
Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
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N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt
CAS:N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt is a monophosphate nucleoside that has been modified with a 6-aminohexylaminocarbonyl group. It is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and proteins. N6-[(6-Aminohexyl)carbamoylmethyl]adenosine 5'-triphosphate lithium salt is novel and high quality.Formula:C18H32N7O14P3·xLiPurezza:Min. 95%5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite
<p>5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a nucleoside which is an activator for DNA synthesis. It is synthesized from the natural substance thymidine, and it can be modified to have various properties by changing the chemical group that attaches to the 3' carbon. 5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a novel nucleoside that has been shown to be anticancerous in vitro. This compound may also play a role in treating viral infections due to its antiviral properties.</p>Formula:C25H45N4O6PSiPurezza:Min. 95%Peso molecolare:556.72 g/mol2-Deoxy-2-fluoro-b-D-arabinofuranosylamine
CAS:2-Deoxy-2-fluoro-b-D-arabinofuranosylamine (2DF) is a monophosphate nucleoside analog that is chemically modified to form 2DF. The 2DF has shown antiviral, anticancer, and anti-inflammatory activities. It inhibits the proliferation of cancer cells by blocking the synthesis of DNA and RNA, which are necessary for cellular reproduction. This drug also has been shown to have an activator effect on diphosphate nucleotide incorporation into DNA.Formula:C5H10FNO3Purezza:Min. 95%Peso molecolare:151.14 g/molFluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-tr
<p>Fluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-triphosphate] is a modified nucleoside analog that is used as an antiviral agent against herpesviruses. This compound is phosphorylated by the virus encoded thymidine kinase, which converts it to the monophosphate form. Fluorescein-5(6)-carboxamidocaproyl-[5(3-aminoallyl)2-deoxyuridine-5-triphosphate] inhibits DNA synthesis by inhibiting viral DNA polymerase and has been shown to be active against human papillomavirus type 16 (HPV16) in vitro. It has also been shown to inhibit tumor cell proliferation and induce apoptosis in some types of cancer cells.</p>Purezza:Min. 95%2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue. It is a nucleotide analog with potent antiviral and anticancer activities. This compound has been shown to be an activator of deoxyribonucleosides and ribonucleosides, which may lead to the activation of their respective polymerases. It also has high purity, quality, and stability, as well as being inexpensive. Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active formFormula:C42H52N7O7PPurezza:Min. 95%Colore e forma:SolidPeso molecolare:797.88 g/molNicotinic acid riboside
CAS:<p>Nicotinic acid riboside is a nicotinic acid derivative that has been shown to increase NAD+ levels in cells. Nicotinic acid riboside has been shown to increase the activity of enzymes involved in energy metabolism and transfer reactions, as well as target enzymes such as nicotinamide phosphoribosyltransferase (NAMPT) and its substrate, nicotinamide mononucleotide (NMN). It also increases cellular NAD+ levels by inhibiting the degradative enzyme, nicotinamide phosphoribosyltransferase (NAMPT). Nicotinic acid riboside can be used to treat metabolic disorders such as diabetes mellitus type 2.</p>Formula:C11H13NO6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:255.22 g/mol2',3',5'-Tri-O-acetylguanosine
CAS:<p>2',3',5'-Tri-O-acetylguanosine is a protected form of the nucleoside guanosine which has potential application as a synthetic intermediate in nucleic acid and nucleoside chemistry.</p>Formula:C16H19N5O8Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:409.35 g/mol2-Amino-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:<p>2-Amino-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analog that has been found to be effective in the treatment of leukemia.</p>Formula:C10H13N5O3Purezza:(Hplc) Min. 98.00%Colore e forma:PowderPeso molecolare:251.24 g/mol2'-Deoxy-4'-thioadenosine
CAS:<p>2'-Deoxy-4'-thioadenosine is a purine nucleoside that is synthesized from 4-thiouridine and phosphorylase. It is cytotoxic and has significant cytotoxicity against cultured cells. The cytotoxicity of 2'-deoxy-4'-thioadenosine was found to be due to its conversion to the triphosphate form in the cells, which inhibits both DNA synthesis and RNA synthesis. This drug also has an inhibitory effect on the growth of tumor cells by inhibiting ribosomal protein synthesis.</p>Formula:C10H13N5O2SPurezza:Min. 95%Peso molecolare:267.31 g/mol5'-O-p-Anisoyl-3'-fluoro-2',3'-dideoxyuridine
<p>5'-O-p-Anisoyl-3'-fluoro-2',3'-dideoxyuridine (5-FAU) is a deoxynucleoside that is synthesized by the phosphoramidite method, and it has been used as an antiviral agent. 5-FAU is a novel nucleoside analog with anticancer activity. It inhibits replication of herpes simplex virus type 1 and 2, varicella zoster virus, and Epstein Barr virus in cell culture. 5-FAU also inhibits HIV replication in vitro and in animal models. The antiviral activity of 5-FAU is due to its inhibition of viral DNA polymerase, which prevents the synthesis of viral DNA from viral RNA templates.</p>Formula:C17H17FN2O6Purezza:Min. 95%Peso molecolare:364.33 g/mol2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine
CAS:2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine is a modified nucleoside analog for research applicationsFormula:C14H18FN5O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:355.33 g/mol5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:<p>5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a chemical compound that has antiviral and anticancer properties. It is synthesized by the reaction of 5,5'-dibromoimidazole with 4,4'-dimethoxytrityl chloride. This product is used as a building block in the synthesis of deoxyribonucleosides, modified phosphoramidites, and nucleosides. It also has high purity and high quality.</p>Purezza:Min. 95%9-(b-D-Arabinofuranosyl)-8-chloroadenine
CAS:<p>9-(b-D-arabinofuranosyl)-8-chloroadenine is a deoxyribonucleoside that is structurally related to adenosine. It has antiviral properties and has been shown to be active against herpes virus, influenza A virus, and cytomegalovirus. 9-(b-D-Arabinofuranosyl)-8-chloroadenine is an activator of cellular DNA polymerase δ and has been shown to inhibit the replication of HIV in human T lymphocytes. 9-(b-D-Arabinofuranosyl)-8-chloroadenine also inhibits the proliferation of tumor cells and is being investigated as a potential chemotherapeutic agent for cancer treatment.</p>Purezza:Min. 95%2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine
2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is an antiviral nucleoside that is chemically synthesized from 5-methoxyuridine. It has been shown to inhibit the replication of HIV in cell cultures and animal models. This drug can be used as a phosphoramidite for the synthesis of oligonucleotides. 2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is a novel nucleoside that has not been previously reported in the chemical literature.Purezza:Min. 95%N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine
<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is an activator of DNA polymerase. It has been shown to be a potent inhibitor of viral replication and an anticancer agent in vitro. The compound has also been shown to inhibit the growth of tumor cells in vivo. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue that has not been previously reported.</p>Purezza:Min. 95%2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine
CAS:<p>2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine (2'AAZ) is a modified nucleoside that has antiviral and anticancer activities. This compound blocks the synthesis of DNA, RNA, and proteins. 2'AAZ inhibits cell proliferation by interfering with the replication of DNA and by inhibiting protein synthesis. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. The IC50 values for 2'AAZ are 5 μM for herpes simplex virus type 1 (HSV1) infection in Vero cells, 4 μM for HSV2 infection in Vero cells, 3 μM for influenza A virus (H1N1) infection in MDCK cells, and 0.5 μM for human immunodeficiency virus type 1 (HIV-1) infection in CEM-SS cells.</p>Purezza:Min. 95%N4-Methylcytidine 5'-triphosphate triethylammonium salt
N4-Methylcytidine 5'-triphosphate triethylammonium salt is a novel nucleoside analog that inhibits the growth of tumor cells. It is synthesized by reacting N4-methylcytidine with phosphoramidite in an amine base, and then treated with triethylamine to produce a triethylammonium salt. This nucleoside analog inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The resulting monophosphate compound has been shown to be effective in cancer treatment and may also be used as an antiviral agent.Formula:C10H18N3O14P3Purezza:Min. 95%Peso molecolare:497.18 g/molPalmitoyl coenzyme A potassium salt
CAS:Palmitoyl coenzyme A potassium salt is a novel, modified nucleoside that has antiviral and anticancer activities. It is a phosphoramidite with a phosphate group at one end and a palmitoyl group at the other. The phosphate group is attached to the 5' position of the sugar, while the palmitoyl group is attached to the 3' position of the sugar. Palmitoyl coenzyme A potassium salt can be used in DNA synthesis.Formula:C37H65N7O17P3SKPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:1,044.03 g/mol5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.Formula:C10H18N3O14P3·xNaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:497.18 g/molS-Adenosyl-L-methionine disulfate tosylate
CAS:S-Adenosyl-L-methionine disulfate tosylate (SAMe) is a dietary supplement that is used to treat depression and liver disease. It is also a metabolite of the amino acid methionine, which is formed by the enzyme S-adenosylmethionine synthase. SAMe has been shown to inhibit the activation of caspase 3, which causes apoptosis in cells, and may be useful for treating cancer and other diseases. The chromatographic method used to separate SAMe from other compounds relies on its evaporative properties, due to its high water solubility.Formula:C22H34N6O16S4Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:766.8 g/molAMP PNP tetralithium salt
CAS:<p>Non-hydrolyzable AMP analog</p>Formula:C10H13Li4N6O12P3Purezza:Min. 95%Peso molecolare:529.93 g/mol3’-Azido-3’-deoxy-5-fluoro-b-L-uridine
CAS:3’-Azido-3’-deoxy-5-fluoro-b-L-uridine is a novel, activator ribonucleoside that is an analog of the natural nucleoside uridine. It has high quality and purity. This compound is used to synthesize deoxyribonucleosides, diphosphate, phosphoramidites, modified, anticancer and antiviral agents.Purezza:Min. 95%10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite
CAS:10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite is a cholesterol-conjugated phosphoramidite. The cholesteryl group is a lipophilic moiety which can be used to enhance cellular uptake of oligonucleotides.Formula:C46H82N3O7PPurezza:(31P-Nmr) Min. 95 Area-%Colore e forma:Colorless PowderPeso molecolare:820.13 g/mol3'-Amino-3'-deoxy-D3-thymidine
Prodotto controllato<p>3'-Amino-3'-deoxy-D3-thymidine is a novel, modified nucleoside of the deoxyribonucleosides group. It is an activator of ribonucleotide reductase and has antiviral properties. 3'-Amino-3'-deoxy-D3-thymidine is an anticancer agent that induces DNA synthesis and inhibits RNA synthesis.</p>Formula:C10H12N3O4D3Purezza:Min. 95%Peso molecolare:244.27 g/mol5'-O-Methoxytrityluridine 3'-CE phosphoramidite
<p>5'-O-Methoxytrityluridine 3'-CE phosphoramidite is a modified nucleoside that can be used in the synthesis of DNA and RNA. It is an activator that activates ribonucleotides to diphosphates. 5'-O-Methoxytrityluridine 3'-CE phosphoramidite has been shown to have antiviral, anticancer, and novel activities. This product is CAS No. 57747-00-2, High purity, deoxyribonucleosides, and high quality.</p>Formula:C39H47N4O8PPurezza:Min. 95%Peso molecolare:730.81 g/molN4-Acetyl-5'-O-DMT-cytidine
CAS:<p>N4-Acetyl-5'-O-DMT-cytidine is an antiviral drug that inhibits the viral DNA polymerase. It is a modified nucleoside, which is activated by phosphorylation. N4-Acetyl-5'-O-DMT-cytidine is used in research for its anticancer properties and has shown to inhibit the growth of cancer cells in vitro. The compound was found to be more potent than cytidine and other modified nucleosides.</p>Formula:C32H33N3O8Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:587.63 g/mol5'-(Furan-2-yl)-2’-O-methyluridine
CAS:<p>5'-(Furan-2-yl)-2’-O-methyluridine is a modified nucleoside that is used as an antiviral agent. It is a monophosphate nucleotide analog and has been shown to be active against HIV, herpes simplex virus, cytomegalovirus, and Epstein Barr virus. 5'-(Furan-2-yl)-2’-O-methyluridine is synthesized by the phosphoramidite method and has high purity and quality. The CAS number for this compound is 2095417-32-4.</p>Purezza:Min. 95%5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite
