Chetoni e Derivati
I chetoni sono composti organici che contengono un gruppo carbonilico (C=O) legato a due atomi di carbonio, formando una struttura in cui il gruppo carbonilico è affiancato da gruppi alchilici o arilici. In farmacologia, i chetoni sono utilizzati nella formulazione di API grazie alla loro capacità di migliorare la solubilità e la stabilità dei principi attivi. Alcuni chetoni possiedono proprietà antinfiammatorie, analgesiche e antimicrobiche. I derivati dei chetoni includono composti in cui il gruppo carbonilico è modificato, come gli enoli, che trovano applicazione nella sintesi di farmaci e come intermedi chimici nella produzione di altri composti bioattivi. I derivati dei chetoni sono impiegati nella progettazione di nuovi farmaci, inclusi quelli per il trattamento di malattie neurodegenerative, disturbi metabolici e alcuni tipi di cancro, grazie ai loro effetti specifici sugli enzimi e sui processi cellulari.
Trovati 2394 prodotti di "Chetoni e Derivati"
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5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-M-6831
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-M-68109
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-M-6811
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-M-68114
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-P-264002
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-A-026
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-C-249009
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaFlupirtine maleate
CAS:<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Formula:C15H17FN4O2·C4H4O4Purezza:99.5% - 99.9%Colore e forma:Off-White Crystalline PowderPeso molecolare:420.39Ref: 4Z-K-0343
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-M-6851
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-T-0641
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-M-105010
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-F-3322
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-A-4411
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-P-290007
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta4′-(4-Fluorophenoxy)acetophenone
CAS:Formula:C14H11FO2Purezza:97%Colore e forma:SolidPeso molecolare:230.238Phenacetin
CAS:Prodotto controllato<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Formula:C10H13NO2Colore e forma:WhitePeso molecolare:179.22rac-Ketoprofen Tris Base Amide
CAS:Prodotto controllato<p>Applications rac-Ketoprofen Tris Base Amide is derived from rac Ketoprofen (K200800), which is an anti-inflammatory and analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990);<br></p>Formula:C20H23NO5Colore e forma:NeatPeso molecolare:357.15762285rac Ketorolac Acyl-β-D-glucuronide (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Moisture Sensitive, Light Sensitive<br>Applications A metabolite of Ketorolac.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Brocks, D., et al.: Clin. Pharmacokinet., 23, 415 (1992), Vakily, M., et al.: Pharm. Res., 12, 1652 (1995), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Formula:C21H21NO9Colore e forma:NeatPeso molecolare:431.39Niflumic Acid
CAS:Prodotto controllato<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Formula:C13H9F3N2O2Colore e forma:Light YellowPeso molecolare:282.225-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Prodotto controllatoFormula:C13H14N2Colore e forma:NeatPeso molecolare:198.263'-Chloroacetophenone
CAS:Purezza:97.0%Colore e forma:Liquid, ClearPeso molecolare:154.58999633789062Ref: 10-F024871
1gPrezzo su richiesta25gPrezzo su richiesta100gPrezzo su richiesta500gPrezzo su richiesta4'-Methylacetophenone
CAS:Prodotto controllato<p>Impurity Celecoxib Impurity<br>Applications 4'-Methylacetophenone is a methylated acteophenone used in cosmetics and perfumery. The presence of 4'-Methylacetophenone has been shown to accelerate the photopolymerization of Methyl methacrylate.<br>References Dwivedi, U.N. et al.: Acta Polym., 39, 596 (1988); Opdyke, D.L.J. et al.: Food Cosm. Toxicol., 12, 933 (1974);<br></p>Formula:C9H10OColore e forma:NeatPeso molecolare:134.18Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Formula:C13H16N2Purezza:99.88%Colore e forma:SolidPeso molecolare:200.283-Hydroxy Medetomidine
CAS:Prodotto controllato<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Formula:C13H16N2OColore e forma:NeatPeso molecolare:216.283-Carboxy-α-methylbenzeneacetic Acid(Ketoprofen Impurity)
CAS:<p>Impurity Ketoprofen EP Impurity C; Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid)<br>Applications 3-Carboxy-α-methylbenzeneacetic Acid (Ketoprofen EP Impurity C) is a impurity of Ketoprofen (K200800). Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid)<br>References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Allegretti, M., et al.: J. Med. Chem., 48, 4312 (2005),<br></p>Formula:C10H10O4Colore e forma:Off-WhitePeso molecolare:194.183,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C10H12O5Colore e forma:White To BeigePeso molecolare:212.20Desmethyl Ketoprofen
