Nucleosidi e Nucleotidi
I nucleosidi sono composti formati da una base azotata legata a uno zucchero (ribosio o desossiribosio). Quando un gruppo fosfato viene aggiunto al nucleoside, si forma un nucleotide. Questi composti sono fondamentali nella biologia cellulare, poiché i nucleotidi sono i mattoni essenziali del DNA e dell’RNA, responsabili dell’archiviazione e della trasmissione delle informazioni genetiche. I nucleosidi trovano applicazione nel trattamento delle malattie virali, agendo come inibitori della replicazione virale. I nucleotidi, oltre al loro ruolo strutturale negli acidi nucleici, sono coinvolti nei processi energetici, come la sintesi dell’ATP.
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Trovati 3429 prodotti di "Nucleosidi e Nucleotidi"
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Valacyclovir Related Compound D
CAS:<p>Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.</p>Formula:C15H24N6O4Purezza:Min. 95%Peso molecolare:352.39 g/mol5'-Epi lamivudine
CAS:<p>Lamivudine epimer</p>Formula:C8H11N3O3SPurezza:Min. 95%Peso molecolare:229.26 g/mol2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
<p>2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.</p>Formula:C9H12F2N2O6Purezza:Min. 95%Peso molecolare:282.2 g/molAcyclovir EP Impurity Q
<p>Acyclovir EP Impurity Q is a drug product that is used as the impurity standard for Acyclovir EP. It is a natural metabolite of acyclovir and may be found in the urine of patients taking this drug. Acyclovir EP Impurity Q has shown to have antiviral activity against herpes simplex virus type 1 and type 2. The structure of this compound has been determined by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.</p>Purezza:Min. 95%a-Ribavirin (impurity B)
CAS:Prodotto controllato<p>Ribavirin is an antiviral drug that inhibits the synthesis of RNA and DNA. It is used to treat human immunodeficiency virus (HIV) infection, hepatitis B, and influenza A. Ribavirin is a nucleoside analog that acts as an antimetabolite by inhibiting acid synthesis in the host cell and therefore blocking viral replication. Ribavirin has been shown to inhibit dna viruses like herpes simplex virus type 1 and 2, as well as RNA viruses like influenza A and respiratory syncytial virus. Ribavirin also binds to the ribonucleotide reductase enzyme, which is necessary for the production of deoxyribonucleotides from ribonucleotides during DNA synthesis, thereby interfering with DNA replication.</p>Formula:C8H12N4O5Purezza:Min. 95%Peso molecolare:244.2 g/mol2-Deoxy-5-O-toluoyl-D-ribofuranose
CAS:<p>2-Deoxy-5-O-toluoyl-D-ribofuranose is an analytical standard for the determination of purity in drug products. It is also used as a reference compound for HPLC and as a metabolite to study metabolism. This impurity can be synthesized from D-ribose and 2(3,4,5)-O-benzylidenebutyraldehyde.</p>Formula:C13H16O5Purezza:Min. 95%Peso molecolare:252.26 g/molEmpagliflozin tetraacetate
CAS:<p>Empagliflozin tetraacetate is a drug product that has been manufactured by chemical synthesis. It is a white to off-white crystalline powder with a molecular weight of 597.7 and a purity of 98.2%. Empagliflozin tetraacetate has been formulated as the hydrochloride salt, which is soluble in water and alcohols. The USP/BP/EP specifications for this drug are 5% impurity standard, analytical, API impurity, Synthetic, Metabolism studies, niche, High purity>. This drug product can be used in research and development as well as for manufacturing pharmaceutical products. It is not intended for use in humans or animals.</p>Formula:C27H29ClO10Purezza:Min. 95%Peso molecolare:548.97 g/molSofosbuvir impurity 2
CAS:<p>Sofosbuvir impurity 2 is a synthetic compound that is used as an impurity standard for the HPLC assay of sofosbuvir. It is a white to off-white crystalline solid at room temperature.</p>Formula:C22H29ClN3O9PPurezza:Min. 95%Peso molecolare:545.91 g/molRemdesivir impurity 4
CAS:<p>Remdesivir is an antiviral drug that inhibits the viral enzyme, RNA-dependent RNA polymerase. Remdesivir is administered in combination with other antiviral drugs to treat HIV-1 infection. The analytical impurity 4 is a metabolite of remdesivir and has been identified as a potential impurity in the drug product. CAS No. 2096985-18-9 is the molecular weight of this impurity. This impurity can be found in the pharmacopoeia, custom synthesis, natural, or synthetic form.</p>Formula:C21H27N2O7PPurezza:Min. 95%Peso molecolare:450.42 g/molSofosbuvir impurity 3
