Cannabinoidi
I cannabinoidi sono una classe di composti chimici diversi derivati dagli acidi grassi o dai polichetoidi, che agiscono sui recettori dei cannabinoidi nelle cellule, alterando il rilascio di neurotrasmettitori nel cervello. Presenti principalmente nelle piante di cannabis, cannabinoidi come il THC e il CBD sono ampiamente studiati per i loro effetti terapeutici, tra cui il sollievo dal dolore, le proprietà anti-infiammatorie e il loro potenziale utilizzo nelle malattie neurodegenerative. Da CymitQuimica troverai una vasta gamma di cannabinoidi per la ricerca in farmacologia, neurobiologia e chimica medica.
Trovati 318 prodotti di "Cannabinoidi"
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GAT229
CAS:GAT229 is a CB1 positive modulator, enhancing CB agonist activity without direct activation; influences binding, signaling, and lowers ocular pressure in mice.Formula:C22H18N2O2Colore e forma:SolidPeso molecolare:342.39CB1-IN-2
CAS:CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.Formula:C17H19Cl2N5OColore e forma:SolidPeso molecolare:380.27LEI-101
CAS:LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.Formula:C23H25FN4O4SPurezza:98%Colore e forma:SolidPeso molecolare:472.53SMM-189
CAS:SMM-189 is a potent and selective CB2 inverse agonist.Formula:C19H12Cl2O3Colore e forma:SolidPeso molecolare:359.2CAY10412
CAS:Anandamide (AEA) is an endocannabinoid with neural reuptake. CAY10412, an AEA analog, inhibits this reuptake without binding to CB receptors.Formula:C25H36O2SColore e forma:SolidPeso molecolare:400.62VSN-16
CAS:VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.Formula:C18H26N2O3Colore e forma:SolidPeso molecolare:318.41UCM710
CAS:UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).Formula:C19H34O3Purezza:98%Colore e forma:SolidPeso molecolare:310.47CB1R Allosteric modulator 4
CAS:Modulates CB1R positively; inhibits cAMP production; strong β-arrestin-2 recruitment.Formula:C20H17N3O2SColore e forma:SolidPeso molecolare:363.43S-777469
CAS:S-777469: Selective CB2 agonist, oral, inhibits itching in mice (Ki: 36 nM). Anti-pruritic.Formula:C23H27FN2O4Colore e forma:SolidPeso molecolare:414.47CB1R Allosteric modulator 1
CAS:CB1R modulator 1 (compound 11), a potent CB1R inhibitor, decreases activity of orthosteric ligands.Formula:C24H24ClN3OColore e forma:SolidPeso molecolare:405.92CB1/2 agonist 4
CAS:<p>CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.</p>Formula:C27H45NO3Colore e forma:SolidPeso molecolare:431.65Arvanil
CAS:Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.Formula:C28H41NO3Purezza:99.49%Colore e forma:SolidPeso molecolare:439.63(R)-SLV 319
CAS:(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.Formula:C23H20Cl2N4O2SColore e forma:SolidPeso molecolare:487.4LH 21
CAS:LH-21, a strong CB1 receptor antagonist, curbs eating and lessens weight gain in obese rats.Formula:C20H20Cl3N3Colore e forma:SolidPeso molecolare:408.75NIDA 41020
CAS:NIDA 41020 is a CB1 receptor antagonist.Formula:C23H24Cl2N4O2Purezza:98%Colore e forma:SolidPeso molecolare:459.37AM-6538
CAS:AM6538: long-acting, high-affinity CB antagonist similar to rimonabant, useful for studying cannabinoid agonists.Formula:C26H25Cl2N5O4Colore e forma:SolidPeso molecolare:542.412-Arachidonoylglycerol
CAS:In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligandFormula:C23H38O4Purezza:95%Colore e forma:LiquidPeso molecolare:378.55AM6545
CAS:AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.Formula:C26H23Cl2N5O3SPurezza:97.03%Colore e forma:SolidPeso molecolare:556.46CB2 receptor agonist 3
CAS:GP 2A is a selective agonist of CB2 receptor.Formula:C24H23Cl2N3OColore e forma:SolidPeso molecolare:440.36O-2093
CAS:anandamide uptake inhibitorFormula:C34H43Cl2NO3Purezza:98%Colore e forma:SolidPeso molecolare:584.62CID1172084
CAS:CID1172084, a novel high-potent GPR55 agonist, interacts with cannabinoid receptors.Formula:C23H18FN5O2S2Colore e forma:SolidPeso molecolare:479.55COR167
CAS:<p>COR167 is a CB2 agonist with immunomodulatory effects, protective brain properties, and antinociception.</p>Formula:C28H38N2O2Colore e forma:SolidPeso molecolare:434.61PGN36
CAS:PGN36 (Compound 18) is a potent CB2 receptor antagonist with a high affinity (Ki=0.09 μM).Formula:C21H23N3O3Colore e forma:SolidPeso molecolare:365.43CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Formula:C18H19F3N4O2Purezza:99.6%Colore e forma:SolidPeso molecolare:380.36KLS-13019
