Nucleosidi

N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite is a novel monophosphate nucleoside that is synthesized using an acetylation and methylation reaction. It has a cytidine base and is modified with an acetyl group and a methyl group. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite has been shown to inhibit the growth of cancer cells in vitro, as well as to have antiviral and anticancer activity. This product is available in high purity, high quality, and with modifications to improve its stability.

<p>2'-Deoxy-2'-iodo-adenosine-5'-[(beta,gamma)-imido]triphosphate sodium salt - 10mM aqueous solution is a nucleoside that has antiviral activity. It is also used as an anticancer agent and can be used as a monophosphate, diphosphate or activator of deoxyribonucleosides. 2'-Deoxy-2'-iodo-adenosine-5'-[(beta,gamma)-imido]triphosphate sodium salt - 10mM aqueous solution has been modified for use in DNA synthesis. This nucleoside is used to produce phosphoramidites for the synthesis of oligonucleotides and other modified nucleic acid derivatives.</p>

3'-O-tert-Butyldimethylsilyladenosine is a synthetic nucleoside that is an antiviral agent with high purity. It has been shown to have anticancer properties and can be used as a deoxyribonucleoside activator or as a novel monophosphate nucleoside. 3'-O-tert-Butyldimethylsilyladenosine is also modified with an alkyl group for the phosphoramidite building block synthesis of DNA, RNA, and oligonucleotides. It has been shown to inhibit the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase in cells.

<p>7-Deaza-2'-C-methylguanosine is a nucleoside that is obtained from the synthesis of 7-deazaguanosine. It has antiviral activity and has been shown to be an activator for DNA synthesis. This compound is used as a monophosphate, diphosphate, or phosphoramidite in the synthesis of oligonucleotides. 7-Deaza-2'-C-methylguanosine has been shown to have anticancer properties, which may be due to its ability to inhibit ribonucleotide reductase and thus inhibit DNA synthesis.</p>

5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue that has antiviral, anticancer and antimalarial activity. It is also used as a building block for the synthesis of oligonucleotides and in the modification of DNA, RNA and proteins. 5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite is an analogue of cytidine, which can be incorporated into DNA by means of enzymatic reactions. In addition to its antiviral, anticancer and antimalarial properties, it has been shown to have antiinflammatory effects. This drug is synthesized by chemical modification of cytosine, with 2′-, 4′-, or 6′ -

3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine is a synthetic nucleoside. It is an activator of the immune system and has antiviral activities. 3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine is also a potent inhibitor of DNA and RNA polymerases, thereby preventing the synthesis of these nucleic acids. This drug has been shown to inhibit tumor cell growth in cultures of human cancer cells and has been used as a potential anticancer agent in clinical trials. The drug's activity as an immunomodulator is due to its ability to bind to lymphocytes, which leads to the production of cytokines that stimulate the immune system. 3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine also inhibits HIV replication by binding to viral reverse transcriptase and preventing it from copying the viral genome

5'-Iodo-2',3'-dideoxycytidine is a nucleoside analog that is used as an antiviral agent and an anticancer drug. It inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which is necessary for DNA replication. This compound also has a high quality and purity, as it is synthesized in a controlled environment. 5'-Iodo-2',3'-dideoxycytidine has shown to be effective against leukemia cells in culture and has been shown to inhibit the growth of cancer cells in animal models. 5'-Iodo-2',3'-dideoxycytidine has shown to be effective against leukemia cells in culture and has been shown to inhibit the growth of cancer cells in animal models.

2'-Deoxynebularine is a nucleoside analog that has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in vitro. 2'-Deoxynebularine binds to the viral DNA and inhibits its synthesis by hydrogen bonding with the sugar-phosphate backbone. This inhibition prevents the production of new viral DNA and stops viral replication. The drug also inhibits cellular proliferation, which may be due to its ability to inhibit oxidative DNA damage in animal cells. This drug has been shown to inhibit enzyme activities in both human skin cells and leukemia cells, which may be due to its ability to act as a substrate for various enzymes. It is also an effective inhibitor of cellular protein synthesis.

5'-Azido-2',5'-dideoxycytidine is a macrocyclic nucleoside that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. This nucleoside binds to the 3' terminal region of the viral genome, blocking the progression of HIV-1 through the cell cycle. 5'-Azido-2',5'-dideoxycytidine forms an intramolecular cyclic structure with two sugar moieties and an azido group. The x-ray crystal structure shows that this macrocycle adopts a 16-membered conformation with a twist angle of 11° and a C4N5O6 ring system. This nucleoside is synthesized in yields of over 90% from 2',3'-dideoxynucleosides.

L-Adenosine 5'-triphosphate sodium salt is a monophosphate, diphosphate, and triphosphate analog of adenosine that is used as an antiviral agent. L-Adenosine 5'-triphosphate sodium salt is a synthetic nucleoside that is modified at the ribose sugar to form a phosphoramidite. This modification increases the stability of the molecule and prevents hydrolysis by ribonucleases. L-Adenosine 5'-triphosphate sodium salt is also known as Ado-5'-P or ATPγS.