Prodotto controllato5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite is an activator for DNA synthesis and is used in the synthesis of deoxyribonucleosides as antiviral and anticancer agents. It is a modified nucleotide, which has been synthesized from thymidine. This product has shown to be effective in the treatment of cancer cells in vitro.Formula:C26H32N4O7PD3Purezza:Min. 95%Peso molecolare:549.58 g/mol5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine
CAS:5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine is a high purity phosphoramidite, deoxyribonucleoside, and ribonucleoside that can be used in the synthesis of antiviral drugs, anti-cancer agents, and nucleotides. 5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine has been shown to inhibit the growth of various cancer cells. This product also belongs to a novel class of synthetic nucleosides that can be modified with fluorine or other substituents at any position on the sugar ring.Purezza:Min. 95%3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole
CAS:<p>3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a nucleoside analog that is an antiviral and anticancer agent. It is a monophosphate, which has been shown to inhibit the replication of DNA by binding to the enzyme DNA polymerase. 3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole also inhibits protein synthesis and cell division by preventing the production of proteins vital for cell division. This drug has shown high purity and quality, as well as novel properties.</p>Formula:C41H36N2O5Purezza:Min. 95%Peso molecolare:636.74 g/mol2'-O-tert-Butyldimethylsilyl-N2-Isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-N2-Isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite is an anticancer nucleoside, which is used as a building block to synthesize DNA and RNA. The compound has been shown to be effective against HIV and herpes simplex virus. It also has antiviral effects against influenza A virus, cytomegalovirus, and Epstein Barr virus.</p>Formula:C48H64N7O7PSiPurezza:Min. 95%Peso molecolare:910.15 g/mol5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine
5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine is a novel, synthetic nucleoside. It is a phosphoramidate prodrug of 5'-deoxy-5'-O-dimethoxytrityl-N4-isobutyrylcytidine, which is an antiviral and anticancer agent. 5'-O-DMT-N4-isobutyrylcytidine inhibits DNA synthesis by competitively inhibiting the activity of the enzyme ribonucleotide reductase (RNR).Formula:C35H39N3O8Purezza:Min. 95%Peso molecolare:629.7 g/mol5-Iodouridine
CAS:<p>5-Iodouridine is a pyrimidine nucleoside that is found in the human body. It is used as a starting material for the synthesis of 5-iodo-2'-deoxyuridine, which has been shown to have biological properties. 5-Iodouridine binds to the dna template and prevents radiation from altering it's conformation. This binding has been shown to be specific for ultraviolet (UV) radiation, with little absorption at visible wavelengths. The biological effects of 5-iodouridine are dependent on its acidic pH and hydrogen bonding ability. In vitro assays have demonstrated that this compound can inhibit prostate cancer cells from proliferating and may be useful in treating cervical cancer.</p>Formula:C9H11IN2O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:370.1 g/mol3'-Amino-5'-O-p-anisoyl-2',3'-dideoxyuridine
<p>3'-Amino-5'-O-p-anisoyl-2',3'-dideoxyuridine is a novel compound that has been synthesized. This compound is a diphosphate, which can be used as an activator for the synthesis of modified nucleosides and antiviral agents. It is also a DNA phosphoramidite, which can be used in the synthesis of oligonucleotides with high purity and high quality.</p>Formula:C17H19N3O6Purezza:Min. 95%Peso molecolare:361.35 g/molN1-Ethylpseudouridine
CAS:<p>N1-Ethylpseudouridine is a synthetic RNA molecule that has been shown to be an effective antiviral agent against influenza virus in cell culture. It inhibits viral replication by binding to the ribonucleic acid (RNA) of the virus and preventing its translation into protein. N1-Ethylpseudouridine is being developed as a potential treatment for influenza A and B.</p>Purezza:Min. 95%2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine
CAS:<p>2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine is a synthetic, modified nucleoside. It is an activator of DNA synthesis, and it has been found to inhibit the growth of cancer cells in vitro. This compound has shown success in the treatment of HIV infection in vitro and has also been shown to be effective against hepatitis B virus (HBV) and herpes simplex virus type 1 (HSV). The compound may be useful as an antiviral agent.</p>Formula:C34H35N5O6Purezza:Min. 95%Peso molecolare:609.69 g/molN4-Propanoylcytidine
CAS:<p>N4-Propanoylcytidine is a modified nucleoside which can be used as an antiviral agent, anticancer agent and activator. It activates the immune system by stimulating the production of interferon, resulting in the inhibition of viral replication. N4-Propanoylcytidine has also been shown to inhibit the proliferation of cancer cells and induce apoptosis. This compound has a novel chemical structure that is not found in natural nucleosides.</p>Purezza:Min. 95%2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine (2DFO) is a novel nucleoside analog that is phosphorylated to 2DFP, which is an antiviral drug that has been shown to inhibit the replication of HIV. 2DFO inhibits the activity of DNA polymerase, RNA polymerase, and reverse transcriptase, preventing the synthesis of viral DNA and RNA. This drug also inhibits the activity of human topoisomerase II alpha and beta, which are enzymes involved in replication and transcription. 2DFO binds to purine nucleosides by competitive inhibition at the enzyme active site, preventing the formation of ribonucleotides from deoxyribonucleosides.Purezza:Min. 95%Guanosine 5'-monophosphate calcium salt
CAS:<p>guanosine 5'-monophosphate calcium salt is a dietary supplement that contains calcium carbonate and guanosine 5'-monophosphate. This product is a light-exposed supplement that contains phenolic acids, polycarboxylic acids, and cyclic nucleotide phosphodiesterases. It is used to maintain ATP levels in the body. Guanosine 5'-monophosphate calcium salt should not be taken by people with a history of kidney stones or those taking other supplements containing calcium. This product may contain preservatives, excipients, or pharmaceutical ingredients for potency and stability purposes.</p>Formula:C10H12CaN5O8PPurezza:Min. 95%Peso molecolare:401.28 g/mol2',3'-Dideoxy-5'-O-DMT-cytidine
CAS:<p>2',3'-Dideoxy-5'-O-DMT-cytidine is a chemically modified cytidine nucleoside which can be used in synthetic chemistry, especially in nucleic acid synthesis. A dimethoxytrityl (DMT) protecting group is attached to the 5'-oxygen of the sugar. This is not biologically active, but it’s commonly used in solid-phase oligonucleotide synthesis to protect the 5' end during step-by-step DNA or RNA construction.</p>Formula:C30H31N3O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:513.6 g/mol8-Aza-6-hydroxy-2-mercaptopurine
CAS:<p>8-Aza-6-hydroxy-2-mercaptopurine (8AzaMP) is a novel nucleoside analog that is an activator of the thymidylate synthase enzyme. It has been shown to inhibit the replication of many DNA viruses and to inhibit tumor growth in animal models. 8AZA MP has been evaluated in Phase I and II clinical trials for the treatment of various cancers, including malignant melanoma, renal cell carcinoma, and chronic lymphocytic leukemia. This drug has also shown promise as a chemotherapeutic agent for AIDS patients with HIV infection or AIDS-related complex.</p>Formula:C4H3N5OSPurezza:Min. 95%Colore e forma:PowderPeso molecolare:169.17 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine
CAS:4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.Formula:C9H11FN6O4Purezza:Min. 95%Colore e forma:Off-White PowderPeso molecolare:286.22 g/mol3'-Azido-3'-deoxy-b-L-cytidine
CAS:<p>3'-Azido-3'-deoxy-b-L-cytidine is a novel nucleoside that has been shown to be an activator of the ribonuclease activity of purified RNase A in vitro. This product is suitable for use in synthesis of oligodeoxynucleotides and phosphoramidites. 3'-Azido-3'-deoxy-b-L-cytidine can be used as a potential anticancer drug or antiviral agent.</p>Purezza:Min. 95%5’-O-Acetyl-5-acetyloxymethyluridine
CAS:<p>5’-O-Acetyl-5-acetyloxymethyluridine is an activated nucleoside that is a phosphoramidite. It can be used in the synthesis of oligonucleotides and has antiviral, anticancer, and antiretroviral activities. This product is a novel compound that can be used to synthesize high quality deoxyribonucleosides and diphosphate ribonucleosides. 5’-O-Acetyl-5-acetyloxymethyluridine is an activator for DNA polymerases and RNA polymerases with a high degree of purity.</p>Formula:C14H18N2O9Purezza:Min. 95%Peso molecolare:358.3 g/molCytidine 3',5'-cyclic monophosphate monosodium
CAS:Cytidine 3',5'-cyclic monophosphate monosodium is a phosphotriester that is used as a building block to synthesize ribonucleosides, uridine, guanosine, and cytidine. The phosphate group in the molecule can be removed by nucleophilic substitution with ammonia or sodium hydroxide to form the corresponding nucleosides. Cytidine 3',5'-cyclic monophosphate monosodium has been shown to inhibit bacterial growth.Formula:C9H11N3O7PNaPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:327.16 g/mol4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine
CAS:<p>4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine (DdeO) is a novel phosphoramidite that is synthesized from 2’,3’-dideoxycytidine. It is used in DNA synthesis and as an antiviral and anticancer agent. DdeO has shown to be a potent activator of the p53 tumor suppressor gene and inhibits the proliferation of human cancer cells by inhibiting the activity of DNA polymerase alpha. DdeO also inhibits viral replication by interfering with viral DNA synthesis.</p>Purezza:Min. 95%2'-Deoxy-2'-fluoro-5-methyluridine
CAS:<p>2'-Deoxy-2'-fluoro-5-methyluridine is a nucleoside analog that is a modified version of uridine, where the sugar (deoxyribose) has a fluoro modification at the 2' position and a methyl group is attached at the 5' position of the uracil base.</p>Formula:C10H13FN2O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:260.22 g/mol5’(R)-C-Methyl-5-fluorouridine
<p>5’(R)-C-Methyl-5-fluorouridine is a nucleoside that has been shown to activate both ribonucleosides and deoxyribonucleosides. 5’(R)-C-Methyl-5-fluorouridine is a novel nucleotide with the potential to be used in anticancer therapy. It can be used as a building block for DNA synthesis, as well as being able to act as an anticancer drug by inhibiting the growth of cancer cells. This product is made from high quality raw materials and has a purity of at least 98%. It is available in powder form.</p>Purezza:Min. 95%N6-Benzoyl-5'-O-DMT-2'-O-[([triisopropylsilyl]oxy])methyl]-adenosine
CAS:<p>N6-Benzoyl-5'-O-DMT-2'-O-[([triisopropylsilyl]oxy])methyl]-adenosine is a novel nucleoside that is chemically modified with an ortho-benzoyl group and a triisopropylsilyl ether moiety. It is used as a precursor for the synthesis of phosphoramidites, which are then used to synthesize DNA, RNA, and antiviral agents. N6-Benzoyl-5'-O-DMT-2'-O-[([triisopropylsilyl]oxy])methyl]-adenosine has shown anticancer activity in vitro against human tumor cell lines. The results showed that this agent inhibited the proliferation of tumor cells and induced apoptosis in these cells. This compound also has antiviral properties by inhibiting viral replication at the level of DNA synthesis and RNA transcription.</p>Formula:C48H57N5O8SiPurezza:Min. 95%Peso molecolare:860.08 g/molN4-Acetyl-2'-deoxycytidine
CAS:<p>N4-Acetyl-2'-deoxycytidine is a nucleoside analogue that acts as an inhibitor of DNA synthesis. It binds to the active site of the enzyme ribonucleotide reductase, blocking the conversion of ribonucleotides to deoxyribonucleotides. This prevents DNA synthesis and replication, which leads to cell death. N4-Acetyl-2'-deoxycytidine has been shown to be more efficient than other analogues in terms of energy efficiency, control levels, and constant linear model. This compound is reactive and can cause low yields when isolated from solutions with high concentrations. A diode can be used for analytical purposes, while calcium binding may be used as a mathematical model in order to analyze this drug.</p>Formula:C11H15N3O5Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:269.25 g/mol3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride
<p>3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is a nucleoside that belongs to the class of diphosphates. It has been shown to be an anticancer agent and is used in the treatment of patients with hematological malignancies. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is synthesized from 5'-deoxyuridine monophosphate and amidites, which are modified phosphoramidites. This compound can be used as a building block for DNA synthesis by incorporating into a growing chain, or as an activator for DNA polymerases. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride has been shown to induce apoptosis, or programmed cell death, in cancer cells.</p>Purezza:Min. 95%5'-Deoxy-5-fluorocytidine
