Zuccheri e nucleobasi della spina dorsale
Gli zuccheri dello scheletro e le basi azotate sono componenti essenziali degli acidi nucleici come DNA e RNA. Lo scheletro è composto da gruppi zuccheri e fosfati, mentre le basi azotate formano il codice genetico attraverso l'appaiamento delle basi. Questi composti sono fondamentali nello studio della genetica e della biologia molecolare. Presso CymitQuimica, è possibile trovare una varietà di zuccheri dello scheletro e basi azotate per la ricerca e l'uso in laboratorio.
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6-Aminouracil
CAS:6-Aminouracil is a hydroxylated form of uracil. It has inhibitory properties against protein synthesis in bacteria, acting as an inhibitor of the enzyme dihydroorotase. 6-Aminouracil has been shown to be effective against PC3 cells and has high resistance to hydrolysis by acid or alkali. The reaction mechanism for the conversion of uracil to 6-aminouracil is unclear; however, it may involve a nucleophilic attack on the hydroxyl group.
Formula:C4H5N3O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:127.1 g/mol1,3,9-Trimethylxanthine
CAS:Prodotto controllato1,3,9-Trimethylxanthine is a naturally occurring purine alkaloid that has been shown to have cytosolic calcium ion-antagonistic properties. It can also act as an antioxidant by donating electrons to free radicals and inhibiting lipid peroxidation. This compound is found in coffee beans and other sources of caffeine. It binds to the receptor for adenosine, which causes the antagonistic effects on intracellular calcium concentration. Trimethylxanthine can also be used to treat ventricular arrhythmias and increase locomotor activity in mammals. Trimethylxanthine has been shown to be effective in wastewater treatment as it removes organic pollutants from water by oxidizing them with hydrogen peroxide or chlorine gas.
Formula:C8H10N4O2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:194.19 g/mol5-Benzyl-1-(2-hydroxyethoxymethyl)uracil
CAS:5-Benzyl-1-(2-hydroxyethoxymethyl)uracil is a cytostatic drug that has been shown to inhibit the growth of cancer cells by inhibiting the enzyme activities necessary for DNA replication and transcription. This compound has been found to be effective in treating metastatic colorectal cancer in experimental models, as well as skin cancers in mice. 5-Benzyl-1-(2-hydroxyethoxymethyl)uracil is also an inhibitor of HIV infection, which may be due to its ability to block the synthesis of uridine. The symptoms that are caused by this drug are not yet known.Formula:C14H16N2O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:276.29 g/mol3’,5’-Bis-O-benzoyl-2’-Deoxy-2’-fluoro-4-deoxy-arabinouridine
CAS:Please enquire for more information about 3’,5’-Bis-O-benzoyl-2’-Deoxy-2’-fluoro-4-deoxy-arabinouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurezza:Min. 95%5-Methoxyuracil
CAS:5-Methoxyuracil is a labile, colorless and crystalline compound that occurs spontaneously in the presence of oxygen. It has a chemical structure similar to thiourea, with one methyl group substituted for the amino group on the heterocycle. 5-Methoxyuracil is used as a precursor for synthesis of thymine and uracil. It also acts as an antioxidant, preventing reactive oxygen species from causing cellular damage. 5-Methoxyuracil can be used in regenerative medicine to increase the production of messenger RNA (mRNA) and ribosomal RNA (rRNA). This drug is used as a prebiotic agent and can be synthetically produced by dimethylation of uridine followed by ethyl formate oxidation.Formula:C5H6N2O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:142.11 g/mol6-Azathymine
CAS:6-Azathymine is a compound that belongs to the group of amides. It has shown bacterial strain specificity and can be used for the treatment of infections caused by Group P2 bacteria. 6-Azathymine inhibits the enzyme activity of toll-like receptor, which is responsible for immune response and inflammation. It also has been shown to inhibit photosynthetic activity in plants. This drug may also be useful for eye disorders, such as retinitis pigmentosa and macular degeneration. 6-Azathymine is activated by hydroxyl groups, which leads to its toxicity at high concentrations.