CAS:KLS-13019 is a highly effective and orally active GPR55 receptor antagonist, neuroprotective can reverse chemotherapy-induced peripheral neuropathy (CIPN).Formula:C22H29NO3Purezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:355.47GAT228
CAS:GAT228, an allosteric ligand for the cannabinoid receptor 1 (CB1), functions as the enantiomer of GAT211 [1].Formula:C22H18N2O2Colore e forma:SolidPeso molecolare:342.39(S)-SLV 319
CAS:Ibipinabant (SLV319), a potent CB1 antagonist, K i = 7.8 nM, >1000x selective over CB2, for obesity and diabetic research.Formula:C23H20Cl2N4O2SColore e forma:SolidPeso molecolare:487.4CB1/2 agonist 2
CAS:CB1/2 agonist 2 binds tightly to cannabinoid receptors, acting fully on CB1 and inversely on CB2.Formula:C26H43NO3Colore e forma:SolidPeso molecolare:417.62CB1 inverse agonist 2
CAS:CB1 inverse agonist 2, an oral drug, counters CB1 effects, reducing CP55940-induced hypothermia and anorexia in mice.Formula:C24H20ClFN2OSColore e forma:SolidPeso molecolare:438.94COR 170
CAS:<p>inverse agonist of CB2 receptors</p>Formula:C31H36N2O2Purezza:98%Colore e forma:SolidPeso molecolare:468.63CB1R Allosteric modulator 2
CAS:<p>Compound 18 is a potent CB1R allosteric modulator that acts as a negative modulator (NAM) for CB1R orthosteric ligands.</p>Formula:C19H15ClFN3OColore e forma:SolidPeso molecolare:355.79ANEB-001
CAS:ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.Formula:C22H24ClF3N2O2Colore e forma:SolidPeso molecolare:440.89AZD1940
CAS:AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.Formula:C20H29F2N3O2SPurezza:98.68%Colore e forma:SolidPeso molecolare:413.52PSB-CB5
CAS:PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study obesity and metabolic disorders.Formula:C20H17ClN2O2SPurezza:99.26%Colore e forma:SolidPeso molecolare:384.88CB1R antagonist 1
CAS:CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.Formula:C18H23F3N2O3SPurezza:99.65%Colore e forma:SolidPeso molecolare:404.45Taranabant
CAS:<p>Inverse agonist of cannabinoid receptor CB1R. Taranabant was studied for its effect on smoking cessation and inducing weight loss. Serious adverse effects associated with this compound prevented further development as a drug in the clinic.</p>Formula:C27H25ClF3N3O2Purezza:Min. 95%Colore e forma:SolidPeso molecolare:515.95 g/molSCH-336
CAS:<p>SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.</p>Formula:C23H25NO8S3Purezza:95.01%Colore e forma:SolidPeso molecolare:539.64CB1 agonist 1
CAS:CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.Formula:C24H24N2O5SPurezza:98.56%Colore e forma:SolidPeso molecolare:452.52JTE-907
CAS:JTE-907 是一种具有高度选择性和口服活性的 CB2 受体反向激动剂。JTE-907在体内展现出抗炎活性。Formula:C24H26N2O6Purezza:99.93%Colore e forma:SolidPeso molecolare:438.47Nonabine
CAS:Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.Formula:C25H33NO2Purezza:99.82% - 99.94%Colore e forma:SolidPeso molecolare:379.54Olorinab
CAS:<p>Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.</p>Formula:C18H23N5O3Purezza:97.67% - 98.47%Colore e forma:SolidPeso molecolare:357.41SR144528
CAS:<p>SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).</p>Formula:C29H34ClN3OPurezza:99.63%Colore e forma:SolidPeso molecolare:476.05AM-1235
CAS:AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.Formula:C24H21FN2O3Purezza:99.92%Colore e forma:SolidPeso molecolare:404.43CB2R PAM
CAS:CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.Formula:C21H24BrFN2O2Purezza:99.09%Colore e forma:SolidPeso molecolare:435.3311(Z),14(Z)-Eicosadienoic Acid Ethanolamide
CAS:11(Z),14(Z)-Eicosadienoic acid ethanolamide is an ethanolamide derivative of 11(Z),14(Z)-eicosadienoic acid.Formula:C22H41NO2Colore e forma:SolidPeso molecolare:351.57Prostaglandin E2-1-glyceryl ester
CAS:Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].Formula:C23H38O7Colore e forma:SolidPeso molecolare:426.55O-Arachidonoyl glycidol
CAS:O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].Formula:C23H36O3Colore e forma:SolidPeso molecolare:360.53COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formula:C16H16ClNO3SPurezza:99.75%Colore e forma:SolidPeso molecolare:337.82GSK-554418A
CAS:GSK-554418A, a novel azaindole CB(2) agonists, is used for the treatment of chronic pain. It is efficacious in the acute model and the chronic joint pain model.Formula:C19H19ClN4O2Colore e forma:SolidPeso molecolare:370.83PSB-SB1202
CAS:PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].Formula:C23H26O4Colore e forma:SolidPeso molecolare:366.45
