APIs per la ricerca e le impurità
Sottocategorie di "APIs per la ricerca e le impurità"
- Aminoacidi e Derivati(12.335 prodotti)
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- Derivati delle Benzodiazepine(334 prodotti)
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- Antibiotici Naturali e Semisintetici(6.387 prodotti)
- Nitrili e Derivati Ciano(3.068 prodotti)
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- Composti β-Adrenergic(231 prodotti)
Trovati 57768 prodotti di "APIs per la ricerca e le impurità"
5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane
CAS:5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane is an analytical standard used in HPLC and GC. It can also be used as a research and development standard or impurity to aid in the identification of compounds with similar structures. 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane has a purity of 99% and a melting point of 80°C. The CAS number for this compound is 93413-70-8, and it is available for custom synthesis, natural, or synthetic production.
Formula:C17H25NO2Purezza:Min. 95%Peso molecolare:275.39 g/molRef: 3D-IM28679
Prodotto fuori produzioneBenzathine ampicillin
CAS:Benzathine ampicillin is a penicillin antibiotic that belongs to the group of β-lactam antibiotics. It is used as an analytical reference standard in the pharmaceutical industry, and is also used as a high purity API impurity. Benzathine ampicillin has been shown to be metabolized by liver enzymes into penicillin G and 6-aminopenicillanic acid. The pharmacopoeia requires that benzathine ampicillin be at least 98% pure for its use in drug products.
Formula:C48H58N8O8S2Purezza:Min. 95%Peso molecolare:939.20 g/molDeschloro-zopiclone
CAS:Deschloro-zopiclone is a drug product that is custom synthesized for research and development purposes. It is a synthetic drug that has been shown to have pharmacological properties in the treatment of insomnia. Deschloro-zopiclone is metabolized by hydrolysis, oxidation and conjugation, with the major metabolites being 2,5-dimethoxybenzoic acid and 2-hydroxy-5-methoxybenzoic acid. The metabolite 2,5-dimethoxybenzoic acid has been shown to be responsible for the hypnotic effects of deschloro-zopiclone.
Formula:C17H18N6O3Purezza:Min. 95%Peso molecolare:354.4 g/molRef: 3D-YDC04661
Prodotto fuori produzioneN-Methyl metribuzin
CAS:N-Methyl metribuzin is a drug product that belongs to the class of organic compounds known as phenylureas. It is a natural substance, which can be found in plants such as dandelion and rhubarb. Metribuzin has been shown to have pharmacological effects on the human body, including antimetabolite activity, anticancer activity, and anti-inflammatory activities. Metribuzin is metabolized by cytochrome P450 enzymes to form metabolites that are excreted in urine or bile. The metabolites are also active substances and may contribute to the pharmacological effects of metribuzin. Metribuzin can be synthesized from 2-chloro-5-(trifluoromethyl)benzoyl chloride and 3-methylisoxazole.
Metribuzin is used as an analytical standard for HPLC analysis because it has a high purity level and analytical quality. It is also used inFormula:C9H16N4OSPurezza:Min. 95%Colore e forma:PowderPeso molecolare:228.32 g/molMesulergine hydrochloride
CAS:Mesulergine hydrochloride is a drug that inhibits the dopamine and serotonin receptors. It has been shown to have an effect on rats' serum prolactin levels, food composition, and protein transport in the striatum. Mesulergine hydrochloride can also decrease 5-HT7 receptor binding and increase dopamine release from nerve terminals in the rat brain. This drug has synergistic effects with other drugs when used in combination, such as gamma-aminobutyric acid (GABA) or benzodiazepines.
Symptoms of mesulergine hydrochloride include psychotic disorders, anxiety, depression, hallucinations, sleep problems, and suicidal thoughts. These symptoms may be due to mesulergine's effect on 5-HT2C receptors.Formula:C18H27ClN4O2SPurezza:Min. 95%Peso molecolare:399 g/mol4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-pyridinium Chloride Monoh ydrochloride
CAS:4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium Chloride Monohydrochloride is a drug product under development for the treatment of bacterial infections. 4-[2-[(6R,7R)-7Amino--2carboxy8oxo5thia1azabicyclo[4.2.0]oct2en3yl]thio]-4thiazolyl]-1methylpyridinium Chloride Monohydrochloride is an impurity in the API Methicillin (CAS No. 40082764). Impurities are not necessarily undesirable and may have substantial therapeutic value or provide a desired
Formula:C16H15N4O3S3·Cl·HClPurezza:Min. 95%Peso molecolare:479.43 g/molTetracosanoic-d47 acid
CAS:Prodotto controllatoTetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.
