Derivati del Benzimidazolo e dell’Imidazolo
Il benzimidazolo è un composto costituito da un anello benzenico fuso con un anello imidazolico, una struttura a cinque membri contenente due atomi di azoto. I derivati del benzimidazolo, come l’albendazolo, sono noti per la loro attività antiparassitaria e antifungina, utilizzati nel trattamento delle infezioni parassitarie e di alcune malattie parassitarie negli animali e negli esseri umani. L’imidazolo, invece, è una struttura a cinque membri con due atomi di azoto, presente in vari composti biologicamente attivi. I derivati dell’imidazolo, come il metronidazolo, possiedono proprietà antimicrobiche e antiparassitarie. Questi composti sono impiegati anche nell’industria farmaceutica per il trattamento di infezioni batteriche, malattie parassitarie e alcune infezioni fungine, oltre ad avere applicazioni in chimica organica come catalizzatori.
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Trovati 10376 prodotti di "Derivati del Benzimidazolo e dell’Imidazolo"
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Oxybutynin EP Impurity E
CAS:<p>Oxybutynin EP Impurity E is a research and development impurity standard that is used in the synthesis of Oxybutynin. It can be synthesized by reacting 2-chloro-4-nitroaniline with potassium tert-butoxide, followed by acetylation with acetic anhydride. The purity and structure of this compound have been verified by gas chromatography, mass spectrometry, and melting point analysis. This impurity standard has a CAS number of 1215677-72-7.<br>Oxybutynin EP Impurity E is used as a drug product for the treatment of overactive bladder, urinary incontinence, and painful bladder syndrome/interstitial cystitis. It also helps to reduce pain due to spinal cord injury or multiple sclerosis. <br>The pharmacopoeia name for this compound is 4-(2-Chloroethyl)-1H-imidazoleacetic acid. It has been found to be</p>Formula:C23H33NO3Purezza:Min. 95%Peso molecolare:371.51 g/molN,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride
CAS:Prodotto controllato<p>N,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride (DMAEA) is a drug that is used as an ophthalmic. It has been shown to be safe and effective in patients with chronic open angle glaucoma, and it may also have some efficacy for the treatment of other conditions such as uveitis and retinal detachment. DMAEA is thought to work by binding to the DNA in the eye’s optic nerve cells and blocking the production of leukotrienes. This drug has also been shown to have anti-inflammatory properties.</p>Formula:C17H26ClNO3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:327.85 g/mol7-Hydroxyhyoscyamine
CAS:<p>7-Hydroxyhyoscyamine is an antibacterial agent that is used in the treatment of bacterial infections. It has been shown to inhibit the growth of a number of bacteria including Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli. 7-Hydroxyhyoscyamine has been shown to be more potent than 6-hydroxyhyoscyamine (6-OH Hya) for inhibiting protein synthesis in the bacteria. The compound does not have any psychoactive effects, unlike atropine sulfate, which is also an alkaloid found in plants from the Solanaceae family. 7-Hydroxyhyoscyamine can be synthesized by reacting atropine with nitrous acid or hydrochloric acid. This synthetic process leads to n-oxides as impurities, which can be removed by using a reversed phase high performance liquid chromatography (RP HPLC). Validation of this</p>Formula:C17H23NO4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:305.4 g/molSolifenacin Impurity D
CAS:<p>Solifenacin Impurity D is a synthetic impurity of solifenacin. Solifenacin is an anti-cholinergic drug used to treat overactive bladder and urinary incontinence. The purity of this product is 99%. It is soluble in methanol, ethanol, chloroform, and acetone. Solifenacin Impurity D can be used as a reference material for analytical purposes or as an impurity standard in the development of new drugs.</p>Formula:C31H28N2OPurezza:Min. 96 Area-%Colore e forma:White PowderPeso molecolare:444.57 g/molCarbamazepine impurity
CAS:<p>Carbamazepine is a drug that has been used to treat epileptic seizures and trigeminal neuralgia. Impurities in the drug are removed by using chromatographic methods, such as high-performance liquid chromatography (HPLC). The rotarod test is an animal model of motor coordination and balance that can be used to assess the effects of drugs on these functions. Carbamazepine impurities may cause depression and have an epileptic effect on animals. Chronic exposure to carbamazepine can lead to drug reactions and gene polymorphisms, which may alter the metabolism of the drug. Analytical methods for determining carbamazepine impurities include HPLC, gas chromatography mass spectrometry (GC-MS), and thin-layer chromatography (TLC).</p>Formula:C15H14N2OPurezza:Min. 95%Peso molecolare:238.28 g/molDonepezil benzyl bromide (donepezil impurity)
CAS:<p>Donepezil benzyl bromide is a by-product of donepezil hydrochloride, which is an industrially important drug used to treat Alzheimer's disease. It has been shown to be more efficient than its hydrochloride form. Donepezil benzyl bromide is a crystalline substance that is insoluble in water and soluble in organic solvents such as acetone or ethanol. The compound can be purified through recrystallization from an appropriate solvent.</p>Formula:C31H36BrNO3Purezza:Min. 95%Peso molecolare:550.53 g/molOmeprazole Sodium
CAS:<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Formula:C17H18N3NaO3SPurezza:99.84%Colore e forma:Clear In WaterPeso molecolare:367.4Prochloraz
CAS:<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Formula:C15H16Cl3N3O2Purezza:99.75% - 99.79%Colore e forma:Colorless SolidPeso molecolare:376.67Metopimazine
