Sistema complementare
Il sistema del complemento è una parte cruciale della risposta immunitaria, costituito da una serie di piccole proteine che migliorano la capacità degli anticorpi e delle cellule fagocitiche di eliminare i patogeni da un organismo. Queste proteine lavorano insieme per opsonizzare i patogeni, indurre risposte infiammatorie e lisare direttamente le membrane dei patogeni, giocando un ruolo vitale nell'immunità innata e nella funzione immunitaria globale. Da CymitQuimica, offriamo proteine del sistema del complemento di alta qualità per supportare i vostri studi immunologici e la ricerca clinica.
Trovati 191 prodotti per "Sistema complementare".
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L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Formula:C38H64N8O13Colore e forma:SolidPeso molecolare:840.973C3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Formula:C37H62F3N13O12Purezza:99.92%Colore e forma:White SolidPeso molecolare:937.96Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formula:C128H190N24O33Colore e forma:SolidPeso molecolare:2593.02PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formula:C47H65N11O7Purezza:98%Colore e forma:SolidPeso molecolare:896.09PIC1 PA
CAS:PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Formula:C71H123N19O21S2Colore e forma:SolidPeso molecolare:1642.98TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formula:C107H170N40O26Purezza:98%Colore e forma:SolidPeso molecolare:2432.75AMY-101 TFA
CAS:AMY-101 TFA is an inhibitor of complement C3 and an immunomodulator, gingivitis and periodontitis. reduces inflammation and lowers levels of MMP-8 and MMP-9Formula:C85H118F3N23O20S2Purezza:98.79% - 99.99%Colore e forma:SolidPeso molecolare:1903.11Izastobart
CAS:Izastobart is an antagonistic monoclonal antibody targeting complement component 5a receptor 1 (C5aR1/CD88). Izastobart binds the N-terminus of C5aR1 and blocks the interaction between C5a and C5aR1, inhibiting receptor-mediated cell activation and migration. Izastobart is used for research on C5aR1-mediated complement signaling, immune regulation, and the tumor immune microenvironment.Purezza:95%Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Formula:(C2H4O)nC170H248N50O47S4·xC2H4O2Purezza:97.10%Colore e forma:Odour SolidPeso molecolare:1501.7Complement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFormula:C22H20F2N6OPurezza:97.77% - >99.99%Colore e forma:Yellow SolidPeso molecolare:422.43Complement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Colore e forma:Lyophilized PowderPeso molecolare:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Colore e forma:Lyophilized PowderPeso molecolare:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.MASP2 Protein, Human, Recombinant (His)
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.Colore e forma:Lyophilized PowderPeso molecolare:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.Complement C3a Protein, Mouse, Recombinant
Complement C3a Protein, Mouse, Recombinant is expressed in E.Purezza:Greater than 95% as determined by reducing SDS-PAGE - Greater than 95% as determined by reducing SDS-PAGE. (QC verified)Colore e forma:Lyophilized PowderPeso molecolare:9 KDa (reducing condition)Complement Factor MASP3 Protein, Human, Recombinant (His)
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.Colore e forma:Lyophilized PowderPeso molecolare:31.10 kDa (predicted); 43-53 kDa (due to glycosylation)Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Colore e forma:Lyophilized PowderPeso molecolare:25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.C1QBP Protein, Mouse, Recombinant (His)
C1QBP Protein, Mouse, Recombinant (His) is expressed in E.Colore e forma:Lyophilized PowderPeso molecolare:24.7 kDa (predicted); 32 kDa (reducing conditions)MASP2 Protein, Rat, Recombinant (E. coli, His)
MASP2 Protein, Rat, Recombinant (E.Purezza:> 95% as determined by Tris-Bis PAGE - > 95% as determined by Tris-Bis PAGEColore e forma:Lyophilized PowderPeso molecolare:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.C1s Protein, Human, Recombinant (His)
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.Colore e forma:Lyophilized PowderPeso molecolare:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)
Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His) is expressed in HEK293 Cells. The accession number is P01027-1.Colore e forma:Lyophilized PowderPeso molecolare:187.86 kDa (Predicted); 65-68 kDa, 110-115 kDa and 165-180 kDa (Due to glycosylation)