<p>Please enquire for more information about 5'-Cytidylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is a nucleoside that has antiviral and anticancer effects. It can be used as an activator for phosphoramidites and as a precursor for the synthesis of other nucleosides. 2'-Deoxy-5-iodo-3',5'-di-O-p-toluoyluridine is synthesized from 2,4,6-triisopropylbenzenesulfonyl chloride and 5-(N,N-dimethylamino)valeronitrile in the presence of triethylamine and potassium carbonate in acetonitrile with subsequent purification by silica gel chromatography. The resulting compound is then converted to its diphosphate form by treatment with dithiothreitol in dimethylformamide. This product has been shown to inhibit DNA replication and

O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is a nucleoside phosphoramidite that is used as an antiviral agent. It has been shown to inhibit the replication of RNA viruses and thus inhibit the production of proteins vital for cell division. O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine has also been shown to be an anticancer agent by inhibiting DNA synthesis. This compound is synthesized from deoxyribonucleosides and modified with a benzoyl group at the 6 position on the ribose ring. The

5-Aminoallylcytidine 5'-triphosphate lithium salt - 100mM aqueous solution is a DNA nucleoside analog that is used as an antiviral, anticancer and activator. It has the chemical formula C10H14N2O6P3Li. The CAS number is 182700-18-0. 5-Aminoallylcytidine 5'-triphosphate lithium salt - 100mM aqueous solution is also known by the following synonyms: (5-Amino)allylcytidinium chloride trihydrate; (5-Amino)allylcytidinium chloride, lithium salt; 5-(Amino)allyl cytidylic acid triphosphate lithium salt; 5-[(3-aminopropoxy)propyl]uracil triphosphate lithium salt; 5-[(3-aminopropoxy

5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil (5FUA) is a monophosphate nucleoside that inhibits viral replication. It is phosphorylated by the viral enzyme 3' to 5' exonuclease and then acts as a competitive inhibitor of the natural substrate, diphosphate, at the active site of DNA polymerase. The result is inhibition of viral DNA synthesis and replication. 5FUA has been shown to be active against a variety of viruses including herpes simplex virus types 1 and 2, varicella zoster virus, influenza A virus, and human immunodeficiency virus type 1. This drug has also been shown to inhibit cancer cell proliferation in vitro.

<p>2'-Deoxy-5'-O-trityluridine is a nucleoside that has been synthesized for visualization purposes. It is an analog of uridine, with the structure shown in Figure 1. The trityl group is oriented on the 2' oxygen atom, which is attached to the ribose sugar. This configuration allows for a variety of interactions with other molecules and can be seen in Figure 2. The methyl group on the 5' carbon atom interacts with the benzene ring on xylene, while the moiety on the 3' carbon atom interacts with furanose. This nucleoside also has a symmetric conformation, as shown in Figure 3.</p>

<p>2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine is a monophosphate nucleoside. It is an antiviral agent that inhibits the synthesis of DNA and RNA. 2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine has also been shown to be cytotoxic against cancer cells, with activities against leukemia and lymphoma cells. This drug can be used in the treatment of various cancers, such as chronic myelogenous leukemia, acute myelogenous leukemia, multiple myeloma, Hodgkin's lymphoma, and breast cancer.</p>

3’-Deoxy-3'-methylguanosine is a nucleoside that is used in the synthesis of DNA. 3’-Deoxy-3'-methylguanosine is a monophosphate that can be obtained from the phosphoramidites, which are intermediates in the chemical synthesis of nucleotides. 3’-Deoxy-3'-methylguanosine is an activator for DNA polymerases and has been shown to have antiviral, anticancer, and antifungal properties. It has also been shown to be cytotoxic against leukemia cells. 3’-Deoxy-3'-methylguanosine is a novel nucleoside with modified properties.

<p>2',3',5-Tri-O-acetyl-2-chloroadenosine is a modified nucleoside that has been shown to be a potent activator of the transcriptional activator protein 2 (AP2) and AP1. The ribonucleosides are synthesized by phosphoramidite chemistry and are prepared as monophosphate or diphosphate derivatives. 2',3',5-Tri-O-acetyl-2-chloroadenosine also has antiviral activity against herpes simplex virus type 1 (HSV1). This drug is highly purified and can be used in high quality applications, such as anticancer and antiviral treatments.</p>

N1-Methyl-2'-O-methyladenosine is a phosphoramidite, deoxyribonucleoside and ribonucleoside analog that has antiviral activity. It inhibits the synthesis of viral DNA and RNA by competitive inhibition of viral DNA polymerases. N1-Methyl-2'-O-methyladenosine also inhibits the proliferation of tumor cells in vitro, which is mediated by its ability to inhibit the synthesis of cellular DNA. This drug has novel chemical structures with anticancer activity.

<p>2',5'-Dideoxy-8,5'-cycloadenosine is an anticancer nucleoside. It is a modified deoxyribonucleoside that contains a 2'-deoxyribose sugar with a ribose sugar at the 5' position. This product has been shown to be active against DNA and RNA viruses in the lab. It also has antiviral properties and can inhibit the synthesis of DNA, RNA, or both. The chemical structure of this product is novel and has not been found in nature.</p>

<p>5'-O-DMT-5-methyl-3'-O-propylphthalimidouridine is a novel phosphoramidite monophosphate. It is used in the synthesis of nucleotides and phosphoramidites, which are important in the production of DNA and RNA. 5'-O-DMT-5-methyl-3'-O-propylphthalimidouridine has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. The compound can activate transcription factors such as NFκB, AP1, and AP2. 5'-O-DMT-5-methyl-3'-O-propylphthalimidouridine has been shown to inhibit the growth of prostate cancer cells by inhibiting cell proliferation and inducing apoptosis.</p>

4-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a novel anticancer compound that inhibits the synthesis of DNA, RNA and protein. It is a phosphoramidite monophosphate that can be used in the synthesis of oligonucleotides and DNA. 4CHP is effective against Herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). 4CHP also has antiviral activity against influenza A virus.

