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Nucleosidi

Nucleosidi

I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.

Trovati 3569 prodotti di "Nucleosidi"

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  • 6-Dimethylamino-9-(b-D-ribofuranosyl)purine

    CAS:
    <p>6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.</p>
    Formula:C12H17N5O4
    Purezza:Min. 98 Area-%
    Colore e forma:White Powder
    Peso molecolare:295.3 g/mol

    Ref: 3D-ND04708

    1g
    405,00€
    5g
    1.179,00€
    2500mg
    766,00€
  • 5-Hydroxycytidine

    CAS:
    <p>5-Hydroxycytidine is a pyrimidine nucleoside that is found in DNA and RNA. It can be produced by the conversion of cytidine 5-monophosphate to cytidine 5'-diphosphate, which is then hydrolyzed to produce 5-hydroxycytidine. This conversion requires the enzyme cytidylate kinase. The structure of 5-hydroxycytidine differs from other pyrimidine nucleosides as its hydroxyl group does not have an acidic proton present. Biological functions that have been attributed to 5-hydroxydihydrocytidylic acid include its ability to inhibit translation and induce cell death in lung cells. This compound has also been shown to modify DNA duplexes and form bioconjugates with proteins or small molecules, such as fluorescein and digoxigenin. These modifications are used in analytical methods such as phase chromatography, nuclear magnetic resonance spectroscopy</p>
    Formula:C9H13N3O6
    Purezza:Min. 95 Area-%
    Colore e forma:Powder
    Peso molecolare:259.22 g/mol

    Ref: 3D-NH159404

    25mg
    478,00€
    50mg
    766,00€
    100mg
    1.181,00€
    250mg
    2.237,00€
    500mg
    3.195,00€
  • 1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil

    CAS:
    1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil is a novel, anticancer drug. It is active against both RNA and DNA viruses, such as HIV, influenza virus and herpes virus. 1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil has been shown to be an activator for phosphoramidites in aqueous solution. This compound is of high purity with CAS No. 2072145–25–4. It is also a synthesized, monophosphate nucleoside that can be used in the production of modified nucleosides for therapeutic purposes or as antiviral agents
    Purezza:Min. 95%

    Ref: 3D-ND162854

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  • 3'-Amino-3'-deoxy-D3-thymidine

    Prodotto controllato

    <p>3'-Amino-3'-deoxy-D3-thymidine is a novel, modified nucleoside of the deoxyribonucleosides group. It is an activator of ribonucleotide reductase and has antiviral properties. 3'-Amino-3'-deoxy-D3-thymidine is an anticancer agent that induces DNA synthesis and inhibits RNA synthesis.</p>
    Formula:C10H12N3O4D3
    Purezza:Min. 95%
    Peso molecolare:244.27 g/mol

    Ref: 3D-NA09014

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  • 5-(Azidomethyl)-2’-deoxyuridine

    CAS:
    <p>5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.</p>
    Formula:C10H13N5O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:283.24 g/mol

    Ref: 3D-NA162993

    1g
    4.915,00€
    25mg
    428,00€
    50mg
    635,00€
    100mg
    1.020,00€
    250mg
    2.102,00€
  • 6- Hydroxycytidine

    CAS:
    <p>6-Hydroxycytidine is a modified nucleoside that is used as a building block in the synthesis of DNA. It has antiviral activity and has been shown to be effective in treating cancer cells. 6-Hydroxycytidine is also used in the production of phosphoramidites, which are used to synthesize nucleotides for DNA and RNA. 6-Hydroxyl cytidine is a novel chemical that does not have an IUPAC name. CAS No: 15477-67-5</p>
    Formula:C9H13N3O6
    Purezza:Min. 95%
    Peso molecolare:259.22 g/mol

    Ref: 3D-NH172586

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  • 8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt

    CAS:
    Activator of cGMP-dependent protein kinases
    Formula:C10H10BrN5NaO7P
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:446.08 g/mol

    Ref: 3D-NB07973

    1g
    1.366,00€
    25mg
    267,00€
    50mg
    382,00€
    100mg
    509,00€
    250mg
    807,00€
  • 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine


    <p>2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is a novel nucleoside analog that has been shown to have anticancer, antiviral and antiretroviral activities. It binds to the ribonucleotide reductase enzyme and inhibits deoxyribonucleoside synthesis in cells. 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is also an activator of ribonucleotide reductase. This drug has been shown to be effective in treating leukemia, lymphoma, and breast cancer cells.</p>
    Formula:C23H21N3O5
    Purezza:Min. 95%
    Peso molecolare:419.44 g/mol

    Ref: 3D-NA09232

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  • 7-Iodo-7-deaza-2'-C-methylguanosine


    7-Iodo-7-deaza-2'-C-methylguanosine has antiviral activity and is used as a building block in the synthesis of DNA and RNA molecules. 7-Iodo-7-deaza-2'-C-methylguanosine is a novel synthetic nucleoside that has anticancer properties and is used for the treatment of different types of cancer. It is also used for the prevention of viral infections, such as influenza. This product has high purity and is available in its phosphate or monophosphate form.
    Purezza:Min. 95%

    Ref: 3D-NI14082

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  • 5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine


    <p>5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is a deoxyribonucleoside that has antiviral, anticancer, and novel properties. It has a CAS No. of 49811-91-7 and a molecular weight of 290.5 g/mol. The chemical formula for 5'-0-p-anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is C12H14FN2O9. It is synthesized by reacting 2,6-(1H,1'H)-benzoxazinones with 3' -deoxycytidines in the presence of phosphoric acid and anhydrous zinc chloride in methanol at room temperature to form the 5'-0 p anisoyl derivative, which is then reacted with</p>
    Formula:C24H22FN3O6
    Purezza:Min. 95%
    Peso molecolare:467.45 g/mol

    Ref: 3D-NA08685

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  • 3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone

    CAS:
    3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone is a novel synthetic nucleoside. It is an activation agent that releases 2'-deoxyuridine 5'-triphosphate from ribonucleotides. This nucleoside has been shown to have antiviral and anticancer properties, as well as the ability to inhibit HIV replication in vitro. It is also used for the preparation of oligonucleotide analogs for use in molecular biology research and molecular medicine.
    Purezza:Min. 95%

    Ref: 3D-NB163170

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  • 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine

    CAS:
    5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine is a monophosphate antiviral agent. It has been shown to inhibit the activity of DNA and RNA polymerases in vitro. The drug is novel, and its antiviral properties have not been tested in vivo. 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine has been synthesized using phosphoramidites and was found to be of high quality and purity. It has also been modified at the 2' position with an acetyl group and at the 3' position with a levulinoyl group.
    Purezza:Min. 95%

    Ref: 3D-ND163002

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  • 2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine

    CAS:
    2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine is a novel nucleoside that has been modified to be phosphorylated on the 5' position. This modification provides the molecule with more stability in vivo and increases its anticancer potential. The synthesis of 2'-amino-2'-deoxy-5'-O-DMT-5 methyluridine is carried out by the conversion of 5'-O-(4,4'-dimethoxytrityl)-N,N-diisopropylphosphoramidite to 5'-O-(4,4'-dimethoxytrityl)-2',3',6'-triisopropylbenzoylphosphate. This compound can also inhibit viral replication by inhibiting dsRNA synthesis and is used to treat patients with chronic hepatitis B virus infection. The molecule has high purity and high quality.
    Purezza:Min. 95%

    Ref: 3D-NA144650

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  • 7-Deazaadenosine- 2', 3'- dideoxy- 7[3- (trifluoroacetyl) amino] - 1- propyn- yl

    CAS:
    <p>7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.</p>
    Formula:C16H16F3N5O3
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:383.33 g/mol

    Ref: 3D-ND156888

    10mg
    135,00€
    25mg
    201,00€
    50mg
    286,00€
    100mg
    449,00€
    250mg
    787,00€
  • 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D- ribo-hex-5-enofu ranosyl]uracil


    5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.
    Purezza:Min. 95%

    Ref: 3D-NB162929

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  • 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite


    <p>2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite is a novel, modified nucleoside. It is a monophosphate and can be used as antiviral, activator or diphosphate. It has been shown to inhibit the growth of cancer cells in vitro. 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite also has activity against bacterial and viral pathogens and can be used for the synthesis of DNA, RNA, and other oligonucleotide compounds. This product is of high quality and purity with CAS No., Antiviral, Activator, diphosphate, Synthetic, Ribonuclesides, Deoxyribonucleosides.</p>
    Formula:C37H42FN4O6P
    Purezza:Min. 95%
    Peso molecolare:688.74 g/mol

