Antimicotici
Gli antifungini sono composti specificamente progettati per fermare, prevenire ed eliminare la crescita dei funghi. In questa categoria, troverete una vasta gamma di agenti antifungini essenziali per la ricerca e le applicazioni terapeutiche. Questi composti sono cruciali nel trattamento delle infezioni fungine e nella prevenzione delle loro recidive, rendendoli strumenti vitali sia in ambito medico che agricolo. Ricercatori e professionisti della salute possono esplorare numerosi antifungini per comprendere i loro meccanismi, ottimizzarne l'efficacia e sviluppare nuovi trattamenti per combattere ceppi fungini resistenti. L'ampia selezione di antifungini supporta i continui progressi nella ricerca sui funghi e lo sviluppo di terapie antifungine efficaci.
Trovati 837 prodotti di "Antimicotici"
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Micafungin sodium - Bio-X ™
CAS:<p>Micafungin, as one of three echinocandina, has been proven to be a successful antifungal therapeutic in treating general Candida fungus infections. The treatment of immunocompromised patients is particularly important as Candida infections cause high mortality rates in patients in intensive care units, receiving chemotherapy, or stem cell transplants. This product acts as an anti-fungal by inhibiting the 1,3-beta-D-glucan synthase enzyme. As a result the production of 1,3-beta-D-glucan, which is crucial to the fungal cell wall, is hindered. Thus, the fungal cell wall loses integrity allowing for osmotic instability and cell lysis to occur.</p>Formula:C56H71N9O23S•NaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:1,293.27 g/molVoriconazole - Bio-X ™
CAS:<p>Voriconazole is a synthetic, lipophilic molecule that is used in the treatment of fungal infections. Voriconazole binds to ergosterol which is the major sterol in the cell wall of fungi and inhibits its synthesis, leading to cell death. This drug binds to the enzyme 14α-demethylase allowing the conversion of lanosterol into ergosterol. As a result, this binding leads to the inhibition of ergosterol synthesis, as well as other sterols that are necessary for fungal growth (e.g., squalene).</p>Formula:C16H14F3N5OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:349.31 g/molPosaconazole - Form III
CAS:<p>Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for the synthesis of the fungal cell wall component, ergosterol. This demethylase enzyme synthesizes ergosterol through converting lanosterol to ergosterol. Therefore Posaconazole prevents the formation of fungal cell walls with the appropriate membrane permeability thus leading to fungal cell lysis. Posaconazole can be used as an antifungal drug to treat opportunistic fungal infections in immunocompromised individuals such as HIV patients. Moreover it is shown to inflict its inhibitory activity against common pathogenic fungus such as Candida and Aspergillus species but also Mucorales and some Fusarium species, which are less common.</p>Formula:C37H42F2N8O4Purezza:Min. 95%Peso molecolare:700.78 g/molIsavuconazole
CAS:<p>Anti-fungal; lanosterol 14α-demethylase inhibitor</p>Formula:C22H17F2N5OSPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:437.47 g/mol2-Methyl-4-isothiazolin-3-one HCl
CAS:Prodotto controllato<p>2-Methyl-4-isothiazolin-3-one HCl , also known as MIT hydrochloride is often used as a preservative in personal care products and other industrial applications. The product has shown to act as an antimicrobial and antifungal agent.</p>Formula:C4H5NOS·HClPurezza:Min. 95%Colore e forma:White Slightly Yellow PowderPeso molecolare:151.62 g/molLiranaftate
CAS:<p>Inhibitor of squalene epoxidase</p>Formula:C18H20N2O2SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:328.43 g/molLucimycin
CAS:<p>Lucimycin is an antibiotic, which is derived from the fermentation of specific Streptomyces bacterial strains. This compound exerts its antibacterial effects by binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis and effectively halting bacterial growth. Lucimycin is particularly effective against Gram-positive bacteria and some Gram-negative species, making it a valuable tool in both clinical and research settings.</p>Formula:C36H53NO13Purezza:Min. 95%Peso molecolare:707.8 g/molCaspofungin acetate
CAS:Prodotto controllato<p>Inhibitor of glucan synthase; antifungal compound</p>Formula:C52H88N10O15·2C2H4O2Purezza:Min. 90 Area-%Colore e forma:PowderPeso molecolare:1,213.42 g/molCiclopirox
CAS:<p>Pan-histone demethylase inhibitor; anti-fungal; iron-chelator</p>Formula:C12H17NO2Colore e forma:White PowderPeso molecolare:207.27 g/molEpoxiconazole
CAS:<p>Fungicide</p>Formula:C17H13ClFN3OPurezza:Min. 98 Area-%Colore e forma:White Off-White PowderPeso molecolare:329.76 g/molAlbendazole