CAS:<p>Sofosbuvir impurity 3 is a research and development, impurity standard, custom synthesis, drug product, synthetic, high purity, pharmacopoeia, drug development and analytical. Sofosbuvir impurity 3 is a metabolite of sofosbuvir which has been studied in metabolism studies using HPLC. This compound has also been shown to inhibit the growth of some bacteria.</p>Formula:C22H29FN3O9PPurezza:Min. 95%Peso molecolare:529.45 g/molAcyclovir EP impurity R
CAS:<p>Acyclovir EP impurity R is a by-product of acyclovir, which has been shown to be stable in acidic and alkaline conditions. It is also linear with high reproducibility and low detection limits. Acyclovir EP impurity R can be detected using a validated RP-HPLC method with an acidified mobile phase. The compound is not photolyzed under the conditions of the assay. This impurity has been detected in batches of acyclovir that have been produced on two different production lines for more than 5 years without any changes in quality or yield.</p>Formula:C13H21CIN6O4Purezza:Min. 95%Peso molecolare:464.26 g/molRemsesivir related compound 11
CAS:<p>Remsesivir related compound 11 is a research and development chemical that is used as an analytical, drug development, or impurity standard. It is a high purity, pure substance that can be custom synthesized or natural. Remsesivir related compound 11 has been shown to be metabolized by cytochrome p450 enzymes and glutathione reductase and has shown pharmacopoeia activities. Remsesivir related compound 11 can also be used as a HPLC standard for the detection of metabolites in pharmaceutical products.</p>Formula:C15H23Cln04pPurezza:Min. 95%Peso molecolare:347.78 g/molRemdesivir related compound 7
CAS:<p>Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.</p>Formula:C15H17N5O4Purezza:Min. 95%Peso molecolare:331.33 g/molLamivudine acid
CAS:<p>Lamivudine acid is a synthetic orotate prodrug that is converted to the active form, lamivudine. It inhibits the synthesis of viral DNA by inhibiting the reverse transcriptase enzyme and has been used as a treatment for HIV infection. Lamivudine acid is soluble in organic solvents such as acetone and cyclohexane. The crystal structure of this compound has been determined using X-ray crystallography and exhibits a zwitterion structure with a hydrogen bond between the carboxylate group and the amide nitrogen atom of the molecule.</p>Formula:C8H9N3O4SPurezza:Min. 95%Peso molecolare:243.24 g/mol1'-Epi gemcitabine, hydrochloride
CAS:<p>Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.</p>Formula:C9H12ClF2N3O4Purezza:Min. 95%Peso molecolare:299.66 g/molcis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:<p>cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is a drug product that has been custom synthesized for use as an analytical reference material and an impurity standard. It is a synthetic compound and has not been approved for any medicinal purposes. The pharmacopoeia it falls under is the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is used to determine the purity of active pharmaceutical ingredients in finished drug products. It can also be used as a research and development tool to study metabolism studies of natural compounds.</p>Formula:C8H9FN2O4SPurezza:Min. 95%Peso molecolare:248.23 g/molRemdesivir impurity 11
CAS:<p>CAS No. 2096985-18-9 is an impurity of remdesivir, a drug product that is being developed for the treatment of HIV. The purity of this compound is high and it has been shown to be a metabolite in animal studies. Remdesivir impurity 11 has also been shown to have the same pharmacological activities as remdesivir. This compound may be used as an analytical standard or as a research and development tool.</p>Formula:C21H23N6O8PPurezza:Min. 95%Peso molecolare:518.42 g/mol2',3'-Isopropylidene ribavirin
CAS:<p>Intermediate in the synthesis of ribavirin</p>Formula:C11H16N4O5Purezza:Min. 95%Peso molecolare:284.27 g/molSofosbuvir impurity 6
CAS:<p>Sofosbuvir impurity 6 is an impurity in the drug Sofosbuvir. It is a metabolite that is a by-product of the synthesis process of Sofosbuvir, which is used to treat chronic hepatitis C infection. The purity of this compound has been tested with HPLC and found to be 99.99% pure. This compound can also be synthesized from natural or synthetic sources.</p>Formula:C31H27N3O7Purezza:Min. 95%Peso molecolare:553.56 g/molRemdesivir impurity 3 HCl
CAS:<p>Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0</p>Formula:C9H19NO2·HClPurezza:Min. 95%Peso molecolare:209.71 g/mol
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