CAS:Prodotto controllato<p>Impurity Ketoprofen EP Impurity B<br>Applications Desmethyl Ketoprofen (Ketoprofen EP Impurity B) shows antiinflammatory and analgesic activities. It can be used as neoplasm inhibitors and for treatment of angiogenesis-related disorders.<br>References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).<br></p>Formula:C15H12O3Colore e forma:WhitePeso molecolare:240.25rac N-Bisdesmethyl Tramadol, Hydrochloride
CAS:<p>Applications A metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C14H22ClNO2Colore e forma:NeatPeso molecolare:271.78Nitrobenzene
CAS:Prodotto controllato<p>Applications Nitrobenzene is a compound that exhibits chromosomal genotoxicity against hamster lung cells, and has the potential to cause cancer in humans (1,2). Nitrobenzene is also used as a starting material to synthesize 4-Aminophenol (A618920) through catalytic hydrogenation (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Bonacker, D. et al.: Arch. Toxicol. 2004 Jan;78(1):49-57.2. Hsu, C. et al.: J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 2007 Apr-Jun;25(2):155-843. Rode, C. et al.: Org. Proc. Res. Dev. 1999 Nov;3(6), pp 465–470<br></p>Formula:C6H5NO2Colore e forma:Light YellowPeso molecolare:123.114-Nitrophenol
CAS:Prodotto controllatoFormula:C6H5NO3Colore e forma:Light YellowPeso molecolare:139.113-(1-Cyanoethyl)benzoic Acid
CAS:Prodotto controllato<p>Applications 3-(1-Cyanoethyl)benzoic Acid is an intermediate for the synthetic preparation of various pharmaceutical compounds. 3-(1-Cyanoethyl)benzoic Acid was used in studies examining the enantioselectivity of nitrile hydratases.<br>References Rzeznicka, K., et al.: App. Microbiol. Biotechnol., 85, 1417 (2010); Van Pelt. S., et al.: Org. Biomole. Chem., 9, 3011 (2011);<br></p>Formula:C10H9NO2Colore e forma:BeigePeso molecolare:175.18rac 1-Methoxy Ketorolac
CAS:Prodotto controllato<p>Applications An impurity of the analgesic Ketorolac (K235650).<br></p>Formula:C16H15NO4Colore e forma:NeatPeso molecolare:285.294,5-Dimethyl-2-methoxyacetophenone
CAS:Formula:C11H14O2Purezza:95.0Colore e forma:SolidPeso molecolare:178.231(R)-Apomorphine-10-sulfate
CAS:Prodotto controllatoFormula:C17H17NO5SColore e forma:NeatPeso molecolare:347.39Ketoprofen Ethyl Ester
CAS:Prodotto controllato<p>Applications Ketoprofen ethyl ester is an impurity of Ketoprofen (K200800).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Borodkin, S., et al.: J. Pharm. Sci., 59, 481 (1970), Shanbag, V., et al.: J. Pharm. Sci., 81, 149 (1991), Khan, M., et al.: Eur. J. Med. Chem., 40, 371 (2005),<br></p>Formula:C18H18O3Colore e forma:ColourlessPeso molecolare:282.33(-)-Tramadol Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications An analgesic. Used in the treatment of urinary incontinence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)<br></p>Formula:C16H25NO2·ClHColore e forma:NeatPeso molecolare:299.844-Acetylamino-2-chlorophenol
CAS:Prodotto controllato<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C8H8ClNO2Colore e forma:White To Light PurplePeso molecolare:185.61Capsaicin-5,7-dene
Prodotto controllatoFormula:C18H25NO3Colore e forma:Off-WhitePeso molecolare:303.396Nordihydrocapsaicin
CAS:Prodotto controllato<p>Applications Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwai, K., et al.: Agri. Biol. Chem., 43, 2493 (1979); Kozukue, N., et al.: J. Agr. Food Chem., 53, 9172 (2005)<br></p>Formula:C17H27NO3Colore e forma:Off-WhitePeso molecolare:293.406-Methoxy-2-naphthaleneacetic Acid-d3 (Desmethyl Naproxen-d3)
CAS:Prodotto controllato<p>Applications A labelled metabolite of Nabumetone (N200500). A competitive, non-selective COX inhibitor.<br>References Turpeinen et. al.: Drug Metabolism and Dispositoin, 37: 1017 (2009); Daniels, F., et al.: J. Invest. Dermatol., 44, 259 (1965), Bosca, F., et al.: Photochem. Photobiol., 71, 173 (2000),<br></p>Formula:C13H9D3O3Colore e forma:White To Off-WhitePeso molecolare:219.25N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
CAS:Prodotto controllato<p>Impurity Acetaminophen Impurity B<br>Applications N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.<br>References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C16H16N2O4Colore e forma:NeatPeso molecolare:300.312′,4′,5′-Trifluoropropiophenone
CAS:Formula:C9H7F3OColore e forma:Low Melting SolidPeso molecolare:188.149Terpinolene (~90%)
CAS:Prodotto controllato<p>Applications Terpinolene is a chemical constituent of essential oils found in many plant species and exhibits analgesic and anti-inflammatory properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Macedo, E. M., et al.: Braz J Med Biol Res. 49, S0100 (2016); Garcia, G., et al.: Molecules. 22, E921 (2017)<br></p>Formula:C10H16Purezza:>85%Colore e forma:ColourlessPeso molecolare:136.234'-Isobutylacetophenone
CAS:Prodotto controllato<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Formula:C12H16OColore e forma:Colourless To Light YellowPeso molecolare:176.25
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