Steroidi e Derivati
Gli steroidi sono composti organici con una struttura a quattro anelli fusi, nota come nucleo steroideo. Questo nucleo può essere legato a vari gruppi funzionali che ne modificano le proprietà e le funzioni biologiche. Gli steroidi svolgono un ruolo chiave nella regolazione dei processi metabolici e ormonali. Sono utilizzati in medicina per il trattamento di disturbi infiammatori, malattie autoimmuni e squilibri ormonali. Inoltre, alcuni derivati degli steroidi possiedono potenti proprietà antinfiammatorie, come i corticosteroidi. In terapie specifiche, vengono impiegati per ridurre l’infiammazione e controllare il dolore in diverse patologie.
Presso CymitQuimica, offriamo una varietà di steroidi e loro derivati per la ricerca e lo sviluppo farmaceutico.
Trovati 4967 prodotti di "Steroidi e Derivati"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
6-Hydroxymethyl Exemestane
CAS:Prodotto controllato<p>Applications A potential metabolite of Exemestane (E957000).<br>References Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formula:C20H24O3Colore e forma:NeatPeso molecolare:312.40Desisobutyryl Ciclesonide
CAS:Prodotto controllato<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formula:C28H38O6Colore e forma:White To Off-WhitePeso molecolare:470.601,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS:<p>Stability Hygroscopic<br>Applications A degradation product of Betamethasone (B327000).<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Formula:C28H39FO7Colore e forma:NeatPeso molecolare:506.6011b-Hydroxy Etiocholanolone
CAS:Prodotto controllato<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>Formula:C19H30O3Colore e forma:White To Off-WhitePeso molecolare:306.446-Oxo Boldione
CAS:Prodotto controllato<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formula:C19H22O3Colore e forma:Off-White To Light YellowPeso molecolare:298.38Estrone-2,4-d2
CAS:Prodotto controllato<p>Applications Estrone-2,4-d2 (CAS# 350820-16-5) is a useful isotopically labeled research compound.<br></p>Formula:C182H2H20O2Colore e forma:NeatPeso molecolare:272.38(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS:Prodotto controllato<p>Applications Glucocorticoid.<br></p>Formula:C22H28O4Colore e forma:NeatPeso molecolare:356.46Testosterone-16,16,17-d3 Benzoate
CAS:Prodotto controllatoFormula:C26H29D3O3Colore e forma:NeatPeso molecolare:395.5617a-Hydroxy-17a-methyl-D-homoandrost-4-ene-3,17-dione
CAS:Prodotto controllatoFormula:C21H30O3Colore e forma:NeatPeso molecolare:330.46δ6-Fulvestrant
CAS:Prodotto controllato<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>Formula:C32H45F5O3SColore e forma:NeatPeso molecolare:604.752,5-Bis(trifluoromethyl)aniline
CAS:Prodotto controllato<p>Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).<br>References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);<br></p>Formula:C8H5F6NColore e forma:ColourlessPeso molecolare:229.12Atorvastatin-d5 tert-Butyl Ester
CAS:Prodotto controllato<p>Applications Atorvastatin-d5 tert-Butyl Ester is the labeled analogue of Atorvastatin tert-Butyl Ester (A791740), an impurity arising in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C37H38D5FN2O5Colore e forma:NeatPeso molecolare:619.781-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
CAS:Prodotto controllato<p>Applications 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one is an antioxidant and also has anti cancer effects on human breast cancer MCF-7 cells and Hep3B human hepatocellular carcinoma cells.<br>References Choi, Eun Jeong, et al.: Mol. Med. Rep., 9(1), 328-332 (2014);Choi, Eun Jeong, et al.: Onco.Lett., 6(6), 1784-1788 (2013);Choi, Eun Jeong, et al.: Inter. J.of Mol. Med., 31(3), 726-730 (2013)<br></p>Formula:C15H14O4Colore e forma:NeatPeso molecolare:258.276b-Chloro-7a-hydroxy-6,7-dihydro Cyproterone Acetate