Formula:C24HD47O2Purezza:Min. 95%Peso molecolare:415.93 g/mol2-Methoxy-5-sulfamoylbenzoic acid
CAS:2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.
2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antifFormula:C8H9NO5SPurezza:Min. 95%Peso molecolare:231.23 g/molRef: 3D-IM145487
Prodotto fuori produzione2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid
CAS:2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.Formula:C19H29O6PPurezza:Min. 95%Peso molecolare:384.4 g/molRef: 3D-IM27637
Prodotto fuori produzioneo-Acetyl silodosin
CAS:O-Acetyl silodosin is a synthetic, natural metabolite of silodosin. It is a nicotinic acid derivate that inhibits the activity of phosphodiesterase type 5 (PDE5) and has been used as a research and development standard for PDE5 inhibitors. O-Acetyl silodosin is an impurity in the commercial drug product, Silodosin®.
Formula:C27H34F3N3O5Purezza:Min. 95%Peso molecolare:537.60 g/molTrazodone Impurity A
CAS:Trazodone Impurity A is a drug product that is an impurity standard for Trazodone. It has been classified as a synthetic metabolite and is used in analytical research studies. Trazodone Impurity A has demonstrated niche applications in the pharmaceutical industry, including metabolism studies, pharmacopoeia requirements, and HPLC standards.
Formula:C19H22ClN5OPurezza:Min. 95%Peso molecolare:371.86 g/molBenzylidene camphor sulfonic acid
CAS:Benzylidene camphor sulfonic acid is a non-volatile, oil-soluble, water-insoluble, white solid. It can be formulated as a microcapsule to provide sun protection and to protect against the effects of radiation. Benzylidene camphor sulfonic acid is used in pharmaceutical preparations for the treatment of psoriasis and other skin conditions. It has been shown to have sunscreen activity due to its ability to absorb ultraviolet light. The sunscreen property of benzylidene camphor sulfonic acid may be due to its ability to absorb ultraviolet light and release it in the form of heat or infrared radiation. Benzylidene camphor sulfonic acid also has an antibacterial effect on some strains of bacteria such as Sarcina lutea and Bacillus subtilis.
Formula:C17H20O4SPurezza:Min. 95%Peso molecolare:320.4 g/molChloromethyl olanzapinium chloride
CAS:Chloromethyl olanzapinium chloride is an analytical reference material that can be used as a standard for HPLC-UV analysis. It is also used in the development of new drugs and as an impurity standard during drug manufacturing. Chloromethyl olanzapinium chloride has been shown to be a metabolite of Olanzapine, which is a niche drug product that is not commercially available. Chloromethyl olanzapinium chloride is listed by the USP, EP and JP as a drug product impurity. It can be synthesized from natural or synthetic sources.
Formula:C18H22Cl2N4SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:397.37 g/molN-Acetyl N-descarboxyethyl retigabine d4
CAS:N-Acetyl N-descarboxyethyl retigabine (D4) is a pharmaceutical drug that is used for the treatment of epilepsy. It has been shown to be effective in patients who have not responded to other treatments. D4 binds to voltage-gated potassium channels and inhibits their opening, which leads to a decrease in neurotransmitter release from nerve cells. The mechanism by which D4 induces epileptic seizures is unclear but may be due to its ability to inhibit the activity of GABA receptors in the brain.Formula:C15H16FN3OPurezza:Min. 95%Peso molecolare:273.3 g/molDioctyl carbonate
CAS:Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.
Formula:C17H34O3Purezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:286.4 g/molMinocycline EP Impurity H
CAS:Please enquire for more information about Minocycline EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C23H25N3O7Purezza:Min. 95%Peso molecolare:455.47 g/molRef: 3D-IM183785
Prodotto fuori produzioneDL-threo-Ritalinic acid
CAS:Prodotto controllatoDL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.
Formula:C13H17NO2Purezza:Min. 95%Peso molecolare:219.28 g/molN-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride
CAS:N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.
