Derivati del Benzimidazolo e dell’Imidazolo
Il benzimidazolo è un composto costituito da un anello benzenico fuso con un anello imidazolico, una struttura a cinque membri contenente due atomi di azoto. I derivati del benzimidazolo, come l’albendazolo, sono noti per la loro attività antiparassitaria e antifungina, utilizzati nel trattamento delle infezioni parassitarie e di alcune malattie parassitarie negli animali e negli esseri umani. L’imidazolo, invece, è una struttura a cinque membri con due atomi di azoto, presente in vari composti biologicamente attivi. I derivati dell’imidazolo, come il metronidazolo, possiedono proprietà antimicrobiche e antiparassitarie. Questi composti sono impiegati anche nell’industria farmaceutica per il trattamento di infezioni batteriche, malattie parassitarie e alcune infezioni fungine, oltre ad avere applicazioni in chimica organica come catalizzatori.
Presso CymitQuimica, offriamo benzimidazoli e imidazoli ad alta purezza per la ricerca in chimica medicinale, farmacologia e biotecnologia.
Trovati 10354 prodotti di "Derivati del Benzimidazolo e dell’Imidazolo"
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2-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid
CAS:Purezza:95.0%Colore e forma:Solid, White - Pale yellow powderPeso molecolare:274.2900085449219Ref: 10-F235743
1kgPrezzo su richiesta25gPrezzo su richiesta100gPrezzo su richiesta500gPrezzo su richiestaO-Hydroxyethyl Metronidazole
CAS:Prodotto controllato<p>Applications O-Hydroxyethyl Metronidazole is the hydroxy ethyl analogue and impurity of the antiprotozoal agent Metronidazole (M338880). O-Hydroxyethyl Metronidazole as well as other 1-substituted-2-methyl-5-nitroimidazoles showed potential antitrichomonal activity.<br>References Kajfez, F. et al.: J. Med. Chem., 11, 167 (1968);<br></p>Formula:C8H13N3O4Colore e forma:Yellowish SolidPeso molecolare:215.21(S)-Pregabalin-13C3
CAS:Prodotto controllato<p>Applications (S)-Pregabalin-13C3, is the labeled analogue of (S)-Pregabalin (P704790), a S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C513C3H17NO2Colore e forma:Off-WhitePeso molecolare:162.2Ref: 10-F078782
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta250mgPrezzo su richiestarac 5,6-Dehydro Pregabalin
CAS:Prodotto controllato<p>Applications 5,6-Dehydropregabalin is an impurity of the anticonvulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Colore e forma:Off-WhitePeso molecolare:157.212-Chloro-5-(2H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
CAS:Purezza:97.0%Colore e forma:LiquidPeso molecolare:370.8299865722656Ref: 10-F467439
1gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiestaOmeprazole-d3 (benzimidazole-4,6,7-d3)
CAS:Prodotto controllato<p>Applications Omeprazole-d3 (benzimidazole-4,6,7-d3) (CAS# 934293-92-2) is a useful isotopically labeled research compound.<br></p>Formula:C17H16D3N3O3SColore e forma:Light BrownPeso molecolare:348.4410,11-Dihydro-10-hydroxy Carbamazepine-d3
CAS:Prodotto controllato<p>Applications A labelled metabolite of Oxcarbazepine (O869250).<br>References Burkhart, C., et al.: Clin. Exp. Allergy, 32, 1635 (2002), Pearce, R., et al.: Drug Metab. Dispos., 30, 1170 (2002), Naisbitt, D., et al.: Mol. Pharmacol., 63, 732 (2003), Farrell, J., et al.: Br. J. Clin. Pharmacol., 57, 690 (2004),<br></p>Formula:C152H3H11N2O2Colore e forma:Off WhitePeso molecolare:257.301’-Hydroxy Midazolam-d5
CAS:Prodotto controllato<p>Applications A labelled metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br>References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512(2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449(2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463(2007), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C182H5H8ClFN3OColore e forma:White To Off-WhitePeso molecolare:346.80Voriconazole N-Oxide