CAS:Prodotto controllato<p>(1β,2β,6β-7α)-17-(Acetyloxy)-6-chloro-1,2-dihydro-7-hydroxy<br>-3'H-cyclopropa[1,2]pregna-1,4-diene-3,20-dione; 6β-Chloro<br>-1β,2β-dihydro-7α,17-dihydroxy-3'Hcyclopropa[1,2]pregna-1,4-diene-3,20-dione 17-Acetate;<br>Cyproterone Acetate EP Impurity G</p>Formula:C24H31ClO5Colore e forma:NeatPeso molecolare:434.953Digitoxigenin Mono-β-D-digitoxoside
CAS:Prodotto controllatoFormula:C29H44O7Colore e forma:White To Off-WhitePeso molecolare:504.6613β-Ethyl-11-methylenegon-4-en-17-one
CAS:Prodotto controllato<p>Applications Desogestrel intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bergink, E., et al.: J. Steroid Biochem., 14, 175 (1981), Phillips, A., et al.: Contraception, 36, 181 (1987)<br></p>Formula:C20H28OColore e forma:NeatPeso molecolare:284.44a,a,a-Trifluorotoluene
CAS:Prodotto controllato<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Formula:C7H5F3Colore e forma:ColourlessPeso molecolare:146.114'-Nitro-3'-(trifluoromethyl)acetanilide
CAS:<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Formula:C9H7F3N2O3Colore e forma:NeatPeso molecolare:248.166-Deschloro Cyproterone Acetate
CAS:Prodotto controllato<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Formula:C24H30O4Colore e forma:NeatPeso molecolare:382.493Ulipristal
CAS:Prodotto controllato<p>Applications Ulipristal is a selective progesterone receptor modulator. Ulipristal is used as an emergency contraceptive.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>Formula:C28H35NO3Colore e forma:NeatPeso molecolare:433.58[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden-5-one
CAS:Prodotto controllatoFormula:C18H24O4Colore e forma:NeatPeso molecolare:304.38Cholesterol 5α,6α-Epoxide
CAS:Prodotto controllato<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Formula:C27H46O2Colore e forma:NeatPeso molecolare:402.6525-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether
CAS:<p>Applications Vitamin D3 (V676045) analog.<br>References Roy, A., et al.: Steroids, 60, 530 (1995);<br></p>Formula:C40H65N3O4SColore e forma:NeatPeso molecolare:684.03Testosterone Cypionate-d3 (1 mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C27D3H37O3Colore e forma:Single SolutionPeso molecolare:415.62Testosterone 17-O-Acetate-d3 (1mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C21H27D3O3Colore e forma:ColourlessPeso molecolare:333.4817α-Methyl-4-[(phenylthio)methyl]testosterone
CAS:Prodotto controllato<p>Applications Testosterone (T155000) derivative.<br></p>Formula:C27H36O2SColore e forma:NeatPeso molecolare:424.64Finasteride Carboxaldehyde
CAS:Prodotto controllato<p>Applications A metabolite of Finasteride (F342000) in human bile (M2 metabolite).<br>References Faller, B., et al.: Biochemistry, 32, 5705 (1993), Carlin, J.R., Drug Metab. Dispos., 25, 100 (1997), Bergman, E., et al.: Eur. J. Pharm. Sci., 29, 205 (2006),<br></p>Formula:C23H34N2O3Colore e forma:NeatPeso molecolare:386.5316α-Hydroxypregna-4,9(11)-diene-3,20-dione
Prodotto controllato<p>Applications 16α-Hydroxypregna-4,9(11)-diene-3,20-dione is an intermediate in the synthesis of 16-Hydroxycorticosterone 20-Hydroxy-21-Acid (H918430), an oxidized derivative of corticosterone (C695700).<br>References Allen, G.R., et al.: J. Am. Chem. Soc., 81, 4968 (1959);<br></p>Formula:C21H28O3Colore e forma:NeatPeso molecolare:328.45Boldione (1 mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C19H24O2Colore e forma:Single SolutionPeso molecolare:284.39Prednisolone 21-Sulfate Sodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Prednisolone 21-Sulfate is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Formula:C21H27NaO8SColore e forma:NeatPeso molecolare:462.49Prednicarbate
CAS:Prodotto controllato<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Formula:C27H36O8Colore e forma:Off-WhitePeso molecolare:488.5717-Hydroxypregn-5-ene-3,20-dione