CAS:<p>Anthelmintic; inhibitor of tubulin polymerization</p>Formula:C12H15N3O2SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:265.33 g/molFluconazole - Bio-X ™
CAS:<p>Fluconazole is an antifungal drug used to treat a wide range of fungal infections. Fluconazole is a cytochrome demethylase system inhibitor that acts by interfering with β-glucan biosynthesis. It has been shown to be effective in treating candidemia, a life-threatening form of candidiasis caused by the fungus Candida albicans. Fluconazole seems to be more effective than amphotericin B in treating some isolates of C. albicans, making it a valuable tool in the fight against this deadly fungal infection, although due to the increase of antimicrobial resistance, fluconazole has been studied in combination with other drugs (e.g. farnesol).</p>Formula:C13H12F2N6OPurezza:(%) Min. 95%Colore e forma:PowderPeso molecolare:306.27 g/molPosaconazole - Bio-X ™
CAS:<p>Posaconazole is a triazole antifungal agent that inhibits the 14-alpha demethylase enzyme. This drug prevents the formation of fungal cell walls thus leading to fungal cell lysis. Posaconazole is shown to inflict its inhibitory activity against common pathogenic fungus such as Candida and Aspergillus species in severely immunocompromised patients.</p>Formula:C37H42F2N8O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:700.78 g/molClotrimazole
CAS:<p>Clotrimazole is an azole antifungal medication with action on fungal cell membrane disruption and is used for treating fungal infections like athlete's foot, ringworm, and vaginal yeast infections.</p>Formula:C22H17ClN2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:344.84 g/molAnidulafungin
CAS:<p>Anti-fungal; glucan synthase inhibitor</p>Formula:C58H73N7O17Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:1,140.24 g/molCaspofungin acetate - Bio-X ™
CAS:Prodotto controllato<p>Caspofungin is an echinocandin that belongs to the class of antifungal agents. It is used to treat Aspergillus and Candida infections. It works by inhibiting the synthesis of beta-(1,3)-D-glucan, an essential component of the cell wall of Aspergillus species and Candida species.</p>Formula:C52H88N10O15·2C2H4O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:1,213.42 g/molIsoconazole
CAS:<p>Isoconazole is an azole antifungal compound with a mode of action that inhibits ergosterol synthesis, disrupting fungal cell membranes. It is used for treating fungal infections of the skin and nails.</p>Formula:C18H14Cl4N2OPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:416.13 g/molPosaconazole
CAS:<p>Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for the synthesis of the fungal cell wall component, ergosterol. This demethylase enzyme synthesizes ergosterol through converting lanosterol to ergosterol. Therefore Posaconazole prevents the formation of fungal cell walls with the appropriate membrane permeability thus leading to fungal cell lysis. Posaconazole can be used as an antifungal drug to treat opportunistic fungal infections in immunocompromised individuals such as HIV patients. Moreover it is shown to inflict its inhibitory activity against common pathogenic fungus such as Candida and Aspergillus species but also Mucorales and some Fusarium species, which are less common.</p>Formula:C37H42F2N8O4Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:700.78 g/molTerconazole
CAS:<p>Terconazole is an azole antifungal agent with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for treating vaginal yeast infections.</p>Formula:C26H31Cl2N5O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:532.46 g/molKetoconazole
CAS:<p>Ketoconazole is an azole antifungal compound with a mode of action that inhibits ergosterol synthesis, disrupting fungal cell membranes. It is used for treating fungal infections of the skin and scalp.</p>Formula:C26H28Cl2N4O4Colore e forma:White PowderPeso molecolare:531.43 g/molOxiconazole nitrate - Bio-X ™
CAS:<p>Oxiconazole is an anti-fungal agent that is used for the treatment of various dermatophyte infections. It can be used to treat athlete’s foot, ringworm and jock itch. This drug inhibits ergosterol biosynthesis and acts to destabilize the fungal cytochrome enzyme P450 51. Additionally, this drug has shown to inhibit DNA synthesis and suppress concentrations of ATP.</p>Formula:C18H14Cl4N4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:492.14 g/molAtovaquone - Bio-X ™
CAS:<p>Atovaquone is an antimicrobial drug that is used for the treatment of Pneumocystis jirovecii pneumonia. This drug is an analog of ubiquinone and has good in vitro activity against Toxoplasma gondii.</p>Formula:C22H19ClO3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:366.84 g/molFengycin A analogue