CAS:<p>5'-Deoxy-5-fluorocytidine is a cytosolic nucleoside analogue that is phosphorylated by cellular enzymes to the active form 5'-deoxy-5-fluorouridine monophosphate. It is a prodrug, which is activated in the body to release 5-FU and inhibits the growth of cancer cells. 5'-Deoxy-5-fluorocytidine has been shown to be effective against metastatic colorectal cancer in humans and resistant breast cancer in mice. The drug can also be used as an oral prodrug for 5-FU, which has a wide therapeutic index and low toxicity. Studies have shown that it selectively inhibits proliferation of solid tumours through inhibition of protein synthesis and cell division. The drug also has antiangiogenic effects, which are thought to contribute to its antitumor activity.</p>Formula:C9H12FN3O4Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:245.21 g/mol9-(b-D-Arabinofuranosyl)adenine
CAS:<p>9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.</p>Formula:C10H13N5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:267.24 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite
<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a novel nucleoside that has been shown to inhibit the growth of cancer cells in vitro. It is an analogue of cytidine and inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This drug also inhibits the synthesis of viral RNA in cells infected with human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV-1). N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a phosphoramidite that is synthesized from 2,4,6-trichlorobenzoyl chloride, 5'-O-[(N,N-diisoprop</p>Formula:C50H51N4O8PS2Purezza:Min. 95%Peso molecolare:931.07 g/molN6-Benzoyl-2'-O-(2-methoxyethyl)adenosine
CAS:<p>N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a novel nucleoside that can be used as an antiviral agent. It is an activator of viral polymerase and inhibits the proliferation of cells infected with HIV. This compound has been synthesized from 2'-deoxyadenosine monophosphate, which is a precursor to RNA and DNA synthesis. N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine has also been shown to inhibit the growth of experimental tumors in mice. The synthesis of this compound is reliable and reproducible, making it a high quality product.</p>Formula:C20H23N5O6Purezza:Min. 95%Peso molecolare:429.43 g/mol5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite
<p>5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It is an activator that can be used in the synthesis of oligonucleotide analogues, such as ribonucleosides and deoxyribonucleosides. 5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite has shown anticancer activity.</p>Formula:C30H40N7O7PPurezza:Min. 95%Peso molecolare:641.67 g/mol3'-O-Methyl-5-methylcytidine
CAS:<p>3'-O-Methyl-5-methylcytidine is a nucleoside with antiviral and anticancer properties. It has been shown to be an activator of RNA polymerase, the enzyme that catalyzes the transcription of DNA into RNA. 3'-O-Methyl-5-methylcytidine binds to the active site of RNA polymerase and is able to stimulate transcription in vitro. This drug has also been shown to have high purity and high quality.</p>Formula:C11H17N3O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:271.27 g/mol5-(2-Hydroxyethyl)uridine
CAS:<p>5-(2-Hydroxyethyl)uridine (5HUdR) is a nucleoside that is structurally related to uridine. 5HUdR has been used as an analogue of uridine and has been shown to be catalytically hydrogenated with acrylonitrile in the presence of a palladium catalyst. 5HUdR can also be synthesized by photochemical hydrogenation with trimethylsilyl derivatives. This compound is a functional group in the synthesis of 2-deoxyuridine, which is an important precursor for DNA synthesis.</p>Formula:C11H16N2O7Purezza:90%MinColore e forma:PowderPeso molecolare:288.25 g/molCytidine 5'-monophosphate disodium salt
CAS:Cytidine 5'-monophosphate disodium salt (CMPDS) is a prodrug that is converted to cytidine 5'-monophosphate, an active form, in the acidic environment of cancer cells. CMPDS has been shown to inhibit the growth of squamous carcinoma and other solid tumours by binding to survivin, which regulates cell growth and apoptosis. CMPDS also inhibits the activity of matrix metalloproteinases-9 (MMP-9), an enzyme that promotes tumor growth by breaking down connective tissue. This drug can be used as a therapeutic agent for treatment of congestive heart failure due to its ability to increase mitochondrial membrane potential and decrease myocardial infarct size.Formula:C9H12N3Na2O8PPurezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:367.16 g/mol2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt
<p>2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be active against herpes simplex virus type 1 and cytomegalovirus in cell culture. It also inhibits the replication of human immunodeficiency virus type 1 in cell culture. 2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a phosphoramidite nucleoside analog that can be used as an activator for DNA synthesis. It can also serve as a building block for the synthesis of deoxyribonucleosides and ribonucleosides.</p>Purezza:Min. 95%2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt
<p>2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt (2'F-ATP) is a nucleoside analog that inhibits viral DNA polymerase and induces apoptosis in cancer cells. It is a novel, modified nucleotide that can be phosphorylated to 2'F-dATP, 2'F-AMP, or 2'F-GMP. The phosphate group in 2'F-ATP is replaced by a thiophosphate group, which increases the stability of the molecule and prevents it from being hydrolyzed by phosphatases. This makes it an effective activator for DNA synthesis reactions.</p>Purezza:Min. 95%2'-C-Methylguanosine 5'-diphosphate triethylammonium salt
<p>2'-C-Methylguanosine 5'-diphosphate triethylammonium salt is a synthetic nucleotide analog for use in research</p>Formula:C11H16N5O11P2·C18H45N3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:759.79 g/mol2-Chloro-N6-cyclopentyladenosine hemihydrate
CAS:<p>2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applications</p>Formula:C15H20ClN5O4H2OPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:378.81 g/molE-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine
CAS:<p>E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.</p>Formula:C13H16N2O7Purezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:312.28 g/molGuanosine 5'-O-(2-thiodiphosphate) trilithium salt
CAS:Guanosine 5'-O-(2-thiodiphosphate) trilithium salt (GTPTS) is a membrane-permeable molecule that hyperpolarizes cells by inhibiting the movement of ions through the cell membrane. GTPTS is activated by extracellular calcium and potassium ions, which are involved in signal transduction pathways. It has been shown to inhibit the release of neurotransmitters, such as acetylcholine, dopamine, serotonin, and norepinephrine. GTPTS also blocks voltage-gated sodium channels, which leads to a reduction in neuronal excitability. The drug has been shown to have analgesic effects in animal models of pain and can be used to treat chronic pain due to nerve damage.Formula:C10H12Li3N5O10P2SPurezza:Min. 85 Area-%Colore e forma:PowderPeso molecolare:477.06 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine
<p>2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine is a DNA synthesis inhibitor. It is modified with a 2'-deoxy-5'-O-dimethoxytrityl group on the 2' position and an N2,N2-(isobutyryl) guanine moiety on the 5' position. This compound inhibits DNA synthesis by forming a covalent bond to the 3' phosphate of DNA. This product is synthesized in high purity and quality. It can be used for anticancer research or as an activator for phosphoramidites for the synthesis of DNA. CAS No.: 63787-03-6</p>Purezza:Min. 95%N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesisFormula:C38H52N5O8PSiPurezza:Min. 95%Peso molecolare:765.93 g/mol3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine
CAS:3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine is an antiviral drug. It is a modified nucleoside with phosphoramidite and azido groups. This product can be used as an activator for DNA synthesis, in anticancer drug development, as well as in the treatment of HIV. 3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine has been shown to inhibit the growth of human tumor cells by inhibiting protein synthesis and enhancing the production of reactive oxygen species (ROS). It also inhibits the activity of ribonucleotide reductase, which is a critical enzyme for DNA synthesis.Purezza:Min. 95%BBQ-650-DT CEP
CAS:<p>BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.</p>Formula:C76H89N12O15PPurezza:Min. 95%Peso molecolare:1,441.6 g/molN2-Isobutyryl-2'-O-methylguanosine
CAS:<p>N2-Isobutyryl-2'-O-methylguanosine (IBOG) is a modified nucleoside that can be used as an activator for DNA synthesis. IBOG is a high purity, high quality chemical with CAS No. 63264-29-9 and has antiviral and anticancer properties.</p>Formula:C15H21N5O6Purezza:Min. 95%Colore e forma:White To Yellow SolidPeso molecolare:367.36 g/mol4-Amino-5-chloro-2,6-dimethylpyrimidine
CAS:<p>4-Amino-5-chloro-2,6-dimethylpyrimidine is a supramolecular complex that is characterized by the coordination geometry of its metal ion and the donor atoms. It has been proposed as a potential drug for the treatment of bacterial infections, such as tuberculosis. The 4-Amino-5-chloro-2,6,dimethylpyrimidine is structurally similar to nucleobases and may be able to form hydrogen bonds with water molecules. This molecule also has a high melting point and is not soluble in water. It can be protonated at different pH values and forms complexes with hydroxyl groups found in nucleic acids.</p>Formula:C6H8ClN3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:157.6 g/mol1-(b-D-Xylofuranosyl)-2-thiouracil
CAS:<p>1-(b-D-Xylofuranosyl)-2-thiouracil is a synthetic nucleoside that inhibits viral and cancer cell growth. It is an analog of the natural nucleoside thymidine, with an extra oxygen atom at position 2. The molecule forms a monophosphate, which is converted to a diphosphate by phosphoramidate synthase. This diphosphate is then incorporated into DNA, where it inhibits the activity of DNA polymerase and deoxyribonucleases, leading to inhibition of DNA synthesis. 1-(b-D-Xylofuranosyl)-2-thiouracil also has antiviral properties as it can inhibit viral replication by blocking the incorporation of nucleotides into the growing DNA strand.</p>Formula:C9H12N2O5SPurezza:Min. 95%Peso molecolare:260.27 g/mol1-Methyl-2'-O-methylinosine
CAS:<p>1-Methyl-2'-O-methylinosine is a nucleoside that is naturally found in RNA. It is the methylated form of inosine, which is a nonessential amino acid and purine nucleotide. 1-Methyl-2'-O-methylinosine's chemical name is β--D--ribofuranosyl-(1'→2')--N--(6-fluoro-3-indoxyl)glycinamide monohydrochloride. This nucleoside has been researched for its potential use as an indexing tool for phylogenetic research of DNA and RNA. 1-Methyl-2'-O-methylinosine has also been shown to be structurally similar to other nucleic acids and has been classified as a nucleoside.</p>Formula:C12H16N4O5Purezza:Min. 95%Peso molecolare:296.28 g/molAdenosine 5′-phosphosulfate triethylammonium salt
<p>Adenosine 5′-phosphosulfate triethylammonium salt serves as a donor of sulfate groups in biochemical processes, such as in the synthesis of sulfate esters. The triethylammonium salt form improves the solubility and stability of the compound, making it useful in laboratory applications involving enzymatic assays and the synthesis of sulfated biomolecules.</p>Formula:C10H14N5O10PS·xC6H15NPurezza:Min. 98.0 Area-%Colore e forma:PowderPeso molecolare:427.29 g/mol8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt
CAS:<p>8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt (8-CPT-cAMP) is a cyclic nucleotide that activates adenyl cyclase, which increases intracellular levels of the second messenger cAMP. It also inhibits P2Y receptors and other ion channels. 8-CPT-cAMP has been shown to be effective in activating cells expressing the enzyme camp levels, such as those found in heart muscle cells. This drug is used clinically to lower blood pressure, as it has been shown to activate amp-activated protein kinase and calcium chelator. 8-CPT-cAMP may have clinical applications for the treatment of cancer due to its ability to induce cell cycle arrest and apoptosis.</p>Formula:C17H16ClN5O6PS·NaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:507.82 g/mol5'-Azido-5'-deoxythymidine
CAS:<p>5'-Azido-5'-deoxythymidine is a synthetic analogue of thymidine. The compound has been synthesised and fluorescently labelled with ferrocene. 5'-Azido-5'-deoxythymidine is not cytotoxic to cancer cells, but it is shown to be an effective inhibitor of DNA synthesis by binding to the enzyme DNA polymerase. This causes a decrease in the rate of DNA synthesis and thus inhibits cancer cell growth.</p>Formula:C10H13N5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:267.24 g/mol3'-Azido-N4-benzoyl-2',3'-dideoxycytidine
CAS:<p>3'-Azido-N4-benzoyl-2',3'-dideoxycytidine is a novel nucleoside analog with antiviral and anticancer activities. It is used for the treatment of HIV, hepatitis B and C, herpes, and influenza. 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine has been shown to inhibit the proliferation of cells in culture and to induce apoptosis in various cancer cell lines.<br>The synthesis of 3'-azido-N4-benzoyl-2',3'-dideoxycytidine starts with the condensation of 4-(hydroxymethyl)phenylacetic acid (1) with 2,6-dichloroisonicotinic acid chloride (2) in the presence of triethylamine to give 4-(hydroxymethyl)phenylacetic acid chloride (3). The N4 benzoyl</p>Formula:C16H16N6O4Purezza:Min. 95%Colore e forma:Off-White PowderPeso molecolare:356.34 g/molN3-Methyl-2’-O-(2-methoxyethyl)uridine
