Informazioni sul prodotto
- Orphenadrine (free base)
- (.+-.)-Orphenadrine
- 2-Methyldiphenhydramine
- Biorphen
- Brocadisipal
- Bs 5930
- Ethylamine, N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]-
- N,N-Dimethyl-2-(o-methyl-α-phenylbenzyloxy)ethylamine
- N,N-Dimethyl-2-[(2-methylphenyl)phenylmethoxy]ethanamine
- N,N-Dimethyl-N-[2-(o-methyl-α-phenylbenzyloxy)ethyl]amine
- Vedi altri sinonimi
- ORP
- Orfenadrina
- Orphenadine
- Orphenadrin
- Phenyl-o-tolylmethyl dimethylaminoethyl ether
- Ws 2434
- o-Methyldiphenhydramine
Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner, producing an IC of 0.85 μM in HEK cells.Orphenadrine is an antagonist of central and peripheral muscarinic receptors. Attenuation is blocked by mutations in pore residues Y652 or F656. Orphenadrine has antispasmodic, analgesic, and anticholinergic activity and protects against glutamatergic neurotoxicity in vitro and in vivo.Orphenadrine has inhibitory effects on sodium channels and can be used in the treatment of Parkinson's disease.
Proprietà chimiche
Richiesta tecnica su: TM-T68599 Orphenadrine
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