Nucleotidi
I nucleotidi sono composti organici che fungono da mattoni per la costruzione degli acidi nucleici, essenziali per la formazione del DNA e dell'RNA. Ogni nucleotide è composto da una base azotata, una molecola di zucchero e uno o più gruppi fosfato. Questi nucleotidi si uniscono per formare lunghe catene, creando il materiale genetico che porta e trasmette informazioni genetiche in tutti gli organismi viventi. In questa sezione, troverai una vasta gamma di nucleotidi cruciali per la ricerca in genetica, biologia molecolare e biochimica. Sono fondamentali per studiare i processi genetici, sintetizzare acidi nucleici e sviluppare strumenti diagnostici e terapeutici. Da CymitQuimica, offriamo nucleotidi di alta qualità per supportare la tua ricerca scientifica e applicazioni, garantendo precisione e affidabilità nei tuoi esperimenti.
Sottocategorie di "Nucleotidi"
Trovati 2634 prodotti di "Nucleotidi"
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2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine
CAS:<p>2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine is a modified ribonucleoside that has antiviral and anticancer activity. It is synthesized by modifying the 5' hydroxyl group of the natural nucleoside, 2'-deoxyadenosine, with a 6-aminohexanoic acid to give 2'-deoxy-5'-O-(2,4,6-trimethoxybenzoyl)adenosine. This modification increases the affinity for viral DNA polymerases, leading to higher antiviral activity. The drug also has antitumor effects against human leukemia cells in culture.</p>Formula:C35H37N5O6Purezza:Min. 95%Colore e forma:Off-White To Light (Or Pale) Yellow SolidPeso molecolare:623.72 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
CAS:5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.Formula:C34H38N2O9Purezza:Min. 95%Colore e forma:Off-White PowderPeso molecolare:618.67 g/mol9-(2',3',5'-Tri-O-benzyl-β-D-arabinofuranosyl)adenine
CAS:9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is a nucleoside that has shown anticancer and antiviral properties. It inhibits replication of DNA and RNA in cells, which may be due to its ability to inhibit the synthesis of deoxyribonucleotides and ribonucleotides. This compound is synthetically produced from 2',3',5'-tri-O-benzyl b-D-arabinofuranosyl chloride and adenine monophosphate (AMP). 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is also known as arabinoside A.Formula:C31H31N5O4Purezza:Min. 95%Peso molecolare:537.61 g/mol5'-Deoxythymidine
CAS:<p>5'-Deoxythymidine is a nucleoside analog with low-energy electrons. This drug inhibits the synthesis of DNA by binding to the ribonucleotide reductase enzyme and preventing the conversion of ribonucleotides to deoxyribonucleotides. 5'-Deoxythymidine has been shown to inhibit cell growth in tumor cell lines, which may be due to its ability to interfere with mirna-mediated gene expression. This drug also has a kinetic effect on regulatory proteins, such as cyclin-dependent kinases, that are involved in the regulation of cell cycle progression.</p>Formula:C10H14N2O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:226.23 g/molβ-Nicotinamide adenine dinucleotide
CAS:Nicotinamide adenine dinucleotide (NAD), is a very important and essential coenzyme formed by the union of two nucleotides covalently bond to each other by their phosphates group. NAD is present in cells either in its oxidative form or in its reduced form, NAD+ and NADH respectively. They take part in many redox reactions, carrying electrons from one molecule to another.Formula:C21H27N7O14P2Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:663.43 g/molUridine 5'-triphosphate dihydrate trisodium salt
CAS:Uridine 5'-triphosphate dihydrate trisodium salt is a nucleotide that is involved in the synthesis of RNA. This product has been used as a supplement to promote healthy eyes and skin, as well as to treat Alzheimer's disease. It has been shown to be an efficient method for the detection of active substances by hydrophilic interaction chromatography (HILIC). The HILIC method involves separating molecules based on their hydrophobic or hydrophilic properties, which are determined by the ionic strength of the solution. Uridine 5'-triphosphate dihydrate trisodium salt binds with chloride ions, which prevents it from binding with other organic compounds. The chloride ions then serve as an end point that can be detected using ultraviolet light.Formula:C9H12N2O15P3·3Na·2H2OPurezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:586.12 g/molN6,3'-O-Dibenzoyl-2'-deoxyadenosine
