Derivati del Benzimidazolo e dell’Imidazolo
Il benzimidazolo è un composto costituito da un anello benzenico fuso con un anello imidazolico, una struttura a cinque membri contenente due atomi di azoto. I derivati del benzimidazolo, come l’albendazolo, sono noti per la loro attività antiparassitaria e antifungina, utilizzati nel trattamento delle infezioni parassitarie e di alcune malattie parassitarie negli animali e negli esseri umani. L’imidazolo, invece, è una struttura a cinque membri con due atomi di azoto, presente in vari composti biologicamente attivi. I derivati dell’imidazolo, come il metronidazolo, possiedono proprietà antimicrobiche e antiparassitarie. Questi composti sono impiegati anche nell’industria farmaceutica per il trattamento di infezioni batteriche, malattie parassitarie e alcune infezioni fungine, oltre ad avere applicazioni in chimica organica come catalizzatori.
Presso CymitQuimica, offriamo benzimidazoli e imidazoli ad alta purezza per la ricerca in chimica medicinale, farmacologia e biotecnologia.
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8-Chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-3H-Imidazo[1,5-a][1,4]benzodiazepine (>90%)
CAS:Prodotto controllatoFormula:C18H15ClFN3Purezza:>90%Colore e forma:Off-White To YellowPeso molecolare:327.782-((4,5-Diphenyloxazol-2-yl)thio)-N-(1-hydroxypropan-2-yl)acetamide
CAS:Purezza:97%Peso molecolare:368.450012207031255-Phenylthio-2-aminobenzimidazole
CAS:Prodotto controllato<p>Applications 5-Phenylthio-2-aminobenzimidazole, is a derivative of Fenbendazole (F246750), an anthelmintic.<br>References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),<br></p>Formula:C13H11N3SColore e forma:Light Brown To OrangePeso molecolare:241.314-Isobutyl-2-pyrrolidinone (pregabalin lactam impurity)
CAS:<p>Impurity Pregabalin USP Related Compound C<br>Applications Pregabalin (P704800) intermediate. Pregabalin USP Related Compound C<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColore e forma:Light YellowPeso molecolare:141.21Benznidazole
CAS:<p>Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.<br>References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),<br></p>Formula:C12H12N4O3Colore e forma:NeatPeso molecolare:260.253-Amino-1H-indazole-5-carboxylic acid
CAS:Formula:C8H7N3O2Purezza:95.0%Colore e forma:SolidPeso molecolare:177.163Efinaconazole
CAS:Prodotto controllato<p>Applications Efinaconazole is a topical antifungal for onychomycosis. (Synonyms: KP-103)<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4OColore e forma:NeatPeso molecolare:348.39(2-Chlorophenyl)diphenylmethanol
CAS:<p>Impurity Clotrimazole EP Impurity A<br>Applications (2-Chlorophenyl)diphenylmethane (Clotrimazole EP Impurity A) is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is a degradation product of the antifungal agent Clotrimazole (C587400). Clotrimazole Related Compound A<br>References Suzuki, M. Iyak. Kenk., 23, 44 (1992); Hajkova, R. et al.: Talanta, 73, 483 (2007); Sabourin, L. et al.: Environ. Toxicol. Chem., 30, 582 (2011);<br></p>Formula:C19H15ClOColore e forma:NeatPeso molecolare:294.77N-Pentanoyl-N-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-L-valine
CAS:Purezza:97%Peso molecolare:677.8489990234375Secnidazole
CAS:Prodotto controllato<p>Applications Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H11N3O3Colore e forma:White To Light YellowPeso molecolare:185.182-(Chloromethyl)-1-phenyl-1H-benzo[d]imidazole
CAS:Purezza:95.0%Colore e forma:Liquid, No data available.Peso molecolare:242.7100067138672N-[3-(1H-imidazol-1-yl)propyl]-4-methyl-1,3-benzothiazol-2-amine
CAS:Purezza:95.0%Peso molecolare:272.3699951171875rac Rivastigmine-d6
CAS:Prodotto controllato<p>Applications Labelled rac Rivastigmine. A brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C14H16D6N2O2Colore e forma:NeatPeso molecolare:256.37Iminodibenzyl 5-Carbonyl Chloride
CAS:Prodotto controllatoFormula:C15H12ClNOColore e forma:NeatPeso molecolare:257.712-METHOXY-5-(5-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PHENOL
CAS:Purezza:95.0%Peso molecolare:317.3479919433594TRAM-34
CAS:Prodotto controllato<p>Applications TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity.<br>References Wulff, H., et al.: J. of Biological Chemistry, 276, 34, 32040 (2001)<br></p>Formula:C22H17ClN2Colore e forma:NeatPeso molecolare:344.84Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Prodotto controllato<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColore e forma:NeatPeso molecolare:444.57Temazepam b-D-Glucuronide, Mixture of Diastereomers