    Ref: 3D-PD09190

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  • 2'-O-tert-Butyldimethylsilyladenosine

    CAS:
    2'-O-tert-Butyldimethylsilyladenosine is a novel nucleoside. It is an anti-cancer and antiviral agent that is synthesized from ribonucleosides by the phosphoramidite method. 2'-O-tert-Butyldimethylsilyladenosine has been shown to be active against DNA polymerases, RNA polymerases, and enveloped viruses. This drug also inhibits cell proliferation in a variety of human tumor cells in vitro. 2'-O-tert-Butyldimethylsilyladenosine has been shown to exhibit anticancer activity by interfering with DNA synthesis and preventing the replication of damaged cells.
    Purezza:Min. 95%

    Ref: 3D-NB15545

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  • N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite


    <p>N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits the growth of cancer cells. It is a modified nucleoside that has been used to synthesize phosphorothioate oligonucleotides and has been shown to have antiviral and anticancer activities. This compound binds with high affinity to the active site of DNA polymerase, preventing incorporation of ribonucleosides into DNA. N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is an activator that increases the rate of deoxyribonucleotide synthesis by DNA polymerase.</p>
    Purezza:Min. 95%

    Ref: 3D-PD64043

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  • 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine

    CAS:
    2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is a novel phosphoramidite nucleoside that is an antiviral and anticancer agent. It can be used as a monophosphate or diphosphate. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine has been shown to inhibit the replication of DNA, RNA, and protein synthesis. This compound also has an activating effect on the immune system by inducing lymphocyte proliferation and increasing NK activity. It inhibits the growth of viruses such as HIV and influenza A virus. The purity of 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is high, with a CAS number of 11052282-2.
    Formula:C39H37N5O7
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:687.76 g/mol

    Ref: 3D-ND08050

    1g
    327,00€
    5g
    709,00€
    10g
    1.051,00€
    25g
    1.834,00€
    500mg
    221,00€
  • 2'-Deoxycytidine HCl

    CAS:
    2'-Deoxycytidine HCl is a nucleoside analogue that is used as a radiation sensitizer in the treatment of tumors. It is converted into 2'-deoxycytidine-5'-triphosphate by incorporation into DNA during replication and inhibits DNA synthesis. This compound has been shown to have anti-leukemic activity against murine leukemia virus (MLV) and murine sarcoma virus (MSV) in mice, although it does not inhibit the proliferation of Swiss-Webster mice. The protonated form of 2'-deoxycytidine HCl has been observed using nuclear magnetic resonance spectroscopy, with a cyclohexane ring as the proton acceptor. The monosodium salt also forms a stable complex with amino groups, which may be due to its acidic ph.
    Formula:C9H13N3O4·HCl
    Purezza:Min. 98 Area-%
    Colore e forma:White Powder
    Peso molecolare:263.68 g/mol

    Ref: 3D-ND02591

    5g
    476,00€
    10g
    632,00€
    25g
    894,00€
    50g
    1.260,00€
    100g
    1.883,00€
  • 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate

    CAS:
    3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is an antiviral and anticancer agent that is used for the synthesis of DNA and RNA. It is a novel nucleoside analog that has been modified to be activated by phosphoramidite chemistry. 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is synthesized from 2,6-diisopropylaniline, methyl 3-(aminomethyl)-1H-pyrrole-2,4-dicarboxylate, and propylamine in cyclohexane at reflux.
    Formula:C13H22N3O14P3
    Purezza:Min. 95%
    Peso molecolare:537.25 g/mol

    Ref: 3D-NP145591

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  • 5-Azacytidine

    CAS:
    <p>An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.</p>
    Formula:C8H12N4O5
    Purezza:Min. 95%
    Colore e forma:White Off-White Powder
    Peso molecolare:244.21 g/mol

    Ref: 3D-NA02947

    10g
    314,00€
    25g
    471,00€
    50g
    629,00€
    100g
    993,00€
    250g
    1.403,00€
  • 2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite

    CAS:
    2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleotide analog. It is an anticancer drug that inhibits DNA synthesis and can be used to treat cancer. The 2'-deoxy-N6-DMF moiety has been shown to inhibit the activity of DNA polymerase and other enzymes involved in DNA replication. This compound also has a novel mechanism of action that is not present in any other known anticancer drugs. CAS No. 195375-66-7.br>br>2'-Deoxy-N6-DMF 5'-O-MMT adenosine 3'-cephosphoramidite is often used as a building block for oligonucleotide synthesis because it is resistant to the removal of phosphate groups by alkaline phosphatases. The lack of phosphate groups makes this compound more stable than standard nucleotides
    Formula:C42H51N8O5P
    Purezza:Min. 95%
    Peso molecolare:778.9 g/mol

    Ref: 3D-PD09131

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  • N4-Propanoylcytidine

    CAS:
    <p>N4-Propanoylcytidine is a modified nucleoside which can be used as an antiviral agent, anticancer agent and activator. It activates the immune system by stimulating the production of interferon, resulting in the inhibition of viral replication. N4-Propanoylcytidine has also been shown to inhibit the proliferation of cancer cells and induce apoptosis. This compound has a novel chemical structure that is not found in natural nucleosides.</p>
    Purezza:Min. 95%

    Ref: 3D-NP162885

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  • Dihydrozeatin riboside

    CAS:
    <p>Dihydrozeatin riboside is a cytokinin, a group of plant hormones that regulate various aspects of plant growth and development. It is found in the form of an ester, dihydrozeatin riboside, which is produced by the action of trifluoroacetic acid on zeatin. The natural function of this hormone is to stimulate cell division in plants, but it has also been shown to have antibacterial effects against bacterial strains such as Bacillus subtilis and Escherichia coli. Dihydrozeatin riboside inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction</p>
    Formula:C15H23N5O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:353.37 g/mol

    Ref: 3D-ND30220

    25mg
    225,00€
    50mg
    352,00€
    100mg
    471,00€
    250mg
    889,00€
  • 4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D- ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine


    4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a synthetic activator that selectively activates the transcription of genes in cells. It has been shown to have anticancer activity and may be useful as a therapeutic agent for the treatment of certain cancers. 4C 7 (2dEB 3,5BT) 5I is also known to be an antiviral agent against HIV and influenza virus. The modification on the 2'-deoxyribose sugar moiety can enhance both activation and antiviral activities.
    Purezza:Min. 95%

    Ref: 3D-NC162932

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  • Guanosine 5'-triphosphate sodium salt hydrate

    CAS:
    <p>Guanosine 5'-triphosphate sodium salt hydrate (GTP) is an energy-rich nucleotide that is synthesized from guanosine and inorganic phosphate. GTP acts as a coenzyme in the synthesis of proteins, lipids, and other biological molecules. It also has been shown to inhibit the growth of murine sarcoma virus by regulating intracellular calcium levels. GTP's binding to a receptor on the surface of cells leads to a cascade of reactions that ultimately lead to the production of proteins. This process can be inhibited by pharmacological agents such as thiostrepton, which blocks GTP's incorporation into proteins.</p>
    Formula:C10H16N5O14P3•Nax•(H2O)x
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:523.18 g/mol

    Ref: 3D-NG30609

    1g
    1.253,00€
    50mg
    269,00€
    100mg
    419,00€
    250mg
    555,00€
    500mg
    843,00€
  • 5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt

    CAS:
    5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.
    Formula:C9H12BrN2O8PNa2
    Purezza:Min. 97 Area-%
    Colore e forma:Powder
    Peso molecolare:433.06 g/mol

    Ref: 3D-NB09916

    1g
    838,00€
    2g
    1.472,00€
    5g
    3.325,00€
    250mg
    336,00€
    500mg
    508,00€
  • 2',3'-Dideoxyinosine

    CAS:
    <p>2',3'-Dideoxyinosine is a purine analog that can suppress human immunodeficiency virus (HIV) replication after intracellular metabolic conversion</p>
    Formula:C10H12N4O3
    Purezza:Min. 95 Area-%
    Colore e forma:White Off-White Powder
    Peso molecolare:236.23 g/mol

    Ref: 3D-ND02929

    5g
    305,00€
    10g
    496,00€
    25g
    965,00€
  • 6-Methylmercapto-9-(b-D-ribofuranosyl)purine