CAS:<p>N6,3'-O-Dibenzoyl-2'-deoxyadenosine is a nucleoside that is used as a biochemical reagent in molecular biology. N6,3'-O-Dibenzoyl-2'-deoxyadenosine has been shown to be an inhibitor of the enzyme phosphodiesterase and also binds to DNA. This compound has been shown to have antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus and Clostridium perfringens. The lipophilicity of this compound allows it to cross the cell membrane and cleave DNA at the site of replication. N6,3'-O-Dibenzoyl-2'-deoxyadenosine is an analog of 6,4’-dihydroxybenzophenone (DBP) and can be synthesized from DBP by reacting with dibenzoyl chloride in chloroform</p>Formula:C24H21N5O5Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:459.47 g/molN4-Benzoyl-2'-deoxycytidine
CAS:N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.Formula:C16H17N3O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:331.33 g/mol2-Aminoperimidine hydrochloride
CAS:2-Aminoperimidine hydrochloride is the hydrochloride salt of 2-aminoperimidine, a polycyclic aromatic heterocycle featuring a fused naphthalene–pyrimidine ring system with an amino group at the 2-position. The protonated amino group forms a stable crystalline salt with hydrochloric acid, enhancing aqueous solubility and facilitating handling in laboratory applications.Formula:C11H9N3•(HCl)xPurezza:Min. 95%Colore e forma:PowderPeso molecolare:219.67 g/mol1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine
CAS:1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.Formula:C24H24N4O6Purezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:464.48 g/molN4-Benzoyl-2'-deoxy-2'-fluorocytidine
CAS:N4-Benzoyl-2'-deoxy-2'-fluorocytidine is a novel, synthetic nucleoside that has been shown to inhibit the growth of cancer cells and is being investigated as a potential anticancer drug. N4-Benzoyl-2'-deoxy-2'-fluorocytidine has also been found to be active against HIV, Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), and influenza A virus. It prevents the replication of viruses by inhibiting DNA synthesis in the host cell.Formula:C16H16FN3O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:349.31 g/molCyclic adenosine 5'-diphosphate ribose ammonium salt
CAS:Cyclic Adenosine 5'-diphosphate ribose ammonium salt (CADPRAM) is a potent inhibitor of cyclic nucleotide phosphodiesterases (PDEs). CADPRAM reversibly inhibits PDEs and prevents the hydrolysis of cAMP. This inhibition can lead to an increase in cytosolic Ca2+. CADPRAM also inhibits polymerase chain reaction, which is why it cannot be used for the treatment of infectious diseases. CADPRAM has been shown to inhibit the activity of enzymes that are known to play a role in clinical pathology, such as adenylate cyclase and phosphodiesterase type 3.Formula:C15H21N5O13P2·NH3Purezza:Min. 95%Colore e forma:White solid.Peso molecolare:558.33 g/molBiotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution
CAS:Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution is a novel, synthetic and highly purified ribonucleoside phosphoramidite. It is used as an activator of nucleic acid synthesis in the preparation of DNA and RNA. Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution has been shown to be effective against various types of cancer cells, including leukemic cells and breast cancer cells. The drug also inhibits the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV-2).Formula:C22H35N6O16P3S·xLiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:764.53 g/molThymidine-5'-triphosphate trisodium
CAS:Thymidine-5'-triphosphate or dTTP, is a nucleotide used by the cell to synthesize DNA molecules. Thymidine-5'-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of thymidine-5'-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).Formula:C10H17N2O14P3•Na3Purezza:(%) Min. 90%Colore e forma:White PowderPeso molecolare:551.14 g/mol3'-O-Allylguanosine