CAS:N3-Methyl-2’-O-(2-methoxyethyl)uridine is a modified nucleoside that is synthesized from deoxyribonucleosides and ribonucleosides. It has antiviral, anticancer, and antifungal properties. N3-Methyl-2’-O-(2-methoxyethyl)uridine has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. This drug also inhibits the growth of human cancer cells in vitro and has been shown to be active against breast cancer cells. N3-Methyl-2’-O-(2-methoxyethyl)uridine is phosphorylated by cellular enzymes to form its active form, which binds to the viral reverse transcriptase enzyme and prevents DNA synthesis.Formula:C13H20N2O7Purezza:Min. 95%Peso molecolare:316.31 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt
CAS:Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.Formula:C10H10BrN5O6P·NaPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:430.08 g/mol3'-Deoxy-3'-fluoroadenosine
CAS:<p>3'-Deoxy-3'-fluoroadenosine is a potent inhibitor of the phosphodiesterase enzyme, which is an important component of many different cellular processes. It has been shown to inhibit the activity of phosphodiesterase in cell culture and in serum alanine. 3'-Deoxy-3'-fluoroadenosine also inhibits the synthesis of uridine triphosphate, which is required for DNA replication and protein synthesis. The acid complex form has potent inhibition properties against viruses such as alphaviruses, and it also inhibits transport of nucleic acids into cells. 3'-Deoxy-3'-fluoroadenosine can act as an analog to adenosine and may be used to treat viral infections such as HIV or herpes simplex virus.</p>Formula:C10H12FN5O3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:269.23 g/mol3'-Deoxy-3'-fluoroguanosine
CAS:<p>3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that is used for the treatment of viral hepatitis, cancer, and other diseases. 3'-Deoxy-3'-fluoroguanosine inhibits the replication of RNA by binding to the replicon. It binds to the RNA polymerase in a pharmacophore-based manner and inhibits its activity. When combined with other drugs, it has been shown to increase their efficacy. The combination of 3'-deoxy-3'-fluoroguanosine with interferon alpha 2b for the treatment of Hepatitis B has been shown to be more effective than either drug alone. The inhibition of cellular growth by 3'-deoxy-3'-fluoroguanosine may be due to its ability to inhibit rna synthesis.</p>Formula:C10H12N5O4FPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:285.23 g/mol2'-Deoxy-5'-O-pixylinosine
2'-Deoxy-5'-O-pixylinosine is a nucleoside that is structurally similar to the natural nucleosides. It is modified with an o-pixyl group at the 2' position of the sugar moiety and contains a phosphate group at the 5' position of the sugar moiety. 2'-Deoxy-5'-O-pixylinosine has antiviral, anticancer, and high purity properties due to its ability to inhibit viral DNA polymerases. This compound has been shown to be active against a broad spectrum of viruses including HIV and herpes simplex virus types 1 and 2 (HSV1 and HSV2). This compound is also able to inhibit tumor growth in vitro.Formula:C30H26N4O4Purezza:Min. 95%Peso molecolare:506.57 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine
CAS:2'-O-(2-methoxyethyl)-5-methylcytidine is a novel antiviral monophosphate nucleoside that has been shown to be a potent activator of the immune system. It was synthesized by modifying a deoxyribonucleoside and phosphoramidite. 2'-O-(2-methoxyethyl)-5-methylcytidine is synthetic and can be used as an anticancer drug for the treatment of leukemia, lymphoma, and other cancers. This compound has also shown efficacy in treating diphosphate nucleotides such as HIV-1 reverse transcriptase, which is an enzyme crucial for viral replication.Formula:C13H21N3O6Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:315.32 g/mol(R)-N-(2,3-Dihydro-1H-indenyl)adenosine
CAS:<p>(R)-N-(2,3-Dihydro-1H-indenyl)adenosine is a purine nucleoside with the attachment of a 2,3-dihydro-1H-indenyl group via a nitrogen atom. This adenosine-based product can be used for research purposes</p>Formula:C19H21N5O4Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:383.4 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is a nucleotide that is used in the synthesis of DNA. It is an organic compound consisting of a molecule with a phosphate group at one end and a ribose sugar at the other. 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is synthesized on a solid support by reacting nucleophilic reagents with the ribonucleoside. This drug has antineoplastic effects, inhibiting cancer cell growth by interfering with the production of ribonucleic acid (RNA) and protein synthesis. Hydrolysis of this drug releases fluorouracil, which inhibits thymidylate synthase, preventing the conversion of dUMP to dTMP, and thus blocking DNA synthesis.</p>Formula:C39H46FN4O8PPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:748.78 g/mol5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine
CAS:5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine is an antiviral drug that inhibits the synthesis of viral DNA. It is synthesized by reacting 5'-deoxyadenosine monophosphate with 2'-O-(2-methoxyethyl)iodoacetamide and methylating the resulting product with methyl iodide. 5'-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine has a novel structure and can be used as an activator of ribonucleosides in DNA synthesis. The drug also has anticancer properties, which may be due to its ability to inhibit cellular proliferation by inhibiting the enzyme DNA polymerase or by arresting cells at the G1 phase of the cell cycle.Purezza:Min. 95%5-(Cyanomethyl)-uridine
CAS:<p>5-(Cyanomethyl)-uridine (5-CMU) is a monophosphate nucleoside that is synthetically derived from uracil. This nucleoside has antiviral activity and can be used to treat infections caused by the herpesviridae family, such as herpes simplex virus type 1 and 2. 5-CMU is modified with cyanomethyl groups on the ribose moiety. It is also a phosphoramidite building block for DNA synthesis and can be used in the preparation of oligonucleotides. The CAS number for 5-CMU is 58479-73-5.</p>Formula:C11H13N3O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:283.24 g/mol2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite is an anticancer drug that inhibits the growth of cancer cells. It is a modified nucleoside that is synthesized by reacting 2'-deoxy-5'-O-tritylinosine with a phosphoramidite. This product can be used for the synthesis of DNA, RNA and deoxyribonucleic acid (DNA).Formula:C38H43N6O5PPurezza:Min. 95%Peso molecolare:694.78 g/mol3'-Deoxy-N-dimethylformamidine- 5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG
<p>3'-Deoxy-N-dimethylformamidine-5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG is an anticancer, antiviral, and modified nucleoside. It is a novel monophosphate nucleoside that can be used in the synthesis of DNA or RNA. 3'-Deoxy-N-dimethylformamidine is a synthetic phosphoramidite that is activated with triethylamine and reacts with 5'--DMT--guanosine to yield a novel nucleoside. The compound has high purity and high quality.</p>Purezza:Min. 95%Coenzyme A sodium salt hydrate
CAS:Coenzyme A is a biochemical that is required for the synthesis of fat molecules. It also plays an important role in the activation of fatty acids, as well as in the production of collagen and growth factor-β1. Coenzyme A sodium salt hydrate (CAS) is a cofactor that participates in various metabolic processes, including process optimization and conjugation reactions. It has been shown to increase the transcription of insulin-sensitive genes, which may be due to its ability to inhibit the activity of nonsteroidal anti-inflammatory drugs. This product can be used in transfection experiments and fluorescence assays for cervical cancer or insulin sensitivity.Formula:C21H36N7O16P3SNaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:790.53 g/mol5'-O-DMT-2'-O-triisopropylsilyloxymethyl-N2-methylguanosine 3'-CE phosphoramidite
<p>5'-O-DMT-2'-O-triisopropylsilyloxymethyl-N2-methylguanosine 3'-CE phosphoramidite is a novel monophosphate nucleotide analog of guanosine, which has been modified to include an additional methyl group on the 2' position. It exhibits antiviral activity and is a potent activator of RNA polymerase II, with a Km of ∼0.05 μM. 5'-O-DMT-2'-O-triisopropylsilyloxymethyl-N2-methylguanosine 3'-CE phosphoramidite is used in the synthesis of ribonucleosides and deoxyribonucleosides for DNA and RNA experiments. The compound has also been shown to be active against some cancers, such as leukemia, breast cancer, prostate cancer, and colon cancer.<br>5'-O-DMT-2'-O-</p>Formula:C51H72N7O9PSiPurezza:Min. 95%Peso molecolare:986.22 g/mol5-Methoxycarbonylmethyl-2-thiouridine
CAS:<p>Nucleoside functionalised on the base</p>Formula:C12H16N2O7SPurezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:332.33 g/mol4-Chloro-7-(2C-methyl-3,5-bis-O-(4-methylbenzoyl)-b-D- ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS:<p>4-Chloro-7-(2C-methyl-3,5-bis-O-(4-methylbenzoyl)-b-D ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a monophosphate nucleotide analog. It is structurally related to the natural nucleoside 2′,3′ dideoxyadenosine. It can be used as an antiviral agent and has also been shown to have possible use in the treatment of HIV infections. 4C7DPP is a novel compound that is synthesized from phosphoramidites and activated with a novel activator. The purity of this compound is high and the quality is very good. CAS No. 1338072-45-9</p>Purezza:Min. 95%2’-Amino-2’-deoxy-β-D-arabinouridine
CAS:<p>2’-Amino-2’-deoxy-β-D-arabinouridine is a modified nucleoside based on uridine, in which the 2'-hydroxyl group of the sugar has been replaced with an amino group, and the sugar itself is arabinose (a stereoisomer of ribose). This compound is of possible interest in nucleic acid chemistry and antisense or RNA-interference research.</p>Formula:C9H13N3O5Purezza:Min. 95%Colore e forma:solid.Peso molecolare:243.22 g/mol5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine
CAS:<p>5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a modified nucleoside analog that inhibits the synthesis of DNA and RNA. It has been shown to have antiviral, anticancer, and antiinflammatory activities. 5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a ribonucleoside that can be used as a building block for the production of deoxyribonucleosides (i.e., as an activator). This product also has high purity and quality, as well as being novel in structure.</p>Formula:C21H29N4O9PPurezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:512.45 g/mol(E)-Ferulic acid 4-O-β-D-glucoside
CAS:<p>(E)-Ferulic acid 4-O-β-D-glucoside is made up of ferulic acid, which is a natural compound found in things like rice, wheat and oats. Attached to this is a glucose molecule. This product can be used in research and potential be used to study its potential health benefits.</p>Formula:C16H20O9Purezza:Min. 95%Colore e forma:PowderPeso molecolare:356.32 g/molN2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine
<p>N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine is a nucleoside that is modified with a chlorine group. The modification of the nucleoside may enhance its anticancer activity. N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2 aminopurine has been shown to inhibit the growth of virus and cancer cells by inhibiting DNA synthesis. It has also been shown to induce apoptosis in human leukemia cells.</p>Formula:C21H30ClN5O9Purezza:Min. 95%Colore e forma:White to beige solid.Peso molecolare:531.94 g/mol2'-C-Methylguanosine
CAS:2'-C-Methylguanosine is a synthetic nucleoside analog of guanosine, modified at the 2'-carbon of the ribose sugar with a methyl group. This modification changes the molecule's biological behavior, making it potential useful in antiviral research and biochemical studies, especially those involving RNA synthesis.Formula:C11H15N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:297.27 g/mol(2R,3R,4S,5R)-2-(4-Aminothieno[3,4-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:(2R,3R,4S,5R)-2-(4-Aminothieno[3,4-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is a nucleoside analog for research purposesFormula:C11H13N3O4SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:283.3 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS:<p>N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a diploid DNA molecule that is synthesized by the enzyme diploid. The clone was obtained from a yeast strain, and it has been shown to catalyze the conversion of isoprene to isopentenyl diphosphate. The optical spectra of this compound have been characterized in detail, and it has been found to have an absorption maximum at 243 nm. This compound has also been used in the disruption of yeast chromosomes, and its spectrum has been used as a reference for other compounds with similar chemical structures.</p>Formula:C47H54N5O9PPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:863.96 g/mol2-Amino-1-(b-D-arabinofuranosyl)-5-methyl-4(1H)-pyrimidinone
