Flavonoidi

R,S-Equol is a racemic mixture, classified as an isoflavandiol compound, which is synthesized from the metabolism of soy isoflavones, specifically daidzein, by gut microbiota. It acts as a selective estrogen receptor modulator (SERM) with a preference for estrogen receptor beta (ERβ). This compound demonstrates the ability to bind these receptors, mimicking the action of estrogen, but with selective modulation and lower activity than natural estrogen.

<p>Vitexin is a naturally occurring flavonoid, which is primarily extracted from plants such as the passionflower (Passiflora) and hawthorn (Crataegus). This bioactive compound is classified under the category of C-glycosyl flavones and is characterized by its unique structural features, including a glycosidic linkage that contributes to its stability and bioavailability.</p>

Apigenin-7-diglucuronide is a naturally occurring flavonoid derivative compound, which is primarily derived from various plant sources such as parsley, chamomile, and celery. It represents a glucuronidation product of apigenin, a process involving enzymatic attachment of glucuronic acid to the molecule, enhancing its water solubility and bioavailability.

<p>Liquiritin apioside is a flavonoid glycoside, which is predominantly derived from the root of Glycyrrhiza uralensis, commonly known as licorice. This compound acts primarily through its anti-inflammatory and antioxidant properties, which involve the modulation of various cellular pathways. Specifically, it influences the activity of inflammatory cytokines and oxidative stress markers, potentially inhibiting pathways such as nuclear factor-kappa B (NF-κB).</p>

<p>2',3'-Dimethoxy-3-hydroxyflavone is a specialized flavonoid compound, which is synthesized and not typically found in natural sources. As a flavonoid derivative, this compound is formed through chemical modification of naturally occurring flavones, a class of polyphenolic compounds recognized for their diverse biological activities. With a structure characterized by methoxy and hydroxyl groups, this compound exhibits unique interactions at the molecular level.</p>

<p>Ononin is an isoflavonoid glycoside, which is derived from various plant sources, including species of the genus Ononis. It is primarily sourced from the roots and aerial parts of these plants, where it occurs as a natural constituent. The mode of action of Ononin involves its hydrolysis to form its aglycone, formononetin, which is known to exhibit estrogenic activity due to its structural similarity to estrogenic compounds.</p>

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<p>Wogonoside is a naturally occurring flavonoid glycoside, which is derived primarily from Scutellaria baicalensis, a traditional Chinese medicinal herb. It functions through its ability to modulate various biochemical pathways, demonstrating significant anti-inflammatory and anticancer properties. Wogonoside exerts its effects by inhibiting key enzymes and signaling pathways involved in inflammation, such as nuclear factor-kappa B (NF-κB), and inducing apoptosis in cancer cells through the activation of caspases and modulation of apoptosis-related proteins.</p>

Quercetin 3-O-b-D-glucuronide is a flavonoid compound, which is a metabolite of quercetin, found in various fruits and vegetables. This compound, specifically a glucuronide conjugate of quercetin, is derived from plant sources such as apples, onions, and berries. It is formed through phase II metabolism where quercetin is glucuronidated by the enzyme UDP-glucuronosyltransferase.

Neoliquiritin is a flavonoid compound, which is derived from the root of the licorice plant, Glycyrrhiza glabra. This compound exhibits significant antioxidant properties through its ability to scavenge free radicals, thereby reducing oxidative stress within biological systems. Neoliquiritin is primarily utilized in scientific research to explore its potential therapeutic effects, particularly its anti-inflammatory and antioxidant activities. Its mode of action involves modulation of various cellular signaling pathways associated with inflammation and oxidative damage, making it a subject of interest in studies related to chronic diseases and skin conditions. Researchers investigate its potential in mitigating oxidative stress-related cellular damage, offering insights into its possible applications in pharmacology and dermatology.

<p>Schaftoside is a naturally occurring flavonoid glycoside, which is derived from a variety of plant sources, particularly within the Leguminosae and Poaceae families. As a compound, it features a structural integration of apigenin linked to two units of glucose, establishing its classification within the group of C-glycosyl flavonoids. Its mode of action involves interactions with various molecular pathways, implying antioxidant and anti-inflammatory effects. This is attributed to its capacity to scavenge free radicals and modulate signal transduction processes involving cytokines and transcription factors.</p>

<p>Eupatorin 5-methyl ether is a bioactive compound, which is a naturally occurring flavonoid found in certain plant species. This compound is derived from various plants, including those in the Asteraceae family. Eupatorin 5-methyl ether functions primarily through modulating various biochemical pathways, exhibiting anti-inflammatory, antioxidant, and anticancer activities.</p>

