Sistema complementare
Il sistema del complemento è una parte cruciale della risposta immunitaria, costituito da una serie di piccole proteine che migliorano la capacità degli anticorpi e delle cellule fagocitiche di eliminare i patogeni da un organismo. Queste proteine lavorano insieme per opsonizzare i patogeni, indurre risposte infiammatorie e lisare direttamente le membrane dei patogeni, giocando un ruolo vitale nell'immunità innata e nella funzione immunitaria globale. Da CymitQuimica, offriamo proteine del sistema del complemento di alta qualità per supportare i vostri studi immunologici e la ricerca clinica.
Trovati 191 prodotti per "Sistema complementare".
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Anti-Human GC1q R/C1QBP Antibody (60.11)
Anti-GC1q R/C1QBP Antibody (60.11) is a mouse IgG1, κ chimeric antibody designed to target human GC1q R/C1QBP. The recommended isotype control for this antibody is Mouse IgG1 kappa, Isotype Control.Colore e forma:Odour LiquidC5aR-IN-2
CAS:C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Formula:C36H40FN5O2Colore e forma:SolidPeso molecolare:593.73BCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Formula:C14H10N2O2S2Purezza:98%Colore e forma:SolidPeso molecolare:302.37Anti-Human Complement Factor B Antibody
Anti-Complement Factor B Antibody is a potent inhibitory antibody targeting complement factor B. Anti-Complement Factor B Antibody demonstrates the capacity to suppress complement-mediated inflammatory responses and provides essential utility for researching alternative pathway-driven immune disorders.Peso molecolare:145.59 kDa (Predicted)NRP1 antagonist 2
CAS:NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Formula:C20H17ClN6OS2Colore e forma:SolidPeso molecolare:456.97FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Formula:C23H23NO4Purezza:98.85%Colore e forma:White SolidPeso molecolare:377.433Isocyclosporin A
CAS:Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Formula:C62H111N11O12Colore e forma:SolidPeso molecolare:1202.6112ASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Colore e forma:Odour LiquidC1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formula:C16H22Cl3N5Colore e forma:SolidPeso molecolare:390.738NDT 9513727
CAS:NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Formula:C36H35N3O4Purezza:99.16%Colore e forma:SolidPeso molecolare:573.68Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Formula:C24H32N2O6Purezza:98.27%Colore e forma:White SolidPeso molecolare:444.5207Ref: TM-T10863
1mg75,00€5mg145,00€1mL*10mM (DMSO)159,00€10mg195,00€25mg312,00€50mg439,00€100mg628,00€EG00229
CAS:EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.Formula:C19H20F3N7O7S3Purezza:98.23%Colore e forma:SolidPeso molecolare:611.595Ref: TM-T11153
1mg45,00€5mg103,00€1mL*10mM (DMSO)133,00€10mg148,00€25mg238,00€50mg352,00€100mg524,00€200mg749,00€C3a Receptor Agonist
CAS:C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.Formula:C27H35N3O2Purezza:99.76%Colore e forma:SolidPeso molecolare:433.5857Factor D inhibitor 6
CAS:Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.Formula:C23H22ClFN6O3Colore e forma:SolidPeso molecolare:484.911C5aR-IN-1
CAS:C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.Formula:C36H39F4N3O2Colore e forma:SolidPeso molecolare:621.71EG01377
CAS:EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.Formula:C26H30N6O6S2Purezza:98%Colore e forma:SolidPeso molecolare:586.68Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Formula:C29H28BrN7O3Colore e forma:SolidPeso molecolare:602.482W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formula:C30H37ClN2O2Purezza:96.8%Colore e forma:White SolidPeso molecolare:493.08Ref: TM-T17250
1mg79,00€5mg120,00€1mL*10mM (DMSO)132,00€10mg184,00€25mg304,00€50mg491,00€100mg708,00€200mg963,00€Factor B-IN-2
CAS:Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.Formula:C25H32N2O4Colore e forma:SolidPeso molecolare:424.53Iptacopan
CAS:Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.Formula:C25H30N2O4Purezza:98.87% - >99.99%Colore e forma:SolidPeso molecolare:422.5167Ref: TM-T11864
1mg56,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg184,00€25mg333,00€50mg557,00€100mg918,00€200mg1.242,00€