CAS:<p>Metopimazine is a selective and peripherally restricted dopamine D3 and D2 receptors antagonist.</p>Formula:C22H27N3O3S2Purezza:98%Colore e forma:SolidPeso molecolare:445.6Abeprazan
CAS:<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>Formula:C19H17F3N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:410.41(S)-4-(2-Methylpropyl)-2-pyrrolidinone
CAS:Prodotto controllato<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>Formula:C8H15NOPurezza:Min. 95%Colore e forma:PowderPeso molecolare:141.21 g/molZolazepam
CAS:<p>Zolazepam (CI 716), a pyrazole and diazazone derivative, is a benzodiazepine-like veterinary anesthetic.</p>Formula:C15H15FN4OColore e forma:SolidPeso molecolare:286.3(R,R)-Glycopyrrolate
CAS:<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Formula:C19H28BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:398.34Isopropyl 2-hydroxy-2-phenylacetate
CAS:<p>Isopropyl 2-hydroxy-2-phenylacetate is an inorganic acid that is used as a solvent and as a reagent for sample preparation. It has been shown to be able to dissolve hydroxy methyl cellulose, which is a common component of membranes. In addition, it can be used as an electrospray ionization source and has been shown to have a phase transition temperature of -24 degrees Celsius. Isopropyl 2-hydroxy-2-phenylacetate has also been shown to inhibit the action of cholic acid on kinetics in high-performance liquid chromatography. This chemical compound also contains an ethyl group, which may be due to its derivation from acetone.</p>Formula:C11H14O3Purezza:Min. 95%Peso molecolare:194.23 g/mol(1-Nitroethyl)benzene
CAS:<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>Formula:C8H9NO2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:151.16 g/molOrphenadrine
CAS:<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Formula:C18H23NOPurezza:98.91% - 99.11%Colore e forma:SolidPeso molecolare:269.38(S)-Rabeprazole sodium
CAS:<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formula:C18H21N3O3S•NaPurezza:Min. 95%Peso molecolare:382.43 g/molPregabalin CV
CAS:Prodotto controllatoAmino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormula:C8H17NO2Colore e forma:Off-White PowderPeso molecolare:159.12593Troriluzole
CAS:<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Formula:C15H16F3N5O4SPurezza:97.14%Colore e forma:SolidPeso molecolare:419.38Pantoprazole sulphide
CAS:<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formula:C16H15F2N3O3SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:367.37 g/mol5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
CAS:<p>5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.</p>Formula:C17H15NO3Purezza:Min. 95%Peso molecolare:281.31 g/molMorinidazole
CAS:<p>Morinidazole has antibacterial properties for researching anaerobic infections like appendicitis and PID.</p>Formula:C11H18N4O4Purezza:98.92% - 99.82%Colore e forma:SolidPeso molecolare:270.29L-163491
CAS:<p>L-163491: partial agonist at angiotensin II receptor type 1, less so at type 2, used in research, may treat viral lung inflammation.</p>Formula:C36H40N4O5SColore e forma:SolidPeso molecolare:640.79Aclidinium
CAS:<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Formula:C26H30NO4S2Colore e forma:SolidPeso molecolare:484.65Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C16H17N3O2SColore e forma:White Off-White SolidPeso molecolare:315.10415Donepezil Quaternary Salt (Donepezilbenzyl Bromide) (1,1-dibenzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)piperidin-1-ium, bromide; 1,1-dibenzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidinium, bromide)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C31H36BrNO3Colore e forma:White Off-White SolidPeso molecolare:549.18786rac-4,5-Dehydropregabalin (3-(aminomethyl)-5-methylhex-4-enoic acid)
CAS:Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoiFormula:C8H15NO2Colore e forma:Off-White SolidPeso molecolare:157.11028Vonoprazan Impurity 7
CAS:Formula:C17H20FN3O2SColore e forma:White To Off-White SolidPeso molecolare:349.43Solifenacin Related Compound 17 (Dimethyl Carbonate)
CAS:Formula:C3H6O3Colore e forma:Colorless LiquidPeso molecolare:90.08Carbamazepine EP Impurity D (Carbamazepine USP Related Compound B, Iminostilbene)
CAS:Formula:C14H11NColore e forma:Yellow SolidPeso molecolare:193.25Isavuconazole Impurity 20 Chloride HCl (Mixture of Diastereomers)
CAS:Formula:C32H30F2N7O4S·Cl·HClColore e forma:Off-White SolidPeso molecolare:646.69 35.45 36.46Pregabalin Impurity PD0310887
CAS:Formula:C14H25NO6Colore e forma:White To Off-White SolidPeso molecolare:303.36Dextromethorphan EP Impurity D
CAS:Formula:C18H25NOColore e forma:Colorless OilPeso molecolare:271.40Fesoterodine Impurity 20
CAS:Formula:C22H29NOColore e forma:White To Off-White SolidPeso molecolare:323.48Pregabalin Lactose Conjugate Impurity
Formula:C20H35NO11Colore e forma:Off-White SolidPeso molecolare:465.50tert-Butyl 5-((2-(3-Hydroxyphenyl)quinazolin-4-yl)amino)-1H-Indazole-1-Carboxylate
Formula:C26H23N5O3Peso molecolare:453.50Ethyl 5-Methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS:Colore e forma:SolidPeso molecolare:170.167999267578122-Piperazin-1-yl-1H-benzoimidazole
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:202.26100158691406(1,2,4-Triazol-4-yl) Itraconazole
CAS:Prodotto controllato<p>Impurity Itraconazole EP Impurity B<br>Applications (1,2,4-Triazol-4-yl) Itraconazole (Itraconazole EP Impurity B) is an isomer of Itraconazole. It is a COVID19-related research product.<br></p>Formula:C35H38Cl2N8O4Colore e forma:Off White SolidPeso molecolare:705.63(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine Dimaleate
CAS:Prodotto controllatoFormula:C16H16ClN3•2(C4H4O4)Colore e forma:NeatPeso molecolare:401.11423
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