    CAS:
    6-Methylmercapto-9-(b-D-ribofuranosyl)purine (6MMPR) is a nucleotide analog that is synthesized through the process of ribosylation. It has been shown to be reactive and inflammatory in the colon, which may be due to its role as an enzyme inhibitor. 6MMPR inhibits target enzymes such as 2-methylthio-6-chloropurine riboside, which are involved in DNA synthesis and repair. This drug also has anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory cytokines by activated immune cells. 6MMPR is used for the treatment of bowel diseases such as Crohn's disease and ulcerative colitis.
    Formula:C11H14N4O4S
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:298.32 g/mol

    Ref: 3D-NM06304

    250mg
    348,00€
    500mg
    464,00€
  • 2-Iodoadenosine

    CAS:
    <p>2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.</p>
    Formula:C10H12IN5O4
    Purezza:Min. 97 Area-%
    Colore e forma:Powder
    Peso molecolare:393.14 g/mol

    Ref: 3D-NI04749

    1g
    430,00€
    2g
    598,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    250,00€
  • 6-Thioinosine 5'-monophosphate

    CAS:
    <p>6-Thioinosine 5'-monophosphate (6TIMP) is a hydrogen bond donor that possesses inhibitory properties against protein synthesis. It has been shown to have an anti-inflammatory effect and can be used for the treatment of inflammatory bowel disease. 6TIMP is also able to inhibit the bcr-abl kinase, which is implicated in the development of renal cell cancer. 6TIMP can be administered intravenously or orally and penetrates tissues well. The rate at which it enters cells is dependent on the transport rate, which is determined by its acidity. 6TIMP has been shown to cause DNA damage, leading to apoptosis and cell death in carcinoma cell lines. The mechanism of action appears to involve inhibition of cellular protein synthesis, acid formation, and DNA damage.</p>
    Formula:C10H13N4O7PS
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:364.27 g/mol

    Ref: 3D-NT10843

    1mg
    307,00€
    2mg
    454,00€
    5mg
    1.002,00€
    10mg
    1.759,00€
    25mg
    3.969,00€
  • 2'-Deoxy-6-thioguanosine-5'-monophosphate

    CAS:
    Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.
    Formula:C10H14N5O6PS
    Purezza:Min. 95%
    Peso molecolare:363.29 g/mol

    Ref: 3D-ND159697

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  • N4-Benzoyl-5'-O-Trityl-cytidine

    CAS:
    <p>N4-Benzoyl-5'-O-Trityl-cytidine (NBT) is a nucleoside that occurs in two forms: diphosphate and monophosphate. It is used as an activator of DNA and RNA synthesis, and as an antiviral agent. NBT has been shown to inhibit the replication of herpes simplex virus type 1, vaccinia virus and influenza virus in cell culture. It also inhibits the reverse transcriptase activity of HIV in vitro.<br>NBT is a novel deoxyribonucleoside phosphoramidite, which can be used in the synthesis of oligodeoxyribonucleotides for use in DNA sequencing or gene cloning applications.</p>
    Formula:C35H31N3O6
    Purezza:Min. 95%
    Peso molecolare:589.64 g/mol

    Ref: 3D-NB57524

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  • Acetyl hypoxanthine

    CAS:
    <p>Acetyl hypoxanthine is an inorganic compound that has a cyclophosphate group. It can be synthesized from the reaction of acetic acid and 6-chloropurine, which is activated with trifluoroacetic acid and irradiated with ultraviolet light. Acetyl hypoxanthine can then be synthesized by ammonolysis of chloroacetone using ammonia or by chlorinating acetylene with chlorine. The advantages of this compound are its high yield and low cost.</p>
    Formula:C7H6N4O2
    Purezza:Min. 95 Area-%
    Colore e forma:Powder
    Peso molecolare:178.15 g/mol

    Ref: 3D-NA158227

    25mg
    594,00€
    50mg
    724,00€
    100mg
    965,00€
  • 8-Hydroxyadenosine

    CAS:
    <p>8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.</p>
    Formula:C10H13N5O5
    Purezza:Min. 98 Area-%
    Colore e forma:Powder
    Peso molecolare:283.25 g/mol