Formula:C14H17N5O2·HClPurezza:Min. 95%Peso molecolare:323.78 g/molRef: 3D-IA156915
Prodotto fuori produzioneCelecoxib hydraziney
CAS:Celecoxib hydrazine is an inhibitor of protein kinases that has been shown to have anticancer properties. It is an analog of celecoxib, a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to treat pain and inflammation. Celecoxib hydrazine has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in mice. This compound has potential as a medicinal agent for the treatment of cancer, and urine samples from Chinese patients with cancer have been found to contain high levels of this compound. Celecoxib hydrazine acts on specific kinases in the body, which are involved in various cellular processes such as cell cycle regulation and signal transduction. Its ability to selectively inhibit these kinases makes it a promising candidate for targeted therapy against cancer.
Formula:C8H8F3N3O3SPurezza:Min. 95%Peso molecolare:283.23 g/molRef: 3D-QLB28081
Prodotto fuori produzione3-Oxo-1,2-benzoisothiazoline-2-acetic acid methyl ester 1,1-dioxide
CAS:Meloxicam is a nonsteroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and rheumatoid arthritis. It has been shown to reduce the number of exacerbations in patients with juvenile idiopathic arthritis. Meloxicam also inhibits the production of Cox-2, which is an enzyme that produces inflammation in joints. The oral route of administration allows meloxicam to be distributed through the body. This drug is not active against ankylosing spondylitis and it should not be taken by pregnant women or children under 12 years old.
Formula:C10H9NO5SPurezza:Min. 95%Peso molecolare:255.25 g/mol5-[(Desloratadine)methyl] rupatadine
CAS:Desloratadine is a drug that belongs to the group of antihistamines and is indicated for the treatment of allergic rhinitis. It has been shown to be as effective as loratadine, cetirizine, and fexofenadine in clinical trials. Desloratadine is metabolized by cytochrome P450 enzymes including CYP2D6 to its active form, desloratadine N-oxide. The metabolites are excreted in the urine.
Formula:C45H43Cl2N5Purezza:Min. 95%Peso molecolare:724.80 g/molN’-(4-Acetylaminophenyl)-N,N-dimethylacetamidine
CAS:N’-(4-Acetylaminophenyl)-N,N-dimethylacetamidine is a drug product that is used in the development of new drugs. It has high purity, analytical grade and natural origin. It is an impurity standard used in metabolite identification and research and development. The CAS number for this compound is 1358054-66-6.Formula:C12H17N3OPurezza:Min. 95%Peso molecolare:219.28 g/molAdefovir dipivoxil dimer
CAS:Adefovir dipivoxil dimer is a synthetic and natural product that is used as an analytical standard for HPLC, as well as in the development of new drug products. It is also used to identify impurities in API. Adefovir dipivoxil dimer has CAS number 323201-05-4 and can be found on the FDA Orange Book.
Formula:C41H64N10O16P2Purezza:Min. 95%Peso molecolare:1,014.95 g/molPravastatin diol lactone
CAS:Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.
Formula:C18H26O5Purezza:Min. 95%Peso molecolare:322.4 g/molBupivacaine N-oxide hydrochloride
CAS:Bupivacaine N-oxide is a synthetic local anesthetic drug. It is a metabolite of bupivacaine and has been shown to be active in animal studies. The chemical name for bupivacaine N-oxide is 4-oxo-2,6,8-trimethylquinoline. Bupivacaine N-oxide hydrochloride (N06) is an impurity standard that meets the USP/BP requirements for purity and quality as well as the pharmacopoeia standards for analytical methods. The compound has been synthesized by custom synthesis and research and development from Impurity Standard Bupivacaine Hydrochloride (CAS No. 1796927-05-3). The compound is used in the synthesis of drug products, including analgesics and anaesthetics. The compound can be used in analytical studies due to its high purity and quality standards.
Formula:C18H29ClN2O2Purezza:Min. 95%Peso molecolare:340.9 g/molLy 2389575 hydrochloride
CAS:Ly 2389575 hydrochloride is a drug product for the treatment of rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. It is synthesized in a natural manner from the fermentation of Streptomyces lavendulae. The compound has been shown to be metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ly 2389575 hydrochloride also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
Formula:C15H16BrCl3N4Purezza:Min. 95%Peso molecolare:438.6 g/molRef: 3D-KKB10409
Prodotto fuori produzione2-Phenylbutyramide
CAS:2-Phenylbutyramide is a drug that acts as a potent, nonselective agonist at adenosine A3 receptors. It has been shown to have therapeutic potential for the treatment of bowel disease and cardiac diseases. 2-Phenylbutyramide binds to the adenosine A3 receptor and triggers an increase in intracellular calcium levels, which leads to smooth muscle relaxation in the gut. This drug also has been found to be effective against autoimmune diseases and organometallic toxicity. It is not active against bacterial infections such as hepatitis or inflammatory bowel disease.