CAS:Prodotto controllato<p>Applications A metabolite of Voriconazole (V760000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997), Geist, M., et al.: Antimicrob. Agents. Chemother., 50, 3227 (2006), Yamazaki, H., et al.: Drug. Metab. Dispos., 34, 1803 (2006), Yamazaki, H., et al.: Xenobiotica, 36, 1201 (2006),<br></p>Formula:C16H14F3N5O2Colore e forma:WhitePeso molecolare:365.31Mebendazole
CAS:Prodotto controllato<p>Applications Mebendazole is an Anthelmintic (Nematodes).<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 16, 291 (1987)<br></p>Formula:C16H13N3O3Colore e forma:NeatPeso molecolare:295.29Ref: 10-F494546
1gPrezzo su richiesta2.5gPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta4-Nitro-2,3-lutidine N-Oxide
CAS:Prodotto controllato<p>Applications Nitropyridine oxide derivatives show carcinogenicity and mutagenicity.<br>References Nagao, M., et al.: Cancer Res., 32, 2369 (1972),<br></p>Formula:C7H8N2O3Colore e forma:NeatPeso molecolare:168.15(R)-Lansoprazole
CAS:<p>Stability Hygroscopic<br>Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColore e forma:Off White To Dark BrownPeso molecolare:369.362-Methoxy-4-nitroaniline
CAS:<p>Applications 2-Methoxy-4-nitroaniline is a derivative of 4-Nitroaniline (N491770), which is used in the synthesis of photorefractive polymers, as novel chromophores in analytical study. As well, due to the absorption spectrum associated with 4-Nitroaniline, it is used to determine catechol derivatives in syntheses.<br>References Nagaraja, P. et al.: J. Pharm. Biomed. Anal., 25, 417 (2001);<br></p>Formula:C7H8N2O3Colore e forma:YellowPeso molecolare:168.15Carbamazepine 10,11-Epoxide-d8 (Major)
CAS:Prodotto controllato<p>Applications A labelled metabolite of Carbamazepine (C175840).<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H4D8N2O2Colore e forma:White To Dark YellowPeso molecolare:260.32Itraconazole-d3
CAS:Prodotto controllatoFormula:C352H3H35Cl2N8O4Colore e forma:NeatPeso molecolare:708.65Benzoylmetronidazole
CAS:Prodotto controllato<p>Applications Benzoylmetronildazole is a new class of antiglycation agents used to treat diabetes mellitus. Benzoylmetronildazole is also a derivative of Metronidazole (M338880), an antibacterial in the treatment of rosacea.<br>References Zeb, A., et al.: Med. Chem., 8, 846 (2012); Kumari, N., et al.: Curr. Drug. Deliv., 9, 74 (2012); Elosta, A., et al.: Curr. DIabetes. Rev., 8, 92 (2012);<br></p>Formula:C13H13N3O4Colore e forma:WhitePeso molecolare:275.26N-Desmethyl,-N-nitroso-promethazine
CAS:Prodotto controllatoFormula:C16H17N3OSColore e forma:NeatPeso molecolare:299.39N-(2-aminoethyl)-2-(5-(3-phenoxyphenyl)-2H-tetrazol-2-yl)acetamide
CAS:Purezza:98%Peso molecolare:338.3710021972656N-(2-Chloro-5-methoxypyrimidin-4-yl)-1H-indazol-6-amine
CAS:Purezza:98%Peso molecolare:275.70001220703125Itraconazole
CAS:Prodotto controllato<p>Applications Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993);<br></p>Formula:C35H38Cl2N8O4Colore e forma:White To Off-WhitePeso molecolare:705.634-Methylenepiperidine Hydrochloride
CAS:Prodotto controllato<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>Formula:C6H11N•(HCl)Colore e forma:NeatPeso molecolare:97.1636461,2-Phenylenediamine
CAS:Prodotto controllato<p>Stability Light and Mositure Sensitive<br>Applications An amino substituted benzene used in the manufacture of dyes. Potential use in sensitive immunosensor for cancer biomarker.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Y. et al.: Anal. Bioanal. Chem., 400, 2141 (2011); Du, D. et al.: Anal. Chem., 82, 2989 (2010);<br></p>Formula:C6H8N2Colore e forma:White To Light YellowPeso molecolare:108.14Albendazole
CAS:<p>Applications Albendazole is an anthelmintic drug.<br>References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008); Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009);<br></p>Formula:C12H15N3O2SColore e forma:Off WhitePeso molecolare:265.335-Hydroxy Omeprazole-d3 Sodium Salt