Formula:C4H5N3O2Colore e forma:PowderPeso molecolare:127.1 g/mol8-Methylxanthine
CAS:8-Methylxanthine is a metabolite of caffeine and theophylline. It has been shown to be a pro-inflammatory cytokine that stimulates the production of other pro-inflammatory cytokines such as interleukin (IL)-1β, IL-6, and tumor necrosis factor alpha (TNFα). 8-Methylxanthine is also a substrate for cytochrome P450 enzyme activity, which is responsible for metabolizing many drugs and other chemicals in the body. This compound has been detected in human liver and urine samples. 8-Methylxanthine has cytotoxic properties and may serve as an antioxidant. Mass spectrometric detection methods are used to identify this compound in biological fluids.Formula:C6H6N4O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:166.14 g/mol6-Chloro-3-methyluracil
CAS:Intermediate in the synthesis of alogliptin
Formula:C5H5ClN2O2Purezza:Min. 98 Area-%Colore e forma:Off-White PowderPeso molecolare:160.56 g/mol7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione
CAS:Prodotto controllato7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione is a drug that belongs to the group of adenosine receptor antagonists. It has been shown to inhibit phosphodiesterase activity and is used as a pharmaceutical dosage. 7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione has been shown to bind to the 5HT2C receptor in vitro. This drug may have therapeutic potential for obesity and type 2 diabetes mellitus treatment.Formula:C23H28FN5O3Purezza:Min. 95%Peso molecolare:441.5 g/mol2-Chloroinosine 3',4',6'-triacetate
CAS:2-Chloroinosine 3',4',6'-triacetate is a reagent, useful intermediate, fine chemical, and speciality chemical. It is used as an important building block in organic synthesis. 2-Chloroinosine 3',4',6'-triacetate can be used as a versatile building block for the synthesis of many other compounds. The high quality and usefulness of this compound make it a good choice for research chemicals.Formula:C16H17ClN4O8Purezza:Min. 95%Colore e forma:White to pale yellow solid.Peso molecolare:428.78 g/molN2-Pivaloylguanine
CAS:N2-Pivaloylguanine is a versatile building block that can be used in the synthesis of many complex compounds. It has been shown to be an excellent reagent for the synthesis of heterocyclic molecules, and is also used as a reactant in a number of chemical reactions. N2-Pivaloylguanine is a high quality, useful intermediate that can be used to make other compounds, such as pharmaceuticals and agrochemicals. It is also a useful scaffold for the synthesis of research chemicals.Formula:C10H13N5O2Purezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:235.24 g/mol2',3'-Di-O-isopropylidene-5-hydroxymethyl uridine
CAS:2',3'-Di-O-isopropylidene-5-hydroxymethyl uridine (DIOI) is a fine chemical that can be used as a versatile building block or an intermediate in the research of complex compounds. DIOI is also a useful reagent, which may be used as a starting material for the synthesis of other compounds. It has been shown to have high quality and is available at CAS No. 3816-77-1.Formula:C13H18N2O7Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:314.29 g/mol5,6-Dihydrouracil
CAS:5,6-Dihydrouracil is a model system and a drug that belongs to the class of inhibitors. It inhibits DNA polymerase, RNA polymerase, and other enzymes by binding to their active sites. 5,6-Dihydrouracil has been shown to inhibit hydrogen bonding interactions with the DNA template or matrix effect in vitro. This drug has also been shown to have an effect on energy metabolism in humans. 5,6-Dihydrouracil is used as a probe for enzyme activity and receptor binding studies in vitro. Additionally, it can be used as an analytical method for determining the presence of dihydrouracil in human serum.Formula:C4H6N2O2Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:114.1 g/mol5-Azauracil
CAS:5-Azauracil is a glycosylase that specifically hydrolyzes the N-glycosidic bond in uridine. It is a potential anticancer agent that inhibits the growth of cancer cells by targeting intracellular targets and inhibiting enzyme activities. 5-Azauracil binds to nitrogen atoms in the enzyme active site, causing an alteration in the hydrogen bonding network and resulting in inhibition of enzyme activity. The reaction mechanism involves the formation of orotic acid as a product. 5-Azauracil also has been shown to inhibit x-ray diffraction data, which may be due to its ability to bind to an enzyme's metal cofactors such as iron or copper.Formula:C3H3N3O2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:113.07 g/mol5,6-Dihydro-ara-uridine
CAS:5,6-Dihydro-ara-uridine is a fine chemical that belongs to the group of compounds known as uridine analogues. It can be used as a versatile building block in the synthesis of other compounds and has been shown to be an effective intermediate in the synthesis of various research chemicals. 5,6-Dihydro-ara-uridine is also commonly used as a reaction component and reagent in the polymerization process. This compound is high quality and has CAS No. 30100-83-5.