Formula:C10H13NOPurezza:Min. 95%Peso molecolare:163.22 g/molRef: 3D-IP145636
Prodotto fuori produzioneN-(2-Hydroxyethyl)-P,P-bisaziridinyl thiophosphamide
CAS:N-(2-Hydroxyethyl)-P,P-bisaziridinyl thiophosphamide (HEPBTP) is a metabolite of the drug product. HEPBTP is synthesized from the parent compound by hydrolysis and oxidation reactions. This metabolite has been characterized using HPLC and analytical methods, including mass spectrometry. It is also included in the pharmacopoeia as an impurity standard for quality control.
Formula:C6H15N3O4PSPurezza:Min. 95%Peso molecolare:256.24 g/molRef: 3D-IH180621
Prodotto fuori produzione9-Epimitomycin B
CAS:9-Epimitomycin B is a water-soluble, alkoxy-substituted amino compound that is used medicinally. It has antibacterial activity and has been shown to be effective against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. 9-Epimitomycin B inhibits the growth of these bacteria by binding to their ribosomes and inhibiting protein synthesis. The carbon atoms in 9-epimitomycin B are linked to an alkoxy group at one end, which causes it to have a higher affinity for bacterial ribosomes than human ribosomes. 9-Epimitomycin B also binds to mitomycin C, which may be responsible for its antimetabolite properties.
Formula:C16H19N3O6Purezza:Min. 95%Peso molecolare:349.34 g/molRef: 3D-NAA16490
Prodotto fuori produzioneSpirolaxine
CAS:Spirolaxine is a coumarin derivative that has been shown to have anti-cancer properties. It was isolated from an extract of the fungus Spirolaxine, which was found in the gastroduodenum (gut) of a frog. The structure of spirolaxine is similar to that of retinoic acid, and it has been shown to inhibit cancer cell proliferation. Spirolaxine also inhibits the production of proinflammatory cytokines in mice with colitis. This drug has not yet been tested for its ability to treat other diseases, such as diabetes, but may be able to regulate blood sugar levels by inhibiting insulin secretion and increasing glucose uptake by cells.
Formula:C23H32O6Purezza:Min. 95%Peso molecolare:404.5 g/molRef: 3D-BFA38201
Prodotto fuori produzionePropoxyphenyl homohydroxysildenafil
CAS:Propoxyphenyl homohydroxysildenafil is a preparative mass spectrometric analysis of the metabolite of sildenafil, which is a phosphodiesterase type 5 inhibitor. It has been shown to increase the flow rate in rats with an experimental pulmonary hypertension. The product ions of propoxyphenyl homohydroxysildenafil are m/z 409.3, 417.2, and 419.2, and its pharmacological study has been conducted on tadalafil and isobutyl.Formula:C24H34N6O5SPurezza:Min. 95%Peso molecolare:518.6 g/mol4-Amino-5,6-dimethoxypyrimidine
CAS:4-Amino-5,6-dimethoxypyrimidine is a pyrimethamine derivative that has been used as an antimalarial agent. It is a high yield compound with a chromatographic profile that can be used to identify impurities of other compounds. 4-Amino-5,6-dimethoxypyrimidine is eluted at the same time as sulfadoxine and can be used to calculate the concentration of sulfadoxine in a mixture. It can also be used as a reagent for rp-hplc. The linearity of this compound was tested by calibrating it against pyrimethamine and quantifying it using UV/Vis spectroscopy over the range 0.05 to 1 mg/mL.
Formula:C6H9N3O2Purezza:Min. 95%Peso molecolare:155.15 g/molRef: 3D-IA34066
Prodotto fuori produzioneAlfuzosin hydrochloride EP Impurity F hydrochloride
CAS:Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.
Formula:C12H16N4O2•HClPurezza:Min. 95%Peso molecolare:284.74 g/mol(E,Z)-Epalrestat methyl ester
CAS:(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.
