Nucleosidi e Nucleotidi
I nucleosidi sono composti formati da una base azotata legata a uno zucchero (ribosio o desossiribosio). Quando un gruppo fosfato viene aggiunto al nucleoside, si forma un nucleotide. Questi composti sono fondamentali nella biologia cellulare, poiché i nucleotidi sono i mattoni essenziali del DNA e dell’RNA, responsabili dell’archiviazione e della trasmissione delle informazioni genetiche. I nucleosidi trovano applicazione nel trattamento delle malattie virali, agendo come inibitori della replicazione virale. I nucleotidi, oltre al loro ruolo strutturale negli acidi nucleici, sono coinvolti nei processi energetici, come la sintesi dell’ATP.
Presso CymitQuimica, offriamo un’ampia gamma di nucleosidi e nucleotidi essenziali per la ricerca in biologia molecolare, virologia e farmacologia.
Trovati 3432 prodotti di "Nucleosidi e Nucleotidi"
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N-Carboxybenzyl Gemcitabine
CAS:Prodotto controllato<p>Applications Gemcitabine (G305000) derivative.<br></p>Formula:C17H17F2N3O6Colore e forma:NeatPeso molecolare:397.33ent-Lamivudine
CAS:Prodotto controllato<p>Impurity Lamivudine EP Impurity D<br>Stability Hygroscopic<br>Applications ent-Lamivudine (Lamivudine EP Impurity D) is an enantiomer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.<br>References Pepe, G. et al.: Eur. J. Med. Chem., 31, 775 (1996); Marr, E. et al.: Antiviral Res., 28, 1 (1995); Parikh, U.M. et al.: Antimicrob. Agents Chemother., 49, 1139 (2005);<br></p>Formula:C8H11N3O3SColore e forma:NeatPeso molecolare:229.26β-Decitabine-3',5'-bis(4-chlorobenzoate)
CAS:Prodotto controllatoFormula:C22H18Cl2N4O6Colore e forma:NeatPeso molecolare:505.308Emtricitabine N,N’-Methylene Dimer
Prodotto controllato<p>Applications Emtricitabine N,N’-Methylene Dimer is a derivative compound of Emtricitabine (E525000), a reverse transcriptase inhibitor. It is effective antiviral agent against HIV, and other viruses replicating in a similiar manner. A nucleoside analog structurally related to Lamivudine (L172500).<br>References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)<br></p>Formula:C17H20F2N6O6S2Colore e forma:NeatPeso molecolare:506.53’-O-(5’-Deoxy-α-D-ribofuranosyl) Capecitabine
CAS:Prodotto controllato<p>Applications Capecitabine (C175650) impurity.<br></p>Formula:C20H30FN3O9Colore e forma:NeatPeso molecolare:475.472-Amino-5-nitroso-4,6-pyrimidinediol
CAS:Prodotto controllatoFormula:C4H4N4O3Colore e forma:NeatPeso molecolare:156.12-epi-Emtricitabine
CAS:<p>Applications The 2-epi-enantiomer analogue of (-)-Emtricitabine (E525000) evaluated against HIV-1 in human peripheral blood mononuclear (PBM) cells.<br>References Jeong, L.S., et al.: J. Med. Chem., 36, 2627 (1993),<br></p>Formula:C8H10FN3O3SColore e forma:Off White SolidPeso molecolare:247.25Emtricitabine Triphosphate Triethylammonium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Emtricitabine Triphosphate Triethylammonium Salt is a metabolite of (-)-Emtricitabine (E525000).<br>References Barditch-Crovo, P., et al.: Antimicrob. Agents Chemother., 45, 2733 (2001); Ray, A., et al.: Antivir .Ther., 10, 451 (2005); Borroto-Esoda, K., et al.: Antivir. Ther., 11, 377 (2006)<br></p>Formula:C8H13FN3O12P3S•3(C6H15N)Colore e forma:NeatPeso molecolare:487.191011932’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine
CAS:Prodotto controllato<p>Impurity Capecitabine 2-O-BDR Impurity (USP)<br>Stability Hygroscopic<br>Applications Capecitabine (C175650) impurity. Capecitabine 2-O-BDR Impurity (USP).<br></p>Formula:C20H30FN3O9Colore e forma:NeatPeso molecolare:475.472’-Deoxy-2’-fluoro Cytidine
CAS:Prodotto controllato<p>Applications 2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and spread.<br>References Stuyver, L.J. et al.: Antimicrob. Agents Chemother., 48, 651 (2004); Bajramovic, J.J. et al.: Antiomicrob. Agents Chemother., 48, 1422 (2004);<br></p>Formula:C9H12FN3O4Colore e forma:NeatPeso molecolare:245.212’,3’,5’-Tri-O-acetylinosine
CAS:Prodotto controllato<p>Stability Freezer<br>Applications An intermediate used for the synthesis of 6-substituted purine ribosides.<br></p>Formula:C16H18N4O8Colore e forma:NeatPeso molecolare:394.34Azathioprine-13C4
CAS:Prodotto controllato<p>Applications Labelled Azathioprine (A803350). An immunosuppressive antimetabolite. Also active as disease modifying antirheumatic drug (DMARD).<br>References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979), Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979), Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987), Sandborn, W.J., et al.: : Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998,)<br></p>Formula:C4C5H7N7O2SColore e forma:NeatPeso molecolare:281.239-(2-Hydroxyethyl)guanine
CAS:Prodotto controllato<p>Impurity Aciclovir EP Impurity P<br>Applications 9-(2-Hydroxyethyl)guanine (Aciclovir EP Impurity P) is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>Formula:C7H9N5O2Colore e forma:BeigePeso molecolare:195.181,2,4-Triazole-3-carboxylic Acid
CAS:<p>Impurity Ribavirin EP Impurity C<br>Applications 1,2,4-Triazole-3-carboxylic Acid (Ribavirin EP Impurity C) is a major metabolite of the antiviral agent Ribavirin (R414475).<br>References Miller, J.P. et al.: Ann. N.Y. Acad. Sci., 284, 211 (1977); Catlin, D. et al.: Ribavirin: Broad Spec. Antivir. Ag., 83 (1980); Lin, C.C. et al.: Antimicrob. Ag. Chemother., 50, 2368 (2006);<br></p>Formula:C3H3N3O2Colore e forma:White SolidPeso molecolare:113.07Canagliflozin Furanose Form (Mixture of Anomers)
CAS:Prodotto controllatoFormula:C24H25FO5SColore e forma:NeatPeso molecolare:444.52Emtricitabine (1 mg/mL in Methanol)
CAS:Formula:C8H10FN3O3SColore e forma:ColourlessPeso molecolare:247.25N-(9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
CAS:Prodotto controllatoFormula:C11H15N5O5Colore e forma:NeatPeso molecolare:297.2673(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Triethylammonium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate.<br>References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010);<br></p>Formula:C28H61FN5O14P3Colore e forma:Off White SolidPeso molecolare:803.73