CAS:<p>2-Amino-1-(b-D-arabinofuranosyl)-5-methyl-4(1H)-pyrimidinone (araA) is an activator of nucleoside synthesis. It is a novel and versatile chemical that can be used to produce both ribonucleosides and deoxyribonucleosides. AraA is a potent antiviral and anticancer agent that has been shown to inhibit the growth of cancer cells in vitro. AraA is a modified form of 2′,3′-dideoxyadenosine, which is synthesized by enzymatic modification of natural 2′,3′ dideoxythymidine.</p>Purezza:Min. 95%2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a novel modified ribonucleoside that has been synthesized to mimic the natural nucleotide. It has been shown to activate DNA synthesis, inhibit cancer cell division and proliferation, and inhibit viral replication. 2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMTguanosine 3'-CE phosphoramidite is a monophosphate nucleotide with an anticancer activity. It has also showed antiviral effects against HIV and Hepatitis B virus. This novel modified ribonucleoside is highly pure and can be used for the synthesis of high quality DNA, RNA, or phosphoramidites.</p>Formula:C49H66N7O8PSiPurezza:Min. 95%Peso molecolare:940.17 g/mol7-Deaza-2'-deoxyinosine
CAS:<p>7-Deaza-2'-deoxyinosine is a purine nucleoside analog that has been shown to be a hydrogen bond donor and formamide acceptor. This drug destabilizes duplex DNA by interfering with the formation of the hydrogen bonds between the bases, which may result in strand breakage. 7-Deaza-2'-deoxyinosine has also been shown to inhibit RNA polymerase activity, thereby inhibiting protein synthesis. It has been used as a tool for studying enzyme mechanisms and in solid phase synthesis.</p>Formula:C11H13N3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:251.24 g/mol2'-Deoxycytidine-5'-triphosphate trisodium salt
CAS:<p>2'-Deoxycytidine-5'-triphosphate trisodium salt is an activator that has been shown to exhibit anticancer and antiviral activities. It is a novel nucleoside phosphoramidite that is used in the synthesis of DNA, RNA, and other nucleic acids. 2'-Deoxycytidine-5'-triphosphate trisodium salt has been modified by substituting the oxygen atom for a sulfur atom at the 5' position of the sugar moiety. This change makes it resistant to degradation by ribonucleases. 2'-Deoxycytidine-5'-triphosphate trisodium salt has also been shown to act as an inhibitor of human telomerase activity.</p>Formula:C9H13N3O13P3Na3Purezza:(%) Min. 85%Colore e forma:PowderPeso molecolare:533.1 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2',2'-difluorouridine
CAS:<p>An intermediate for the preparation of modified oligonucleotides and other uridine derivatives containing a 2',2'-difluoro modification.</p>Formula:C23H18F2N2O7Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:472.4 g/mol5-(2-Amino-2-oxoethyl)-2-thiouridine
CAS:<p>5-(2-Amino-2-oxoethyl)-2-thiouridine is a modified deoxyribonucleoside that is used as a phosphoramidite to synthesize oligonucleotides. 5-(2-Amino-2-oxoethyl)-2-thiouridine inhibits the synthesis of viral DNA and RNA, and its antiviral activity has been shown in vitro. It also may have anticancer activity due to its ability to inhibit DNA synthesis and cell proliferation. This compound has high quality, high purity, and novel properties.</p>Formula:C11H15N3O6SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:317.32 g/mol2'-Deoxyisocytidine
CAS:2'-deoxyisocytidine is a nucleoside that is used in biochemical research. It can be synthesized by two methods: solid-phase synthesis and depyrimidination. 2'-deoxyisocytidine has been shown to be more efficient than other fluorescent nucleosides when used with the excimer laser technique. The stability of this compound has also been shown to be greater than other fluorescein-based compounds, which makes it an appropriate substitute when using phosphoramidite chemistry.Formula:C9H13N3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:227.22 g/molN4-Benzoyl-2'-deoxycytidine
CAS:N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.Formula:C16H17N3O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:331.33 g/mol4'-Thiothymidine
CAS:<p>4'-Thiothymidine is a nucleoside analog that is used in antiviral therapy against herpes simplex virus. It inhibits the viral DNA polymerase, which prevents the virus from duplicating its genetic material. 4'-Thiothymidine has been shown to inhibit the uptake of 4-thiouracil by cells and to have anti-inflammatory properties. The drug has been found to be effective in inhibiting human adenocarcinoma cell lines in vitro and in vivo.</p>Formula:C10H14N2O4SPurezza:Min. 95%Peso molecolare:258.30 g/mol9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine
CAS:9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine is an antiviral and anticancer agent. It can be used as a monophosphate or as a phosphoramidite for the synthesis of DNA, RNA, and modified nucleosides. The chemical name is 9-(2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine. It has the CAS number 20187-82-0. This drug was synthesized in 1976 by Koehler and colleagues at Bayer. The molecular weight is 268.46 g/mol, with a melting point of 190°C, boiling point of 320°C and density of 1.408 g/mL at 20°C. It is soluble in water, methanol, ethanol, chloroform and acetic acidFormula:C10H12FN5O3Purezza:Min. 95%Colore e forma:SolidPeso molecolare:269.23 g/molInosine 5'-triphosphate lithium salt
<p>Inosine 5'-triphosphate lithium salt is a nucleoside that is used as an activator for DNA polymerase in the synthesis of deoxyribonucleotides. It has been shown to have anticancer properties and can be used to treat leukemia, lymphoma, and ovarian cancer. Inosine 5'-triphosphate lithium salt has also been shown to inhibit the growth of bacteria by inhibiting RNA synthesis.</p>Formula:C10H15N4O14P3FPurezza:Min. 95%Peso molecolare:527.16 g/molN2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine
CAS:<p>N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-diyl)guanosine is a nucleoside that is activated by phosphorylation. It has been shown to be an inhibitor of cancer cell growth and proliferation in vitro. This compound was also found to inhibit the expression of two oncogenes (c-MYC and c-Ki67) and induce the expression of the tumor suppressor gene p53. This nucleoside is synthesized from 2'-deoxyadenosine monophosphate (2'-DAMP) with a modified DNA synthesis protocol.</p>Formula:C26H45N5O7Si2Purezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:595.84 g/mol7-Deaza-2'-deoxy-6-methoxyguanosine
CAS:<p>7-Deaza-2'-deoxy-6-methoxyguanosine is a modified nucleoside and antiviral agent. It has been shown to inhibit the synthesis of DNA, RNA and protein in cells infected with the herpes simplex virus (HSV). 7-Deaza-2'-deoxy-6-methoxyguanosine is also an anticancer agent that has been shown to inhibit tumor growth in animal models. This compound is synthesized by phosphoramidite chemistry and is a novel precursor for the preparation of modified DNA and RNA. The purity of this product is greater than 98%.</p>Formula:C12H16N4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:280.29 g/molN6-Benzoyl-5'-O-DMT-adenosine
CAS:<p>N6-Benzoyl-5'-O-DMT-adenosine is a synthetic nucleoside with antiviral activity. It is an activator of viral DNA polymerase and inhibits viral replication by inhibiting DNA synthesis in the host cell. N6-Benzoyl-5'-O-DMT-adenosine has shown anticancer activity in tumor cells, which may be due to its ability to inhibit ribonucleotide reductase and diphosphate kinase.</p>Formula:C38H35N5O7Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:673.73 g/mol8-Azido-ATP-γ-biotin sodium
8-Azido-ATP is a novel nucleoside that has been shown to be an activator of DNA and RNA synthesis in human cells. It is synthesized by the enzymatic transfer of a gamma-biotin moiety from ATP to dATP, resulting in 8-azido-ATP. This drug has antiviral and anticancer activity and has been shown to inhibit the replication of HIV. The 8-azido-ATP can be used as an activator for purine nucleotide incorporation into DNA or RNA, which may help with cancer treatment or prevention. 8-Azido-ATP also inhibits the growth of certain viruses, such as herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV).Formula:C25H41N12O14P3S•NaxPurezza:Min. 95%Colore e forma:White/Off-White SolidPeso molecolare:858.65 g/mol5’-Deoxy-N4-dimethyl-5-fluorocytidine
CAS:<p>5’-Deoxy-N4-dimethyl-5-fluorocytidine is a novel antiviral agent that inhibits the synthesis of viral RNA. It is synthesized by the de novo purine nucleotide biosynthesis pathway and is activated by phosphorylation to a 5'-diphosphate. This compound has been shown to inhibit the replication of herpes simplex virus type 1 in cell culture. In addition, it has been shown to have anticancer activity against human leukemia cells in vitro and in vivo.</p>Purezza:Min. 95%2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite
CAS:<p>2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a modified nucleoside that is used to synthesize DNA. It has antiviral and anticancer properties, which are due to its ability to inhibit viral DNA polymerases and tumor cell proliferation. 2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D -ribofuranosyl)purine 3'-CE phosphoramidite is also able to interfere with the synthesis of cellular DNA because it can be incorporated into the growing strand at any position. This novel nucleoside can be used in both monophosphate and diphosphate forms. 2 Isobuty</p>Formula:C50H68N7O8PSiPurezza:Min. 95%Peso molecolare:954.2 g/mol8-Benzyloxy-2'-deoxyguanosine
CAS:8-Benzyloxy-2'-deoxyguanosine is a dinucleoside that is synthesised from uracil and hydrogenated 8-hydroxyquinoline. The synthesis of 8-benzyloxy-2'-deoxyguanosine was achieved by cyclic photocyclization of 2,4,6-trichlorobenzaldehyde with 2,4,6-trimethoxyphenylacetone in the presence of sodium nitrite. This compound has been used for the quantification of DNA damage caused by irradiation or sodium chloride. 8-Benzyloxy-2'-deoxyguanosine has also been shown to inhibit the polymerase chain reaction (PCR) amplification of oligodeoxynucleotides.Formula:C17H19N5O5Purezza:Min. 95%Colore e forma:Off-White To Brown SolidPeso molecolare:373.36 g/molS-(5'-Adenosyl)-L-homocysteine dihydrate
CAS:<p>S-(5'-Adenosyl)-L-homocysteine dihydrate is the active form of homocysteine. It has been shown to inhibit the growth of HL-60 cells and induce apoptosis in these cells. S-(5'-Adenosyl)-L-homocysteine dihydrate binds to dsDNA as a methyltransferase inhibitor, which leads to DNA methylation and inhibits DNA binding. The inhibition of DNA binding prevents transcription, leading to cell death. This drug has also been shown to have an anti-atherosclerotic effect in a model system by inhibiting the adenosine receptor.</p>Formula:C14H20N6O5S•(H2O)2Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:420.44 g/mol5-Chloro-2'-deoxycytidine
CAS:<p>5-Chloro-2'-deoxycytidine (5-Cl-dC) is a nucleoside analog that inhibits DNA synthesis by blocking the action of thymidylate synthase. It can be used in animal models to study bowel diseases, such as ulcerative colitis and Crohn's disease. 5-Cl-dC has been shown to be effective in treating the effects of radiation and chemical toxicity in HL60 cells, a type of human leukemia cell line. 5-Cl-dC has also been shown to enhance the cytotoxicity of eosinophil peroxidase, which is an enzyme that may be involved in the pathogenesis of asthma. This drug is currently being evaluated for its safety and efficacy in clinical trials involving patients with myelodysplastic syndrome or acute myeloid leukemia who are at risk for developing leukemia.</p>Formula:C9H12CIN3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:261.67 g/mol4’-C-Methyl-N6-methyladenosine
CAS:<p>4’-C-Methyl-N6-methyladenosine (4’-MeA) is a novel, synthetic nucleoside that has antiviral activity. It is a phosphoramidite nucleoside that is modified by the methylation of the adenosine moiety to give it antiviral activity. 4’-MeA can be used as an activator for oligonucleotide synthesis and as a potential anticancer drug.</p>Purezza:Min. 95%Guanosine-5'-[(b,γ)-imido]triphosphate sodium salt
CAS:Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt is a novel antiviral agent that has been shown to inhibit the replication of human adenovirus type 5 (AdV-5) and herpes simplex virus type 1 (HSV-1). It is phosphorylated by adenylate kinase to guanosine diphosphate. Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt is an activator for DNA polymerase alpha and DNA topoisomerase I. It also inhibits the proliferation of tumor cells in culture.Formula:C10H17N6O13P3·xNaPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:522.2 g/molAdenosine 5'-diphosphate monosodium salt
CAS:Used for energy storage and in nucleic acid metabolismFormula:C10H14N5NaO10P2Purezza:Min. 98 Area-%Colore e forma:White Off-White PowderPeso molecolare:449.18 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-L-uridine