<p>3'-O-Allylguanosine is a antiviral agent that belongs to the group of synthetic nucleosides. It is a monophosphate analog of guanosine and an activator of ribonucleotide reductase. 3'-O-Allylguanosine has been shown to be effective against cancer cells in vitro. It has also been shown to inhibit DNA synthesis and promote DNA degradation in human leukemia cells, suggesting its potential use for the treatment of leukemia.</p>Formula:C13H17N5O5Purezza:Min. 95%Peso molecolare:323.3 g/mol5-Bromo-2'-deoxyuridine
CAS:<p>5-Bromo-2'-deoxyuridine (5-BrDU) is a nitrate reductase inhibitor that prevents the reduction of nitrate to nitrite by inhibiting the enzyme nitrate reductase. It is a genotoxic agent that has been shown to cause DNA damage and cell death in vitro. 5-BrDU has been shown to induce preconditioning in vivo, reducing neuronal injury after ischemia. This drug also binds to NMDA receptors and may be useful as a model system for studying neurodegenerative diseases such as Alzheimer's disease. 5-BrDU has been shown to inhibit the polymerase chain reaction in wild-type strains of bacteria, but not in strains with a mutation in their DNA gyrase genes.</p>Formula:C9H11BrN2O5Purezza:Min. 99 Area-%Colore e forma:White Off-White PowderPeso molecolare:307.1 g/mol2'-Deoxyadenosine-5'-triphosphate disodium salt
CAS:2'-Deoxyadenosine-5'-triphosphate disodium salt is a nucleotide that is formed from adenosine triphosphate (ATP) and deoxyadenosine monophosphate (dAMP). It is an intermediate in the biosynthesis of fatty acids, which are important components of cell membranes. This nucleotide can be used to measure the light exposure of bacteria. 2'-Deoxyadenosine-5'-triphosphate disodium salt has been shown to have antibacterial activity against some Gram-positive bacteria, such as Staphylococcus aureus. The effective dose for these bacteria is 5 µg/mL with a linear model. The biological properties of this nucleotide are still not fully understood, but it is thought to play a role in blood pressure regulation through its effects on fatty acid synthesis.Formula:C10H14N5O12P3Na2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:535.15 g/molCoenzyme A sodium salt hydrate
CAS:Coenzyme A is a biochemical that is required for the synthesis of fat molecules. It also plays an important role in the activation of fatty acids, as well as in the production of collagen and growth factor-β1. Coenzyme A sodium salt hydrate (CAS) is a cofactor that participates in various metabolic processes, including process optimization and conjugation reactions. It has been shown to increase the transcription of insulin-sensitive genes, which may be due to its ability to inhibit the activity of nonsteroidal anti-inflammatory drugs. This product can be used in transfection experiments and fluorescence assays for cervical cancer or insulin sensitivity.Formula:C21H36N7O16P3SNaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:790.53 g/mol5-Aminouridine
CAS:<p>5-Aminouridine is an analog of uridine that is used in the synthesis of RNA. It inhibits the synthesis of RNA by viruses, and it may also inhibit the synthesis of RNA by cells, including muscle cells. 5-Aminouridine has been shown to inhibit protein synthesis in muscle cells incubated with orotic acid. The drug may also interact with other drugs metabolized by UDP-glucose pyrophosphorylase, such as carbamazepine and phenytoin. This interaction may lead to decreased serum levels of these drugs following treatment with 5-aminouridine.</p>Formula:C9H13N3O6Purezza:Min. 90 Area-%Colore e forma:PowderPeso molecolare:259.22 g/molN4-Benzoyl-5-methylcytidine
CAS:N4-Benzoyl-5-methylcytidine is a labile chemical that can be uniquely prepared using biochimie. It has been shown to have anticodon activity in assays and is synthesized chemically. The nucleoside is phosphoramidite, which is methylated and reproducible. N4-Benzoyl-5-methylcytidine has been shown to inhibit the growth of cells by blocking the synthesis of purines and pyrimidines. It may also have biophysical properties that are related to its ability to bind to DNA.Formula:C17H19N3O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:361.35 g/mol