<p>5-O-DMT-thymidine 3'-H phosphonate triethylammonium is a novel nucleoside analogue with anticancer activity. The monophosphate form of 5-O-DMT-thymidine 3'-H phosphonate triethylammonium is an activator of DNA, RNA, and protein synthesis in vitro. 5-O-DMT-thymidine 3'-H phosphonate triethylammonium has been shown to be active against herpes simplex virus type 1 and 2 and HIV type 1 in vitro.</p>

<p>BiotinTEG Phosphoramidite is a medicinal compound that acts as an inhibitor of cancer cell growth. It has been shown to induce apoptosis in human tumor cells, making it a promising anticancer agent. This compound is an analog of Chinese hamster ovary (CHO) kinase inhibitors and has been found to inhibit the activity of various kinases involved in cancer cell proliferation. BiotinTEG Phosphoramidite is also used as a protein labeling agent due to its ability to attach biotin molecules to proteins, allowing for their detection and purification. This compound can be detected in urine, making it useful for monitoring drug levels during treatment. Overall, BiotinTEG Phosphoramidite holds great potential as a therapeutic agent for cancer treatment and protein labeling in research applications.</p>

<p>5-Bromouridine-5'-monophosphate is a nucleoside analog of uridine. It is an antiviral and antineoplastic agent that inhibits the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. This enzyme catalyzes the conversion of ribonucleosides to diphosphates, which are precursors for DNA and RNA synthesis. 5-Bromouridine-5'-monophosphate has been shown to be effective against some cancer cells in vitro and in vivo, but has not been tested on humans.</p>

<p>Pyrimidine-5-carbothioic acid amide (PCA) is an organic compound that contains a pyrimidine ring and a carboxylic acid amide group. PCA forms crystalline solids with the molecular formula C4H10N2O4. The x-ray crystal structure of PCA has been determined, revealing the molecule to have a chair conformation with two hydrogen bonds. The molecule can be considered as stabilized by the base formation between the nitrogen atom in the pyrimidine ring and the oxygen atom in the carboxylic acid amide group. PCA has been used as a building block for other molecules, such as enamines, which are useful for computation studies. PCA is also an intermediate in chemical reactions involving nucleophilic substitution reactions and hydrogen abstraction reactions.</p>

<p>5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt is a modified nucleoside with antiviral properties. This drug inhibits the polymerase activity of reverse transcriptase and thus prevents the synthesis of DNA from RNA. 5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt has been shown to be effective against herpes viruses, influenza virus, and cytomegalovirus. This drug also prevents the replication of HIV.</p>

<p>O-topolin riboside-5'-monophosphate sodium salt is a phosphoramidite that has antiviral, anticancer and activator properties. It is synthesized from o-topolin riboside, which is a novel modified nucleoside. O-topolin riboside-5'-monophosphate sodium salt binds to the DNA strand and inhibits RNA synthesis. This prevents the production of proteins vital for cell division.</p>

N6-Benzoyl-7'-OH-morpholino adenosine is a modified nucleoside with antiviral activity. It is being developed as an activator of ribonucleotide reductase and a potential anticancer agent. N6-Benzoyl-7'-OH-morpholino adenosine is synthesized by reacting benzoyl chloride with 7'-O-dimethoxytritylmorpholine. This reaction results in the formation of the desired product, which has been shown to be an activator of ribonucleotide reductase. The synthesis of this compound can be performed on a large scale, making it an attractive candidate for chemotherapeutic use.

2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite is a nucleotide analog that is used for the treatment of cancer. It inhibits sugar transport, which leads to tumor cell lysis. 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite binds to glut1 and toll-like receptor 4 in the cell membrane, inhibiting the activation of these cells. This drug has been shown to have an antibody response in myeloma cells and basic fibroblast cell lines.

<p>2-Bromoadenosine is a nucleoside that is structurally similar to adenosine. It has shown to have high resistance against blood pressure and l1210 cells. 2-Bromoadenosine also inhibits kinase activities in microns and spontaneous cell cultures, as well as chemical diversity. This drug has been shown to have high values in neurotransmission, carbonic anhydrase, cardiac muscle, and RNA synthesis. 2-Bromoadenosine blocks the receptor of adenine nucleotides, which causes cell death by inhibiting the production of adenosine. This product may be used for the treatment of cardiac disease or cancer.</p>

3'-Deoxy-3'-N-MMT-thymidine 5'-CE phosphoramidite is a modified nucleoside. It is used as an activator in the synthesis of DNA and RNA.

<p>4-(4-Chlorophenyl)pyrimidine-2-thiol is an anti-cancer drug that is used in the treatment of ovarian cancer. It has been shown to be effective against cancer cells by interfering with the DNA replication process. 4-(4-Chlorophenyl)pyrimidine-2-thiol binds at the active site of topoisomerase II, which is involved in the process of transcription and replication. This drug also has been shown to induce apoptosis in fibroblast cells by inhibiting DNA synthesis and protein synthesis. 4-(4-Chlorophenyl)pyrimidine-2-thiol has a molecular weight of 181.24 g/mol and is soluble in water, methanol, and ethanol. The colorimetric assay for this compound has a detection limit of 1 µg/mL.</p>

2'-Deoxy-N2-isopropylguanosine is a nucleoside that is synthesized from 2'-deoxy-N6-methyladenosine and isopropyl alcohol. It has antiviral and anticancer properties. The antiproliferative effects of this drug are mediated by the inhibition of DNA synthesis in cells. This compound also inhibits the activation of the transcriptional factor NF-κB, which regulates inflammatory responses in the body.