CAS:<p>Fengycin A analogue is an antifungal lipopeptide, which is a cyclic compound derived from microbial sources, specifically produced by Bacillus subtilis strains. It functions primarily by disrupting the cell membranes of pathogenic fungi, leading to altered membrane permeability and subsequent cell death. The unique structure of fengycin allows it to interact with membrane lipids, compromising membrane integrity and inhibiting fungal growth.</p>Efinaconazole
CAS:<p>Efinaconazole is a triazole antifungal agent with action on fungal 14α-demethylase to inhibit ergosterol synthesis and is used for treating onychomycosis (fungal nail infections).</p>Formula:C18H22F2N4OPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:348.39 g/molFilipin
CAS:<p>Filipin is a polyene macrolide antifungal agent with action on cholesterol in cell membranes and is used for histochemical staining and research on cholesterol metabolism.</p>Purezza:Min. 97 Area-%Colore e forma:Yellow PowderIpconazole
CAS:<p>Ipconazole is a fungicide with a mode of action that inhibits ergosterol biosynthesis, disrupting fungal cell membranes. It is used for seed treatment to protect crops like cereals and vegetables from fungal diseases. It's sold as a mixture of two isomers.</p>Formula:C18H24ClN3OPurezza:Min. 95%Peso molecolare:333.86 g/molPosaconazole - Form I
CAS:<p>Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for the synthesis of the fungal cell wall component, ergosterol. This demethylase enzyme synthesizes ergosterol through converting lanosterol to ergosterol. Therefore Posaconazole prevents the formation of fungal cell walls with the appropriate membrane permeability thus leading to fungal cell lysis. Posaconazole can be used as an antifungal drug to treat opportunistic fungal infections in immunocompromised individuals such as HIV patients. Moreover it is shown to inflict its inhibitory activity against common pathogenic fungus such as Candida and Aspergillus species but also Mucorales and some Fusarium species, which are less common.</p>Formula:C37H42F2N8O4Purezza:Min. 95%Peso molecolare:700.78 g/molFR 901379 sodium
CAS:<p>Impurity of Micafungin; anti-fungal</p>Formula:C51H81N8O21S·NaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:1,197.29 g/molTerbinafine HCl - Bio-X ™
CAS:<p>Terbinafine is an antifungal drug that is used in the treatment of dermatophyte infections of the toenails and fingernails. Terbinafine also treats other skin infections. This drug works by inhibiting ergosterol synthesis which in return inhibits fungal squalene monooxygenase. This results in a disruption of fungal cell wall synthesis.</p>Formula:C21H25N•HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:327.89 g/molFenticonazole nitrate
CAS:<p>Fenticonazole nitrate is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal infections like vaginal thrush and athlete's foot.</p>Formula:C24H20Cl2N2OS·HNO3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:518.41 g/molItraconazole - Bio-X ™
CAS:<p>Itraconazole is an anti-fungal drug that inhibits the synthesis of ergosterol, a component of the fungal cell membrane. Itraconazole is in a class of antifungals called triazoles. The drug binds to ergosterol in the fungal cell membrane and prevents it from being inserted into the membrane. This decreases the permeability of the plasma membrane, causing leakage of cellular contents. Additionally, it has been shown to have a glucose-lowering effect in the treatment of acute leukaemia and may be used for research in aiding to diagnose hematopoietic stem cell or leukaemia.</p>Formula:C35H38Cl2N8O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:705.63 g/molTerbinafine hydrochloride
CAS:<p>Activator of the two-pore domain potassium channel TASK3</p>Formula:C21H26ClNPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:327.89 g/molMiconazole nitrate - Bio-X ™
CAS:<p>Miconazole is an antifungal drug that is used for the treatment of fungal infections. This drug has broad-spectrum activity and works by inhibiting fungal CYP450 14α-lanosterol demethylase activity. This leads to altered ergosterol production and an impaired cell membrane.</p>Formula:C18H14Cl4N2O•HNO3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:479.14 g/molButenafine hydrochloride
CAS:<p>Butenafine hydrochloride is an antifungal agent and is used for the treatment of fungal infections. It inhibits the synthesis of ergosterol, a key component of fungal cell membranes.</p>Formula:C23H28ClNPurezza:Min. 95%Colore e forma:PowderPeso molecolare:353.93 g/molPafuramidine
CAS:<p>Pafuramidine is an antiprotozoal prodrug with action on protozoal DNA synthesis inhibition and is used for treating African sleeping sickness and Pneumocystis pneumonia.</p>Formula:C20H20N4O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:364.4 g/molCiclopirox olamine - Bio-X ™