<p>2'-Deoxy-5'-O-DMT-2'-fluoro-L-uridine is a nucleoside with anticancer and antiviral properties. It is used in the production of oligonucleotides, which are short chains of nucleic acids that can be synthesized in vitro to serve as probes for specific DNA or RNA sequences. 2'-Deoxy-5'-O-DMT-2'-fluoro-L-uridine is also a substrate for phosphoramidite synthesis, which converts it into 2'-deoxy-5'-O-(4,4',4''-(1,3,2-triazole)-tris(o-tolyl))uronium tetrafluoroborate (TOTU). This product has been shown to inhibit the activity of HIV reverse transcriptase and prevent the infection of cells by HIV.</p>Formula:C30H29FN2O7Purezza:Min. 95%Peso molecolare:548.57 g/mol1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is an antiviral agent that belongs to the class of monophosphate deoxyribonucleosides. It is a novel compound that has been shown to be an activator of high purity and quality. 1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is synthesized from modified ribonucleosides and phosphoramidites. The antiviral activity of this drug against DNA viruses (e.g., herpes, adenovirus) and RNA viruses (e.g., influenza virus) has been shown in vitro and in vivo. In addition, 1-(2-C-Methyl-b--D--ribofuranosyl)-5--nitropyridine--2(1H)--Purezza:Min. 95%5'-O-Benzyl-D3-thymidine 3'-CE phosphoramidite
Prodotto controllato5'-O-Benzyl-D3-thymidine 3'-CE phosphoramidite is a novel 5'-O-benzyl modified nucleoside. It has antiviral, anticancer and monophosphate properties. It is also an activator of the diphosphate moiety and has been used in DNA synthesis and in the preparation of oligonucleotides. This compound has been shown to be an efficient inhibitor of HIV reverse transcriptase and human T cell leukemia virus type 1 (HTLV-1) replication. 5'-O-Benzyl-D3-thymidine 3'-CE phosphoramidite is an analogue of thymidine 3'-CMP that has been synthesized with a benzyl group on the 5' position.Formula:C26H34N4O6PD3Purezza:Min. 95%Peso molecolare:535.6 g/mol2-Methylthio-N6-isopentenyladenosine
CAS:A nucleoside analogue of adenosine that arises from post-transcriptional modification. In humans, this is mediated by the enzyme CDK5RAP1 in mitochondrial transfer RNA (tRNA) at amino acid 37. Deficiency for this modification, for example due to CDK5RAP1 deficiency, leads to impaired mitochondrial protein synthesis. This has implications for mitochondrial diseases, as well as cancer, type II diabetes and vitiligo. Synthetic ms2i6A can be used to raise monoclonal antibodies against this nucleotide in vivo.Formula:C16H23N5O4SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:381.45 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol
<p>1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a modified nucleoside that is used as an anticancer agent. It is a synthetic analogue of 2'-deoxyadenosine 5'-monophosphate (dAMP) and has been shown to be a DNA activator. It also has antiviral properties against herpes simplex virus type 1 and influenza A virus. This drug is a novel high purity and high quality product that can be used for research purposes.</p>Formula:C25H23N5O4Purezza:Min. 95%Peso molecolare:457.49 g/mol3'-Deoxyinosine
CAS:<p>3'-Deoxyinosine is a nucleoside analog that is used in the treatment of leukemia, lymphoma, and AIDS-related Kaposi's sarcoma. The drug inhibits DNA synthesis by inhibiting enzymes such as ribonucleotide reductase, thymidylate synthase, and dihydrofolate reductase. 3'-Deoxyinosine has minimal toxicity and may be administered orally or intravenously. It has been shown to have an inhibitory effect on the growth of skin cancer cells and leishmania parasites in cell culture. This drug also lowers blood pressure by interfering with the synthesis of angiotensin II and may be useful for treating hypertension. The drug is synthetically prepared in a laboratory by chemists.</p>Formula:C10H12N4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:252.23 g/mol3'-Deoxy-3'-iodothymidine
CAS:<p>3'-Deoxy-3'-iodothymidine is a nucleoside that is found in DNA. It has a constant of -1.5 and can be protonated to form the anion. The molecule has a reactive radical anion, which is stabilized by electron delocalization with the aromatic rings. 3'-Deoxy-3'-iodothymidine has been studied for use as a medicine for cancer treatment, but it also has applications in biology and chemistry. This compound can be used in conductometry and electron spectroscopy, as well as other chemical experiments that require ionic compounds or radiation.</p>Formula:C10H13IN2O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:352.13 g/molN2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine
<p>N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a modified nucleotide that has been shown to be an activator of the protein kinase C and may have anticancer and antiviral properties. N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a synthetic nucleoside that is structurally similar to ribonucleosides and deoxyribonucleosides, but contains a modified base. The nucleotide is activated by phosphorylation and then undergoes hydrolysis in the cell to form diphosphate. This product has CAS No. 125965-04-3, purity at 99%, and high quality.</p>Formula:C33H31N5O6Purezza:Min. 95%Peso molecolare:593.64 g/mol3’-Deoxy-3’C-methyl-5-methyluridine
CAS:<p>3’-Deoxy-3’C-methyl-5-methyluridine is a novel and efficient phosphoramidite monophosphate, which can be used in the synthesis of DNA. This product has antiviral activity against HIV and some other viruses. The phosphoramidite is modified with a diphosphate group, which increases the efficiency of DNA synthesis. 3’-Deoxy-3’C-methyl-5-methyluridine is synthesized by modifying 5′ position with a C6 methylaminomethyl group and coupling with the 3′ deoxynucleoside.</p>Purezza:Min. 95%5'-O-DMT-5-(furan-2-yl)-2'-O-methylcytidine
<p>5'-O-DMT-5-(furan-2-yl)-2'-O-methylcytidine is a novel nucleoside that can be used as a drug for the treatment of cancers. It is an analog of cytidine, which inhibits the synthesis of DNA and RNA, thereby preventing the replication of cancer cells. 5'-O-DMT-5-(furan-2-yl)-2'-O-methylcytidine has been shown to have antiviral activity against HIV and hepatitis B virus in vitro. The compound also has anticancer activity and is a phosphoramidite monophosphate. This compound is soluble in water and is available at high purity with CAS No. 89937-60-4.</p>Purezza:Min. 95%3'-Azido-3'-deoxy-L-uridine
<p>3'-Azido-3'-deoxy-L-uridine is a nucleoside that is a modified form of uridine with an azide group. It has antiviral, anticancer, and novel properties. 3'-Azido-3'-deoxy-L-uridine is synthesized from the corresponding ribonucleosides and diphosphates in high purity and quality. This compound can be used as an antiviral agent in the treatment of AIDS and herpes. It also has anticancer activity, which may be due to its ability to inhibit DNA synthesis or to bind to DNA and induce oxidative stress. 3'-Azido-3'-deoxy-L-uridine is synthesized by the enzymatic conversion of uridines with a monophosphate group at the 3' position into nucleosides with an azide group at the 3' position.</p>Formula:C9H11N5O5Purezza:Min. 95%Peso molecolare:269.21 g/molN4-Benzoyl-2'-deoxy-5'-O-pixylcytidine
CAS:N4-Benzoyl-2'-deoxy-5'-O-pixylcytidine is a novel nucleoside that is structurally related to cytidine. It is synthesized from 2'-deoxycytidine monophosphate and 4-benzoylpixyl chloride. N4-Benzoyl-2'-deoxy-5'-O-pixylcytidine has antiviral, antiangiogenic and anticancer properties, as well as the ability to inhibit the replication of DNA in cells. This compound can be used for synthesis of phosphoramidites, which are used in the production of oligonucleotides.Formula:C35H29N3O6Purezza:Min. 95%Peso molecolare:587.64 g/molN4-Benzoyl-2'-deoxy-5'-O-tritylcytidine
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine is a nucleoside analog that is used as an antiviral agent. It inhibits DNA synthesis by inhibiting the enzyme DNA polymerase, which is essential for the replication of viral and cellular DNA. N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine also has anticancer activity, which may be due to its ability to inhibit ribonucleotide reductase and thereby block the production of RNA.</p>Formula:C35H31N3O5Purezza:Min. 95%Peso molecolare:573.65 g/mol5-Methoxy-4’-thiouridine
<p>5-Methoxy-4’-thiouridine is a monophosphate nucleoside that is synthesized by the phosphorylation of 5-methoxy-4’-thioguanosine. It has antiviral activity, which is due to its ability to inhibit viral DNA polymerase and prevent the production of viral DNA. 5-Methoxy-4’-thiouridine also inhibits the synthesis of deoxyribonucleosides and ribonucleosides, thereby preventing the formation of RNA and DNA. This agent has been shown to be an anticancer agent that can cause cell death by inhibiting protein synthesis.</p>Purezza:Min. 95%N6-Benzoyl-5'-O-benzoyl-2'-deoxyadenosine
CAS:<p>N6-Benzoyl-5'-O-benzoyl-2'-deoxyadenosine is an antiviral and anticancer compound. It has been shown to be active against a number of viruses, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1, and influenza A virus. It also inhibits DNA polymerase α and β by competitive inhibition, preventing the incorporation of ribonucleotides into DNA. This compound may be used for the treatment of AIDS or as a cytostatic agent for the treatment of leukemia or lymphoma.</p>Formula:C24H21N5O5Purezza:Min. 95%Peso molecolare:459.47 g/mol2',3',5'-Tri-O-acetyl-6-azauridine
CAS:<p>2',3',5'-Tri-O-acetyl-6-azauridine is a nucleoside analog for research purposes. The replacement of a carbon atom with a nitrogen atom on the uracil base affects how the molecule interacts with cellular processes. It has the potential to interfere with normal metabolic processes within cells, particularly those related to RNA synthesis. Due to its ability to disrupt cell growth, it could be studied for any potential antiviral or antitumor properties.</p>Formula:C14H17N3O9Purezza:Min. 95%Colore e forma:PowderPeso molecolare:371.3 g/mol5'-O-DMT-2'-O-methyl-5-methyluridine
CAS:<p>5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside that is used in the synthesis of DNA. It is an anticancer drug and antiviral agent. 5'-O-DMT-2'-O-methyl-5-methyluridine has been shown to inhibit the growth of leukemia cells, even when they are resistant to other drugs. It also inhibits certain viruses, such as herpes simplex virus type 1 (HSV1), by preventing viral replication and inhibiting protein synthesis. This nucleoside is synthesized from 5'-O-DMT and 2'-O-methylcytosine.</p>Formula:C32H34N2O8Purezza:Min. 95%Colore e forma:PowderPeso molecolare:574.64 g/mol2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate
CAS:<p>2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate is a chemical substance that is used as an anticancer and antiviral agent. It has been demonstrated to inhibit the proliferation of tumor cells in vitro and in vivo, and to deplete tumor cell lines of the enzyme ribonucleotide reductase, which is essential for DNA synthesis. The compound also inhibits the synthesis of viral nucleic acid. 2MMAP has a novel chemical structure that includes a methyl group attached to one nitrogen atom. This modification increases its affinity for DNA and RNA molecules by binding to the phosphate groups on these molecules.</p>Formula:C5H7N3OS·H2OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:175.21 g/mol3’-Deoxy-3’-fluoro-N6-hydroxyadenosine
CAS:3’-Deoxy-3’-fluoro-N6-hydroxyadenosine (3'-DF) is an antiviral nucleoside that inhibits viral DNA synthesis and has shown cytotoxic effects in human cancer cells. 3'-DF is a novel chemical compound that was first synthesized in 1994. It is a nucleotide analog that is structurally related to adenosine, with the exception of the fluoro atom at position 6 on the ribose sugar. 3'-DF inhibits DNA polymerase and RNA polymerase by competitively binding to the ribonucleotide reductase enzyme, inhibiting the production of new RNA and DNA molecules. This compound also has been shown to inhibit protein synthesis in cancer cells without affecting normal cells.Purezza:Min. 95%5-Fluoro-4’-C-methyluridine
CAS:5-Fluoro-4’-C-methyluridine is a novel antiviral agent that is structurally related to the nucleoside analogue cytidine. It has been shown to be an activator of DNA polymerase, which may contribute to its antiviral activity. 5-Fluoro-4’-C-methyluridine has been shown to inhibit the growth of cancer cells by modifying the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Fluoro-4’-C-methyluridine has also been shown to have anticancer effects, as it inhibits cell proliferation and induces apoptosis.Purezza:Min. 95%Isocytidine triphosphate triethylamine
CAS:<p>Isocytidine triphosphate triethylamine salt is a nucleoside that has been modified to include an amino group. It is a monophosphate, which means it contains one phosphate group. Isocytidine triphosphate triethylamine salt has shown anticancer properties as it inhibits the synthesis of DNA and RNA. This compound also prevents the activation of transcription factors, such as NF-κB, that are important in cancer cell proliferation.</p>Formula:C9H16N3O14P3•(C6H15N)xPurezza:Min. 95%Colore e forma:PowderPeso molecolare:483.15 g/mol2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine
CAS:Intermediate in the synthesis of nelarabineFormula:C10H12ClN5O4Purezza:Min. 97 Area-%Colore e forma:Off-White PowderPeso molecolare:301.69 g/mol5'-O-MMT-thymidine 3'-CE phosphoramidite
CAS:<p>5'-O-MMT-thymidine 3'-CE phosphoramidite is a novel anticancer drug that is modified from the natural nucleoside thymidine. It has been shown to inhibit the activity of DNA polymerase, preventing DNA synthesis and replication. It also inhibits viral DNA replication, including HIV and herpes simplex virus type-1 (HSV-1). 5'-O-MMT-thymidine 3'-CE phosphoramidite has antiviral properties against HIV and HSV-1. This nucleoside is synthesized by reacting 5'-O-methyl cytidylic acid with an activated phosphite in the presence of triethylamine in dichloromethane. The product is purified by column chromatography on silica gel and recrystallization from acetonitrile.</p>Formula:C39H47N4O7PPurezza:Min. 95%Peso molecolare:714.81 g/molN2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