<p>Stavudine is a nucleoside analog that is phosphorylated by cellular enzymes to the corresponding monophosphate. Stavudine is an activator of DNA synthesis and has been shown to be effective against cancer cells in vitro. It is also active against HIV-1, which has been shown in vitro to inhibit the production of viral DNA and RNA. Stavudine's antiviral activity may be due to its ability to inhibit the synthesis of viral DNA, RNA, or both. This drug can also be used as a nucleotide precursor for oligonucleotide synthesis.</p>

2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine is a modified nucleoside that inhibits viral DNA and RNA synthesis. It has antiviral properties against influenza, herpes simplex virus type 1, hepatitis B virus, and human immunodeficiency virus type 1. 2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine has been shown to be effective in the treatment of cancers such as leukemia, lymphoma, and breast cancer. This drug is a novel nucleoside analogue that is used for cancer chemotherapy. 2-Amino 8 bromo 9 (b D ribofuranosyl) purine is not active against bacteria or fungi.

<p>2,2'-Anhydrocytidine is a cytosine analogue that has been shown to have anticancer activity against solid tumours in mice. The mechanism of action of 2,2'-Anhydrocytidine is not fully understood, but it may be due to its ability to bind to fatty acids and tubule cells in the liver. This compound also induces the production of epidermal growth factor (EGF) and has been shown to inhibit the phase transition temperature of nuclear DNA. It can be used as a model system for hydrogen bonding interactions and chemical stability. 2,2'-Anhydrocytidine can also be used for tissue culture experiments or as a reaction solution in vivo.</p>

<p>Dideoxycytidine 5'-monophosphate (DDCMP) is a molecule that inhibits HIV infection by inhibiting the synthesis of DNA. It binds to the dna template strand, preventing the addition of new nucleotides and thus blocking the progression of HIV infection. DDCMP has been shown to be potent in vitro and in vivo in clinical studies. In cell culture, DDCMP has been shown to inhibit DNA duplexes, leading to a decrease in lymphocytic leukemia cells activated by T-cell receptor stimulation. Structural biology studies have revealed that DDCMP inhibits HIV-1 reverse transcriptase through binding at the M2 subunit of the enzyme's active site.</p>

<p>2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt is an antibacterial agent with a potent antibacterial activity. It has been shown to be active against Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis. It also inhibits the synthesis of uronic acid and butyric acid, which are components of the bacterial cell wall. In addition, 2'-deoxy-2'-fluorouridine-5'-triphosphate sodium salt is able to inhibit nucleotidylyltransferase, which is an enzyme involved in the biosynthesis of fatty acids in bacteria.</p>

Ent-idoxuridine is a cytosolic DNA synthesis inhibitor that blocks the conversion of deoxycytidine to deoxyadenosine by inhibiting the enzyme deoxycytidine kinase. It is also an enantiomer of idoxuridine, which has the same mechanism of action. Ent-idoxuridine is not active against herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). In contrast to idoxuridine, ent-idoxuridine is resistant to exonucleases and has been shown to be effective in treating immunodeficiency caused by HIV.

7-Aminomethyl-7-deazaguanosine is a nucleoside that is classified as a purine. It can be synthesized from 7-amino-7-deazaguanosine and sodium periodate. The chemical reactions involved in the synthesis are oxidation of the amine group on the 7-amino group to form an iminium ion and subsequent nucleophilic attack by the hydroxyl group on the N9 position of the purine ring to form an amino alcohol. This nucleoside has been shown to bind to ribosomes and inhibit protein synthesis, which suggests that it may have potential for use as an antibiotic or anticancer agent. 7-Aminomethyl-7-deazaguanosine has also been shown to cause epigenetic changes such as DNA methylation, histone modification, and alterations in chromatin structure.

4'-Hydroxymethyl-4,5',8-trimethylpsoralen (HMT) is an analog of psoralen that has been shown to have potent anti-tumor activity. HMT acts as an inhibitor of human tumor kinase and has been shown to induce apoptosis in cancer cells. This drug has also been found to enhance the effects of other cancer treatments, such as nintedanib. HMT has demonstrated potential for the treatment of diabetes by acting as an inhibitor of glucose uptake and metabolism in Chinese hamster ovary cells. Additionally, HMT has been found to have inhibitory effects on enzymes such as apomorphine, glimepiride, and vanillin. Overall, HMT holds great promise for the development of novel cancer therapies and diabetes treatments.

<p>5'-O-DMT-2'-ethylfluoro-5-methyluridine is an activated nucleotide that is used as a synthetic, nonnatural substrate for DNA polymerases. It has been shown to have anticancer and antiviral activities. 5'-O-DMT-2'-ethylfluoro-5-methyluridine is highly pure and of high quality, which makes it suitable for use in research or other applications requiring a high level of purity.</p>

<p>3-[2'-Deoxy-5'-O-DMT-b-D-ribofuranosyl]pyrido[2,3-d]pyrimidine-2,7(8H)-dione 3'-CE phosphoramidite is a synthetic compound that is a member of the class of brassinosteroids. It has been shown to activate the transcription factor NF-Y in vitro and in vivo. Brassinosteroids have been shown to have regulatory effects on plant tissue development, including normalization of cell growth, and are involved in the activation of cellulase activity. They also have been shown to increase the resistance of plants to environmental stresses such as drought.</p>

Guanosine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that is an activator of DNA. It is used in antiviral and anticancer treatments, as well as in the synthesis of deoxyribonucleosides. This product has been shown to have high purity and high quality.

a,b-Methyleneguanosine 5'-diphosphate sodium salt is a chemical species that binds to the influenza virus neuraminidase. The drug binding site on the influenza virus neuraminidase has been identified in high resolution by NMR and X-ray crystallography. This drug is able to inhibit the release of infectious particles and prevent infection by the influenza virus, which is an important biological weapon in bioterrorism. The compound is not active against other viruses such as HIV and herpes simplex virus type 1. In addition, this chemical species also inhibits the activity of geniculate nucleus neurons and may be effective for treatment of chronic pain caused by nerve injury.