CAS:<p>Ciclopirox is a broad-spectrum antifungal agent that is used to treat onychomycosis of fingernails and toenails in immunocomprised patients. Ciclopirox has been shown to work by binding to polyvalent metal cations such Al3+ and Fe3+. These cations interfere with cellular processes including mitochondrial electron transport and energy synthesis by inhibiting numerous enzymes, including cytochromes. Additionally, the plasma membrane of fungi appears to be altered by ciclopirox as well, leading to the disorder of internal structures.</p>Formula:C12H17NO2•C2H7NOPurezza:Min. 95%Colore e forma:PowderPeso molecolare:268.35 g/molBifonazole - Bio-X ™
CAS:<p>Bifonazole is an antifungal drug that is used for the treatment of fungal infections. This drug inhibits the production of ergosterol and destabilizes the fungal cytochrome p450 51 enzyme.</p>Formula:C22H18N2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:310.39 g/molDelafloxacin
CAS:<p>Delafloxacin is a fluoroquinolone antibiotic with action on bacterial DNA gyrase and topoisomerase IV and is used for treating acute bacterial skin and skin structure infections.</p>Formula:C18H12ClF3N4O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:440.76 g/mol2-Methyl-4-isothiazolin-3-one - 50% aqueous solution
CAS:Prodotto controllato<p>2-Methyl-4-isothiazolin-3-one or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products. It is also used in industrial applications as a preservative and antifouling agent.</p>Formula:C4H5NOSPurezza:(%) Reported (%)Colore e forma:Colorless Clear LiquidPeso molecolare:115.15 g/molAmphotericin A
CAS:<p>Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.</p>Formula:C47H75NO17Purezza:Min. 95%Peso molecolare:926.09 g/molExalamide
CAS:<p>Exalamide is an arenecarboxamide antifungal agent with action on fungal growth inhibition and is used for research on fungal infections.</p>Formula:C13H19NO2Purezza:Min. 95%Peso molecolare:221.3 g/molButoconazole nitrate
CAS:<p>Butoconazole nitrate is an antifungal agent and is used for the treatment of vaginal yeast infections. It inhibits the synthesis of ergosterol, disrupting the fungal cell membrane.</p>Formula:C19H18Cl3N3O3SPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:474.79 g/molFolpet-d4
CAS:<p>Folpet-d4 is a deuterated compound of Folpet. Folpet has a CAS number of 133-07-3. Folpet,a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.</p>Formula:C9D4H0Cl3NO2SColore e forma:SolidPeso molecolare:300.58o-Tolylglyoxylic Acid Methyl Ester
CAS:Prodotto controllato<p>Applications o-Tolylglyoxylic Acid Methyl Ester is an intermediate in the synthesis of Trifloxystrobin (T778900), a broad-spectrum foliar fungicide used in plant protection.<br></p>Formula:C26H33NO6Colore e forma:NeatPeso molecolare:455.5434-(4-Chlorophenyl)-1-(4H-1,2,4-triazol-4-yl)butan-2-one
CAS:Prodotto controllato<p>Applications 4-(4-Chlorophenyl)-1-(4H-1,2,4-triazol-4-yl)butan-2-one is an impurity in the synthesis of 5-(4-Chlorophenyl)-2,2-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)-1,3-pentanediol (C377885), which is a hydroxy tebuconazole conjugate. Tebuconazole (T013000) is an ergosterol biosynthesis inhibitor. Fungicide.<br>References Gent, D., et al.: Plant Dis., 87, 591 (2003), Wang, C., et al.: Pestic. Biochem. Physiol., 87, 1 (2007),<br></p>Formula:C12H12ClN3OColore e forma:NeatPeso molecolare:249.7R406
CAS:<p>Applications R406 is a potent Syk inhibitor which affects Dectin-1-mediated signalling in mammilian cells. R406 thus acts an anti-fungal agent. Also a potential anti-leukemia agent, through modulation of sphingosine-1 phosphate receptor 1 (S1PR1).<br>References Borge, M. et al.: J. Immunol., 193, 3165 (2014); Kimura, Y. et al.: J. Biol. Chem., 289, 31565 (2014);<br></p>Formula:C22H23FN6O5·(C6H6O3S)Colore e forma:Light BrownPeso molecolare:470.45 + (158.18)1-(4-Chloro-3-methoxyphenyl)-4,4-dimethylpentan-3-one
CAS:Prodotto controllatoFormula:C14H19ClO2Colore e forma:NeatPeso molecolare:254.75(R)-4-Amino-1,1,3-trimethylindane D-Tartaric Acid
CAS:Prodotto controllatoFormula:C12H17N·C4H6O6Colore e forma:NeatPeso molecolare:175.27 + 150.093-Methyl-3-phenylamino-1-butyne
CAS:Prodotto controllato<p>Applications 3-Methyl-3-phenylamino-1-butyne is an intermediate in the synthesis of Endophenazine A which is a new phenazine antibiotic isolated from the arthropod associated endosymbiont Streptomyces anulatus and shows antimicrobial activities against Gram-positive bacteria and some filamentous fungi, and herbicidal activity against Lemna minor (duckweed).<br>References Gebhardt, K., et al.: J. Antibiot., 55, 794 (2002)<br></p>Formula:C11H13NColore e forma:NeatPeso molecolare:159.23