Formula:C16H15NO3S2Purezza:Min. 95%Peso molecolare:333.43 g/molRef: 3D-HCB77570
Prodotto fuori produzioneMonobenzyl fosaprepitant
CAS:Monobenzyl fosaprepitant is a drug product that is used for research and development purposes. It is an impurity standard for the analysis of API (Active Pharmaceutical Ingredient) impurities, which are synthetic products. Monobenzyl fosaprepitant has been shown to be metabolized in vitro. The metabolism studies have shown that this compound can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid. Monobenzyl fosaprepitant is a high-purity analytical standard and is used as a pharmacopoeia monograph material.
Formula:C30H28F7N4O6PPurezza:Min. 95%Peso molecolare:704.50 g/molRef: 3D-PKB85202
Prodotto fuori produzionecis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Formula:C22H19N3O4Purezza:Min. 95%Colore e forma:White/Off-White SolidPeso molecolare:389.4 g/molAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Purezza:Min. 95%Ref: 3D-FA175652
Prodotto fuori produzioneN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Formula:C10H15N3O5S3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:353.44 g/mol(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Formula:C16H20N6OPurezza:Min. 95%Peso molecolare:312.37 g/mol3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Formula:C19H25ClN2O2Purezza:Min. 95%Peso molecolare:348.9 g/molRef: 3D-WMD18565
Prodotto fuori produzioneCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Formula:C15H16FN3O3Purezza:Min. 95%Peso molecolare:305.30 g/molN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Formula:C15H23N3O3SPurezza:Min. 95%Peso molecolare:325.43 g/molLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Formula:C25H28N8O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:472.54 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Formula:C24H27NO4Purezza:Min. 95%Peso molecolare:393.48 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Formula:C23H29N5O8SPurezza:(Elemental Analysis) Min. 90 Area-%Colore e forma:PowderPeso molecolare:535.57 g/molN-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Formula:C20H27NO3Purezza:Min. 95%Peso molecolare:329.4 g/molTerbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Formula:C36H40N2Purezza:Min. 95%Peso molecolare:500.7 g/molOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C44H71NO13Purezza:Min. 95%Peso molecolare:822.04 g/molRef: 3D-IO183660
Prodotto fuori produzioneRocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Formula:C34H55N2O4·BrPurezza:Min. 95%Peso molecolare:635.72 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Formula:C12H9BrN2OPurezza:Min. 95%Peso molecolare:277.12 g/molEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Formula:C23H27ClO7Purezza:Min. 95%Colore e forma:PowderPeso molecolare:450.91 g/molIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Formula:C48H74O14Purezza:Min. 95%Colore e forma:PowderPeso molecolare:875.09 g/mol(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C19H15ClOPurezza:Min. 95%Peso molecolare:294.8 g/molRef: 3D-GAA92289
Prodotto fuori produzioneTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Formula:C16H22N6OPurezza:Min. 95%Peso molecolare:314.39 g/molRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Formula:C16H14Cl2N2O3Purezza:Min. 95%Peso molecolare:353.2 g/molSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Formula:C25H40O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:436.58 g/molDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Formula:C6H11N•HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:133.62 g/molN-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Formula:C25H31NO9SPurezza:Min. 95%Peso molecolare:521.58 g/molDesfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formula:C24H22FNO3Purezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:391.43 g/mol(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Formula:C18H21N3O3S•NaPurezza:Min. 95%Peso molecolare:382.43 g/molRef: 3D-IR183125
Prodotto fuori produzionePramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Formula:C20H32N6S2Purezza:Min. 95%D-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C17H15N3O2Purezza:Min. 95%Peso molecolare:293.32 g/molChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Formula:C14H11ClN2O3SPurezza:Min. 95%Peso molecolare:322.77 g/molRef: 3D-IC76330
Prodotto fuori produzioneTriethylene glycol flufenamate
CAS:Etofenamate impurity
Formula:C20H22F3NO5Purezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:413.39 g/molGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Formula:C12H12N5O13P3·4NaPurezza:(31P-Nmr) Min. 95 Area-%Colore e forma:White PowderPeso molecolare:531.20 g/molRef: 3D-FG167050
Prodotto fuori produzioneAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Formula:C34H37FN2O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:572.67 g/mol
