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Sistema complementare

Sistema complementare

Il sistema del complemento è una parte cruciale della risposta immunitaria, costituito da una serie di piccole proteine che migliorano la capacità degli anticorpi e delle cellule fagocitiche di eliminare i patogeni da un organismo. Queste proteine lavorano insieme per opsonizzare i patogeni, indurre risposte infiammatorie e lisare direttamente le membrane dei patogeni, giocando un ruolo vitale nell'immunità innata e nella funzione immunitaria globale. Da CymitQuimica, offriamo proteine del sistema del complemento di alta qualità per supportare i vostri studi immunologici e la ricerca clinica.

Trovati 156 prodotti di "Sistema complementare"

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  • PIC1 PA TFA


    <p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>
    Formula:C71H123N19O21S2·xC2HF3O2
    Colore e forma:Solid
  • Compstatin TFA


    <p>Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).</p>
    Formula:C68H100F3N23O19S2
    Colore e forma:Solid
    Peso molecolare:1664.79
  • PMX 205

    CAS:
    <p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>
    Formula:C45H62N10O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:839.04
  • Claseprubart

    CAS:
    <p>Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.</p>
    Colore e forma:Liquid
  • AMY-101 TFA

    CAS:
    <p>AMY-101 TFA is an inhibitor of complement C3 and an immunomodulator, gingivitis and periodontitis. reduces inflammation and lowers levels of MMP-8 and MMP-9</p>
    Formula:C85H118F3N23O20S2
    Colore e forma:Solid
    Peso molecolare:1903.11
  • NH2-C6-ARC186


    <p>NH2-C6-ARC186 is a derivative of the aptamer ARC186, featuring an NH2-C6 moiety that enables coupling to various peptides or molecules.</p>
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:12881
  • JPE-1375

    CAS:
    <p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>
    Formula:C49H63FN10O9
    Colore e forma:Solid
    Peso molecolare:955.08
  • Olendalizumab

    CAS:
    <p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>
    Colore e forma:Liquid
  • PMX-53

    CAS:
    <p>PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions &amp; metastasis in mice; blocks rat hypernociception.</p>
    Formula:C47H65N11O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:896.09
  • Zilucoplan (PEG2)


    <p>Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).</p>
    Formula:C128H190N24O33
    Colore e forma:Solid
    Peso molecolare:2593.02
  • Human Immunoglobulin M


    <p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>
    Colore e forma:Odour Solid
  • PMX 205 Trifluoroacetate


    <p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>
    Formula:C47H63F3N10O8
    Colore e forma:Solid
    Peso molecolare:953.06
  • Certepetide

    CAS:
    <p>Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.</p>
    Formula:C37H60N14O14S2
    Colore e forma:Solid
    Peso molecolare:989.09
  • Vemircopan

    CAS:
    <p>Vemircopan is a complement factor D inhibitor.</p>
    Formula:C29H28BrN7O3
    Colore e forma:Solid
    Peso molecolare:602.493
  • L-156,602

    CAS:
    <p>L-156,602 has a wide range of applications in life science related research.</p>
    Formula:C38H64N8O13
    Colore e forma:Solid
    Peso molecolare:840.973
  • Factor B-IN-1

    CAS:
    <p>Factor B-IN-1 is a Factor B inhibitor.</p>
    Formula:C19H16N4O2
    Colore e forma:Solid
    Peso molecolare:332.3559
  • Pegcetacoplan acetate


    <p>Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.</p>
    Colore e forma:Odour Solid
  • TLQP-21

    CAS:
    <p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>
    Formula:C107H170N40O26
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2432.75
  • AMY-101

    CAS:
    <p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>
    Formula:C83H117N23O18S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1789.11
  • tLyP-1 peptide

    CAS:
    <p>tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.</p>
    Formula:C31H59N15O10S
    Colore e forma:Solid
    Peso molecolare:833.96