CAS:Prodotto controllatoFormula:C17H15D3N3NaO4SColore e forma:White To Light YellowPeso molecolare:386.42N-methyl-1-(1-phenyl-1H-tetrazol-5-yl)cyclohexanamine
CAS:Purezza:95.0%Peso molecolare:257.34100341796875Lamotrigine
CAS:Prodotto controllato<p>Applications An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C9H7Cl2N5Colore e forma:NeatPeso molecolare:256.09(R)-5-Hydroxymethyl Tolterodine
CAS:Prodotto controllato<p>Applications A metabolite of Tolterodine (T535800), a muscarinic receptor antagonist used in the treatment of urinary incontinence.<br>References Palmer, L., et al.: J. Pharm. Biomed. Anal., 16, 155 (1997), Hills, C., et al.: Drugs, 55, 813 (1998), Wefer, J., et al.: World J. Urol., 19, 312 (2001),<br></p>Formula:C22H31NO2Colore e forma:NeatPeso molecolare:341.493-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinemethanol
CAS:Prodotto controllatoFormula:C9H10F3NO2Colore e forma:Light Beige To Light BrownPeso molecolare:221.07Midazolam Maleate
CAS:Prodotto controllatoFormula:C18H13ClFN3·C4H4O4Colore e forma:White To Off-WhitePeso molecolare:441.84N-Nitroso Methyl Aniline Derivative
CAS:Formula:C14H11ClN2O2Colore e forma:WhitePeso molecolare:274.70231-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic Acid
CAS:Prodotto controllato<p>Applications 1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic Acid is a metalobilite of Midazolam(M343000) which is a anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000),<br></p>Formula:C18H12ClFN2O3Colore e forma:NeatPeso molecolare:358.75Albendazole-d7
CAS:Prodotto controllato<p>Applications Labelled Albendazole (A511610). An anthelmintic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C12H8D7N3O2SColore e forma:NeatPeso molecolare:272.37Efinaconazole-N-oxide
CAS:Prodotto controllato<p>Applications Efinaconazole-N-oxide is a degradation product and potentially a metabolite of the anti-fungal drug Efinaconazole (E435070).<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4O2Colore e forma:NeatPeso molecolare:364.39rac Desethyl Oxybutynin Hydrochloride
CAS:Prodotto controllato<p>Applications A metabolite of the drug Oxybutynin. Used in the treatment of incontinence.<br>References Hughes, K., et al.: Xenobiotica, 22, 859 (1992), Oki, T., et al.: Biol. Pharm. Bull., 24, 491 (2001), Fetscher, C., et al.: Br. J. Pharmacol., 136, 64 (2002), Zobrist, R., et al.: Pharm. Res., 20, 103 (2003)<br></p>Formula:C20H27NO3·ClHColore e forma:BeigePeso molecolare:365.89Carbamazepine 10,11-Epoxide-d2 (Major)
CAS:Prodotto controllato<p>Applications A labelled metabolite of Carbamazepine (C175840).<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H10D2N2O2Colore e forma:NeatPeso molecolare:254.28Carbamazepine-d2 (Major)
CAS:Prodotto controllato<p>Applications Labelled Carbamazepine (C175840). Used in treatment of pain associated with trigeminal neuralgia. Anticonvulsant.<br>References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Formula:C15H10D2N2OColore e forma:NeatPeso molecolare:238.28rac-Pregabalin
CAS:Prodotto controllato<p>Applications A GABA analogue used as an anticonvulsant.Controlled substance in the United States.Not controlled in Germany<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H17NO2Colore e forma:White SolidPeso molecolare:159.233,4-Diaminoanisole
CAS:<p>Applications 3,4-Diaminoanisole (cas# 102-51-2) is a compound useful in organic synthesis.<br></p>Formula:C7H10N2OColore e forma:NeatPeso molecolare:138.172-(Chloromethyl)-1-phenyl-1H-benzo[d]imidazole
CAS:Purezza:95.0%Colore e forma:Liquid, No data available.Peso molecolare:242.7100067138672rac 5-Hydroxymethyl Tolterodine-d14
CAS:Prodotto controllatoFormula:C22H17D14NO2Purezza:90%Colore e forma:NeatPeso molecolare:355.57Atropic Acid
