Sistema complementare
Il sistema del complemento è una parte cruciale della risposta immunitaria, costituito da una serie di piccole proteine che migliorano la capacità degli anticorpi e delle cellule fagocitiche di eliminare i patogeni da un organismo. Queste proteine lavorano insieme per opsonizzare i patogeni, indurre risposte infiammatorie e lisare direttamente le membrane dei patogeni, giocando un ruolo vitale nell'immunità innata e nella funzione immunitaria globale. Da CymitQuimica, offriamo proteine del sistema del complemento di alta qualità per supportare i vostri studi immunologici e la ricerca clinica.
Trovati 191 prodotti per "Sistema complementare".
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Riliprubart
CAS:Riliprubart (SAR445088) is a humanised monoclonal antibody targeting C1s, applicable for neurological disorders such as CIDP, which inhibits activated C1s in the classical complement pathway.Purezza:98.0% (SDS-PAGE); 99.0% (SEC-HPLC) - 98.0% (SDS-PAGE); 99.0% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.52 kDa (Predicted)Avacincaptad pegol sodium
CAS:Avacincaptad pegol (ARC1905) is an anti-C5 aptamer for AMD study, inhibiting C5 cleavage.Colore e forma:SolidPeso molecolare:53500Anti-Mouse CD11b Antibody (DC13)
Anti-Mouse CD11b Antibody (DC13) is a monoclonal antibody targeting mouse CD11b for immunological research.Peso molecolare:~150 kDaTanruprubart
CAS:Tanruprubart, Humanized anti-C1q mAb, classical complement pathway target, prevents neuroinflammation, for Guillain-Barré syndrome (GBS) studies.Purezza:98.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 98.1% (SDS-PAGE); 96.4% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.51 kDa (Predicted)Anti-Mouse CD11b Antibody (M1/70)
Anti-Mouse CD11b Antibody (M1/70) inhibits cell adhesion, kills cancer cells and alleviates fibrosis and inflammation.Purezza:95% - 98.1% (SDS-PAGE); 99.8% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:147.31 kDa (Predicted)Anti-Human CD11a Antibody (MHM24)
Anti-Human CD11a Antibody (MHM24), inhibitory antibody， recognizes both high-affinity and low-affinity conformational forms of the antigen.Purezza:95%Peso molecolare:~150 kDaGefurulimab
CAS:Gefurulimab (ALXN-1720) is a bispecific antibody derived from humans, targeting complement C5 and albumin.Colore e forma:LiquidCrovalimab
CAS:Crovalimab (SKY59; RO7112689) is an humanised monoclonal antibody that binds to complement C5 , paroxysmal nocturnal haemoglobinuria (PNH).Purezza:95%Colore e forma:Transparent LiquidPeso molecolare:~150 kDaEmpasiprubart
CAS:Empasiprubart (anti-C2 mAb) inhibits classical & lectin complement pathways upstream of C3, showing efficacy in autoimmune models.Purezza:95%Colore e forma:LiquidPeso molecolare:~150 kDaAnti-Human/Mouse CD11c Antibody (N418)
Anti-Human/Mouse CD11c Antibody (N418) specifically recognizes mouse CD11c. CD11c forms a heterodimer with CD18 and plays a key role in leukocyte adhesion.Purezza:95%Peso molecolare:146.92 kDa (Predicted)Rovelizumab
CAS:Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Purezza:95.7% (SDS-PAGE); 99.0% (SEC-HPLC) - 95.7% (SDS-PAGE); 99.0% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.96 kDa (Predicted)NGM-621
NGM-621 is a CHO-expressed fully human monoclonal antibody targeting Complement C3, composed of a huIgG1 heavy chain and huκ light chain with a predicted molecular weight of 149.04 kDa. NGM-621 is used as a precise biological reagent for investigating complement-mediated inflammation and immune regulation mechanisms.Purezza:95% - 98.1% (SDS-PAGE); 96.4% (SEC-HPLC)Peso molecolare:144.78 kDa (Predicted)Vensobafusp alfa
CAS:Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Colore e forma:LiquidComplement C8 γ Protein, Human, Recombinant (His)
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.Colore e forma:Lyophilized PowderPeso molecolare:22 KDa (reducing condition)Ref: TM-TMPJ-00585
10µg120,00€20µg185,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€MBL2 Protein, Human, Recombinant (His)
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.Purezza:> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Colore e forma:Lyophilized PowderPeso molecolare:31 KDa (reducing condition)Ref: TM-TMPJ-00136
5µg62,00€10µg100,00€20µg138,00€50µg244,00€100µg436,00€200µg782,00€500µg1.710,00€1mg2.457,00€Greziprubart
CAS:Greziprubart (STSA-1002) is a fully human monoclonal antibody that targets human C5a(KD 1.05×10⁻¹⁰ M), acute respiratory distress syndrome (ARDS)Colore e forma:Odour LiquidPeso molecolare:~148 kDaClaseprubart
CAS:Claseprubart is an anti-C1s monoclonal antibody that inhibits complement activation and may support research on complement-mediated autoimmunity and inflammation.Purezza:95%Colore e forma:LiquidPeso molecolare:~148 kDaAnti-Mouse CD11b Antibody (5C6)
Anti-Mouse CD11b Antibody (5C6) inhibits myelomonocytic cell adhesion and inflammatory cell recruitment.Purezza:95% - 97.7% (SDS-PAGE); 99.4% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.68 kDa (Predicted)Erlizumab
CAS:Erlizumab is a humanized anti-CD18 mAb that reduces inflammation and reperfusion injury by blocking leukocyte adhesion.Purezza:95%Peso molecolare:98.57 kDa (Predicted)MEDI7814
MEDI7814 is a humanized monoclonal antibody inhibitor targeting C5a and C5adesArg. It has binding affinities of 14 pM for recombinant human C5a and 8 pM for serum-purified human C5a. MEDI7814 shows potential for treating acute inflammatory conditions, including sepsis and renal ischemia-reperfusion injury.
