Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3570 prodotti di "Nucleosidi"
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a,b-Methyleneguanosine 5'-diphosphate sodium salt
CAS:a,b-Methyleneguanosine 5'-diphosphate sodium salt is a chemical species that binds to the influenza virus neuraminidase. The drug binding site on the influenza virus neuraminidase has been identified in high resolution by NMR and X-ray crystallography. This drug is able to inhibit the release of infectious particles and prevent infection by the influenza virus, which is an important biological weapon in bioterrorism. The compound is not active against other viruses such as HIV and herpes simplex virus type 1. In addition, this chemical species also inhibits the activity of geniculate nucleus neurons and may be effective for treatment of chronic pain caused by nerve injury.Formula:C11H17N5O10P2·xNaPurezza:Min. 95%Peso molecolare:441.23 g/mol4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite
4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite is a novel, modified nucleoside with antiviral activity. It is activated by the addition of a DMT group to its 5' end and has an anticancer effect. The monophosphate form of 4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite has been shown to inhibit viral DNA synthesis in vitro and to be cytotoxic against human cancer cell lines. 4-(2-Cyanoethylthio)-5'-O-DMT- thymidine 3'-CE phosphoramidite is a high quality, high purity product that can be used as a nucleoside or nucleotide in anticancer drugs.Formula:C43H52N5O7PSPurezza:Min. 95%Peso molecolare:813.96 g/molN6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel, modified, activator with antiviral and anticancer properties. It is the monophosphate of the acetylated 2'-deoxyadenosine 3'-cyanoethylphosphoramidite and has been shown to be effective in inhibiting DNA synthesis in cell cultures. This product is synthesized using high purity reagents and purification techniques.Formula:C42H50N7O7PPurezza:Min. 95%Colore e forma:SolidPeso molecolare:795.86 g/mol7-Deaza-2-mercaptohypoxanthine
CAS:7-Deaza-2-mercaptohypoxanthine is a nucleoside that has been found to have anticancer activity in vivo. It has also been shown to inhibit the replication of HIV and herpes simplex virus. 7-Deaza-2-mercaptohypoxanthine is an analog of hypoxanthine, which is a nucleoside that can be found in DNA and RNA. In addition, this compound can be used as a phosphoramidite or nucleotide analogue for the synthesis of DNA and RNA. This compound can also be used as an antiviral agent against herpes simplex virus type 1 (HSV1).Formula:C6H5N3OSPurezza:Min. 95%Peso molecolare:167.19 g/mol6-Methylthiopurine ribonucleotide
CAS:6-Methylthiopurine ribonucleotide is an inhibitor that belongs to the group of analogs of betamethasone. It has been shown to have anti-cancer properties and can induce apoptosis in cancer cells. This compound has also been studied for its potential use in treating urinary tract infections, as it has been shown to inhibit the growth of bacteria such as chlorhexidine-resistant strains. Additionally, 6-Methylthiopurine ribonucleotide has been found to be a potent inhibitor of human kinase and may have therapeutic potential for a variety of diseases. This compound has also been investigated as an inhibitor of tolvaptan, which is used to treat conditions such as hyponatremia. Overall, 6-Methylthiopurine ribonucleotide shows promising potential for the treatment of various diseases and conditions.Formula:C11H15N4O7PSPurezza:Min. 95%Peso molecolare:378.3 g/mol7-Methylinosine
CAS:7-Methylinosine is a versatile compound that has various applications in different fields. It is used as an intermediate in the synthesis of drugs such as azasetron, eletriptan, and fructan. Additionally, it has been shown to have detergent properties that make it useful in cleaning products. 