<p>4'-Hydroxyflavanone is a naturally occurring flavonoid compound, which is derived from plant sources, particularly citrus fruits and other types of vegetation. The compound is characterized by its phenolic structure, which plays a significant role in its biological activity. 4'-Hydroxyflavanone exhibits its mode of action primarily through antioxidant activity, which involves scavenging reactive oxygen species and thus protecting cells from oxidative stress.</p>

<p>8-O-Methylretusin is a naturally occurring O-methylated flavonoid, which is derived from various plant sources. This compound is notable for its potential bioactive properties, including antioxidative, anti-inflammatory, and anticancer activities. The mode of action of 8-O-Methylretusin primarily involves modulation of cellular signaling pathways, such as the inhibition of reactive oxygen species and modulation of key transcription factors that regulate inflammatory and apoptotic processes.</p>

3,7,2',4',5'-Pentamethoxyflavone is a naturally occurring flavonoid compound, which is a type of polyphenolic product. It is commonly found in various plant species, serving potential protective and adaptive functions within these organisms. The mode of action of 3,7,2',4',5'-Pentamethoxyflavone involves interaction with multiple biological pathways, including modulation of enzyme activity and influence over cellular signaling pathways. Its biochemical interactions often result in antioxidant, anti-inflammatory, and possible antiproliferative effects.

<p>3,7,4'-Trihydroxyflavone is a flavonoid compound, which is a naturally occurring polyphenolic phytochemical. These compounds are commonly sourced from various plants, where they are present in fruits, vegetables, and certain herbs. Flavonoids such as 3,7,4'-Trihydroxyflavone are known for their role in plant pigmentation and protection against environmental stressors.</p>

<p>Kaempferol 3-b-glucopyranoside is a flavonoid glycoside, which is a compound typically isolated from a variety of plants, including tea, broccoli, and fruits such as apples and grapes. It represents a crucial category of secondary metabolites prevalent in the plant kingdom, often serving roles in plant defense and pigmentation. The mode of action of Kaempferol 3-b-glucopyranoside is primarily attributed to its antioxidant properties, effectively scavenging free radicals and thereby mitigating oxidative stress. Furthermore, it is known to modulate various cellular signaling pathways, including those related to apoptosis and inflammation, by influencing kinase activity and gene expression.</p>

Herbacetin-8-glucoside-3-sophoroside is a flavonoid glycoside derivative, which is a bioactive compound commonly found in plant sources, particularly within the flavonoid subclass. This compound is notable for its multifunctional biological activities and potential health benefits. It is primarily sourced from plant materials, where it can be extracted and isolated for further study and application.

Capillary protectant; free radical scavenger; antioxidant

<p>7-Benzyloxy-2',4',5'-trimethoxyisoflavone is a specialized type of isoflavone, which is a class of naturally occurring organic compounds related to flavonoids. It is typically derived from plant sources, showcasing the vast chemical diversity and potential bioactivity present in botanicals. This compound operates through various biochemical pathways, often interacting with specific cellular receptors or enzymes to exert its effects. Its mode of action can include antioxidant activity or modulation of signaling pathways, which are crucial for maintaining cellular homeostasis and function. The applications of 7-Benzyloxy-2',4',5'-trimethoxyisoflavone are primarily in the realm of pharmacological research, where it is explored for its potential therapeutic uses. It may be investigated for its roles in combating oxidative stress or influencing pathways associated with inflammation and cellular growth. científicos pursue its study to uncover new medical insights and develop novel therapeutic strategies.</p>

<p>Luteolin 3'-O-β-D-glucuronide is a flavonoid glucuronide, which is primarily derived from various plant sources, including fruits, vegetables, and certain herbs. As a metabolite of luteolin, it is formed through the addition of a glucuronic acid moiety, enhancing its solubility and bioavailability in biological systems.</p>

<p>Lupinisoflavone A is a naturally occurring bioactive compound, specifically an isoflavone, which is extracted from the seeds and other parts of lupine plants. The lupine species are known for their rich phytochemical profile, which includes various bioactive compounds with potential health benefits. Lupinisoflavone A is structurally characterized by its isoflavone backbone, contributing to its diverse biological effects.</p>

<p>8-Hydroxygenistein is a naturally occurring isoflavone, which is a type of polyphenolic compound. It is derived primarily from plants, particularly soybeans and other legumes. This compound exhibits its mode of action through selective inhibition of tyrosine kinase enzymes, interference with the cell cycle, and modulation of signal transduction pathways. It also acts as a potent antioxidant, scavenging free radicals and reducing oxidative stress within cells.</p>

<p>Induces cell death in human prostate cancer by disrupting mitochondria function</p>

Isorhamnetin-5-O-methyl ether-3-glucoside is a flavonoid glycoside, which is a secondary metabolite typically found in various plant sources such as fruits, vegetables, and certain herbs. It is part of a larger class of compounds known as flavonoids, which are well-known for their diverse biological activities. The mode of action of Isorhamnetin-5-O-methyl ether-3-glucoside primarily involves its antioxidant properties, which allow it to neutralize free radicals and reduce oxidative stress.