    Ref: 3D-NH08494

    1g
    883,00€
    2g
    1.494,00€
    100mg
    255,00€
    250mg
    477,00€
    500mg
    639,00€
  • 5'-O-p-Anisoyl-2'-deoxyuridine


    <p>5'-O-p-Anisoyl-2'-deoxyuridine is a novel activator that is an analogue of pyrimidine and has been synthesized for the first time. It belongs to the group of nucleosides and has been modified chemically. This compound can be used as a pharmaceutical drug for the treatment of cancer or viral infections.</p>
    Formula:C17H18N2O7
    Purezza:Min. 95%
    Peso molecolare:362.33 g/mol

    Ref: 3D-NA08690

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  • 6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine

    CAS:
    <p>6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is a modified monophosphate analog of adenosine. It is an antiviral agent that inhibits the synthesis of nucleic acids in virus-infected cells, preventing viral replication and spread. 6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is also used as a radiosensitizer to treat cancer. This drug is synthesized by high purity, high quality and reliable suppliers.</p>
    Formula:C14H19N5O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:337.33 g/mol

    Ref: 3D-NM163017

    25mg
    382,00€
    50mg
    595,00€
    100mg
    965,00€
  • TFA-aa-dUPhosphoramidite


    TFA-aa-dUPhosphoramidite is a high quality, novel DNA phosphoramidite. It is used for the synthesis of deoxyribonucleosides and ribonucleosides. TFA-aa-dUPhosphoramidite has been shown to be an activator in the synthesis of RNA and DNA, and it is also resistant to degradation by nucleases. This product has CAS No.
    Formula:C44H51N5O9P
    Purezza:Min. 95%
    Peso molecolare:824.88 g/mol

    Ref: 3D-PT57505

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  • 9-(β-D-Xylofuranosyl)adenine

    CAS:
    <p>9-(β-D-Xylofuranosyl)adenine is a nucleoside analog that inhibits the activity of adenine nucleotide. It has been shown to be effective against a wide range of viruses and bacteria, including HIV, herpes simplex virus, influenza A virus, and Mycobacterium tuberculosis. The chemical structure of 9-(β-D-Xylofuranosyl)adenine resembles that of adenosine and this similarity confers inhibitory properties on it. 9-(β-D-Xylofuranosyl)adenine is an analog of adenosine. The steric interactions between the intramolecular hydrogen bonds in 9-(β-D-Xylofuranosyl)adenine are weaker than those in adenosine, which allows it to bind more easily with the enzyme responsible for the conversion of adenosine to inosinic acid. This inhibition prevents the formation of ATP from AMP, leading</p>
    Formula:C10H13N5O4
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:267.24 g/mol

    Ref: 3D-FX144729

    25mg
    194,00€
    50mg
    337,00€
    100mg
    549,00€
    250mg
    1.155,00€
    500mg
    2.110,00€
  • 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine

    CAS:
    <p>Please enquire for more information about 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C13H15BrN2O7
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:391.18 g/mol

    Ref: 3D-ND04658

    1g
    148,00€
  • 3’-O-tert-butyldimethylsilyl-5’-O-DMT-N1-methylpseudouridine

    CAS:
    <p>3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1-methylpseudouridine is a synthetic nucleoside that is used in the synthesis of deoxyribonucleosides. It is an activator nucleoside that has antiviral activity and provides high purity, novel monophosphate nucleosides, and modified nucleosides. 3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1 methylpseudouridine has CAS No. 875302–43–5 and can be used for the synthesis of phosphoramidites or ribonucleotides.</p>
    Purezza:Min. 95%

    Ref: 3D-NB162907

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  • 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine

    CAS:
    <p>5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine is an analogue of adenosine that has inhibitory activities on the biosynthetic pathway of polyamines. It has been shown to have a cytostatic effect on murine leukemia cells in vitro. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine inhibits the production of polyamines by interfering with the enzyme responsible for their biosynthesis, ornithine decarboxylase. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine also inhibits the growth of murine leukemia cells and other leukemia cell lines, including L1210 and MM1.</p>
    Formula:C11H14FN5O3S
    Purezza:Min. 95%
    Peso molecolare:315.33 g/mol

    Ref: 3D-ND87794

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  • N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine

    CAS:
    N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is a nucleoside monophosphate that is used in the treatment of HIV infection. The antiviral activity of N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is due to its ability to inhibit viral DNA synthesis by competing with natural substrates for incorporation into the growing chain. This compound also inhibits cancer cell proliferation and may be useful in the treatment of other forms of cancer. N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is synthesized from 2,4,6,-trichlorophenylpiperazine (TCPP) and cyanogen bromide in a two step process using phosphoramidites.
    Formula:C23H21N3O6
    Purezza:Min. 95%
    Peso molecolare:435.44 g/mol

    Ref: 3D-NB08667

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  • N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine


    <p>N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine is a modified nucleoside that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This nucleoside inhibits viral replication and prevents the production of new viruses in cells infected by HIV. N4-Benzoyl-2’,3’-di-O -tert -butyldimethylsilyl -5’ -O -DMT -N4 methylcytidine also inhibits DNA synthesis by inhibiting the activity of DNA polymerases.<br>This drug has been shown to be effective against cancer cells and may have anticancer properties.</p>
    Purezza:Min. 95%

    Ref: 3D-NB162891

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  • 2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

    CAS:
    <p>2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a modified purine nucleoside, protected with acetyl groups, which protect the sugar during chemical reactions. This compound is based on a purine ring and also contains an acetamido group at position 2, a chlorine atom at position 6 and a β-D-ribofuranosyl sugar.</p>
    Formula:C18H20ClN5O8
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:469.83 g/mol

    Ref: 3D-NA04442

    1g
    1.334,00€
    2g
    2.369,00€
    100mg
    239,00€
    250mg
    454,00€
    500mg
    781,00€
  • 2’C-Methyl-5-methoxyuridine

    CAS:
    <p>2’-C-Methyl-5-methoxyuridine is a nucleoside analog that inhibits viral replication by inhibiting DNA synthesis. It is also used in the treatment of cancer, as it inhibits the growth of tumor cells by altering their genetic material. This drug is a phosphorothioate and can be activated with an activator to form its active form, which is incorporated into DNA during replication. 2’-C-Methyl-5-methoxyuridine has been shown to be effective against many viruses, including human immunodeficiency virus (HIV), herpes simplex virus type 1 (HSV1), and herpes simplex virus type 2 (HSV2). This drug has been shown to cause death of tumor cells via apoptosis or cell cycle arrest at the G0/G1 phase.</p>
    Purezza:Min. 95%

    Ref: 3D-NM162878

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  • 2'-C-Methyl-6-S-methyl-6-thioinosine

    CAS:
    <p>2'-C-Methyl-6-S-methyl-6-thioinosine is a modified nucleoside that can be used as an antiviral and anticancer agent. It has been shown to activate the immune system by inducing cytokine production, which leads to increased cytotoxicity against tumor cells. 2'-C-Methyl-6-S-methyl-6-thioinosine has also been shown to inhibit DNA synthesis and induce apoptosis in cancer cells. This product is of high purity and quality, with a CAS number of 172722-76-8.</p>
    Purezza:Min. 95%

    Ref: 3D-NM14097

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  • N6-Benzoyl-8-hydroxy-2'-O-methyladenosine


    <p>N6-Benzoyl-8-hydroxy-2'-O-methyladenosine is a nucleoside analogue that inhibits the replication of RNA and DNA. It is a monophosphate, which can be converted to a diphosphate through phosphorylation. N6-Benzoyl-8-hydroxy-2'-O-methyladenosine has been shown to inhibit cancer cells and may have potential for use in antiviral therapy. This compound was synthesized from 2,4,5,6 tetrahydrobenzyl alcohol and 2'-deoxyadenosine. The CAS number for this compound is 79430-89-1.</p>
    Purezza:Min. 95%

    Ref: 3D-NB145742

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  • 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine

    CAS:
    <p>5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine is a novel nucleoside that has antiviral and anticancer properties. It is an activator of the monophosphate phosphoramidites and has been shown to inhibit the growth of cancer cells in vitro. 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine is also able to inhibit viral replication by terminating cellular DNA synthesis at the level of RNA polymerase II. This results in the synthesis of defective viral genomes that are unable to produce new viruses, thereby preventing viral spread.</p>
    Formula:C19H19FN2O7
    Purezza:Min. 95%
    Peso molecolare:406.36 g/mol

    Ref: 3D-NT144914

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