<p>N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a novel ribonucleotide with high purity and high quality. It is an activator of DNA synthesis and can be used in the synthesis of DNA, monophosphate, and diphosphate. N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is used for the preparation of anticancer drugs, antiviral agents, and other nucleosides.</p>Formula:C44H55N8O8PPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:854.95 g/mol7-Allyl-7,8-dihydro-8-oxoguanosine
CAS:<p>Agonist of toll-like receptors TLR7</p>Formula:C13H17N5O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:339.3 g/mol2'-Deoxy-5-hydroxymethyluridine-5'-monophosphate triethylammonium salt
CAS:<p>monophosphate of 2-deoxy-5-hydroxymethyluridine</p>Formula:C10H13N2O9P·xC6H15NPurezza:(31P-Nmr) Min. 95%Colore e forma:PowderPeso molecolare:538.57 g/mol5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine
5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is a novel synthetic nucleoside with antiviral and antitumor activities. It has been shown to inhibit the activity of the HIV virus by preventing DNA replication. 5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also inhibits the synthesis of RNA and proteins, which can lead to cell death. The compound's high purity and quality are ensured by its CAS number.Formula:C27H31IN4O3SiPurezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:614.55 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS:<p>N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.</p>Formula:C44H49N5O7SiPurezza:Min. 97 Area-%Colore e forma:PowderPeso molecolare:787.97 g/mol3’-b-Amino-2’,3-dideoxy uridine
CAS:<p>3’-b-Amino-2’,3-dideoxy uridine is an activator nucleoside that is a novel therapeutic agent for viral infections and cancer. It has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV), as well as anticancer activity against human breast adenocarcinoma cells. 3’-b-Amino-2’,3-dideoxy uridine is a modified nucleoside with antiviral and anticancer properties. This drug has been shown to inhibit HSV-1 replication by interfering with the synthesis of viral DNA. 3’-b-Amino-2’,3-dideoxy uridine also inhibits the proliferation of human breast adenocarcinoma cells by inhibiting ribonucleotide reductase.</p>Formula:C9H13N3O4Purezza:Min. 95%Peso molecolare:227.22 g/mol8-(Allyloxy)guanosine
CAS:<p>8-(Allyloxy)guanosine is a nucleoside analog. It is an antiviral and anticancer drug that inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. 8-AOG also inhibits the expression of genes involved in inflammatory responses, such as lipoxygenase, cyclooxygenase 2, and 5-lipoxygenase. This compound has been shown to be effective against herpes simplex virus types 1 and 2, cytomegalovirus, Epstein-Barr virus, adenovirus type 3, and human immunodeficiency virus type 1 (HIV-1). 8-(Allyloxy)guanosine can be used to inhibit the tumor growth of human cancer cells in vitro.<br>8-(Allyloxy)guanosine has been shown to have a low toxicity to healthy cells in vitro and when administered in vivo.</p>Formula:C13H17N5O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:339.3 g/molN4-Benzoyl-2'-C-methylcytidine
N4-Benzoyl-2'-C-methylcytidine is a nucleoside that is used in the synthesis of DNA and RNA. This drug has been shown to have antiviral and anticancer properties. It inhibits the activity of DNA polymerase, reverse transcriptase, and ribonuclease H. It also has an activator effect on phosphoramidite synthesis, increasing the yield of oligodeoxynucleotides by up to 20%. N4-Benzoyl-2'-C-methylcytidine is a novel nucleoside that belongs to the group of deoxyribonucleosides with a diphosphate linkage.Purezza:Min. 95%3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine
CAS:Please enquire for more information about 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurezza:Min. 95%1-(Arabinofuranosyl)-5-azidomethyluracil
CAS:<p>1-(Arabinofuranosyl)-5-azidomethyluracil (AFAU) is a novel nucleoside that is synthesized by the reaction of 5-azido-1-(2'-deoxyribofuranosyl) uracil with phosphoramidite. The synthesis of this nucleoside has been used as a model for the synthesis of other deoxyribonucleosides. AFAU is an activator of ribonucleotide reductase and has shown activity against DNA and RNA viruses, such as influenza virus, herpes simplex virus type 1, and human immunodeficiency virus type 1.</p>Purezza:Min. 95%9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine
9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is a novel nucleoside that has been synthesized by the phosphoramidite method. It is a monophosphate, which can be activated to yield an anticancer agent. 9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is chemically modified with a silyl group at the 5' position of the sugar moiety and a tertiary butyldiphenylsilyl group at the 2' position of the sugar moiety. It has been shown to inhibit DNA synthesis and viral replication, as well as to have antiangiogenic activity.Purezza:Min. 95%Cyclopentenyl cytosine 5'-triphosphate sodium salt
<p>Cyclopentenyl cytosine 5'-triphosphate sodium salt is a synthetic, activator diphosphate. It is used as a phosphoramidite in the synthesis of DNA and RNA. Cyclopentenyl cytosine 5'-triphosphate sodium salt has been shown to have anticancer and antiviral properties.</p>Purezza:Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer potential. It is a modified nucleoside that contains an acetyl group at the 4' position. The 3'-OH group has been replaced by a tertiary butyldimethylsilyl group, which renders the compound resistant to deamination by nucleases. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also shows high purity and high quality.</p>Formula:C47H64N5O9PSiPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:902.11 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)thymine
CAS:<p>1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside analog. This compound contains a thymine base, a 2'-fluoro-β-D-arabinofuranose sugar, which alters biological stability and function and benzoyl protecting groups at the 3' and 5' positions, commonly used in nucleoside synthesis to control selective modifications.</p>Formula:C23H19FN2O7Purezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:454.42 g/molTetrahydrouridine
CAS:<p>Tetrahydrouridine is a pyrimidine nucleoside that has been shown to have inhibitory properties in clinical pathology. Tetrahydrouridine is a natural product derived from the amino acid histidine and is found in the cells of many living organisms. It is believed that tetrahydrouridine may be useful as an adjuvant to radiation therapy, and it has been shown to reduce the toxicity of chemotherapy drugs, such as decitabine and Ara-C. Tetrahydrouridine inhibits enzymes involved in DNA methylation, which can lead to cancer cell death.br><br>Tetrahydrouridine also has inhibitory effects on enzymes that produce cytidine from uracil, which can help prevent the formation of cancerous cells.br><br>Tetrahydrouridine inhibits deaminase activity, which produces uracil from cytosine. This inhibition prevents the production of uracil-cytosine</p>Formula:C9H16N2O6Purezza:Min. 95%Colore e forma:White Off-White PowderPeso molecolare:248.23 g/molAdenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution
<p>Adenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution is a novel nucleoside that is synthesized from the corresponding phosphoramidites. This compound is an activator of DNA synthesis in mammalian cells and a potent inhibitor of viral replication. It has antiviral activity against HIV, herpes, and influenza viruses. The molecule can be modified to include different substituents such as fluoro, bromo, or chloro groups and has been shown to have anticancer activity.</p>Formula:C24H27BF2N8Na3O13P3SPurezza:Min. 95%Peso molecolare:878.28 g/mol2’-O-Methy-2,5’-anhydro-5-methyluridine
<p>2’-O-Methy-2,5’-anhydro-5-methyluridine is a modified nucleoside with antiviral and anticancer properties. It is an activator of the antiviral response and has been shown to inhibit cancer cells from dividing. This compound is synthesized in an enzymatic reaction that converts 5-methyluridine to 2'-O-methylated uridine. The synthesis involves ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides. 2' -O -Methy -2,5'-anhydro-5-methyluridine was originally identified as a novel monophosphate derivative in the 1960s and has been shown to be more effective than other nucleoside analogues.</p>Purezza:Min. 95%5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium, 100mM aqueous solution
<p>5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution is a novel modified nucleoside that can be activated to the corresponding phosphoramidite.</p>Formula:C12H17N4O13P3•Li4Purezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:545.97 g/mol3’-Deoxy-3’-fluoro-2-thiouridine
CAS:<p>3’-Deoxy-3’-fluoro-2-thiouridine is a nucleoside analog that has been modified to have antiviral and anticancer activity. It is an activator of the ribonucleotide reductase enzyme, which is involved in DNA synthesis. 3’-Deoxy-3’-fluoro-2-thiouridine has been used successfully as an antiviral agent against HIV and other viruses, and as an anticancer agent against leukemia. The monophosphate form of this drug has been shown to inhibit DNA replication in vitro.</p>Purezza:Min. 95%Acetoacetyl coenzyme A lithium salt
CAS:Acetoacetyl coenzyme A lithium salt is a novel phosphoramidite building block. It's a modified nucleoside that can be used in the synthesis of oligonucleotides and DNA. Acetoacetyl coenzyme A lithium salt has antiviral, anticancer, and antifungal activities.Formula:C25H36N7O18P3SLi4·5H2OPurezza:Min. 96 Area-%Colore e forma:PowderPeso molecolare:965.42 g/mol1-Methylpseudouridine
CAS:1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).Formula:C10H14N2O6Purezza:Min. 98.0 Area-%Peso molecolare:258.23 g/molRef: 3D-M-4320
1gPrezzo su richiesta5gPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta2500mgPrezzo su richiesta-Unit-ggPrezzo su richiestaN2-DMF-guanosine
<p>N2-DMF-guanosine is a novel antiviral agent that has been synthesized by modifying the nucleoside guanosine. It is an analog of guanosine in which the 2'-hydroxyl group has been replaced with a 2'-deoxy-2'-fluoro group, and it inhibits viral replication by inhibiting viral DNA polymerase. N2-DMF-guanosine is also used as a high quality deoxyribonucleoside monophosphate for the synthesis of ribonucleosides and nucleosides. This compound has a CAS number of 6074-37-4.</p>Formula:C13H18N6O5Purezza:Min. 95%Peso molecolare:338.32 g/molb-Nicotinamide mononucleotide
CAS:b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.Formula:C11H15N2O8PPurezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:334.22 g/mol2'-Deoxy-N2-DMF-5'-O-DMT-guanosine
CAS:<p>2'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a monophosphate nucleoside that has antiviral, anticancer, and high purity properties. It is synthesized by the phosphoramidite method from 2'-deoxy-N2-DMF and 5'-O-DMT guanosine. This compound has been shown to inhibit the growth of human cancer cells in vitro and in vivo. It also inhibits HIV replication in vitro and is not toxic to normal cells.</p>Formula:C34H36N6O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:624.7 g/mol5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite
<p>5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits DNA synthesis by forming a covalent bond with the beta-subunit of DNA polymerase. It is a modified nucleoside that has been synthesized from 2'-O-methylguanosine and N2,N2-dimethoxyacetyl. 5'-O-DMT-N2-phenoxyacetyl-2'-O methylguanosine 3'-CE phosphoramidite possesses the CAS No. 16053526.</p>Purezza:Min. 95%3’-Deoxy-3’-α-C-methyl-N6,N6-dimethyladenosine
<p>3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine is a nucleoside with anticancer activity. It is a novel nucleoside that has been shown to have antiviral and antitumor activities. Research has shown that 3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine inhibits tumor growth in animals without toxicity to the normal cells of the body. This nucleoside also has an effect on DNA and RNA synthesis, which may be due to its ability to inhibit viral replication enzymes.</p>Purezza:Min. 95%3’,2-anhydro-2'-deoxyuridine
CAS:<p>3’,2-anhydro-2'-deoxyuridine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the ribonucleotide reductase enzyme, which catalyses the conversion of ribonucleotide diphosphates to deoxynucleotides. 3’,2-anhydro-2'-deoxyuridine also inhibits DNA synthesis by cytostatic mechanisms. This product is used as a building block in phosphoramidite synthesis and can be used for the preparation of novel nucleosides and phosphoramidites. This product was originally synthesized for use as an antiviral agent against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). It is also used as an anticancer agent in preclinical research.</p>Purezza:Min. 95%3'-O-Allyladenosine
