hydroxyl group on its sugar residue.

Pullulan is a polysaccharide that is made up of D-glucose units linked in a beta-1,6 configuration. Pullulan has been used as a model system to study the molecular mechanisms of intramolecular hydrogen transfer reactions. The process optimization of pullulan production was studied using skin cells and structural analysis. This polymer is also used in food hydrocolloids, where it can be used to control the phase transition temperature. Pullulan has also been shown to have anti-angiogenic effects on liver cells and water vapor absorption properties.

4-Aminophenyl b-D-glucuronide sodium is a glycosylation reagent used in the synthesis of complex carbohydrates, polysaccharides and oligosaccharides.

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

2-Azido-2-deoxy-3,5-di-O-tert-butyldiphenylsilyl-D-ribono-1,4-lactone is a high purity custom synthesis sugar with a click modification. The chemical formula for this compound is C20H28N4O14 and its molecular weight is 524.329 g/mol. 2A2D3BTSL has been fluorinated, glycosylated, and methylated. It is an oligosaccharide with 6 monosaccharides and a complex carbohydrate that has a saccharide in the center of it.

1,4-Anhydro-D-glucitol is a compound that belongs to the group of monosaccharides and has biological properties. It has also been used in the production of acetate extracts from fetal bovine erythrocytes. The ester linkages are formed between 1,4-anhydro-D-glucitol and sodium salt by reaction with acetic anhydride. The reaction mechanism has been studied in detail, and it was found that hydroxyl groups on the molecule react with sodium ions to form an ester linkage. This compound is toxicologically safe at high doses, but can become toxic at lower doses due to its acid formation potential.

2-Azido-2-deoxy-2-C-methyl-D-ribono-1,5-lactone is a custom synthesized carbohydrate. It is an oligosaccharide that is modified by methylation and glycosylation. The carbohydrate has been fluorinated to provide the desired properties of this product. 2-Azido-2-deoxy-2-C-methyl-Dribono1,5 -lactone is a high purity product that is synthesized in a controlled environment with strict quality control measures. It has been synthesized using Click chemistry and is available for purchase in bulk quantities.

6-O-Benzyl-1-(-)-carboxymenthyl-2,3:4,5-di-O-cyclohexylidene-L-myo-inositol is a synthetic oligosaccharide with the chemical formula C9H14FNO5. It is a monosaccharide composed of a single sugar unit, inositol, which has been modified with benzyl groups on the 6th and 1st positions of the inositol ring. This compound is used as an intermediate in the synthesis of other saccharides.

Tri-O-acetyl-4-pentulosonic acid methyl ester is a high purity, custom synthesis sugar that has been modified by click chemistry. It is fluorinated, glycosylated and synthetically modified. The chemical name for this product is 3'-O-Acetyl-4'-O-(2,3,5,6-tetrafluoro)pentylosonic acid methyl ester. Tri-O-acetyl-4-pentulosonic acid methyl ester is a saccharide that has the CAS No. 108595-14-8 and has been shown to be useful in the synthesis of oligosaccharides and monosaccharides.

1,6-b-Galactotriose is a glycosylation product of 1,6-galactose. It is a complex carbohydrate that is found in nature and can be used for modification of saccharides, sugar, oligosaccharides, or other monosaccharides. The product is also used as a building block for the synthesis of custom polysaccharides. It can be fluorinated or methylated and click modified to produce a desired saccharide structure.

(1S) -1- [(2S, 3S,4R) -4-Hydroxymethyl-3- hydroxy- N-methyl-1- azetidinyl] -1, 2- ethanediol is a synthetic sugar that can be used as a glycosylation or methylation agent. It is a white powder with a molecular weight of 342. The purity of this product is > 98%. This product has CAS No. 517862-65-8.

Ribulose 5-phosphate sodium is a chemical that can be used to inhibit the enzyme ribulose phosphate reductase. Ribulose 5-phosphate sodium has been shown to inhibit glycolaldehyde production in the chloroplasts of plants, effectively reducing the amount of carbon dioxide produced. This chemical has also been shown to have an inhibitory effect on other enzymes involved in carbon fixation and assimilation. The effectiveness of this chemical is dependent on the specific plant species and environmental conditions.

Chondroitin disaccharide 6S sodium salt is a synthetic, fluorinated, oligosaccharide that has been custom synthesized and glycosylated. It is a sugar-based compound with a high purity and excellent solubility in water. It was synthesized by click modification of the sugar monomer with an amine group at the reducing end. The chondroitin disaccharide 6S sodium salt was further modified with methylation to yield a product with a higher purity.