7-Methylinosine also plays a role in cholesterol metabolism and has been implicated in the development of fibrosis. Studies have found that this compound can inhibit the activity of enzymes involved in glucosinolate biosynthesis and may play a role in plant defense against pathogens. Furthermore, 7-Methylinosine has been isolated from Nocardia sp., which suggests its potential use as a source of novel bioactive compounds.Formula:C11H16N4O5Purezza:Min. 95%Peso molecolare:284.27 g/molBiotin-11-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) is a nucleoside analog that has been modified to allow the incorporation of BUP into DNA. The modification of BUP with lithium salts allows for the covalent attachment of BUP to DNA. This incorporation of BUP into DNA prevents the polymerase from binding to DNA and thus inhibits replication. Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) has demonstrated anticancer and antiviral activity as well as being novel and high quality.Formula:C28H45N6O18P3S·xLiPurezza:Min. 95%Peso molecolare:878.67 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is an activator of DNA polymerase. It has been shown to be a potent inhibitor of viral replication and an anticancer agent in vitro. The compound has also been shown to inhibit the growth of tumor cells in vivo. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue that has not been previously reported.Purezza:Min. 95%2',3',5'-Tris-O-[tert-butyldimethylsilyl]-2-chloroadenosine
CAS:2',3',5'-Tris-O-[tert-butyldimethylsilyl]-2-chloroadenosine is a phosphoramidite that can be used in the synthesis of ribonucleosides, deoxyribonucleosides, and nucleoside analogues. It is a novel compound that has antiviral and anticancer properties. This product is synthesized from 2,3,5-trichloropyrimidine by reaction with tert-butyldimethylsilyl chloride in the presence of triethylamine. The product is purified by vacuum distillation and characterized using proton nuclear magnetic resonance (NMR) spectroscopy.Formula:C28H54ClN5O4Si3Purezza:Min. 95%Peso molecolare:644.47 g/mol5'-O-Benzoyl-2'-deoxyuridine
CAS:5'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is a component of DNA. 5'-O-Benzoyl-2'-deoxyuridine is used as an antiviral agent and for the treatment of some cancers, including lymphomas, leukemia, and certain types of solid tumors. It has also been shown to be effective in the treatment of hepatitis B virus infection. This compound inhibits viral replication by competing with natural nucleosides for incorporation into DNA and RNA. 5'-O-Benzoyl-2'-deoxyuridine binds to double helix DNA at the groove between adenine and thymine bases and prevents further binding of nucleotides to this site. It also inhibits viral DNA synthesis by preventing conversion of ribonucleotides to deoxynucleosides. This drug is not active against bacteria or fungi; however, it can cause serious side effects such as pancreatitis and liver toxicity.Formula:C16H16N2O6Purezza:Min. 95%Peso molecolare:332.32 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite
Nucleoside phosphoramidite used in oligonucleotide synthesisFormula:C49H58N5O10PPurezza:Min. 95%Peso molecolare:907.99 g/mol2-(Aminomethyl)pyrimidine oxalate
CAS:2-(Aminomethyl)pyrimidine oxalate is a substance that can be found in cicer arietinum. This compound has been shown to be tumorigenic, and it is hypothesized that the tumorigenicity of this compound is due to its ability to recombine with DNA and expressed genes, which may lead to the development of tumors. 2-(Aminomethyl)pyrimidine oxalate has been shown to activate translation of genes that are involved in tumorigenesis. The gene product which has been identified as being activated by 2-(aminomethyl)pyrimidine oxalate is called rhizogenes. Rhizogenes have been shown to have virulent phenotypes when exposed to cicer arietinum. With all these properties, it is believed that 2-(aminomethyl)pyrimidine oxalate may cause cancer or other harmful effects on organisms.br> br>Formula:C5H7N3·C2H2O4Purezza:Min. 95%Peso molecolare:199.16 g/mol2',3'-Cyclic guanosine monophosphate-adenosine monophosphate
CAS:cyclic guanosine monophosphate (cGMP) is increasingly recognized as having widespread consequences for human health which include regulation of biofilm formation as well as virulence. It has now been identified as a specific and high affinity ligand for the GEMM class of bacterial riboswitches that regulate gene expression.Formula:C20H24N10O13P2Purezza:Min. 95%Peso molecolare:674.41 g/molN-Benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-O-(2-methoxyethyl)adenosine
