Steroidi e Derivati
Gli steroidi sono composti organici con una struttura a quattro anelli fusi, nota come nucleo steroideo. Questo nucleo può essere legato a vari gruppi funzionali che ne modificano le proprietà e le funzioni biologiche. Gli steroidi svolgono un ruolo chiave nella regolazione dei processi metabolici e ormonali. Sono utilizzati in medicina per il trattamento di disturbi infiammatori, malattie autoimmuni e squilibri ormonali. Inoltre, alcuni derivati degli steroidi possiedono potenti proprietà antinfiammatorie, come i corticosteroidi. In terapie specifiche, vengono impiegati per ridurre l’infiammazione e controllare il dolore in diverse patologie.
Presso CymitQuimica, offriamo una varietà di steroidi e loro derivati per la ricerca e lo sviluppo farmaceutico.
Trovati 4974 prodotti di "Steroidi e Derivati"
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6-Dehydro Nandrolone Acetate
CAS:Prodotto controllatoFormula:C20H26O3Colore e forma:NeatPeso molecolare:314.4211b-Hydroxy Etiocholanolone
CAS:Prodotto controllato<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>Formula:C19H30O3Colore e forma:White To Off-WhitePeso molecolare:306.446b-Hydroxylevonorgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity H<br>Applications 6β-Hydroxylevonorgestrel (Levonorgestrel EP Impurity H) is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive.<br>References Hu. S.H., et al.: Steroids., 63, 88 (1998); Nash, H.A., et al.: J. Pharma. Sci., 93, 2420 (2004); Choudhary, M.I., et al.: Natural. Prod. Res., 20, 1074 (2006);<br></p>Formula:C21H28O3Colore e forma:White To Light YellowPeso molecolare:328.45Digitoxigenin Mono-β-D-digitoxoside
CAS:Prodotto controllatoFormula:C29H44O7Colore e forma:White To Off-WhitePeso molecolare:504.66Betamethasone 17-Propionate 21-Mesylate
CAS:<p>Impurity Clobetasol Propionate EP Impurity I<br>Stability Hygroscopic<br>Applications Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.<br>References Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);<br></p>Formula:C26H35FO8SColore e forma:NeatPeso molecolare:526.61Testosterone Oleate
CAS:Prodotto controllatoFormula:C37H60O3Colore e forma:NeatPeso molecolare:552.87Tasimelteon
CAS:<p>Applications Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.<br>References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014);<br></p>Formula:C15H19NO2Colore e forma:NeatPeso molecolare:245.31694β-Hydroxy Cholesterol
CAS:Prodotto controllato<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Formula:C27H46O2Colore e forma:White To Light BeigePeso molecolare:402.65(3E)-17-Deacetylnorgestimate
CAS:<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Formula:C21H29NO2Colore e forma:Off-WhitePeso molecolare:327.462,5-Bis(trifluoromethyl)aniline
CAS:Prodotto controllato<p>Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).<br>References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);<br></p>Formula:C8H5F6NColore e forma:ColourlessPeso molecolare:229.12Cholesterol 5α,6α-Epoxide
CAS:Prodotto controllato<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Formula:C27H46O2Colore e forma:NeatPeso molecolare:402.6518-Methyl Mestranol
CAS:Prodotto controllato<p>Applications Mestranol (M258755) derivative. It is used as contraceptive.<br>References Cullen, L.F., et al.: J. Pharma. Sci., 57, 1857 (1968),<br></p>Formula:C22H28O2Colore e forma:NeatPeso molecolare:324.46Equilin-d4
CAS:Prodotto controllatoFormula:C182H4H16O2Colore e forma:White SolidPeso molecolare:272.37Desogestrel
CAS:Prodotto controllato<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Formula:C22H30OColore e forma:White To Off-WhitePeso molecolare:310.474-Methylestrone
CAS:Prodotto controllato<p>Applications 4-Methylestrone is an intermediate in the synthesis of 4-substituted estrone and estradiol derivatives with inhibitory activities towards steroid sulfatase as a target for therapeutic intervention of treating breast cancer.<br>References Numazawa, M., et al.: J. Steroid. Biochem. Molec. Biol., 96, 51 (2005);<br></p>Formula:C19H24O2Colore e forma:NeatPeso molecolare:284.391-Dehydro Aldosterone
