Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8901 prodotti di "Derivati delle Purine e Pirimidine"
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Pemetrexed L-Glutamic Acid Trisodium Salt (~90%)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Pemetrexed L-Glutamic acid is an impurity of Pemetrexed (P219500). Pemetrexed impurity D.<br></p>Formula:C25H25N6O9·3NaPurezza:~90%Colore e forma:NeatPeso molecolare:622.472-Oxo Clopidogrel-13C,d3 Hydrochloride(Mixture of Diastereomers)
CAS:Prodotto controllatoFormula:C1513CH14D3Cl2NO3SColore e forma:NeatPeso molecolare:378.293-Descyano Febuxostat Ethyl Ester
CAS:Prodotto controllato<p>Applications 3-Descyano Febuxostat Ethyl Ester is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C17H21NO3SColore e forma:NeatPeso molecolare:319.422-Hydroxy-N-(pyridin-4-yl)butanamide
CAS:Prodotto controllato<p>Applications 2-Hydroxy-N-(pyridin-4-yl)butanamide is a useful synthetic intermediate.<br></p>Formula:C9H12N2O2Colore e forma:NeatPeso molecolare:180.2Tenofovir Dimer Triethylammonium Salt
CAS:Prodotto controllato<p>Stability Very Hygroscopic<br>Applications Tenofovir Dimer is a dimer of Tenofovir (T018500). Tenofovir is a reverse transcriptase inhibitor. Used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C30H56N12O7P2Colore e forma:NeatPeso molecolare:758.79nPOC-POC Tenofovir(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications An impurity of Tenofovir (T018500(P)). Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Formula:C19H30N5O10PColore e forma:NeatPeso molecolare:519.44Alphenal
CAS:Prodotto controllato<p>Applications Barbituric Acid (B118650) derivative with anti-convulsive properties. Controlled Substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carissime, M. et al.: Farmac. Edi. Sci., 17, 390 (1962); Harvey, D.J. et al.: Drug. Metab. Disp., 5, 527 (1977);<br></p>Formula:C13H12N2O3Colore e forma:NeatPeso molecolare:244.25Tenofovir Bis(L-alanine Isopropyl Ester) Amide
CAS:Prodotto controllatoFormula:C21H36N7O6PColore e forma:NeatPeso molecolare:513.53Urea-d4
CAS:Prodotto controllato<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986), Aebischer, P., et al.: Nat. Med., 2, 696 (1996), Prakash, S., et al.: Biotechnol. Bioeng., 46, 621 (1995),<br></p>Formula:CD4N2OColore e forma:NeatPeso molecolare:64.085-Amino-4-pyrazolecarboxamide
CAS:Prodotto controllatoFormula:C4H6N4OColore e forma:Off White To Light BrownPeso molecolare:126.117rac-Clopidogrel Carboxylic Acid Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications rac-Clopidogrel Carboxylic Acid Hydrochloride is a salt metabolite of rac-Clopidogrel.<br></p>Formula:C15H15Cl2NO2SColore e forma:NeatPeso molecolare:344.265-Hydroxymethyl-N,N-dimethyltryptamine
CAS:Prodotto controllato<p>Applications Degradation product of Sumatriptan Succinate (S810000).<br>References Xu, X. et al.: J. Pharmaceut. Biomed. 367, 26 (2001)<br></p>Formula:C13H18N2OColore e forma:WhitePeso molecolare:218.29Oseltamivir Acid Methyl Ester Phosphate Salt
CAS:<p>Applications An impurity of the antiviral drug Oseltamivir (O700100). It is a COVID19-related research product.<br></p>Formula:C15H29N2O8PColore e forma:NeatPeso molecolare:396.37(+)-9-deMe-DTBZ
CAS:<p>Applications (+)-9-deMe-DTBZ is a desmethyl derivative of Tetrabenzine (T284000), a dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>Formula:C18H27NO3Colore e forma:NeatPeso molecolare:305.41Methotrexate-d3 (Technical Grade) (100ug/mL in Methanol with 1% 0.1N NaOH)
CAS:Prodotto controllatoFormula:C20H19D3N8O5Colore e forma:Single SolutionPeso molecolare:457.46p-Chlorophenylcyanoguanidine
CAS:Prodotto controllato<p>Impurity Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine)<br>Applications Halo-aryl substituted guanidine derivative used in the preparation of antimalarial agents. Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine).<br>References Warner, V. et al.: J. Pharmac. Sci., 66, 418 (1977); Das, A. et al.: Ind. Drugs, 20, 19 (1980);<br></p>Formula:C8H7ClN4Colore e forma:NeatPeso molecolare:194.62N-Sulfamoylethyl Naratriptan Pyridinium Chloride
CAS:Prodotto controllato<p>Impurity Naratriptan Impurity F<br>Stability Hygroscopic<br>Applications 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium Chloride is an impurity of Naratriptan (N378730).<br></p>Formula:C20H27ClN4O4S2Colore e forma:NeatPeso molecolare:487.046-Oxo-(S,S)-Palonosetron (~90%)
CAS:Prodotto controllato<p>Applications 6-Oxo-(S,S)-Palonosetron is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Formula:C19H22N2O2Purezza:~90%Colore e forma:NeatPeso molecolare:310.39D-Alanine Isopropyl Ester Hydrochloride
CAS:Prodotto controllato<p>Applications D-Alanine Isopropyl Ester Hydrochloride is a chiral reagent used in the synthesis of nucleotide prodrugs such as (PSI-7977) for the treatment of hepatitis C. Also used in the preparation of synthetic sweeteners.<br>References Sofia, M. et al.: J. Med. Chem., 53, 7202 (2010); Mazur, R. et al.: J. Med. Chem., 16, 1284 (1973);<br></p>Formula:C6H14ClNO2Purezza:~90%Colore e forma:NeatPeso molecolare:167.63Valbenazine (~90% Purity)
CAS:Prodotto controllato<p>Applications Valbenzine is a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia.<br>References O'Brien, C. et al.: Movement Dis., 30, 1681 (2015);<br></p>Formula:C24H38N2O4Purezza:~90%Colore e forma:NeatPeso molecolare:418.57