CAS:<p>Impurity Ipratropium EP Impurity D<br>Stability Light Sensitive<br>Applications Atropic acid (Ipratropium EP Impurity D) is an impurity of Ipratropium bromide (I740500) and Atropine Sulfate (A794625).<br>References Lyon, R., et al.: J. Pharm. Sci., 95, 1549 (2006), Loch, M., et al.: Toxicology, 233, 229 (2007), John, H., et al.: Anal. Bioanal. Chem., 396, 751 (2010),<br></p>Formula:C9H8O2Colore e forma:Off-WhitePeso molecolare:148.16Rufinamide-15N,d2
CAS:Prodotto controllato<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N315NOColore e forma:White SolidPeso molecolare:241.22-Chlorobenzophenone
CAS:<p>Impurity Clotrimazole EP Impurity E<br>Applications 2-Chlorobenzophenone (Clotrimazole EP Impurity E) is a metabolite of Clofedanol (C586920). Chlorobenzophenone is also used as a catalyst in the photocrosslinking of polyethylenes.<br>References Qu, B. et al.: J. Appl. Polym. Sci., 48, 701 (1993); Eckhardt, G. et al.: J. Clin. Chem. Clin. Biochem., 15, 687 (1977);<br></p>Formula:C13H9ClOColore e forma:NeatPeso molecolare:216.66rac Desethyl Oxybutynin-d5 Hydrochloride
CAS:Prodotto controllato<p>Applications A labelled metabolite of the drug Oxybutynin (D289475). Used in the treatment of incontinence.<br>References Hughes, K., et al.: Xenobiotica, 22, 859 (1992), Oki, T., et al.: Biol. Pharm. Bull., 24, 491 (2001), Fetscher, C., et al.: Br. J. Pharmacol., 136, 64 (2002), Zobrist, R., et al.: Pharm. Res., 20, 103 (2003)<br></p>Formula:C20H22D5NO3·HClColore e forma:White To Off-WhitePeso molecolare:334.47 + (36.46)Propantheline Bromide
CAS:Prodotto controllato<p>Applications Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.<br>References Levin, R. et al.: Neurol. Urodyn., 1, 221 (1982); Daniotti, S. et al.: Br. J. Pharmacol., 82, 305 (1984); Moller, J. et al .: Acta Med. Scand., 184, 201 (1968);<br></p>Formula:C23H30NO3·BrColore e forma:White To Off-WhitePeso molecolare:448.392-Mercaptobenzimidazole
CAS:Prodotto controllato<p>Impurity Rabeprazole EP Impurity F<br>Applications An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole (R070500)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beheshti, A., et al.: J. Food Sci., 75, C135 (2010), Rohrig, U., et al.: J. Med. Chem., 53, 1172 (2010),<br></p>Formula:C7H6N2SColore e forma:NeatPeso molecolare:150.20N-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl Lansoprazole
CAS:Prodotto controllato<p>Applications Lansoprazole (L175000) impurity.<br>References Wallmark, B., et al.: J. Gastroenterol., 20, 37 (1985), Barradell, L., et al.: Drugs, 44, 225 (1992), Reddy, K., et al.: Pharmazie, 65, 994 (2006),<br></p>Formula:C25H22F6N4O3SColore e forma:Beige To Light BrownPeso molecolare:572.52Cyanoacetamide
CAS:<p>Applications Cyanoacetamide has been used in photometric and fluorimetric postcolumn labeling.<br>References Honda S., et. al.: Anal. biochem., 134, 483(1983)<br></p>Formula:C3H4N2OColore e forma:NeatPeso molecolare:84.0767Modafinil Sulfone
CAS:Prodotto controllatoFormula:C15H15NO3SColore e forma:NeatPeso molecolare:289.3495Oxazepam
CAS:Prodotto controllato<p>Applications Anxiolytic; muscle relaxant (skeletal); anticonvulsant; ligand for the GABAA receptor benzodiazepine modulatory site. Controlled substance (depressant).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Sisenwine, et al.: Arzneim. Forsch., 22, 682 (1972), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 3, 441 (1974), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 6, 89 (1981),<br></p>Formula:C15H11ClN2O2Colore e forma:White To Off-WhitePeso molecolare:286.716-Hydroxy-2-mercaptobenzimidazole
CAS:Prodotto controllatoFormula:C7H6N2OSColore e forma:NeatPeso molecolare:166.201'-Hydroxy Triazolam
CAS:Prodotto controllato<p>Applications A metabolite of Triazolam (T767380(M)), which is a sedative; a controlled substance (depressant).<br>References Boxenbaum, H., et al.: J. Pharm. Pharm. Sci., 2, 47 (1999), Perloff, M., et al.: J. Pharmacol. Exp. Ther., 292, 618 (2000), Patki, K., et al.: Drug Metab. Dispos., 31, 938 (2003),<br></p>Formula:C17H12Cl2N4OColore e forma:Light GreenPeso molecolare:359.21Modafinil Carboxylate Methyl Ester