Linarin is a naturally occurring flavonoid compound, which is primarily extracted from plant sources such as the leaves of *Buddleja davidii* and *Mentha aquatica*. This flavonoid is notable for its biological activity, which is characterized by its interaction with various enzymes and receptors involved in cellular processes.

<p>4',5,7-Trimethoxyflavone is a polymethoxyflavone, which is a type of naturally occurring flavonoid compound. It is primarily sourced from various plants, notably within the Rutaceae family. These compounds are characterized by the presence of multiple methoxy groups attached to the flavone core structure.</p>

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Zapotin is a natural compound, which is sourced from the seeds of the Sapote Blanco (Casimiroa edulis). This organic compound exhibits its mode of action primarily through its interaction with cancerous cells. Zapotin induces apoptosis in these cells by modulating key signaling pathways, thereby preventing cell proliferation and enhancing programmed cell death. This mechanism underscores its potential as a chemopreventive agent.

<p>5-Hydroxy-3',3,4',5',7-pentamethoxyflavone is a naturally occurring flavone, which is a type of flavonoid found primarily in plants. These compounds often serve as plant secondary metabolites, with potential roles in various physiological and ecological functions. This particular flavone is primarily derived from certain species within the plant kingdom, where it acts as part of the plant’s defense mechanism against pathogens and herbivores.</p>

<p>Mitochondrial ATPase and phosphodiesterase inhibitor</p>

7,4'-Dimethoxyflavone is a naturally occurring flavonoid derivative, which is found predominantly in certain plants, particularly within the citrus family. This compound is characterized by the presence of two methoxy groups attached to its flavone backbone. It functions by interacting with various biological pathways, including those involved in antioxidant and anti-inflammatory responses. Its molecular structure allows it to modulate enzyme activities and receptor interactions, although the exact mechanisms are still under study.

<p>(±)-Eriodictyol is a flavonoid compound, which is a type of bioactive polyphenol. It is derived primarily from certain plant sources, notably within the Ericaceae and Solanaceae families. The compound exhibits its mode of action through its potent antioxidant and anti-inflammatory activities, mechanisms that involve the scavenging of free radicals and the inhibition of pro-inflammatory pathways.</p>

<p>Dihydromyricetin is a flavonoid compound, which is derived from the tree Hovenia dulcis. This plant, commonly known as the Japanese raisin tree, serves as the primary natural source for this bioactive substance. The mode of action of dihydromyricetin involves modulation of neurotransmitter receptors, particularly GABA_A receptors, wherein it contributes to alleviating alcohol-induced neuroinhibition. Additionally, it enhances the liver's ability to metabolize alcohol and reduces oxidative stress by acting as an antioxidant.</p>

Piscerythrone is a specialized chemical compound derived from certain marine organisms, which is primarily sourced from vibrant crustaceans. It acts through biochemical interactions that modulate pigmentation processes at the cellular level. The compound's mode of action involves binding to specific receptors involved in the enzymatic pathways of pigment production, influencing the synthesis and deposition of pigments such as astaxanthin.

Demethoxysudachitin is a flavonoid compound, which is naturally sourced from the peel of the sudachi fruit, a type of small citrus fruit native to Japan. This compound exhibits a mode of action primarily through its potent antioxidant activity, which involves scavenging free radicals and reducing oxidative stress within biological systems. It also plays a role in modulating various enzymatic pathways, contributing to its pharmacological properties.

<p>7,8-Dimethoxyflavone is a synthetic flavonoid compound, which is derived from natural flavones found in various plant species. As a structurally modified version of naturally occurring flavonoids, it exhibits a range of biological activities. The mode of action of 7,8-Dimethoxyflavone involves interaction with various cellular pathways, including modulation of kinase and receptor activity, potentially impacting signal transduction processes.</p>

<p>Pinostrobin is a natural flavonoid compound, which is derived primarily from the rhizomes of plants such as the fingerroot (Boesenbergia rotunda) and various species of the Pinus genus. Its mode of action involves potent antioxidant activity, where it scavenges free radicals, thus reducing oxidative stress. Additionally, Pinostrobin exhibits antimicrobial properties by disrupting microbial cell membranes and inhibiting essential microbial enzymes.</p>

<p>5,6-Dihydroxy-7-methoxyflavone is a naturally occurring flavonoid compound, which is predominantly sourced from various plants, often found in the leaves, stems, or roots. This compound belongs to the broader class of flavonoids, which are known for their diverse biochemical activities. As a flavone derivative, its structure includes hydroxyl and methoxy functional groups that contribute to its biological activity.</p>

Tilianin is a flavonoid glycoside, which is a natural compound derived from the plant **Dracocephalum moldavica**. It is primarily sourced from the leaves and flowers of this herbaceous plant, belonging to the Lamiaceae family. Tilianin exerts its effects through several biochemical pathways, most notably by inhibiting inflammatory mediators and modulating oxidative stress pathways. This mode of action suggests its potential as an anti-inflammatory and antioxidant agent.