Reference compound for metabolites of the pentosephosphate pathway

Applications N,N-[Iminobis(trimethylene)]bis-D-gluconamide (cas# 86303-20-0) is a compound useful in organic synthesis.

Shortest chain oligosaccharide that can be classified as a maltodextrin. A component of liquid glucose (a commercial sweetener composed of glucose, maltose, maltotriose and maltotetrose).

3-O-Acetyl-1,2:5,6-di-O-isopropylidene-a-D-galactofuranose is a synthetic modified oligosaccharide with a molecular weight of 591.3 g/mol. It has been shown to inhibit the growth of various bacterial strains in the lab and can be used as an antibiotic for bacterial infections. 3-O-Acetyl-1,2:5,6-di-O-isopropylidene galactofuranose is a monosaccharide composed of two acetyl groups and one isopropylidene group. Its glycosylation and methylation patterns are also known.

D-ribulose-5-phosphate sodium is a nucleotide sugar that is one of the ribonucleotides, which are fundamental components of RNA. D-ribulose 5-phosphate sodium has been shown to be an intermediate in the metabolism of ribulose and catalyzes the oxidation of d-arabinose. This enzyme also catalyses the synthesis of fatty acids and participates in reactions involving glycerolipids and phospholipids. The reaction mechanism involves a double displacement with simultaneous attack by a water molecule on C2' and C3'. When deuterium is present, it affects the rate of these reactions in a way that depends on the orientation of the substrate to the enzyme.

1,5-α-L-Arabinohexaose is a carbohydrate. It is a nonreducing sugar that can be found in plants. 1,5-α-L-Arabinohexaose has an optimum pH of 5 and an ethanol concentration of 0.02%. The enzyme form of 1,5-α-L-Arabinohexaose is α-(1→6)-glycosidase. This enzyme hydrolyzes the α-(1→6) glycosidic bond between two glucose residues in a polysaccharide chain to produce β-(1→4) bonds. It also hydrolyzes the β-(1→4) glycosidic bond between two galactose residues to produce β-(1→2) bonds and oxidizes the terminal carbon atom to produce aldehyde products.
A structural analysis of this carbohydrate was conducted using marine microorganisms and it was found that they contain galacturonic acid and sugar residues

4-Deoxy-D-glucose is a sugar that is synthesized by the condensation of two molecules of erythrose. It has been shown to be an efficient donor substrate for nucleophilic attack, which can lead to the synthesis of glycosides and other natural products. 4-Deoxy-D-glucose is also a competitive inhibitor of uridine diphosphate (UDP) glucose, which is an enzyme involved in the biosynthesis of UDP sugars and glycoproteins. The concentration of 4-deoxy-D-glucose affects its catalytic mechanism, as it acts as a competitive inhibitor at high concentrations. Molecular modeling has revealed that this molecule adopts a chair conformation with significant solvent exposure.

1,4-β-D-Glucosyl-D-mannobiose is a specialized carbohydrate substrate, which is derived from complex polysaccharides typically found in plant cell walls. It acts as a substrate for endo-1,4-β-mannanase, an enzyme that cleaves specific glycosidic bonds within mannans. This substrate facilitates the investigation of enzymatic activity by allowing the measurement of endo-1,4-β-mannanase efficiency and specificity under controlled conditions.In biochemical enzyme assays, 1,4-β-D-Glucosyl-D-mannobiose serves as a critical component for quantifying mannanase activity. It enables researchers to study the enzyme's role in various biological processes, including polysaccharide degradation. Additionally, this product is invaluable in in vitro diagnostic analyses where precise enzyme activity assessment is crucial for understanding pathological states or the functionality of industrial enzyme preparations. Its applications extend to biotechnology research, where it aids in the formulation of enzyme-based solutions and optimization of enzymatic reactions in diverse biological and industrial contexts.

Please enquire for more information about Sodium carboxymethyl cellulose, viscosity 50-200 cps including the price, delivery time and more detailed product information at the technical inquiry form on this page

D-glucose 6-phosphate is an intermediate in the hexose monophosphate shunt pathway. It is formed by the enzyme phosphoglucomutase from D-glucose 1-phosphate and UTP. D-glucose 6-phosphate is also an important intermediate in glycolysis. The conversion of D-glucose 6-phosphate to glucose 1,6-bisphosphate occurs through a series of reactions catalyzed by enzymes that are sensitive to inhibition by magnesium ions. These reactions include the phosphofructokinase, hexokinase, and pyruvate kinase reactions. The accumulation of glucose 6-phosphate leads to increased levels of lactate production and decreased levels of ATP production. This may be due to its ability to inhibit monoamine reuptake, which would lead to decreased synthesis of dopamine and serotonin.