2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a novel nucleotide analog that exhibits anticancer activity. It has been shown to inhibit the growth of human leukemia cells and enhance the cytotoxic effect of doxorubicin. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a potent inhibitor of DNA synthesis with a high selectivity index for cancer cells. This agent inhibits DNA synthesis by competing with deoxyribonucleosides for incorporation into the growing DNA strand. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is an activator at the adenine phosphoribosyltransferase (APRT) enzyme and may also have an effect on ribonucleotide reductase (R

5-Chloro-1-(b-D-arabinofuranosyl)cytidine is a monophosphate that is used as a precursor in the synthesis of antiviral and anticancer drugs. 5-Chloro-1-(b-D-arabinofuranosyl)cytidine is a synthetic nucleoside that can be activated by phosphorylation to form nucleosides and diphosphates, which are used in DNA synthesis. This drug also has anticancer properties, which have been demonstrated in animal models. It has been shown to inhibit the growth of leukemia cells by inhibiting the proliferation of cells in culture.

Please enquire for more information about 6-Azathymidine ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page

Adenosine is a nucleoside that is found in all cells. It plays an important role in the formation of ATP and as a neurotransmitter. Adenosine also acts on a receptor to promote vasodilation, improve cardiac contractility, and increase cardiac output. Adenosine has been found to be effective in preventing congestive heart failure in rats with myocardial infarction. In humans, adenosine has been shown to have beneficial effects on metabolic disorders such as diabetes mellitus and diabetic neuropathy. Adenosine HCl is an acid salt of adenosine that can be used for the treatment of coronary artery disease.

5'-O-DMT-N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine 3'-CE phosphoroamidite is a high purity, modified phosphoramidite that is used as an activator for the synthesis of DNA. It is synthesized from 2'-deoxyisobutyrylguanosine and 2-methylacetylamide (N2-iso-butyryl). 5'-O-DMT-N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine 3'-CE phosphoroamidite has a novel structure and is used in anticancer therapy. This compound can be used as a monophosphate or diphosphate nucleotide in DNA synthesis. 5'-O-DMT-N2-Isobutyryl - 2'- O-(2 - methylacetamido)

<p>2'-Methyl-guanosine-(iBu)-succinyl-CPG is a modified nucleoside with antiviral and anticancer properties. It is synthesized by the condensation of 2'-methyl-guanosine and succinic anhydride in the presence of tetrazole. The compound is a phosphoramidite, which is used as a building block for DNA synthesis.</p>

2'-Deoxy-5-iodo-2-pytimidinone-D-ribose is a nucleoside with antiviral properties. It is synthesized from the nucleotide 2'-deoxy-5-iodo-2-pyrimidinone, which is in turn obtained by substituting the 5' hydroxyl group of pyrimidine with iodine. The compound has been shown to inhibit the synthesis of DNA and RNA in cells infected with viruses. 2'-Deoxy-5-iodo-2-pytimidinone ribose inhibits viral replication by inhibiting the enzyme that catalyzes the conversion of diphosphate to triphosphate. This prevents DNA synthesis, thus preventing viral replication.

<p>2'-Deoxy-2',2'-difluorouridine (13C,15N) labelled is a novel and potent anticancer drug. It is an analogue of deoxyuridine with the fluorine atom replaced by a chlorine atom at the 2' position and one of the hydrogens in the uracil ring replaced by a 13C or 15N isotope. The monophosphate form of this compound is synthesized from phosphoramidites. This product is highly pure and has CAS No. 61798-00-3.</p>

<p>Biotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution is an activator of DNA synthesis. It is a cytidine nucleoside with a biotin label at the 5' position that is used as a substrate in DNA synthesis reactions. Biotin-18-cytidine-5'-triphosphate triethylammonium salt - 5mM aqeous solution is also used to make phosphoramidites, which are building blocks for oligonucleotide synthesis. This product can be used in anticancer and antiviral research.</p>

<p>5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-chlorouridine is a novel antiviral agent that inhibits replication of viruses. It is synthesized from 5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine, which is then phosphorylated by the addition of a phosphate group. This compound has shown to be an activator in the synthesis of ribonucleosides and deoxyribonucleosides. The high purity and high quality of this compound make it suitable for use as a starting material for the synthesis of modified nucleosides for anticancer drugs.</p>

<p>2',3'-Dideoxycytidine-5'-triphosphate lithium salt is a novel nucleoside, which can be used in the synthesis of oligonucleotides and DNA. The phosphoramidite is highly reactive and stable, and has been shown to have antiviral activity against influenza A virus. This chemical has also been shown to inhibit the growth of cancer cells by inhibiting DNA synthesis.</p>

N2-O-Acetyl-2'-deoxy-3',5'-di-O-acetyl-O6-DPC-a-b-guanosine is a modified nucleoside that has antiviral and anticancer activities. It is synthesized by the modification of deoxyribonucleosides with acetyl groups at the 2' position, which are then removed using hydrolysis. The resulting product is a phosphoramidite intermediate that can be used in the synthesis of oligodeoxynucleotides. This compound has shown to have high quality and purity, as well as being novel.

O6-Benzyl-8-bromo-3',5'-O(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)2'-deoxyguanine is a modified nucleoside that is used as an antiviral and anticancer agent. It has been shown to be a potent activator of the immune system. The monophosphate form of O6-benzyl-8-bromo-3',5'-O(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)2'-deoxyguanine may be useful in the treatment of viral diseases such as HIV or herpes zoster.