CAS:Prodotto controllatoFormula:C21H26O5Colore e forma:NeatPeso molecolare:358.43Estrone-2,4-d2
CAS:Prodotto controllato<p>Applications Estrone-2,4-d2 (CAS# 350820-16-5) is a useful isotopically labeled research compound.<br></p>Formula:C182H2H20O2Colore e forma:NeatPeso molecolare:272.381,2-Dihydro Triamcinolone
CAS:Prodotto controllato<p>Applications 1,2-Dihydro Triamcinolone is a derivative of Triamcinolone (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982);<br></p>Formula:C21H29FO6Colore e forma:NeatPeso molecolare:396.45Tixocortol (>90%)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.<br>References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),<br></p>Formula:C21H30O4SColore e forma:NeatPeso molecolare:378.53Estratetraenol
CAS:Prodotto controllato<p>Applications A steroid produced by females having pheromone activities.<br>References Kotiyan, P., et al.: J. Pharm. Biomed. Anal., 22, 667 (2000), Bensafi, M., et al.: Behaviour. Brain Res., 152, 11 (2004), Zhu, B., et al.: Endocrinol., 147, 4132 (2006), Bellavance, E., et al.: J. Med. Chem., 52, 7488 (2009),<br></p>Formula:C18H22OColore e forma:NeatPeso molecolare:254.376α-Hydroxy-21-desacetyl Deflazacort
CAS:Prodotto controllato<p>Applications The minor metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Formula:C23H29NO6Colore e forma:NeatPeso molecolare:415.48Desisobutyryl Ciclesonide
CAS:Prodotto controllato<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formula:C28H38O6Colore e forma:White To Off-WhitePeso molecolare:470.60Dexamethasone 17-Propionate
CAS:Prodotto controllato<p>Applications A Dexamethasone Dipropionate metabolite.<br>References Miyachi, Y., et al.: Steroids, 52, 137 (1988), Soh H., et al.: Brit. J. dermatol., 125, 73 (1991), Civiale, C., et al.: J. Ocul. Pharmacol., Thera., 20, 75 (2004),<br></p>Formula:C25H33FO6Colore e forma:NeatPeso molecolare:448.52(5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one
CAS:Prodotto controllato<p>Applications (5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one is metabolite and impurity of the anabolic steroid Oxandrolone (O845050).<br>References Fragkaki, A.G. et al.: J. Steroid Biochem. Mol. Biol., 115, 44 (2009); Bi, H. et al.: J. Steroid Biochem. Mol. Biol., 42, 533 (1992);<br></p>Formula:C19H28O2Colore e forma:White To Off-WhitePeso molecolare:288.427α-Acetylthio-17α-ethoxymethyl Testosterone
CAS:Prodotto controllatoFormula:C24H36O4SColore e forma:NeatPeso molecolare:420.61N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Prodotto controllato<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Formula:C25H38N2O2Colore e forma:NeatPeso molecolare:398.5817-Hydroxypregn-5-ene-3,20-dione
CAS:Prodotto controllato<p>Applications 17-Hydroxypregn-5-ene-3,20-dione is used in the synthesis of physiologically active steroid esters and spirolactones that functions as potential aldosterone antagonists.<br>References Seletskii, B. M., et al.: Croat. Chem. Acta. , 58, 699 (1986)<br></p>Formula:C21H30O3Colore e forma:NeatPeso molecolare:330.466-Oxo Boldione
CAS:Prodotto controllato<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formula:C19H22O3Colore e forma:Off-White To Light YellowPeso molecolare:298.383-O-Benzyl Estriol
CAS:Prodotto controllato<p>Applications Protected Estriol.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formula:C25H30O3Colore e forma:NeatPeso molecolare:378.5013-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (~90%) (Levo Norgestrel Impurity)
CAS:Prodotto controllato<p>Impurity Levonorgestrel EP Impurity D<br>Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Formula:C21H30OColore e forma:NeatPeso molecolare:298.4625-Hydroxy Cholesterol-d6
CAS:Prodotto controllato<p>Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>Formula:C272H6H40O2Colore e forma:NeatPeso molecolare:408.6920-Hydroxydexamethasone