CAS:Prodotto controllato<p>Applications A glucuronide metabolite of Diazepam.Controlled substance (depressant). Sedative, hypnotic.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C22H21ClN2O8Colore e forma:Off-WhitePeso molecolare:476.86Iminostilbene
CAS:Prodotto controllato<p>Impurity Carbamazepine EP Impurity D<br>Applications A metabolite of Carbamazepine (CBZ) (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001),<br></p>Formula:C14H11NColore e forma:Yellow To Dark OrangePeso molecolare:193.24Lamotrigine N2-Oxide
CAS:Prodotto controllato<p>Applications Lamotrigine analog for production of anti-lamotrigine antibodies and use as immunoassay reagent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Doig, M.V., et al.: J. Chromatogr., 554, 181 (1991),<br></p>Formula:C9H7Cl2N5OPurezza:90%Colore e forma:NeatPeso molecolare:272.09Imidacloprid-d4
CAS:Prodotto controllato<p>Applications Imidacloprid-d4 is labelled Imidacloprid (I274990) which is a neonicotinoid, the active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C92H4H6ClN5O2Colore e forma:WhitePeso molecolare:259.69Imidacloprid
CAS:Prodotto controllato<p>Applications A neonicotinoid; the active ingredient in certain neuro-active insecticides. Reports show that when exposed to neonicotinid pesticides honeybees have problems returning home after foraging and bumblebee colonies grow poorly and produce fewer queens. Imidacloprid is useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C9H10ClN5O2Colore e forma:NeatPeso molecolare:255.662-[(Tetrahydro-1,1-dioxido-3-thienyl)methyl]-1H-benzimidazole
CAS:Purezza:97%Peso molecolare:250.320007324218755-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methylbenzoic acid
CAS:Purezza:97%Peso molecolare:260.26800537109375Omeprazole Sulfide
CAS:Prodotto controllatoFormula:C17H19N3O2SColore e forma:White To Light BrownPeso molecolare:329.421H-Benzo[d]imidazole-5-carbohydrazide
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:176.1790008544922cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol
CAS:Prodotto controllatoFormula:C13H13Cl2N3O3Colore e forma:NeatPeso molecolare:330.17Benzhydrol-d5
CAS:Prodotto controllato<p>Applications Intermediate in the preparation of labelled Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Formula:C13D5H7OColore e forma:NeatPeso molecolare:189.264-Nitro-1H-imidazole
CAS:Prodotto controllato<p>Applications Metronidazole (M338880) derivative, an antibacterial in the treatment of rosacea and inflammatory bowel disease.<br>References Khan, K. et al.; Am. J. Gastroenterol. 106, 661 (2011)<br></p>Formula:C3H3N3O2Colore e forma:NeatPeso molecolare:113.071-Cyclopropyl-1H-benzo[d]imidazol-2(3H)-one
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:174.20300292968752-(1H-tetrazol-5-yl)ethanol
CAS:Formula:C3H6N4OPurezza:95.0%Colore e forma:SolidPeso molecolare:114.108Omeprazole Sulfone N-Oxide
CAS:<p>Impurity Omeprazole EP Impurity I<br>Applications Omeprazole Sulfone N-Oxide (Omeprazole EP Impurity I) is a metabolite of Omeprazole. Impurity I.<br>References Stevens, C.M., et al.: J. Biol. Chem., 75, 182 (1950), Okamoto, S., et al.: Biochem. Biophys. Res. Commun., 101, 440 (1981)<br></p>Formula:C17H19N3O5SColore e forma:NeatPeso molecolare:377.41N-(3-(1H-imidazol-1-yl)propyl)-4-ethoxybenzo[d]thiazol-2-amine
CAS:Purezza:95.0%Peso molecolare:302.3999938964844para-Clotrimazole Isomer
CAS:Prodotto controllato<p>Impurity Clotrimazole EP Impurity B<br>Applications para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.<br>References Buechel, K.H. et al.: Drugs Made Ger., 15, 79 (1972); Bachmann, K. et al.: Pharmacol. Res., 50, 237 (2004);<br></p>Formula:C22H17ClN2Colore e forma:NeatPeso molecolare:344.84Benzyl (3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)carbamate
CAS:Purezza:97%Peso molecolare:404.40499877929694-Hydroxy Midazolam
CAS:Prodotto controllato<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColore e forma:Off-WhitePeso molecolare:341.774-(5-Methyl-1 H -benzoimidazol-2-yl)-phenylamine
CAS:Purezza:95.0%Colore e forma:Solid, No data available.Peso molecolare:223.27900695800782-(4-Morpholinyl)-1H-benzimidazole
CAS:Purezza:95.0%Colore e forma:Solid, White powderPeso molecolare:203.2449951171875Ref: 10-F311802
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta100mg120,00€250mg180,00€5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:329.4200134277344Ref: 10-F448255
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta25g28,00€100gPrezzo su richiesta500gPrezzo su richiesta
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