CAS:Prodotto controllato<p>Impurity Modafinil EP Impurity C<br>Applications Modafinil Carboxylate Methyl Ester (Modafinil EP Impurity C) is a Modafinil derivative.<br>References Lehr, H., et al.: J. Med. Chem., 6, 136 (1963), Saikawa, I., et al.: Chem. Pharm. Bull., 33, 5534 (1985),<br></p>Formula:C16H16O3SColore e forma:NeatPeso molecolare:288.361-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
CAS:<p>Impurity Miconazole EP Impurity F<br>Applications 1-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole (Miconazole EP Impurity F) is an impurity of Miconazole (M342505), an antifungal (1,2) agent (topical).<br>References 1. Godefroi, E. et al.: J. Med. Chem. 1969 Sep;12(5):784-91.2. Brugmans, J. et al.: Arch Dermatol. 1970 Oct;102(4):428-32.<br></p>Formula:C18H14Cl4N2OColore e forma:NeatPeso molecolare:416.135-Hydroxy Omeprazole Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications The main metabolite of Omeprazole.<br>References Renberg, L., et al.: Drug Metab. Dispos., 17, 69 (1989), Calabresi, L., et al.: Pharmacol. Res., 49, 493 (2004), Yin, O., et al.: J. Clin. Pharmacol., 44, 582 (2004),<br></p>Formula:C17H18N3NaO4SColore e forma:White To Light YellowPeso molecolare:383.40N-(tert-Butyl)-2-((4,5-diphenyloxazol-2-yl)thio)propanamide
CAS:Purezza:97.0%Peso molecolare:380.5100097656254-Isobutyl-2-pyrrolidinone (pregabalin lactam impurity)
CAS:<p>Impurity Pregabalin USP Related Compound C<br>Applications Pregabalin (P704800) intermediate. Pregabalin USP Related Compound C<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColore e forma:Light YellowPeso molecolare:141.212-Phenyloxazole-5-carboxylic acid
CAS:Formula:C10H7NO3Purezza:95%Colore e forma:SolidPeso molecolare:189.17(R)-Pregabalin
CAS:Prodotto controllato<p>Impurity Pregabalin USP Related Compound A<br>Applications R-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer). Pregabalin USP Related Compound A.<br>References Field, M.J. et al.: Br. J. Pharmacol., 132, 1 (2001); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993);<br></p>Formula:C8H17NO2Colore e forma:WhitePeso molecolare:159.23Methyl Methanesulfonate
CAS:<p>Applications Methyl Methanesulfonate is used as a reagent in the synthesis of 2-Methyllamotrigine (M315350); an impurity of Lamotrigine (L173250) which is an anticonvulsant that inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Also used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)<br></p>Formula:C2H6O3SColore e forma:Colourless LiquidPeso molecolare:110.134-Methyl Mebendazole
CAS:Prodotto controllato<p>Applications Mebendazole (M200500) related compound as anthelmintic agent.<br>References Raeymaekers, A.H.M., et al.: Arzneim.-Forsch., 28, 586 (1978),<br></p>Formula:C17H15N3O3Colore e forma:NeatPeso molecolare:309.32Modafinil-d5 (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications Labelled Modafinil (M482502). Modafinil is an α-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.This is a controlled substance (stimulant).<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999)<br></p>Formula:C152H5H10NO2SColore e forma:NeatPeso molecolare:278.38Iminostilbene
CAS:Prodotto controllato<p>Impurity Carbamazepine EP Impurity D<br>Applications A metabolite of Carbamazepine (CBZ) (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001),<br></p>Formula:C14H11NColore e forma:Yellow To Dark OrangePeso molecolare:193.24Omeprazole Sulfone N-Oxide
CAS:<p>Impurity Omeprazole EP Impurity I<br>Applications Omeprazole Sulfone N-Oxide (Omeprazole EP Impurity I) is a metabolite of Omeprazole. Impurity I.<br>References Stevens, C.M., et al.: J. Biol. Chem., 75, 182 (1950), Okamoto, S., et al.: Biochem. Biophys. Res. Commun., 101, 440 (1981)<br></p>Formula:C17H19N3O5SColore e forma:NeatPeso molecolare:377.418(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one (Mixture of Regioisomers)