Formula:C9H14N2O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:246.22 g/molN2-Phenoxyacetyl guanine
CAS:N2-Phenoxyacetyl guanine is a labile nucleoside that can be synthesized by the aminoacylation of guanosine with phenoxyacetic acid. It has been shown to have an important role in oxidative DNA damage, which may lead to mutagenesis and cancer. N2-Phenoxyacetyl guanine is stereoselective and binds preferentially to the GGC sequence, and it is also aminopropylated at its 2′ position. This nucleoside is not ionizing but can be degraded by radiation or enzymes such as deaminases.Formula:C13H11N5O3Purezza:Min. 95%Peso molecolare:285.26 g/molUracil-4-acetic acid
CAS:Uracil-4-acetic acid is a monocarboxylic acid that is synthesized in mammalian cells. It can also be obtained by hydrolysis of orotic acid, which was previously synthesized from uridine and phosphorolysis of sephadex g-100. Uracil-4-acetic acid is used to produce uridine through the action of an enzyme called uridine phosphorylase. This enzyme catalyzes the reaction between ATP and uracil, as well as the conversion of orotic acid to orotidine 5′-monophosphate decarboxylase. Uracil-4-acetic acid has been shown to inhibit the growth of toxoplasma, but it has not been determined whether this inhibition is due to its role in the synthesis of uridine or its toxic effects on the parasite.Formula:C6H6N2O4Purezza:Min. 95%Colore e forma:White SolidPeso molecolare:170.12 g/mol6-Methylmercaptopurine
CAS:6-Methylmercaptopurine is an important metabolite of 6-methylmercaptopurine, which is a vital component of the nucleotide synthesis pathway. It is used in analytical methods to determine levels of nucleotides, as well as in biological studies for its effect on autoimmune diseases. 6-Methylmercaptopurine can inhibit replication by inhibiting the methyltransferase enzyme.Formula:C6H6N4SPurezza:Min. 95%Colore e forma:Off-White Yellow PowderPeso molecolare:166.2 g/mol5-Bromouracil
CAS:5-Bromouracil is a cytotoxic agent that inhibits the synthesis of DNA by inhibiting the enzyme thymine-5-bromo-2'-deoxyribonucleotide synthetase. It also has genotoxic effects on the organism, which can be observed in transfection experiments with human lymphocytes and polymerase chain reaction (PCR) experiments. 5-Bromouracil binds to the hydroxyl group of thymine and interacts with the nucleic acid bases, blocking the process of DNA synthesis. This drug is used to treat cancer in humans, but it is also toxic to eosinophils, which are white blood cells that produce chemicals such as peroxidases that help fight infections. The mechanism of action for 5-Bromouracil is not yet fully understood.Formula:C4H3BrN2O2Purezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:190.98 g/molN2-Acetylguanine
CAS:N2-Acetylguanine is a reactive compound that inhibits the growth of cancer cells in leukemia. It is an antimicrobial agent that has significant cytotoxicity against leukemia cells and other bacterial cells. N2-Acetylguanine reacts with dihydrozeatin to form acyclic nucleoside phosphonate, which inhibits the synthesis of DNA, RNA, and protein. This reaction yields a high yield of this product in a short period of time. The modification process also creates a more efficient method for synthesizing this compound. N2-Acetylguanine can be used to treat dyslipidemia by decreasing cholesterol levels in the blood and can also be used as an active substance in the treatment of diabetes mellitus type II and insulin resistance.Formula:C7H7N5O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:193.17 g/mol
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