CAS:N-Benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-O-(2-methoxyethyl)adenosine is a synthetic nucleoside that is an activator of DNA polymerase and has antiviral activities. It is also used in the synthesis of deoxyribonucleosides, phosphoramidites, and ribonucleosides.Formula:C41H41N5O8Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:731.79 g/molBis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite
CAS:Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite is a potent inhibitor that targets human immunodeficiency virus (HIV) and cancer. It acts as an analog of substrates for human plasma membrane kinases, which are essential for the replication of HIV. Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite has been shown to inhibit lung metastasis in mice, indicating its potential therapeutic use against cancer. This compound also exhibits inhibitory activities against Escherichia coli alkaline phosphatase and other enzymes, suggesting its pharmacological activity may extend beyond HIV and cancer treatment. Overall, Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite is a promising inhibitor with potential applications in multiple fields.Formula:C12H22N3O2PPurezza:Min. 90 Area-%Colore e forma:Slightly Yellow Clear LiquidPeso molecolare:271.3 g/mol9-Deaza-2'-deoxyguanosine
CAS:9-Deaza-2'-deoxyguanosine is a novel synthetic nucleoside that activates the ribonucleotide reductase enzyme. The activation of this enzyme was found to be dependent on the presence of diphosphate, which is a cofactor for this enzyme. 9-Deaza-2'-deoxyguanosine has been shown to inhibit the growth of cells in culture and to induce apoptosis. It also inhibits viral replication by interfering with the synthesis of viral DNA. In addition, 9-Deaza-2'-deoxyguanosine can inhibit tumor cell proliferation and promote differentiation in vitro.Formula:C11H14N4O4Purezza:Min. 95%Peso molecolare:266.25 g/mol7-Deaza-7-iodoadenosine
CAS:7-Deaza-7-iodoadenosine is a nucleotide that has been used in experiments to assess the levels of adenosine, a dinucleotide phosphate that is involved in many cellular functions. 7-deaza-7-iodoadenosine has been shown to inhibit locomotor activity in rats and cyclase activity in 3T3-L1 preadipocytes. It also inhibits the release of inflammatory proteins from polymorphonuclear leucocytes and angiogenesis (formation of new blood vessels) in liver cells. Although this nucleotide has not been extensively studied, it has been proposed as an antiinflammatory agent because it inhibits protein synthesis and downregulates proinflammatory proteins.
Formula:C11H13IN4O4Purezza:Min. 95%Peso molecolare:392.15 g/mol5-Fluorouridine-5'-monophosphate sodium salt - 10mM aqueous solution
CAS:5-Fluorouridine-5'-monophosphate sodium salt is a nucleoside analog that is used as an antiviral drug. It inhibits viral DNA synthesis by competitive inhibition of thymidylate, which is a precursor for DNA synthesis. 5-Fluorouridine-5'-monophosphate sodium salt has been shown to be active against human pathogens and cancer cells in vitro. The enzyme activity of 5-fluorouridine-5'-monophosphate sodium salt can be inhibited by the presence of p-nitrophenyl phosphate, which is also a product of the enzymatic reaction. This may lead to synergistic effects in cells with both enzymes present.Formula:C9H12FN2O9PPurezza:Min. 95%Colore e forma:Colorless PowderPeso molecolare:342.17 g/mol2-Amino-4-(4-bromophenyl)pyrimidine
CAS:2-Amino-4-(4-bromophenyl)pyrimidine is a phosphoramidite, modified nucleoside. It is an antiviral and anticancer agent that inhibits DNA synthesis. 2-Amino-4-(4-bromophenyl)pyrimidine is a novel nucleotide analog with the ability to inhibit replication of RNA and DNA in vitro. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), cytomegalovirus (CMV), and HIV in cell culture. Furthermore, this phosphoramidite has been shown to have no detectable toxicity in mice at doses up to 2000 mg/kg.Formula:C10H8BrN3Purezza:Min. 95%Peso molecolare:250.09 g/mol5-Hydroxymethyl-dc ce-phosphoramidite (hmdc)
CAS:Please enquire for more information about 5-Hydroxymethyl-dc ce-phosphoramidite (hmdc) including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C50H57N6O9PPurezza:Min. 95%Peso molecolare:917 g/mol
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