Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8898 prodotti di "Derivati delle Purine e Pirimidine"
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Mono-POC Tenofovir 6-Isopropyl Carbamate (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Very Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Formula:C18H28N5O9PColore e forma:White SolidPeso molecolare:489.42Caffeine Citrate
CAS:<p>Applications Caffeine citrate (Cafcit) is a citrate salt of Caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of Caffeine. Caffeine citrate is typically only used to treat severe migraines.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Grillon, C., et al.: Clin. Neurophysiol., 114, 1557 (2003); Duangdao, D., et al.: Behav. Brain Res., 205, 1 (2009);<br></p>Formula:C8H10N4O2·C6H8O7Colore e forma:WhitePeso molecolare:386.31Almotriptan Dimer Impurity
CAS:Formula:C30H41N5O2SColore e forma:Off White SolidPeso molecolare:535.74nPOC-POC Tenofovir Fumarate(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Formula:C19H30N5O10P·C4H4O4Colore e forma:White To Off-WhitePeso molecolare:635.51rac-Clopidogrel Carboxylic Acid Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications rac-Clopidogrel Carboxylic Acid Hydrochloride is a salt metabolite of rac-Clopidogrel.<br></p>Formula:C15H15Cl2NO2SColore e forma:NeatPeso molecolare:344.261-Methyl-1,4-dihydronicotinamide
CAS:Prodotto controllato<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 1-Methyl-1,4-dihydronicotinamide (cas# 17750-23-1) is a compound useful in organic synthesis.<br></p>Formula:C7H10N2OColore e forma:NeatPeso molecolare:138.171-(6-Amino-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide
CAS:Prodotto controllatoFormula:C10H10N8OColore e forma:NeatPeso molecolare:258.241-Nitroso-3,5-dimethyladamantane
CAS:Prodotto controllatoFormula:C12H19NOColore e forma:NeatPeso molecolare:193.285Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate
Prodotto controllato<p>Applications Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate, is an impurity in the synthesis of Febuxostat n-Butyl Isomer (F229035).<br></p>Formula:C18H20N2O3SColore e forma:NeatPeso molecolare:344.435-Hydroxymethyl-N,N-dimethyltryptamine
CAS:Prodotto controllato<p>Applications Degradation product of Sumatriptan Succinate (S810000).<br>References Xu, X. et al.: J. Pharmaceut. Biomed. 367, 26 (2001)<br></p>Formula:C13H18N2OColore e forma:WhitePeso molecolare:218.29p-Chlorophenylcyanoguanidine
CAS:Prodotto controllato<p>Impurity Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine)<br>Applications Halo-aryl substituted guanidine derivative used in the preparation of antimalarial agents. Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine).<br>References Warner, V. et al.: J. Pharmac. Sci., 66, 418 (1977); Das, A. et al.: Ind. Drugs, 20, 19 (1980);<br></p>Formula:C8H7ClN4Colore e forma:NeatPeso molecolare:194.62N-(5-Aminopentyl) Methotrexate Amide
CAS:Prodotto controllato<p>Applications The 5-aminopentyl amide derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Fan, J. et al.: J. Biol. Chem., 266, 14862 (1991);<br></p>Formula:C25H34N10O4Colore e forma:NeatPeso molecolare:538.6(N,N-Dimethyl-1-butanamine) Zolmitriptan Dimer
CAS:Prodotto controllato<p>Impurity Zolmitriptan USP Related Compound F<br>Stability Hygroscopic<br>Applications (N,N-Dimethyl-1-butanamine) Zolmitriptan Dimer (Zolmitriptan USP Related Compound F) is an impurity from the synthesis of Zolmitriptan (Z639000). Zolmitriptan is a Serotonin 5HTID-receptor agonist.<br>References Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995), Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996), Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)<br></p>Formula:C38H53N7O4Purezza:>90%Colore e forma:NeatPeso molecolare:671.872-Oxo Clopidogrel-13C,d3 Hydrochloride(Mixture of Diastereomers)
CAS:Prodotto controllatoFormula:C1513CH14D3Cl2NO3SColore e forma:NeatPeso molecolare:378.29Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir (T018500) impurity.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Formula:C20H33N6O9PColore e forma:NeatPeso molecolare:532.48Alphenal
CAS:Prodotto controllato<p>Applications Barbituric Acid (B118650) derivative with anti-convulsive properties. Controlled Substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carissime, M. et al.: Farmac. Edi. Sci., 17, 390 (1962); Harvey, D.J. et al.: Drug. Metab. Disp., 5, 527 (1977);<br></p>Formula:C13H12N2O3Colore e forma:NeatPeso molecolare:244.25Diethyl p-Toluenesulfonyloxymethylphosphonate
CAS:Prodotto controllato<p>Applications Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C12H19O6PSColore e forma:NeatPeso molecolare:322.312-Pyrimidinemethanamine
CAS:Prodotto controllato<p>Applications 2-Pyrimidinemethanamine (cas# 75985-45-4) is a useful research chemical.<br></p>Formula:C5H7N3Colore e forma:NeatPeso molecolare:109.131-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide Formate Salt
CAS:Prodotto controllatoFormula:C25H33N5O4S2·CH2O2Colore e forma:NeatPeso molecolare:531.694603Febuxostat Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Febuxostat (F229000), a novel nonpurine selective inhibitor of Xanthin Oxidase.<br>References Grabowski, B., et al.: J. Clin. Pharmacol., 51, 189 (2011); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C22H24N2O9SColore e forma:Off White PowderPeso molecolare:492.50