CAS:Prodotto controllato<p>Impurity Omeprazole EP Impurity F+Omeprazole EP Impurity G<br>Stability Sample unstable under MS condition<br>Applications 8(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one(Mixture of Regioisomers) (Omeprazole EP Impurity F+Omeprazole EP Impurity G) is a mixture of regioisomers of Omeprazole Impurity.<br>References Rackur, G., et al.: Biochem. Biophys. Res. Commmun., 128, 477 (1985),<br></p>Formula:C16H13N3O2SColore e forma:NeatPeso molecolare:311.362-Methoxy-5-methyl-N,N-bis(1-methylethyl)-γ-phenyl-benzenepropanamine (2E)-2-Butenedioate
CAS:Prodotto controllato<p>Impurity Tolterodine USP Related Compound A<br>Applications 2-Methoxy-5-methyl-N,N-bis(1-methylethyl)-γ-phenyl-benzenepropanamine (2E)-2-Butenedioate (Tolterodine USP Related Compound A) is a related compound of Tolterodine (T535795), a muscarinic receptor antagonist.<br>References Nilvebrant, L., et al.: Life Sci., 60, 1129 (1997), Nilvebrant, L., et al.: Eur. J. Pharmacol., 327, 195 (1997), Brynne, N., et al.: Int. J. Clin. Pharmacol. Ther., 35, 287 (1997)<br></p>Formula:C23H33NO·(C4H4O4)Colore e forma:NeatPeso molecolare:339.51 + (116.07)cis-[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl-methyl)-1,3-dioxolan-4-yl]methyl Methanesulfonate
CAS:Prodotto controllato<p>Applications An intermediate in the synthesis of Itraconazole.<br></p>Formula:C14H15Cl2N3O5SColore e forma:NeatPeso molecolare:408.26Rivastigmine N-Oxide (Technical Grade)
CAS:Prodotto controllato<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Formula:C14H22N2O3Colore e forma:Light Yellow LiquidPeso molecolare:266.345-Desamino 5-Oxo-2,5-dihydro Lamotrigine
CAS:Prodotto controllato<p>Impurity Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C<br>Applications 5-Desamino 5-Oxo-2,5-dihydro Lamotrigine (Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C) is an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Formula:C9H6Cl2N4OColore e forma:White SolidPeso molecolare:257.082-Chlorotrityl Chloride (90%)
CAS:Prodotto controllato<p>Impurity Clotrimazole EP Impurity C<br>Applications 2-Chlorotrityl Chloride (Clotrimazole EP Impurity C) is used in convergent peptide synthesis. 2-Chlorotrityl Chloride is also used in the preparation of modified trityl nucleosides as inhibitors of P. falciparum dUTPase.<br>References Ruda, G.F. et al.: ChemMedChem, 6, 309 (2011); Athanassopoulos, P. et al.: Tetrahed. Lett., 36, 5645 (1995);<br></p>Formula:C19H14Cl2Purezza:90%Colore e forma:NeatPeso molecolare:313.22Rufinamide
CAS:<p>Applications Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColore e forma:White To Off-WhitePeso molecolare:238.194-Methoxy-2-nitroaniline(2-Nitro-p-anisidine)
CAS:Prodotto controllato<p>Applications Toxic to some wild and domestic birds and mice. Molluscicidal activity<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References De Abreu, F. et al.; Bioorg. Med. Chem. 9, 659 (2001); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 14, 111 (1985); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 12, 355 (1983)<br></p>Formula:C7H8N2O3Colore e forma:NeatPeso molecolare:168.152,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
CAS:Prodotto controllato<p>Applications An intermediate in the synthesis of Itraconazole.<br></p>Formula:C22H27N5O2Colore e forma:NeatPeso molecolare:393.48Iso Letrozole
CAS:<p>Impurity Letrozole EP Impurity A; Letrozole USP Related Compound A<br>Applications Isoletrozole (Letrozole EP Impurity A) is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.<br>References Fleming, F.F., et al.: J. Med. Chem., 53, 7902 (2010),<br></p>Formula:C17H11N5Colore e forma:NeatPeso molecolare:285.30Glycopyrrolate Bromide-d3 (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications Labelled analogue of Glycopyrrolate Bromide, a novel pharmaceutical compound based on PDE IV inhibitors. Glycopyrrolate Bromide is used in the treatment of respiratory complaints.<br>References Gomez, et al.: Br. J. Anaesth., 74, 549 (1995);<br></p>Formula:C19H25D3NO3·BrColore e forma:NeatPeso molecolare:401.354-Descarboxamido Rufinamide 4-Methyl Ester
