Sistema complementare
Il sistema del complemento è una parte cruciale della risposta immunitaria, costituito da una serie di piccole proteine che migliorano la capacità degli anticorpi e delle cellule fagocitiche di eliminare i patogeni da un organismo. Queste proteine lavorano insieme per opsonizzare i patogeni, indurre risposte infiammatorie e lisare direttamente le membrane dei patogeni, giocando un ruolo vitale nell'immunità innata e nella funzione immunitaria globale. Da CymitQuimica, offriamo proteine del sistema del complemento di alta qualità per supportare i vostri studi immunologici e la ricerca clinica.
Trovati 179 prodotti di "Sistema complementare"
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PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formula:C71H123N19O21S2·xC2HF3O2Colore e forma:SolidASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Colore e forma:Odour LiquidJPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formula:C49H63FN10O9Colore e forma:SolidPeso molecolare:955.08CK3 peptide
CAS:CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.
Formula:C40H72N12O12S2Colore e forma:SolidPeso molecolare:977.203BCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Formula:C14H11ClN2O2S2Purezza:99.71%Colore e forma:SoildPeso molecolare:338.83Vensobafusp alfa
CAS:Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Colore e forma:LiquidFactor B-IN-1
CAS:Factor B-IN-1 is a Factor B inhibitor.Formula:C19H16N4O2Colore e forma:SolidPeso molecolare:332.3559PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formula:C47H65N11O7Purezza:98%Colore e forma:SolidPeso molecolare:896.09Human Immunoglobulin M
Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.Colore e forma:Odour SolidBM213
CAS:BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Formula:C43H70N12O10Purezza:98%Colore e forma:SoildPeso molecolare:915.09C2 Protein (human)
C2 Protein (human) is a naturally glycosylated peptide with a 20-amino acid signal sequence. It plays a critical regulatory role in the early activation stages of the classical pathway and is involved in the formation of the classical pathway C3 convertase, C4b2a.Colore e forma:Odour SolidCampneoside II
CAS:Campneoside II, a compound extracted from the wood of Paulownia tomentosa var. tomentosa, demonstrates remarkable anti-complement activity [1].Formula:C29H36O16Colore e forma:SolidPeso molecolare:640.59PIC1 PA
CAS:PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Formula:C71H123N19O21S2Colore e forma:SolidPeso molecolare:1642.98C1q Protein (rat)
C1qProtein (Rat) is a subunit of the complement system. It can recognize various ligands and plays a role in maintaining immune system balance, promoting tissue repair, and defending against pathogens.Colore e forma:Odour SolidZilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formula:C128H190N24O33Colore e forma:SolidPeso molecolare:2593.02Claseprubart
CAS:Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.Colore e forma:LiquidC3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Formula:C37H62F3N13O12Purezza:99.92%Colore e forma:SolidPeso molecolare:937.96C3 Protein (human)
C3 Protein (human) is an intrinsically glycosylated polypeptide composed of two disulfide-linked chains. Complement protein C3 is a pivotal molecule within the complement system, and its activation is fundamental to all essential functions of this system.Colore e forma:Odour SolidC1q Protein (Rabbit)
C1qProtein (Rabbit) is a subunit of the complement system. It recognizes various ligands, playing a role in maintaining immune system balance, promoting tissue repair, and defending against pathogens.Colore e forma:Odour SolidC5aR2 agonist P32 acetate
C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.Formula:C54H70N16O11·xC2H4O2Colore e forma:SolidPeso molecolare:1119.23 (free base)