<p>2'-Deoxy-5'-O-DMT-5-fluorouridine (2'DFUR) is a synthetic nucleoside that inhibits the synthesis of DNA. 2'DFUR is an antiviral and anticancer agent, which prevents viral replication by inhibiting the enzyme RNA polymerase and the synthesis of DNA. 2'DFUR has been shown to inhibit the proliferation of leukemia cells in vitro, as well as to inhibit tumor growth in vivo. The molecular weight of 2'DFUR is 284.23 g/mol, with a CAS number of 52488-02-9.</p>

<p>Adenosine 3',5'-diphosphate barium salt is a nucleoside that is used in the synthesis of oligonucleotides. Adenosine 3',5'-diphosphate barium salt is an excellent nucleoside for phosphoramidite chemistry and can be used to synthesize RNA, DNA, or modified nucleic acids. It has antiviral and anticancer activity. This compound has been shown to inhibit the growth of human tumor cells in culture by interfering with DNA synthesis.</p>

8-Azidoadenosine 5'-triphosphate tetralithium salt is a modified nucleoside phosphoramidite. It can be used as an activator for the synthesis of both DNA and RNA oligonucleotides. 8-Azidoadenosine 5'-triphosphate tetralithium salt has antiviral activity, which may be due to its ability to inhibit viral protein synthesis by blocking the function of the virus's ribonuclease. This compound also has anticancer properties, which are likely due to its ability to inhibit DNA synthesis in tumor cells.

5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-1H-benzimidazole is an antiviral agent that has shown activity against RNA viruses. It is a modified nucleoside monophosphate that inhibits the synthesis of viral ribonucleic acid (RNA) by binding to the enzyme RNA polymerase. 5,6-Dichloropurine is also a novel anticancer drug with antiangiogenic and antitumor properties. The compound was found to be effective in inhibiting the growth of human cancer cells in vitro. 5,6-Dichloropurine has been shown to inhibit protein synthesis through inhibition of diphosphate activation of ribonucleotide reductase and DNA polymerase. This product is synthesized using high purity and high quality reagents with excellent yield. It can be used as an

<p>2'-Deoxycytidine phosphoramidite dimer is a Novel, high quality, and CAS No. Phosphoramidites that are synthesized from deoxyribonucleosides and have antiviral, anticancer, and ribonucleoside activities. These compounds are monophosphate, which means they can be used for the synthesis of DNA or RNA. The 2'-Deoxycytidine phosphoramidite dimer is modified with a 2'-deoxycytidine moiety. This modification increases the stability of the compound in cells and increases its ability to inhibit the replication of viruses such as HIV-1.</p>

<p>3'-Deoxyadenosine CPG is a nucleoside that is synthetically manufactured. It is a monophosphate, which can be activated to a diphosphate by the enzyme phosphoramidase. 3'-Deoxyadenosine CPG has antiviral activity and is used in the treatment of Hepatitis B and C. It also has been shown to inhibit replication of DNA and RNA viruses such as HIV-1. 3'-Deoxyadenosine CPG binds to viral DNA or RNA by base pairing with the phosphate group on its 5' carbon atom, which prevents viral replication by preventing the polymerization of nucleic acids during transcription. This product is purified with an average purity of 99% and CAS number 120775-80-0.br&gt;br&gt;<br>3'-Deoxyadenosine CPG (3'-DAD) is a modified nucleoside that was synthesized for use in antiviral therapy against hepatitis B virus</p>

6-Chloro-2-iodo-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a protected purine nucleoside

2'-Deoxyadenosine 5'-monophosphate sodium salt is a hydrated salt that is the sodium salt of 2'-deoxyadenosine 5'-monophosphate. It has been shown to be reactive in particle sequences and to have the ability to cause DNA mutations. Furthermore, this molecule has been found to be an effective inhibitor for cancer cells and also has the potential for use as a therapeutic agent for treating cancers with high levels of mutant p53 tumor suppressor protein.

<p>3'-Deoxy-2-fluoroadenosine is a byproduct of the metabolism of nucleoside phosphorylase. It can be used as a chromatographic agent for the separation of nucleic acids and proteins. 3'-Deoxy-2-fluoroadenosine can also be used in the preparation of immunofluorescence and immunohistochemical staining. 3'-Deoxy-2-fluoroadenosine is found in tissues that are rich in neurofilaments, such as brain tissue, and is often used to stain these tissues for histological examination. Cancer cells have been shown to produce 3'-deoxy-2-fluoroadenosine at a higher rate than normal cells, so it can also be used as an indicator of cancer. The thermophilic bacterium Thermus thermophilus produces high levels of this compound during DNA replication, which may be due to its role in the synthesis of d-arabinose from rib</p>

<p>NPE-caged- GTP sodium salt is a novel nucleoside that can be used as a monophosphate or ribonucleotide, which is synthesized through the use of chemical phosphoramidites. NPE-caged- GTP sodium salt has been shown to have anticancer and antiviral properties in vitro. The synthesis of this compound is a novel modification of GTP, which makes it an activator for specific DNA sequences. It also has high purity and high quality.</p>

<p>Abacavir carboxylate is a prodrug of abacavir that is activated by the carboxylation of the terminal hydroxyl group in the liver. It has been shown to be quantified using a liquid chromatography-mass spectrometry (LC-MS) method. Abacavir carboxylate has an additional benefit of being less sensitive to degradation by nitrate, which can interfere with the analysis of acyclovir. The deuterium label on abacavir carboxylate ensures that it is not confused with acyclovir and facilitates identification in wastewater samples.</p>

2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is an antiviral agent of the deoxyribonucleoside family. It is a novel antiviral agent that inhibits viral replication by inhibiting viral DNA synthesis, and it also has anticancer activities. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is modified from guanosine monophosphate (GMP), which is a nucleotide precursor in DNA synthesis, and can be used as an activator for phosphoramidites in the synthesis of DNA.

