Chetoni e Derivati
I chetoni sono composti organici che contengono un gruppo carbonilico (C=O) legato a due atomi di carbonio, formando una struttura in cui il gruppo carbonilico è affiancato da gruppi alchilici o arilici. In farmacologia, i chetoni sono utilizzati nella formulazione di API grazie alla loro capacità di migliorare la solubilità e la stabilità dei principi attivi. Alcuni chetoni possiedono proprietà antinfiammatorie, analgesiche e antimicrobiche. I derivati dei chetoni includono composti in cui il gruppo carbonilico è modificato, come gli enoli, che trovano applicazione nella sintesi di farmaci e come intermedi chimici nella produzione di altri composti bioattivi. I derivati dei chetoni sono impiegati nella progettazione di nuovi farmaci, inclusi quelli per il trattamento di malattie neurodegenerative, disturbi metabolici e alcuni tipi di cancro, grazie ai loro effetti specifici sugli enzimi e sui processi cellulari.
Trovati 2393 prodotti di "Chetoni e Derivati"
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N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
CAS:Prodotto controllato<p>Impurity Acetaminophen Impurity B<br>Applications N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.<br>References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C16H16N2O4Colore e forma:NeatPeso molecolare:300.314-Acetaminophen Sulfate Potassium Salt
CAS:Prodotto controllatoFormula:C8H8NO5S·KColore e forma:BeigePeso molecolare:269.324-Acetylamino-2-chlorophenol
CAS:Prodotto controllato<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C8H8ClNO2Colore e forma:White To Light PurplePeso molecolare:185.611-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one
CAS:Purezza:97.0%Peso molecolare:426.4880065917969Ref: 10-F358088
1gPrezzo su richiesta5gPrezzo su richiesta25gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta(-)-N,N-Bisdesmethyl Tramadol
CAS:Prodotto controllato<p>Applications A optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C14H21NO2Colore e forma:NeatPeso molecolare:235.325-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Prodotto controllatoFormula:C13H14N2Colore e forma:NeatPeso molecolare:198.26Acetaminophen-d4 (major)
CAS:Prodotto controllato<p>Applications Acetaminophen-d4 (major) is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C82H4H5NO2Colore e forma:Off-WhitePeso molecolare:155.191-(4-(Phenylethynyl)phenyl)ethan-1-one
CAS:Purezza:95%Colore e forma:SolidPeso molecolare:220.27099611-Keto Ketorolac
CAS:Prodotto controllato<p>Impurity Ketorolac EP Impurity B; Ketorolac USP Related Compound C<br>Applications 1-Keto Ketorolac (Ketorolac EP Impurity B; Ketorolac USP Related Compound C) is a Ketorolac impurity. Ketorolac or ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, often used as an analgesic.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Formula:C14H11NO2Colore e forma:Light YellowPeso molecolare:225.24trans-Capsaicin-d3
CAS:Prodotto controllato<p>Applications Labelled Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Artursson., et al.: J. Pharma. Sci., 73, 1507 (1984), Fu., et al.: Pharma. Res., 17, 100 (2000),<br></p>Formula:C18H24D3NO3Colore e forma:NeatPeso molecolare:308.43rac-2’,4’,5’-Trimethyl Ketoprofen
CAS:Prodotto controllato<p>Applications rac-2,4’,5’-Trimethyl Ketoprofen is an impurity of Ketoprofen (K200800), an anti-inflammatory and analgesic agent.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Formula:C19H20O3Colore e forma:NeatPeso molecolare:296.36Ketoprofen Ethyl Ester
CAS:Prodotto controllato<p>Applications Ketoprofen ethyl ester is an impurity of Ketoprofen (K200800).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Borodkin, S., et al.: J. Pharm. Sci., 59, 481 (1970), Shanbag, V., et al.: J. Pharm. Sci., 81, 149 (1991), Khan, M., et al.: Eur. J. Med. Chem., 40, 371 (2005),<br></p>Formula:C18H18O3Colore e forma:ColourlessPeso molecolare:282.33Ref: 10-F506051
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta(R)-Apomorphine-10-sulfate
CAS:Prodotto controllatoFormula:C17H17NO5SColore e forma:NeatPeso molecolare:347.393-Ethylbenzophenone
CAS:Prodotto controllato<p>Applications 3-Ethylbenzophenone is the photodegradation product of Ibuprofen (I40000) and Ketoprofen (K200800)in aqueous solutions.<br>References Alapi, T., et al.: J. Photochem. Photobiol., 188, 409 (2007), Musa, K., et al.: Med. Chem., 50, 1735 (2007),<br></p>Formula:C15H14OColore e forma:NeatPeso molecolare:210.27Ref: 10-F386999
1gPrezzo su richiesta5gPrezzo su richiesta25gPrezzo su richiesta250mgPrezzo su richiestaAcetaminophen (1 mg/mL in Methanol)
CAS:Prodotto controllatoFormula:C8H9NO2Colore e forma:Single SolutionPeso molecolare:151.16Acetaminophen Mercapurate Disodium
CAS:<p>Applications Acetaminophen Mercapurate Disodium Salt is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)<br></p>Formula:C13H14N2O5S·2NaColore e forma:NeatPeso molecolare:356.31Flufenamic Acid-d4
CAS:Prodotto controllatoFormula:C14H6D4F3NO2Colore e forma:NeatPeso molecolare:285.25Acetaminophen-d3
CAS:Prodotto controllato<p>Applications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C82H3H6NO2Colore e forma:WhitePeso molecolare:154.18Medetomidine-13C,d3 Hydrochloride
CAS:Prodotto controllato<p>Applications Labelled α2-adrenergic agonist. Sedative; analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Formula:CC122H3H13N2·ClHColore e forma:White To Light YellowPeso molecolare:240.75Nabumetone