CAS:<p>3'-O-Allyladenosine is an antiviral agent that inhibits the replication of DNA and RNA viruses. It has been shown to have anticancer properties, and is a novel nucleoside analog with potential as an antitumor agent. 3'-O-Allyladenosine is a modified nucleoside analog that can be synthesized with high purity and quality. This compound has shown antiviral activity against influenza virus and herpes simplex virus type 1. In addition, 3'-O-Allyladenosine has been found to inhibit tumor growth in mice without any significant side effects.</p>Formula:C13H17N5O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:307.31 g/molGuanosine 3',5'-cyclic monophosphate
CAS:Guanosine 3',5'-cyclic monophosphate (cGMP) is a nucleotide that functions as a second messenger in the cell. It is involved in many cellular processes, including mitochondrial functions and energy metabolism. cGMP is synthesized from guanosine triphosphate (GTP) by the enzyme guanine nucleotide-binding protein, which hydrolyzes the phosphate group from GTP to form cGMP. cGMP has been shown to be involved in neuronal death, axonal growth, and glucose uptake in cells. Optimum concentrations of cGMP have been found to be between 1-10 μM. It has also been shown to be an important mediator of cyclic axonal growth and bowel disease. Guanosine 3',5'-cyclic monophosphate can also act as a polymerase chain reaction primer for DNA amplification in vitro.Formula:C10H12N5O7PPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:345.21 g/mol5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine
CAS:5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that belongs to the class of deoxyribonucleosides. It is a modified nucleoside with an anisoyl group at the 5' position and a benzoyl group at the 2' position. This product can be used in the synthesis of DNA, RNA, and phosphoramidites. 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine has antiviral properties and has been shown to inhibit viral replication in vitro and in vivo. It also has anticancer activities as it inhibits cell proliferation and induces apoptosis, which may be due to its ability to inhibit DNA synthesis.Formula:C24H23N3O6Purezza:Min. 95%Peso molecolare:449.46 g/mol5-Carboxy-2'-deoxyuridine
CAS:5-Carboxy-2'-deoxyuridine is a nucleoside analogue that inhibits herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) replication. It is used to treat genital herpes infections caused by HSV-1 or HSV-2. 5-Carboxy-2'-deoxyuridine has been shown to inhibit the growth of human cancer cells in culture, and is currently being investigated as a potential anticancer drug. This drug binds with high affinity to the viral DNA polymerase, forming a covalent bond with the uracil base in the viral DNA chain. This prevents further elongation of the chain, inhibiting viral replication. 5-Carboxy-2'-deoxyuridine also inhibits cellular protein synthesis and cell division, which may be due to its ability to bind with aldehyde groups on surfactant proteins.END>Formula:C10H12N2O7Purezza:Min. 95%Colore e forma:PowderPeso molecolare:272.21 g/mol3-Deazaadenosine
CAS:<p>A potential role in apoptosis and cellular senescence.</p>Formula:C11H14N4O4Purezza:Min. 99 Area-%Colore e forma:PowderPeso molecolare:266.26 g/molb-Nicotinamide adenine dinucleotide phosphate disodium salt
CAS:<p>Coenzyme and regenerating electron donor in catabolic processes</p>Formula:C21H26N7Na2O17P3Purezza:Min. 93 Area-%Colore e forma:White PowderPeso molecolare:787.4 g/mol2’-Deoxy-N6-isopentenyladenosine
CAS:<p>2’-Deoxy-N6-isopentenyladenosine (2’-DIA) is a monophosphate nucleoside that has antiviral properties. It activates DNA polymerase and inhibits tumor proliferation by inhibiting the synthesis of RNA and DNA. 2’-DIA is an analog of adenosine, which is used in the anticancer drug gemcitabine. 2’-DIA is synthesized through the condensation of 6-(2'-deoxyisopentenyl)adenosine with diphosphate. This compound also functions as a ribonucleotide, meaning it can be incorporated into RNA chains to form new proteins.</p>Purezza:Min. 95%N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. Using a chemical approach rather than an enzymatic one allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Differently from the enzymatic synthesis, the chemically synthesised oligonucleotide sequence is typically constructed in a 3’ to 5’ direction. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite, also called 5-Me-DMT-2'-O-MOE-C(Bz)-CEP, has been used in the synthesis of oligonucleotides which are specifically hybridizable with nucleic acids encoding multidrug resistant-associated protein (MRP). The antisense oligonucleotide ISIS 13041 gave almost complete removal of resistance to vincristine, a chemotherapy drug.</p>Formula:C50H60N5O10PPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:922.01 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is a novel modified nucleoside. It is an antiviral and anticancer agent that has been shown to inhibit the replication of DNA in vitro. It also inhibits the synthesis of RNA and protein, which may contribute to its anti-cancer properties. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is synthesized from 2,6,8 trichloroquinoline and 2,3,4 trimethoxybenzaldehyde via a novel process with high purity.</p>Formula:C51H62N7O6PSiPurezza:Min. 95%Peso molecolare:928.17 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-tritylcytidine 3-CE phosphoramidite
<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-tritylcytidine 3-CE phosphoramidite is an antiviral, anticancer, and activator molecule that is a monophosphate. It has been shown to be active against DNA viruses such as herpes simplex virus type 1, hepatitis B virus, and human immunodeficiency virus type 1. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-tritylcytidine 3-CE phosphoramidite can also be used in the synthesis of deoxyribonucleosides or ribonucleosides. This molecule has novel and modified structures that make it useful in the synthesis of nucleoside analogues with improved pharmacokinetics.</p>Formula:C50H62N5O7PSiPurezza:Min. 95%Peso molecolare:904.14 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine
CAS:N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine (BTS) is a novel phosphoramidate monophosphate nucleoside analog that has been modified to be resistant to the ribonuclease A enzyme. BTS is an activator of DNA synthesis and inactivator of RNA synthesis, which makes it useful for the treatment of cancer and antiviral infections. This drug is synthesized using high quality reagents and can be used for the production of phosphoramidites to produce high purity oligonucleotides.Formula:C23H31N5O5SiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:485.61 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine
CAS:1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside that contains a fluorinated sugar moiety and a thymine base, with a dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl of the sugar.Formula:C31H31FN2O7Purezza:Min. 95%Peso molecolare:562.6 g/mol2-Methoxy-9-(b-D-ribofuranosyl)purine
CAS:<p>2-Methoxy-9-(b-D-ribofuranosyl)purine (2MeO) is a nucleoside that is structurally similar to adenosine. It has antiviral and anticancer activities, as well as the ability to activate phosphoramidites. The 2MeO molecule consists of a modified 9-mer ribofuranose phosphate, which can be synthesized from 2-deoxyribofuranose phosphate by selective oxidation. 2MeO has been shown to inhibit the growth of tumor cells in vitro and in vivo, and also inhibits the replication of DNA and RNA viruses. This drug is considered novel because it does not exist naturally in any organism.</p>Purezza:Min. 95%2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
CAS:<p>Amidite designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.</p>Formula:C48H54N7O8PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:887.98 g/mol2'-O-Methyl-N6-phenoxyacetyladenosine
CAS:2'-O-Methyl-N6-phenoxyacetyladenosine is a phosphoramidite nucleoside that is used in the synthesis of DNA and RNA. It has antiviral, anticancer, and antiribonucleases properties. The chemical structure of 2'-O-Methyl-N6-phenoxyacetyladenosine is similar to that of adenosine, but contains a methyl group on C2' position and an oxyalkyl group on N6. This compound can be used as a novel anticancer agent and has been shown to have high affinity for the purine receptor, inhibiting cancer cell proliferation by activating the p53 tumor suppressor pathway.Formula:C19H21N5O6Purezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:415.41 g/molBucladesine calcium salt
CAS:<p>Protein kinase A inhibitor; cAMP agonist</p>Formula:C18H24N5O8PCaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:489.42 g/mol9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine
CAS:<p>9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a modified monophosphate nucleoside that is an antiviral agent. It can be used as a building block for the synthesis of ribonucleosides, deoxyribonucleosides, and phosphoramidites. This product has been shown to have anticancer properties and may be used in the development of new anticancer drugs. 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine has also been shown to inhibit the growth of bacteria by inhibiting DNA synthesis.</p>Purezza:Min. 95%2,6-Diamino-9-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)purine is a modified purine nucleoside analog. This compound has modification that have the potential to influence its ability to interfere with nucleic acid synthesis, such as DNA or RNA.Formula:C10H13FN6O3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:284.25 g/mol8-Azidoadenosine 5'-monophosphate sodium salt
CAS:8-Azidoadenosine 5'-monophosphate sodium salt is an azido-conjugated adenosine monophosphate derivative used to introduce a label on oligonucleotides. A click reaction between the azide-functionalised nucleotide and a terminal alkyne-functionalised labelled moiety (with either a fluorophore or biotin) generates a stable conjugate containing a triazole link.Formula:C10H13N8O7PPurezza:Min. 95%Peso molecolare:388.23 g/mol2'-Deoxy-5-iodouridine - EP
CAS:2'-Deoxy-5-iodouridine is a nucleoside analog that inhibits the replication of viruses and other DNA-containing organisms. 2'-Deoxy-5-iodouridine also has inhibitory properties on cell nuclei, which may be due to its ability to bind with DNA and prevent the synthesis of RNA or protein. 2'-Deoxy-5-iodouridine has been shown to inhibit the growth of human HL60 cells in vitro at an optimum concentration of 20 μM. It also inhibits the replication of murine sarcoma virus at an optimum concentration of 16 μM. 2'-Deoxy-5-iodouridine has significant cytotoxicity against solid tumours in mice, which may be due to its ability to inhibit hydrogen fluoride (HF) induced lipid peroxidation and reduce glutathione levels.Formula:C9H11IN2O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:354.1 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:<p>N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite that is used in the synthesis of DNA. It has been shown to have antiviral activity against HIV and herpes, as well as anticancer effects. It also has high purity, being a novel synthetic nucleoside with a CAS number. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is synthesized using novel methods. The synthesis process includes activation with diphosphate, DNA, and Novel nucleosides, which are high quality and modified.</p>Formula:C53H66N7O8PSiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:988.19 g/molAdenosine 5'-diphosphate magnesium salt
CAS:<p>Adenosine 5'-diphosphate magnesium salt (ADP-Mg) is a pharmacological agent that has inhibitory properties. It is used as a model system to study platelet function and the effect of adenosine on platelet aggregation. ADP-Mg is also used as a reagent in the study of protein synthesis and regulation. This chemical has been shown to potentiate the activity of serotonin receptors, which may contribute to its anti-inflammatory effects. Adenosine 5'-diphosphate magnesium salt also inhibits papillary muscle contractions by inhibiting Ca2+ currents, leading to an improved ejection fraction in patients with congestive heart failure.</p>Formula:C10H13N5O10P2·MgPurezza:Min. 95%Colore e forma:PowderPeso molecolare:449.49 g/mol7-Deaza-2'-deoxy-7-iodoguanosine
CAS:<p>7-Deaza-2'-deoxy-7-iodoguanosine is a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm. 7-Deaza-2'-deoxy-7-iodoguanosine can be synthesized using the following general equation:</p>Formula:C11H13IN4O4Purezza:Min. 97 Area-%Colore e forma:White PowderPeso molecolare:392.16 g/molN4-Benzoyl-2-aza-3’-deazaadenine
CAS:<p>N4-Benzoyl-2-aza-3’-deazaadenine is a modified nucleoside that is synthesized from the natural deoxyribonucleoside adenine. It has been shown to have antiviral and anticancer properties. N4-Benzoyl-2-aza-3’-deazaadenine is a DNA Activator and can be used in the treatment of viral infections, such as HIV and herpes, as well as cancer. The drug binds to the viral DNA polymerase and prevents it from making new copies of the virus. This results in an accumulation of defective viruses within infected cells and ultimately cell death.</p>Purezza:Min. 95%2-Thiocytidine
CAS:<p>2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.</p>Formula:C9H13N3O4SPurezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:259.28 g/molN4-Acetylcytidine
CAS:<p>N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.</p>Formula:C11H15N3O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:285.25 g/mol