D-Arabino-5-hexulosonic acid is an intermediate in the pentose phosphate pathway. It is a component of the hexuronate, which is an important precursor for galactitol, 6-phosphate, and acid dehydrogenase. D-Arabino-5-hexulosonic acid is also an important intermediate in the glycolytic pathway for ATP production. The gene product has been shown to be involved in aerobic glycolysis, which is utilized by Staphylococcus aureus to produce energy from glucose fermentation. D-Arabino-5-hexulosonic acid plays a role in ion exchange and mitochondrial metabolism as well.

D-Glucose 6-phosphate, disodium salt is an antibiotic that is used to treat gram-negative bacterial infections. It binds to the bacterial ribosome and inhibits protein synthesis, which leads to cell death by inhibiting the production of proteins vital for cell division. This drug has been shown to be active against a wide range of bacteria, including resistant strains such as Escherichia coli and Salmonella typhimurium. D-Glucose 6-phosphate, disodium salt also has anti-inflammatory properties and can be used as an anti-bacterial agent in the treatment of typhoid fever.

Dyed and soluble azo-xyloglucan (tamarind) is used for the measurement of enzyme activity, research, biochemical enzyme assays and in vitro diagnostic analysis.  It is a soluble chromogenic substrate for the assaying of endo-cellulase.

Please enquire for more information about 1,5-α-L-Arabinooctaose including the price, delivery time and more detailed product information at the technical inquiry form on this page

Glucose pentaacetate is a form of glucose that reacts with boron trifluoride etherate to produce anomers. This process can be used to synthesize the anomeric form of glucose, which is important for the biosynthesis of glycosides. Glucose pentaacetate has been shown to react with nitrate and trifluoride, forming conjugates with aluminum and chloride. The catalytic stereocontrol of this reaction allows for the production of disaccharides without hydrogen chloride or formylation.

2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-galactopyranose is a fluorinated complex carbohydrate that has been modified by methylation and acetylation. This product is a custom synthesis that has not been previously described in the scientific literature. It is synthesized from 2, 3, 4, 6 tetraacetyl alpha D galactopyranoside and 2 deoxy alpha D galactopyranose. The chemical properties of this compound are similar to those of other complex carbohydrates such as glycogen and heparin.

D-Xylulose 5-phosphate sodium salt is a synthetic monosaccharide that can be used in the synthesis of oligosaccharides, polysaccharides, and complex carbohydrates. It is also used in glycosylation reactions. D-Xylulose 5-phosphate sodium salt has been fluorinated to provide better stability and solubility. The compound has a molecular weight of 206.06 g/mol and a CAS number of 105931-44-0. This product is available for custom synthesis upon request.

4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.

α-6⁴-6³-Di-galactosyl-mannopentaose is a specialized oligosaccharide, which is a type of complex carbohydrate. This compound is derived from natural plant sources and its structure comprises a mannopentaose core linked with two galactose units. The mode of action involves specific interactions with gut microbiota, where it selectively enriches beneficial bacterial populations, such as Bifidobacteria and Lactobacilli. These interactions occur by serving as a fermentation substrate, promoting the growth of microbes that confer beneficial effects on host health.

3'-a-Sialyl-N-acetyllactosamine sodium salt is a high purity, custom synthesis sugar. It has been modified with fluorination, glycosylation, and methylation to provide the desired properties. This product is also available in other forms such as monosaccharide and saccharide. 3'-a-Sialyl-N-acetyllactosamine sodium salt can be used in various applications including Click modification, fluoroamination, glycosylation, carbonylation and methylation. CAS No. 350697-53-9

Methyl D-arabinofuranoside is an antimycobacterial agent that inhibits the synthesis of mycolic acids, which are important components of the cell wall of Mycobacterium tuberculosis. Methyl D-arabinofuranoside has been shown to be active against drug-resistant strains and has been well tolerated by animals. This compound can be synthesized from 2,4-dichlorophenylacetic acid and arabinose in two steps. The first step involves a three-component condensation reaction with sodium hydroxide, hydrochloric acid, and 2,4-dichlorophenylacetic acid. The second step is a nucleophilic attack on the pyran ring of methyl D-arabinofuranoside with hypophosphorous acid. Methyl D-arabinofuranoside can also be prepared by reacting sodium nitrosobenzene with sodium benzene sulfinate in alcoholic solution

Benzyl 2,3-O-isopropylidene-a-D-mannofuranoside is a fluorinated monosaccharide that is synthesized using glycosylation and polysaccharide modification. This product has a CAS number of 20689-03-6 and can be used for complex carbohydrate synthesis. It has been shown to have high purity.