Derivati del Benzimidazolo e dell’Imidazolo
Il benzimidazolo è un composto costituito da un anello benzenico fuso con un anello imidazolico, una struttura a cinque membri contenente due atomi di azoto. I derivati del benzimidazolo, come l’albendazolo, sono noti per la loro attività antiparassitaria e antifungina, utilizzati nel trattamento delle infezioni parassitarie e di alcune malattie parassitarie negli animali e negli esseri umani. L’imidazolo, invece, è una struttura a cinque membri con due atomi di azoto, presente in vari composti biologicamente attivi. I derivati dell’imidazolo, come il metronidazolo, possiedono proprietà antimicrobiche e antiparassitarie. Questi composti sono impiegati anche nell’industria farmaceutica per il trattamento di infezioni batteriche, malattie parassitarie e alcune infezioni fungine, oltre ad avere applicazioni in chimica organica come catalizzatori.
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Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate
CAS:<p>Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate is an analytical standard used to identify impurities in drug products. It is a metabolite of the drug product and has been shown to be safe for human consumption. The compound is a synthetic chemical that is not found naturally in the environment. CAS No. 180468-42-2</p>Formula:C18H19NO2Purezza:Min. 95%Peso molecolare:281.35 g/molOxybutynin EP Impurity E
CAS:<p>Oxybutynin EP Impurity E is a research and development impurity standard that is used in the synthesis of Oxybutynin. It can be synthesized by reacting 2-chloro-4-nitroaniline with potassium tert-butoxide, followed by acetylation with acetic anhydride. The purity and structure of this compound have been verified by gas chromatography, mass spectrometry, and melting point analysis. This impurity standard has a CAS number of 1215677-72-7.<br>Oxybutynin EP Impurity E is used as a drug product for the treatment of overactive bladder, urinary incontinence, and painful bladder syndrome/interstitial cystitis. It also helps to reduce pain due to spinal cord injury or multiple sclerosis. <br>The pharmacopoeia name for this compound is 4-(2-Chloroethyl)-1H-imidazoleacetic acid. It has been found to be</p>Formula:C23H33NO3Purezza:Min. 95%Peso molecolare:371.51 g/molOxybutynin EP impurity A
CAS:<p>Oxybutynin EP impurity A is a metabolite of oxybutynin, an antispasmodic drug. It has been shown to have immunomodulatory effects in a rat model of adjuvant arthritis. Oxybutynin EP impurity A is the major metabolite of oxybutynin and has been shown to be pharmacologically active in humans.</p>Purezza:Min. 95%1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole
CAS:<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.</p>Formula:C25H22F6N4O3SPurezza:Min. 95%Peso molecolare:572.52 g/molScopine-2,2-dithienyl glycolate
CAS:<p>Scopine-2,2-dithienyl glycolate is a catalyst that belongs to the class of dithienyl glycolates. Scopine-2,2-dithienyl glycolate is used in the pharmaceutical industry as an average catalyst for reactions and can be used to recover dimethylbenzene. The method of detection for scopine-2,2-dithienyl glycolate is based on its ability to absorb light at a wavelength of 360 nm. The reaction solution must be monitored carefully during the synthetic process because it has been shown that it can react with water or air and form hydrogen sulfide gas. If this happens, the reaction solution will become cloudy or turbid. This product is a white crystalline solid that appears as tiny needles and has a melting point of 173 degrees Celsius (340 degrees Fahrenheit).</p>Formula:C18H19NO4S2Purezza:Min. 95%Peso molecolare:377.48 g/mol(1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en bromide
CAS:<p>The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (</p>Formula:C19H22NO3S2·BrPurezza:Min. 95%Peso molecolare:456.42 g/molAbeprazan
CAS:<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>Formula:C19H17F3N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:410.41Zolazepam
CAS:<p>Zolazepam (CI 716), a pyrazole and diazazone derivative, is a benzodiazepine-like veterinary anesthetic.</p>Formula:C15H15FN4OColore e forma:SolidPeso molecolare:286.3(R,R)-Glycopyrrolate
CAS:<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Formula:C19H28BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:398.34Metopimazine
CAS:<p>Metopimazine is a selective and peripherally restricted dopamine D3 and D2 receptors antagonist.</p>Formula:C22H27N3O3S2Purezza:98%Colore e forma:SolidPeso molecolare:445.6(S)-4-(2-Methylpropyl)-2-pyrrolidinone
CAS:Prodotto controllato<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>Formula:C8H15NOPurezza:Min. 95%Colore e forma:PowderPeso molecolare:141.21 g/molProchloraz
CAS:<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Formula:C15H16Cl3N3O2Purezza:99.75% - 99.79%Colore e forma:Colorless SolidPeso molecolare:376.67Omeprazole Sodium