CAS:Prodotto controllato<p>Applications Nabumetone is an anti-inflammatory and antibacterial agent (1). A non-steroidal anti-inflammatory prodrug used for treatment of inflammatory and degenerative rheumatic diseases.<br>References (1) Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Formula:C15H16O2Colore e forma:NeatPeso molecolare:228.29Acetaminophen Dimer
CAS:<p>Applications Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986) (3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Formula:C16H16N2O4Colore e forma:NeatPeso molecolare:300.314,5-Dimethyl-2-methoxyacetophenone
CAS:Formula:C11H14O2Purezza:95.0Colore e forma:SolidPeso molecolare:178.231N-(1-Phenylethyl) Ibuprofen Amide(Mixture of 4 Diastereomers)
CAS:Prodotto controllato<p>Applications Ibuprofen (I140000) impurity, an anti-inflammatory compound.<br>References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),<br></p>Formula:C21H27NOColore e forma:WhitePeso molecolare:309.45Acetaminophen-cysteine
CAS:Prodotto controllatoFormula:C11H14N2O3SColore e forma:NeatPeso molecolare:254.31Paracetamol Impurity L
<p>Paracetamol Impurity L is a drug product that is used as an analytical standard for the impurity paracetamol. It is found in pharmaceuticals, such as acetaminophen, which is used to relieve pain and reduce fever. Paracetamol Impurity L is a natural compound and has been shown to be metabolically stable in humans. The CAS number for this compound is 619-25-4.</p>Formula:C16H16N2O4Purezza:Min. 95%Peso molecolare:300.31 g/molAcetaminophen acetate
CAS:<p>Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.</p>Formula:C10H11NO3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:193.2 g/mol5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:<p>5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.</p>Formula:C15H12BrO3NPurezza:Min. 95%Peso molecolare:334.16 g/molAll-trans-retinol-d5
CAS:Prodotto controllato<p>All-trans-retinol-d5 is a supplement that is used to protect the brain from oxidative damage and to help maintain healthy skin. It is an antioxidant that prevents free radicals from damaging cells and helps maintain the structural integrity of cell membranes. All-trans-retinol-d5 can be found in high concentrations in animal tissues, such as liver, lung, kidney, heart, brain, and eye. It can also be found in human urine. The presence of all-trans-retinol-d5 in urine has been correlated with neuroprotective effects. Retinol levels have been shown to be higher in children who are less obese than those who are obese or overweight. All-trans retinol has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting protein synthesis at the level of transcription.</p>Formula:C20H25D5OPurezza:(%) Min. 80%Colore e forma:Clear Viscous LiquidPeso molecolare:291.48 g/mol5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide, racemic
CAS:<p>5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide is a drug product that is used in research and development. It is a synthetic compound with niche applications. It has been shown to be metabolized in animal studies and the metabolism pathways have been elucidated. The analytical impurity standard for this drug product is 5-(benzoylamino)-N-[2-(hydroxymethyl)propanoyl]-2,3,-dihydro-1H-pyrrolizine-1 -carboxamide. This compound can be custom synthesized and also has an HPLC standard available.</p>Formula:C19H22N2O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:358.39 g/molMethyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS:<p>Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a particle that is used to treat cardiac arrhythmias. It has been shown to be effective as an antipyretic agent and may also have analgesic properties. Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a white powder that melts at temperatures of about 300°C. This drug can be administered by inhalation in the form of a vaporized liquid. The particle size of this drug is typically less than 10 microns in diameter. Methyl 5-benzoyl-2,3-dihydro-1H pyrrolizine 1 carboxylate can be administered through the respiratory tract as an aerosol or nebulizer. The molecular weight of this</p>Formula:C16H15NO3Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:269.3 g/molEthyl-(5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS:<p>Ethyl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic) is a molecule that can be used in the treatment of cardiac diseases. It is a cardiotonic agent that has been shown to shorten the duration of ventricular fibrillation and restore contractility. This drug also decreases the frequency and severity of angina pectoris and enhances coronary artery blood flow. The most effective dose for this drug is 1.5 mg per kg body weight. It is administered orally or intravenously and should not be used with fatty esters because it may cause hypotension. Ethyl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic) has been shown to have an effect on metal coordination profiles as well as an activated form of the molecule.</p>Formula:C17H17O3NPurezza:Min. 98 Area-%Colore e forma:Off-White PowderPeso molecolare:283.32 g/mol1-(4-Cyclopropylphenyl)ethanone
CAS:Formula:C11H12OPurezza:97%Colore e forma:LiquidPeso molecolare:160.2165′-Bromo-2′-hydroxy-4′-methylacetophenone
CAS:Formula:C9H9BrO2Purezza:98%Colore e forma:SolidPeso molecolare:229.0731-(4-Isopropoxyphenyl)ethanone
CAS:Formula:C11H14O2Purezza:98%Colore e forma:Liquid, No data available.Peso molecolare:178.2313′-Fluoro-5′-(trifluoromethyl)acetophenone
CAS:Formula:C9H6F4OPurezza:98%Colore e forma:LiquidPeso molecolare:206.141-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone
CAS:Formula:C9H7F3O2Purezza:97%Colore e forma:LiquidPeso molecolare:204.148
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