CAS:Prodotto controllato<p>Applications 17-Hydroxypregn-5-ene-3,20-dione is used in the synthesis of physiologically active steroid esters and spirolactones that functions as potential aldosterone antagonists.<br>References Seletskii, B. M., et al.: Croat. Chem. Acta. , 58, 699 (1986)<br></p>Formula:C21H30O3Colore e forma:NeatPeso molecolare:330.46(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (Bimatoprost Impurity)
CAS:Prodotto controllatoFormula:C18H24O4Colore e forma:NeatPeso molecolare:304.3810b-Hydroxy D-(-)-Norgestrel
CAS:<p>Applications 10β-Hydroxy D-(-)-Norgestrel is an impurity of Levonorgestrel (N689510).<br>References Gorog, S. et al.: J. Pharmac. Biomed. Anal., 14, 85 (1995); Berta, R. et al.: J. Pharmac. Biomed. Anal., 54, 458 (2011); Choudhary, M. I. et al.: Nat. Prod. Res., 20, 1074 (2006);<br></p>Formula:C21H28O3Colore e forma:White To Off-WhitePeso molecolare:328.44517α,21-Dideoxy-6α,9α-Difluoroprednisolone
CAS:Prodotto controllato<p>Applications 17α,21-Dideoxy-6α,9α-Difluoroprednisolone is an impurity of the drug Difluprednate (D445925). Difluprednate is a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002); Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003); Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005)<br></p>Formula:C20H24F2O4Colore e forma:NeatPeso molecolare:366.4Dexamethasone Acetate Impurity E
CAS:<p>Applications Dexamethasone Acetate Impurity E is a pregn-4-ene derivative used in the preparation of antiallergic and antiinflammatory drugs.<br>References Nedelec, L., et al.: Ger. Offen. (1978)<br></p>Formula:C24H33FO6Colore e forma:NeatPeso molecolare:436.51Gestonorone Capronate
CAS:Prodotto controllatoFormula:C26H38O4Colore e forma:NeatPeso molecolare:414.583-Aminobenzotrifluoride
CAS:Prodotto controllato<p>Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)<br></p>Formula:C7H6F3NColore e forma:YellowPeso molecolare:161.1218-Methyl Ethynyl Estradiol
CAS:Prodotto controllatoFormula:C21H26O2Colore e forma:NeatPeso molecolare:310.429921-Butyryloxy Budesonide
<p>Applications 21-Butyryloxy Budesonide is a derivative of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979); Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980); Clissold, S.P., et al.: Drugs, 28, 485 (1984)<br></p>Formula:C29H40O7Colore e forma:NeatPeso molecolare:500.62D-Homoanalog of Triamcinolone
CAS:Prodotto controllato<p>Applications D-Homoanalog of Triamcinolone is a rearrangement product of the drug triamcinolone, an anti-inflammatory drug.<br>References Delaney, E. J.; et al.: Steroids, 59, 196 (1994)<br></p>Formula:C21H27FO6Colore e forma:NeatPeso molecolare:394.436α-Hydroxy Gestrinone Glucuronide
CAS:Prodotto controllatoFormula:C27H32O9Colore e forma:Light YellowPeso molecolare:500.54(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
CAS:Prodotto controllato<p>Applications (16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Formula:C25H32O6Colore e forma:NeatPeso molecolare:428.52(E/Z)-17-Deacetylnorgestimate
CAS:Prodotto controllatoFormula:C21H29NO2Colore e forma:NeatPeso molecolare:327.46δ6-Gestodene
Prodotto controllato<p>Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);<br></p>Formula:C21H24O2Colore e forma:NeatPeso molecolare:308.416α-Hydroxy Testosterone-d3
CAS:Prodotto controllatoFormula:C19H25D3O3Colore e forma:NeatPeso molecolare:307.443β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C21H30O2Colore e forma:Single SolutionPeso molecolare:314.46Testosterone (1 mg/mL in Acetonitrile)
CAS:Prodotto controllatoFormula:C19H28O2Colore e forma:ColourlessPeso molecolare:288.429-Chloro Triamcinolone Acetonide 21-Acetate
CAS:Prodotto controllato<p>Applications Triamcinolone Acetonide (T767165) impurity.<br></p>Formula:C26H33ClO7Colore e forma:WhitePeso molecolare:492.989Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS:Formula:C22H32FO11PS•xNaColore e forma:NeatPeso molecolare:554.522298Equilin-d4
CAS:Prodotto controllatoFormula:C182H4H16O2Colore e forma:White SolidPeso molecolare:272.37Dexamethasone b-D-Glucuronide Sodium (>90%)