CAS:<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Formula:C17H18N3NaO3SPurezza:99.84%Colore e forma:Clear In WaterPeso molecolare:367.4Morinidazole
CAS:<p>Morinidazole has antibacterial properties for researching anaerobic infections like appendicitis and PID.</p>Formula:C11H18N4O4Purezza:98.92% - 99.82%Colore e forma:SolidPeso molecolare:270.29Pantoprazole sulphide
CAS:<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formula:C16H15F2N3O3SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:367.37 g/molOrphenadrine
CAS:<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Formula:C18H23NOPurezza:98.91% - 99.11%Colore e forma:SolidPeso molecolare:269.385,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
CAS:<p>5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.</p>Formula:C17H15NO3Purezza:Min. 95%Peso molecolare:281.31 g/molPregabalin CV
CAS:Prodotto controllatoAmino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormula:C8H17NO2Colore e forma:Off-White PowderPeso molecolare:159.12593Isopropyl 2-hydroxy-2-phenylacetate
CAS:<p>Isopropyl 2-hydroxy-2-phenylacetate is an inorganic acid that is used as a solvent and as a reagent for sample preparation. It has been shown to be able to dissolve hydroxy methyl cellulose, which is a common component of membranes. In addition, it can be used as an electrospray ionization source and has been shown to have a phase transition temperature of -24 degrees Celsius. Isopropyl 2-hydroxy-2-phenylacetate has also been shown to inhibit the action of cholic acid on kinetics in high-performance liquid chromatography. This chemical compound also contains an ethyl group, which may be due to its derivation from acetone.</p>Formula:C11H14O3Purezza:Min. 95%Peso molecolare:194.23 g/mol(1-Nitroethyl)benzene
CAS:<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>Formula:C8H9NO2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:151.16 g/mol(S)-Rabeprazole sodium
CAS:<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formula:C18H21N3O3S•NaPurezza:Min. 95%Peso molecolare:382.43 g/molTroriluzole
CAS:<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Formula:C15H16F3N5O4SPurezza:97.14%Colore e forma:SolidPeso molecolare:419.38L-163491
CAS:<p>L-163491: partial agonist at angiotensin II receptor type 1, less so at type 2, used in research, may treat viral lung inflammation.</p>Formula:C36H40N4O5SColore e forma:SolidPeso molecolare:640.79Aclidinium
CAS:<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Formula:C26H30NO4S2Colore e forma:SolidPeso molecolare:484.65Donepezil Quaternary Salt (Donepezilbenzyl Bromide) (1,1-dibenzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidin-1-ium, bromide; 1,1-dibenzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidinium, bromide)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C31H36BrNO3Colore e forma:White Off-White SolidPeso molecolare:549.18786Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C16H17N3O2SColore e forma:White Off-White SolidPeso molecolare:315.10415rac-4,5-Dehydropregabalin (3-(aminomethyl)-5-methylhex-4-enoic acid)
CAS:Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormula:C8H15NO2Colore e forma:Off-White SolidPeso molecolare:157.11028Isavuconazole Impurity 20 Chloride HCl (Mixture of Diastereomers)
CAS:Formula:C32H30F2N7O4S·Cl·HClColore e forma:Off-White SolidPeso molecolare:646.69 35.45 36.46Dextromethorphan EP Impurity D
CAS:Formula:C18H25NOColore e forma:Colorless OilPeso molecolare:271.40Pregabalin Impurity PD0310887
CAS:Formula:C14H25NO6Colore e forma:White To Off-White SolidPeso molecolare:303.36Fesoterodine Impurity 20
CAS:Formula:C22H29NOColore e forma:White To Off-White SolidPeso molecolare:323.48Carbamazepine EP Impurity D (Carbamazepine USP Related Compound B, Iminostilbene)
CAS:Formula:C14H11NColore e forma:Yellow SolidPeso molecolare:193.25Solifenacin Related Compound 17 (Dimethyl Carbonate)
CAS:Formula:C3H6O3Colore e forma:Colorless LiquidPeso molecolare:90.08Pregabalin Lactose Conjugate Impurity
Formula:C20H35NO11Colore e forma:Off-White SolidPeso molecolare:465.50Vonoprazan Impurity 7
CAS:Formula:C17H20FN3O2SColore e forma:White To Off-White SolidPeso molecolare:349.43tert-Butyl 5-((2-(3-Hydroxyphenyl)quinazolin-4-yl)amino)-1H-Indazole-1-Carboxylate
Formula:C26H23N5O3Peso molecolare:453.502-Piperazin-1-yl-1H-benzoimidazole
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:202.26100158691406Ethyl 5-Methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS:Colore e forma:SolidPeso molecolare:170.16799926757812(1,2,4-Triazol-4-yl) Itraconazole
CAS:Prodotto controllato<p>Impurity Itraconazole EP Impurity B<br>Applications (1,2,4-Triazol-4-yl) Itraconazole (Itraconazole EP Impurity B) is an isomer of Itraconazole. It is a COVID19-related research product.<br></p>Formula:C35H38Cl2N8O4Colore e forma:Off White SolidPeso molecolare:705.63(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine Dimaleate
CAS:Prodotto controllatoFormula:C16H16ClN3•2(C4H4O4)Colore e forma:NeatPeso molecolare:401.11423
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