CAS:Prodotto controllatoFormula:C22H31FO5Colore e forma:NeatPeso molecolare:394.489-Chloro Triamcinolone Acetonide 21-Acetate
CAS:Prodotto controllato<p>Applications Triamcinolone Acetonide (T767165) impurity.<br></p>Formula:C26H33ClO7Colore e forma:WhitePeso molecolare:492.989Testosterone-16,16,17-d3 3-Phenylpropionate
CAS:Prodotto controllato<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>Formula:C28H33D3O3Colore e forma:NeatPeso molecolare:423.609α-Bromobudesonide
CAS:Prodotto controllato<p>Impurity Budesonide EP Impurity J<br>Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Formula:C25H33BrO6Colore e forma:NeatPeso molecolare:509.43Testosterone-16,16,17-d3 17-Decanoate
CAS:Prodotto controllato<p>Applications Testosterone 17-Decanoate-d3, is the labeled analogue of Testosterone 17-Decanoate (T155120), an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants.<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Formula:C292H3H43O3Colore e forma:NeatPeso molecolare:445.69Dexamethasone Oxetanone
CAS:Prodotto controllato<p>Applications Dexamethasone Oxetanone is a potent antiglucocorticoid.<br>References Lamontagne, N., et al.: Endocrinology, 114, 2252 (1984);<br></p>Formula:C22H27FO4Colore e forma:NeatPeso molecolare:374.45Betamethasone 21-Phosphate Biotin (>85%)
Prodotto controllatoFormula:C34H49FN3O10PSPurezza:>85%Colore e forma:NeatPeso molecolare:741.81Ciclesonide-d7
CAS:Prodotto controllato<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formula:C32H37D7O7Colore e forma:NeatPeso molecolare:547.736α-Hydroxy Budesonide
CAS:Prodotto controllatoFormula:C26H34O7Colore e forma:NeatPeso molecolare:458.54E-Ospemifene
CAS:Prodotto controllato<p>Applications E-Ospemifene is the E-isomer of Ospemifene (O703000) and is useful for lowering serum cholesterol. It acts as a antiatherosclerotic and is also estrogen-like.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sodervall, M., et al.: PCT Int. Appl. WO 9942427 A1 19990826. Aug 26, 1999<br></p>Formula:C24H23ClO2Colore e forma:NeatPeso molecolare:378.89Bexarotene-13C4
CAS:Prodotto controllato<p>Applications Labelled Bexarotene (B336750). Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.<br>References Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994), Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996), Mukherjee, R., et al.: Nature, 386, 407 (1997), Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)<br></p>Formula:C4C20H28O2Colore e forma:NeatPeso molecolare:352.4516α-Hydroxypregna-4,9(11)-diene-3,20-dione
Prodotto controllato<p>Applications 16α-Hydroxypregna-4,9(11)-diene-3,20-dione is an intermediate in the synthesis of 16-Hydroxycorticosterone 20-Hydroxy-21-Acid (H918430), an oxidized derivative of corticosterone (C695700).<br>References Allen, G.R., et al.: J. Am. Chem. Soc., 81, 4968 (1959);<br></p>Formula:C21H28O3Colore e forma:NeatPeso molecolare:328.452-Hydroxy-estrone-6-N3-adenine (90%)
CAS:Prodotto controllato<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Formula:C23H25N5O3Purezza:90%Colore e forma:NeatPeso molecolare:419.48(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS:Prodotto controllato<p>Applications Glucocorticoid.<br></p>Formula:C22H28O4Colore e forma:NeatPeso molecolare:356.4617β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS:Prodotto controllato<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Formula:C26H31D3O8Colore e forma:NeatPeso molecolare:477.56a,a,a-Trifluorotoluene
CAS:Prodotto controllato<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Formula:C7H5F3Colore e forma:ColourlessPeso molecolare:146.1117a-Hydroxy-17a-methyl-D-homoandrost-4-ene-3,17-dione
CAS:Prodotto controllatoFormula:C21H30O3Colore e forma:NeatPeso molecolare:330.4617β-Dihydro Equilin-16,16,17-d3
CAS:Prodotto controllato<p>Applications A labelled metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formula:C182H3H17O2Colore e forma:NeatPeso molecolare:271.37
