Benznidazole

CAS: 22994-85-0

Rif. TR-B197925

Informazioni sul prodotto

• Nome: Benznidazole
• Sinonimi: N-benzyl-2-(2-nitroimidazol-1-yl)acetamide, 1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-, 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide, Benznidazol, Benzonidazol, Benzonidazole, Imidazole-1-acetamide, N-benzyl-2-nitro-, N-Benzyl-2-nitroimidazol-1-yl-acetamide, N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide, N-benzyl-2-nitro-1H-imidazole-1-acetamide, NSC 299972, Radanil, Ro 07-1051, Ro 71051, Rochagan
• CAS: 22994-85-0

Descrizione

Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.
References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 260.25
• Formula: C₁₂H₁₂N₄O₃
• Colore/Forma: Neat
• InChI: InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
• SMILES: O=C(Cn1ccnc1[N+](=O)[O-])NCc1ccccc1