CAS:Prodotto controllato<p>Applications 4-Descarboxamido Rufinamide 4-Methyl Ester is an impurity in the synthesis of Rufinamide (R701550), an antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C11H9F2N3O2Colore e forma:NeatPeso molecolare:253.20Metronidazole Acetate
CAS:Prodotto controllato<p>Applications Metronidazole Acetate is a protected Metronidazole (M338880). Metronidazole Acetate is an imidazole derivative with anti-trichomonas, antifungal and spermicidal activity.<br>References Kumar, L. et al.: ACS Med. Chem. Lett., 3, 83 (2012); Kumar, L. et al.: Eur. J. Med. Chem., 45, 817 (2010)<br></p>Formula:C8H11N3O4Colore e forma:NeatPeso molecolare:213.19Imidacloprid-3-hydroxy
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 2-Chloro-5-[[4,5-dihydro-2-(nitroamino)-1H-imidazol-1-yl]methyl]-3-pyridinol is an analog of Imidacloprid (I274990) which is an active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C9H10ClN5O3Colore e forma:White To Light BeigePeso molecolare:271.66(S)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:355.364990234375Atropine-d5
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Labelled Atropine. Mydriatic; antispasmodic; used in preanesthetic medication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),<br></p>Formula:C17H18D5NO3Colore e forma:Light Yellow SolidPeso molecolare:294.4(R)-Oxybutynin Chloride
CAS:Prodotto controllato<p>Applications The optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formula:C22H31NO3·ClHColore e forma:NeatPeso molecolare:393.95(S)-N-Methyl Pregabalin
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications The major metabolite of Pregabalin.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C9H19NO2Colore e forma:NeatPeso molecolare:173.252,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Prodotto controllato<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColore e forma:NeatPeso molecolare:285.26Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Prodotto controllato<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColore e forma:NeatPeso molecolare:444.575-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O4SColore e forma:NeatPeso molecolare:361.423-(2,3-Dichlorobenzamido) Lamotrigine
CAS:<p>Impurity Lamotrigine EP Impurity F/ Lamotrigine Related Compound D<br>Stability Light Sensitive<br>Applications 3-(2,3-Dichlorobenzamido) Lamotrigine (Lamotrigine EP Impurity F) an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Emami, J. et al.: J. Pharmac. Biomed. Anal., 40, 999 (2006); Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Formula:C16H9Cl4N5OColore e forma:NeatPeso molecolare:429.09Parbendazole
CAS:Prodotto controllato<p>Applications Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.<br>References Lahon, L.C.. et al.: Ind. J. Pharmacol., 26, 235 (1994); Havercroft, J.C., et al.: J. Cell. Sci., 49, 195 (1981);<br></p>Formula:C13H17N3O2Colore e forma:NeatPeso molecolare:247.29Ravuconazole-d4
CAS:Prodotto controllato<p>Applications Ergosterol biosynthesis inhibitor. Antifungal.<br>References Fung-Tomc., J.C., et al.: Antimicrob. Agents Chemother., 42, 313 (1988), Tsuruoka, A., et al.: Chem. Pharm. Bull., 46, 623 (1998), Gupta, A.K., et al.: J. Eur. Acad. Dermatol. Venereol., 19, 437 (2005),<br></p>Formula:C22H13D4F2N5OSColore e forma:NeatPeso molecolare:441.493-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Formula:C15H12N2O2Colore e forma:NeatPeso molecolare:252.27(R)-Rabeprazole Sodium Salt
CAS:Prodotto controllato<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Formula:C18H20N3NaO3SColore e forma:NeatPeso molecolare:381.42
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