Myricetin is a naturally occurring flavonoid, which is primarily sourced from various fruits, vegetables, teas, and medicinal plants. It is found abundantly in the bark of the Myrica species, as well as in grapes, onions, and berries. Myricetin functions as an antioxidant by scavenging free radicals, thus mitigating oxidative stress. It also exerts anti-inflammatory effects through modulation of signaling pathways, including the inhibition of nuclear factor-κB (NF-κB) and downregulation of pro-inflammatory cytokines.

2',4'-Dimethoxy-6-methylflavanol is a specialized flavonoid compound, which is a type of secondary metabolite primarily found in various plants. These compounds are often extracted from plants recognized for their rich phytochemical profiles, such as those in the Fabaceae or Rutaceae families. Flavonoids, including 2',4'-Dimethoxy-6-methylflavanol, are known for their diverse biological activities, including antioxidant, anti-inflammatory, and potential anti-cancer properties.

<p>Genistein-5,4'-dimethyl ether is a methylated isoflavone, which is a naturally occurring compound primarily extracted from various plant sources, particularly legumes. This bioactive compound is a derivative of the well-known isoflavone genistein, with methyl groups added at specific positions on the aromatic ring structure, altering its chemical properties and biological activity.</p>

<p>5,7-Dimethoxy-4'-hydroxyflavanone is a synthetic flavonoid compound, which is derived from the structural modification of naturally occurring flavonoids found in plants. Alterations in its chemical structure provide enhanced properties for various scientific applications. The mode of action of this compound primarily involves its ability to act as a potent antioxidant. By scavenging free radicals, it protects biological systems from oxidative stress, thereby playing a pivotal role in cellular protection and homeostasis.</p>

3-Hydroxy-6,2',4',5'-tetramethoxyflavone is a naturally occurring flavone, which is a type of polyphenolic compound predominantly found in certain plants. This compound belongs to the broader class of flavonoids, often isolated from plant sources like tropical herbs and medicinal plants renowned for their rich bioactive profiles.

6-Methoxyflavanone is a naturally occurring flavonoid compound, which is typically derived from plant sources, particularly those high in flavonoids such as certain fruits and herbs. The compound is characterized by the presence of a methoxy group, which distinguishes it from other flavanones and may influence its bioactivity and solubility properties. Its mode of action often involves interactions with biological pathways that regulate inflammation, oxidative stress, and cellular metabolism, potentially through mechanisms such as enzyme inhibition or modulation of receptor activity.

7-O-Prenyloxyflavanone is a bioactive compound, specifically a flavanone, which is isolated from various plant sources known for their rich flavonoid content. The compound is characterized by the attachment of a prenyl group at the 7-O position of the flavanone structure, which imparts unique biological activities.

4',7-Dihydroxyflavone is a flavonoid compound, which is naturally found in various plants. This compound is sourced predominantly from the plant kingdom, particularly in leaves and flowers, where it plays a crucial role in plant defense mechanisms. The mode of action of 4',7-dihydroxyflavone involves modulation of various signaling pathways, most notably its interaction with the tropomyosin receptor kinase B (TrkB), which is known for its involvement in neuronal survival and synaptic plasticity.

<p>Syringetin is a flavonoid compound, which is derived from natural sources such as grapes and other plants. This compound belongs to the class of polyphenolic compounds known as flavonols, which are secondary metabolites found abundantly in nature. Syringetin exhibits its mode of action primarily through its strong antioxidant properties, which allow it to neutralize free radicals and reduce oxidative stress in biological systems. This activity can contribute to the protection of cells and biomolecules from oxidative damage, a process implicated in aging and various diseases.</p>

6-Methylflavone is a synthetic flavonoid, which is derived from the structural modification of natural flavonoids commonly found in various plants. This compound has garnered interest due to its pharmacological potential, particularly as a modulator of the central nervous system. The mode of action of 6-Methylflavone involves its interaction with the GABA_A receptors, where it is believed to function as a positive allosteric modulator. This interaction enhances the inhibitory effects of GABA, a primary neurotransmitter in the brain, thereby potentially exerting anxiolytic (anxiety-reducing) effects.