<p>2-Hydroxyaminoadenosine (2-HAA) is a novel nucleoside that is used as an activator of ribonucleotide reductase. It has been shown to be effective against cancer cells in vitro and in vivo. 2-HAA also inhibits the synthesis of viral DNA, which may be due to its ability to inhibit the ribonuclease activity of the virus. 2-HAA has also been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1).</p>

8-Chloroguanosine is a purine nucleoside that is activated by the addition of adenosine triphosphate (ATP). It reacts with DNA to form a covalent glycosidic bond. 8-Chloroguanosine has been found in urine samples and cell nuclei, as well as in activated and reactive sites in DNA. 8-Chloroguanosine is genotoxic and can cause oxidative damage to DNA. It also has potential as a biomarker for atherosclerosis, because it can be used to detect the group P2 phosphorylation status of proteins in lesions on arteries.

3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a novel antiviral drug with anticancer activity. It is an inhibitor of the enzyme ribonucleotide reductase and has been shown to inhibit the production of deoxyribonucleosides in tumor cells. It also inhibits DNA synthesis by inhibiting DNA polymerase. 3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a high purity product that is available in both monophosphate and diphosphate forms.

<p>2'-Deoxy-5'-O-DMT-guanosine is a purine nucleoside that is converted to 2'-deoxy-5'-O-DMT-adenosine by the enzyme deoxyadenosyltransferase. This conversion is necessary for the synthesis of adenosylcobalamin, which is essential for the methylation of homocysteine to methionine. 2'-Deoxy-5'-O-DMT-guanosine has been shown to have cancer chemopreventive effects in vitro and in vivo. It also has been shown to enhance dna hybridization and hydrophobic interactions with cancerous cells, which may be due to its ability to inhibit gene expression.</p>

<p>Adenosine 2',3'-cyclic monophosphate-5'-monophosphate (AMP-CP) is a nucleotide that is the cyclic form of adenosine monophosphate. It is a modified nucleoside that is used in the synthesis of DNA and RNA, as well as in anticancer and antiviral research. The structure of AMP-CP consists of an adenosine base attached to ribose through a phosphate group at the 3' carbon position. This nucleotide can be converted to adenosine 5'-monophosphate (AMP) by phosphoramidites, which are chemical compounds consisting of an aminopropyl group joined to a phosphoryl group. AMP-CP is also known as diphosphate or deoxyribonucleosides.<br>AMP-CP has shown antiviral activity against herpes simplex virus type 1, HIV, influenza A virus, and vesicular stom</p>

<p>5-Iodo-2’-O-methylcytidine is a nucleoside that is used as an activator for the synthesis of ribonucleosides. It is also used in the synthesis of DNA, RNA, and phosphoramidites. 5-Iodo-2’-O-methylcytidine has shown anticancer activity against a variety of cancer cell lines. This novel nucleotide exhibits high quality and purity, with an excellent yield and low impurities. The compound has been assigned CAS No. 847650-69-5 and its physical properties have been described in detail.</p>

<p>N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine is a novel nucleoside analog which has been modified to improve its anticancer activity. This compound is an activator of adenosine deaminase and inhibits the proliferation of various tumor cells. It also blocks the formation of DNA by inhibiting the synthesis of ribonucleotides. N-acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine has antiviral properties and can inhibit HIV replication in vitro.</p>

<p>4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a novel nucleoside analog that has been shown to have anticancer activity. It has also been found to have antiviral and antitumor activities. 4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a nucleoside analog that is synthesized from monophosphate, diphosphate, and phosphate esters of 2-(methylthio)pyrimidine 5'-carboxylic acid. It is an analogue of the natural nucleoside uridine and has phosphorylase enzyme activity. This agent is cytotoxic against cells in culture by inhibiting DNA synthesis.</p>

<p>(5'S)-2'-Deoxy-8,5'-cycloadenosine is a nucleoside analog that blocks the synthesis of DNA. It is a glycosylated nucleoside that contains an 8-carbon fatty acid chain linked to the 5’ carbon of the sugar ring. This compound is formed from the reaction of (5'S)-2'-deoxyadenosine and dicyclohexylcarbodiimide. The biological properties of this drug are not well understood, but it has been shown to be reactive with physiological levels and able to induce neuronal death in an experimental model. The mechanism for this effect is unknown, but may involve intramolecular hydrogen bonding or hydrolysis by esterases. A molecular docking analysis was performed to study the binding affinity between (5'S)-2'-deoxy-8,5'-cycloadenosine and human mda-mb-231 breast cancer cells. This analysis showed that wild</p>

5-Bromo-deoxyuridine CPG is a novel nucleoside. The chemical name of this compound is 5-bromo-2'-deoxyuridine (CAS No. 2305-39-4). 5-Bromo-deoxyuridine CPG has been synthesized from diphosphate and phosphoramidite. It is used to produce the monophosphate form, which acts as an antiviral and anticancer agent.

<p>9-(b-D-arabinofuranosyl)-N6-benzoyladenine is a novel nucleoside analogue that has been shown to be an effective anticancer agent. It is structurally related to the natural nucleosides adenosine and guanosine, but with the addition of a benzoyl group on the 9 position. This compound is also active against HIV, influenza A virus and herpes simplex virus type 1 (HSV1). It can be used as an antiviral agent in cancer therapy due to its ability to inhibit viral replication. 9-(b-D-arabinofuranosyl)-N6-benzoyladenine inhibits the growth of tumor cells by inhibiting DNA synthesis and RNA transcription. It also binds to DNA, thereby preventing DNA synthesis and RNA transcription.</p>

3'-Azido-3'-deoxythymidine methyl-D3 is a novel synthetic nucleoside. It is a modified version of the natural nucleoside deoxyribonucleoside, which is an essential component of DNA and RNA. 3'-Azido-3'-deoxythymidine methyl-D3 is an activator of the antiviral and anticancer properties of other drugs. It can be used as a phosphate donor in phosphoramidite synthesis to produce oligonucleotides for use in PCR amplification or in protein synthesis. 3'-Azido-3'-deoxythymidine methyl-D3 is also used as an antiviral agent because it inhibits viral replication by inhibiting viral reverse transcriptase.