CAS:Prodotto controllato<p>Applications Sodium salt of Dexamethasone β-D-Glucuronide is a potential prodrug for colonic delivery of the antiinflammatory corticosteroid Dexamethasone.<br>References Fotsis, T., et al.: J. Steroid Biochem., 14, 457 (1981), Choi, M., et al.: Steroids, 65, 54 (2000); Haeberlin, B. et al.: Pharm Res., 10, 1553 (1993);<br></p>Formula:C28H36FNaO11Colore e forma:NeatPeso molecolare:590.57Betamethasone 21-Acetate
CAS:Prodotto controllato<p>Applications Betamethasone acetate (BA) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),<br></p>Formula:C24H31FO6Colore e forma:WhitePeso molecolare:434.50Estradiol 3-Propyl Ether
CAS:Prodotto controllatoFormula:C21H30O2Colore e forma:NeatPeso molecolare:314.46Betamethasone 17-Propionate 21-Mesylate
CAS:<p>Impurity Clobetasol Propionate EP Impurity I<br>Stability Hygroscopic<br>Applications Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.<br>References Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);<br></p>Formula:C26H35FO8SColore e forma:NeatPeso molecolare:526.61Testosterone Oleate
CAS:Prodotto controllatoFormula:C37H60O3Colore e forma:NeatPeso molecolare:552.8718-Methyl Mestranol
CAS:Prodotto controllato<p>Applications Mestranol (M258755) derivative. It is used as contraceptive.<br>References Cullen, L.F., et al.: J. Pharma. Sci., 57, 1857 (1968),<br></p>Formula:C22H28O2Colore e forma:NeatPeso molecolare:324.46(3(α))-Allopregnanolone 3-(β)-DGlucuronide
CAS:Prodotto controllato<p>Applications (3α)-Allopregnanolone 3-β-D-Glucuronide is the glucuronide conjugate of (3α)-Allopregnanolone (A547100), metabolite of progesterone and potent positive modulator of GABAA receptors.<br>References Martin, F. et al.: LJ Steroid Biochem., 6, 1339 (1975); Lin, M.T. et al.: Steroids, 32, 547 (1978);<br></p>Formula:C27H42O8Colore e forma:NeatPeso molecolare:494.623-epi-25-Hydroxy Vitamin D3
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3 (C125700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sakaki, T., et al.: Eur. J. Biochem., 267, 6158 (2000), Kamao, M., et al.: J. Biol. Chem., 278, 1463 (2003),<br></p>Formula:C27H44O2Colore e forma:NeatPeso molecolare:400.642-Hydroxy Estradiol 6-N3-Adenine
CAS:Prodotto controllato<p>Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Formula:C23H27N5O3Colore e forma:NeatPeso molecolare:421.496α-Hydroxy Budesonide
CAS:Prodotto controllatoFormula:C26H34O7Colore e forma:NeatPeso molecolare:458.549α-Bromobudesonide
CAS:Prodotto controllato<p>Impurity Budesonide EP Impurity J<br>Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Formula:C25H33BrO6Colore e forma:NeatPeso molecolare:509.434β-Hydroxy Cholesterol
CAS:Prodotto controllato<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Formula:C27H46O2Colore e forma:White To Light BeigePeso molecolare:402.65b-Estradiol 17-Acetate
CAS:Prodotto controllato<p>Applications Protected Estradiol. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Formula:C20H26O3Colore e forma:NeatPeso molecolare:314.42(3E)-17-Deacetylnorgestimate
CAS:<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Formula:C21H29NO2Colore e forma:Off-WhitePeso molecolare:327.46Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Formula:C33H33FN2O6Colore e forma:NeatPeso molecolare:572.626b-Methyl Fluorometholone
CAS:Prodotto controllato<p>Stability Not stable in Acidic or basic condition<br>Applications 6β-Methyl Fluorometholone is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Formula:C22H29FO4Colore e forma:NeatPeso molecolare:376.46Deflazacort-d3 (Major)
CAS:Prodotto controllatoFormula:C25H28D3NO6Colore e forma:NeatPeso molecolare:444.54(11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione(Deflazacort Impurity)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications (11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, is an impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus.<br>References Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),<br></p>Formula:C27H33NO7Colore e forma:NeatPeso molecolare:483.55Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride
CAS:Prodotto controllato<p>Applications An impurity of Finasteride (F342000).<br></p>Formula:C21H31NO2Colore e forma:NeatPeso molecolare:329.484-Methylestrone
CAS:Prodotto controllato<p>Applications 4-Methylestrone is an intermediate in the synthesis of 4-substituted estrone and estradiol derivatives with inhibitory activities towards steroid sulfatase as a target for therapeutic intervention of treating breast cancer.<br>References Numazawa, M., et al.: J. Steroid. Biochem. Molec. Biol., 96, 51 (2005);<br></p>Formula:C19H24O2Colore e forma:NeatPeso molecolare:284.39a-Epoxyabiraterone Acetate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Formula:C26H33NO3Colore e forma:NeatPeso molecolare:407.55Estratetraenol
CAS:Prodotto controllato<p>Applications A steroid produced by females having pheromone activities.<br>References Kotiyan, P., et al.: J. Pharm. Biomed. Anal., 22, 667 (2000), Bensafi, M., et al.: Behaviour. Brain Res., 152, 11 (2004), Zhu, B., et al.: Endocrinol., 147, 4132 (2006), Bellavance, E., et al.: J. Med. Chem., 52, 7488 (2009),<br></p>Formula:C18H22OColore e forma:NeatPeso molecolare:254.3720β-Dihydrocortisone
CAS:Prodotto controllato<p>Applications 20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Reach, G., et. al.: Steroids, 30, 621 (1977); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)<br></p>Formula:C21H30O5Colore e forma:NeatPeso molecolare:362.466-Dehydro Nandrolone Acetate
CAS:Prodotto controllatoFormula:C20H26O3Colore e forma:NeatPeso molecolare:314.42Tetrahydrocortisol 21-Acetate
CAS:Prodotto controllato<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Formula:C23H36O6Colore e forma:NeatPeso molecolare:408.537-(Desacetothioxy)-7-acetodithioperoxy-spironolactone
Prodotto controllatoFormula:C24H32O4S2Colore e forma:NeatPeso molecolare:448.6423-Hydroxybudesonide
CAS:Prodotto controllato<p>Applications 23-Hydroxybudesonide is an metabolite of budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Edsbaecker, S., et al.: Drug. Metabol. Dispostion., 15, 403 (1987); Moore, C.D., et al.: Drug. Metabolism. Disposition., 41, 379 (2013);<br></p>Formula:C25H34O7Colore e forma:NeatPeso molecolare:446.5315-Keto Latanoprost
CAS:<p>Applications 15-Keto Latanoprost is a metabolite of Latanoprost (L177280).<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999),<br></p>Formula:C23H30O5Colore e forma:NeatPeso molecolare:386.48Fluocinolone Acetonide-13C3
CAS:Prodotto controllatoFormula:C2113C3H30F2O6Colore e forma:NeatPeso molecolare:455.4713-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (~90%) (Levo Norgestrel Impurity)
CAS:Prodotto controllato<p>Impurity Levonorgestrel EP Impurity D<br>Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Formula:C21H30OColore e forma:NeatPeso molecolare:298.4625-Hydroxy Cholesterol-d6
CAS:Prodotto controllato<p>Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>Formula:C272H6H40O2Colore e forma:NeatPeso molecolare:408.69Cortisol-D4 21-Sulfate Potassium Salt
CAS:Prodotto controllato<p>Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Formula:C21H25D4KO8SColore e forma:NeatPeso molecolare:484.641,2-Dihydro Triamcinolone
CAS:Prodotto controllato<p>Applications 1,2-Dihydro Triamcinolone is a derivative of Triamcinolone (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982);<br></p>Formula:C21H29FO6Colore e forma:NeatPeso molecolare:396.45Betamethasone 21-Phosphate Biotin (>85%)
Prodotto controllatoFormula:C34H49FN3O10PSPurezza:>85%Colore e forma:NeatPeso molecolare:741.81Tixocortol
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.<br>References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),<br></p>Formula:C21H30O4SColore e forma:NeatPeso molecolare:378.532,2-Dibromo-1-(4-fluorophenyl)-2-phenylethanone
Prodotto controllatoFormula:C14H9Br2FOColore e forma:NeatPeso molecolare:372.03(11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
CAS:Prodotto controllato<p>Applications (11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione is a derivative of Dexamethasone (D298800), an anti-inflammatory glucocorticoid.<br>References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),<br></p>Formula:C22H27FO4Colore e forma:WhitePeso molecolare:374.45Dexamethasone 17-Propionate
CAS:Prodotto controllato<p>Applications A Dexamethasone Dipropionate metabolite.<br>References Miyachi, Y., et al.: Steroids, 52, 137 (1988), Soh H., et al.: Brit. J. dermatol., 125, 73 (1991), Civiale, C., et al.: J. Ocul. Pharmacol., Thera., 20, 75 (2004),<br></p>Formula:C25H33FO6Colore e forma:NeatPeso molecolare:448.526a-9-Difluoroprednisolone-17-Carboxylate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 6α-9-Difluoroprednisolone-17-Carboxylate is an impurity of 6α,9α-Difluoroprednisolone (D446290), shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Formula:C20H24F2O5Colore e forma:NeatPeso molecolare:382.4N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Prodotto controllato<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Formula:C25H38N2O2Colore e forma:NeatPeso molecolare:398.58Bexarotene-13C4
CAS:Prodotto controllato<p>Applications Labelled Bexarotene (B336750). Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.<br>References Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994), Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996), Mukherjee, R., et al.: Nature, 386, 407 (1997), Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)<br></p>Formula:C4C20H28O2Colore e forma:NeatPeso molecolare:352.45Testosterone-d8
CAS:Prodotto controllato<p>Applications Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Controlled substance (anabolic steroid). Androgen.<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Formula:C19H20D8O2Colore e forma:White To Off-WhitePeso molecolare:296.47Estriol 3,16a,17b-Triacetate
CAS:Prodotto controllato<p>Applications Estriol 3,16α,17β-Triacetate is a triacetate derivative of Estriol (E888960) with contraceptive activity.<br>References Wotiz, H.H., et al.: J. Reprod. Fertil., 26, 363 (1971)<br></p>Formula:C24H30O6Colore e forma:NeatPeso molecolare:414.494-Hydroxy Estradiol 1-N3-Adenine
CAS:Prodotto controllato<p>Applications 4-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Formula:C23H27N5O3Colore e forma:NeatPeso molecolare:421.496b-Chloro-17-acetoxy Progesterone
CAS:Prodotto controllato<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Formula:C23H31ClO4Colore e forma:NeatPeso molecolare:406.943Equilenin-d3
CAS:Prodotto controllato<p>Applications Isotope labelled Equilenin (E592400), which is a naturally occuring estrogenic steroidal hormone (1,2) isolated from urine of pregnant mares (3). Not found in human urine. Component of conjugated estrogenic hormones. Estrogen. This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Corbellini, A. et L.: Farmaco Sci. 1964 Nov;19:913-22.2. Stein, R. et al.: Tetrahedron 1970 Apr;26(8):1917-33.<br></p>Formula:C182H3H15O2Colore e forma:White To Light BrownPeso molecolare:269.352-Hydroxy Atorvastatin Lactone
CAS:Prodotto controllato<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Formula:C33H33FN2O5Colore e forma:Off White SolidPeso molecolare:556.62
![[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD458310.webp&w=3840&q=75)
![17α-Methyl-4-[(phenylthio)methyl]testosterone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM324800.webp&w=3840&q=75)
![(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (B…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH294735.webp&w=3840&q=75)
![(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FE890583.webp&w=3840&q=75)
![(11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione(Deflazaco…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB400605.webp&w=3840&q=75)
![Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD289025.webp&w=3840&q=75)