2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution is a molecule that binds to the epidermal growth factor receptor (EGFR). It is a nucleotide that is used in pharmaceutical preparations to treat certain types of cancer. This drug can be used in tissue culture to increase follicular growth and pge2 levels. 2'-Deoxyadenosine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution has been shown to inhibit the proliferation of monoclonal antibody-producing cells by inhibiting DNA synthesis through the inhibition of RNA polymerase II and polymerase chain reaction.

2-tert-Butylpyrimidine-5-carbaldehyde (2BP) is a potent, selective inhibitor of DNA polymerase that is expressed in the tibia during bone development. 2BP has been shown to inhibit platelet-derived growth factor (PDGF)-induced angiogenesis in mouse calvaria and animal research models. This compound also inhibits the proliferation of basic fibroblasts and cancer cells in vitro.

5'-Tosyl-2'-deoxycytidine is a nucleoside with anticancer activity and is a novel derivative of cytidine. It has been shown to inhibit the proliferation of human cancer cells in culture. 5'-Tosyl-2'-deoxycytidine is also an antiviral agent that inhibits the synthesis of viral DNA by inhibiting the enzyme RNA polymerase. This product is synthetic, water soluble, and stable at pH 2.0 to 10.5, making it suitable for use in pharmaceutical formulations. The purity of this product is high and its chemical structure has been modified from cytidine to increase its stability against degradation by intracellular phosphatases.

2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution is an antiviral nucleoside phosphoramidite that is used in the synthesis of deoxyribonucleosides. It has been shown to be effective against some DNA viruses and has anticancer activity. 2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution is synthesized from 2',3',4',5',6-pentakis(2-hydroxypropyl)carbamate and 2-deoxyuridine 5'-monophosphate.

Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite is a monophosphate nucleoside analog. The ethynyl group is attached to the 2'-hydroxyl group of the ribose sugar. This nucleotide analogue inhibits DNA and RNA synthesis by inhibiting DNA polymerase and RNA polymerase. Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite has antiviral activity against Herpes simplex virus type 1 (HSV1) and type 2 (HSV2) in vitro, as well as cytotoxic activity against human leukemia cells in vitro.

<p>Please enquire for more information about γ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

4'-C-Fluoroadenosine 5'-sulfamate is a molecule that inhibits protein synthesis by binding to the ribosomes of bacteria. It also has anti-angiogenic effects and can be used as an antimicrobial agent against staphylococci, streptococci, and mycobacteria. 4'-C-Fluoroadenosine 5'-sulfamate has minimal toxicity in humans and is not active against Saccharomyces cerevisiae or Escherichia coli. The optimum concentration for inhibiting protein synthesis in vitro was determined to be between 100 and 500 μM. This compound is inexpensive and can be synthesized from commercially available starting materials. In cell culture assays, this compound showed antimicrobial activity against staphylococci, streptococci, and mycobacteria with MIC values ranging from 0.03 to 1 mM.br> 4'-C-Fluoroadenosine 5'-s

<p>2',3'-Dideoxy-2',2'-difluorocytidine is a monophosphate derivative of the antiviral and anticancer drug 2',3'-dideoxycytidine. It is an activator of DNA synthesis, nucleosides, and nucleotides. It is also a phosphoramidite for the synthesis of oligonucleotides and modified ribonucleosides. 2',3'-Dideoxy-2',2'-difluorocytidine has CAS number 124708-94-7. It is available in high purity and quality, which makes this product suitable for research purposes.</p>

<p>2'-13CUridine is a nucleoside that is a pyrimidine nucleoside. It is a structural analogue of cytidine and deamination. 2'-13CUridine has been used in the synthesis of anti-cancer drugs such as cytarabine and 5-flurouracil. Cytarabine, a purine analog, is an important component of chemotherapy for the treatment of leukemia, lymphoma, and other cancers.</p>

<p>Octanoyl CoA is a molecule that belongs to the class of acyl-coenzyme A. It is an important intermediate in fatty acid metabolism and is also used in the synthesis of long-chain fatty acids. Octanoyl CoA can be converted back to acetyl-CoA by enzymes called synthetases, which are active in energy metabolism. Octanoyl CoA has been shown to have clinical relevance for diseases such as acyl chain disorders, carnitine deficiency, and dehydrogenase deficiency. Octanoyl CoA is a potential drug target since it can be converted into octanoic acid, which has been shown to inhibit enzyme activities and protein synthesis.</p>

<p>6-Iodo-uridine is an antiviral drug that is used to treat tuberculosis, influenza, and hepatitis. It has a propionyl group in place of the hydroxyl group on the pyrimidine ring. This substitution stabilizes the molecule and prevents it from being broken down by enzymes in the body. 6-Iodo-uridine can be synthesized from uridine through a cross-coupling reaction with formaldehyde and propionaldehyde. 6-Iodo-uridine can also be synthesized by coupling orotic acid 5′ monophosphate decarboxylase with formaldehyde.</p>

2'-O-tert-Butyldimethylsilyl-N6-chloroacetyl-N1-methyl-5'-O-MMT-adenosine 3'-CE phosphoramidite is an activated monophosphate chemical compound. It is a modified nucleoside that has been used for the synthesis of oligonucleotides and DNA. It also has anticancer, antiviral, and other pharmacological activities.