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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • 1-Methoxy-5-(methoxymethoxy)-naphthalene

    CAS:

    Please enquire for more information about 1-Methoxy-5-(methoxymethoxy)-naphthalene including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C13H14O3
    Purezza:Min. 95%
    Peso molecolare:218.25 g/mol

    Ref: 3D-DDA17648

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  • N-Methyl formoterol fumarate

    CAS:

    N-Methyl formoterol fumarate is a drug product for the treatment of asthma and chronic obstructive pulmonary disease. It is a synthetic drug that has been approved by the FDA, but is also a metabolite of terbutaline. Metabolism studies have shown that N-methyl formoterol fumarate is an impurity in Terbutaline sulfate and Terbutaline hydrochloride. This drug is not active against bacteria, but may be used as an analytical standard to measure the purity of other drugs.

    Formula:C44H56N4O12
    Purezza:Min. 95%
    Peso molecolare:832.94 g/mol

    Ref: 3D-VWC13397

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  • rac-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine

    CAS:
    Rac-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine is an organic compound with the molecular formula C10H14N. Racemic rac-1,2,3,4-tetrahydro-5-methoxy-N propyl 2 naphthalenamine has been used in the synthesis of rotigotine. The enantiomers can be separated by means of an electrophoretic method. Racemic rac 1,2 3 4 tetrahydro 5 methoxy n propyl 2 naphthalenamine has a melting point range of 138 to 141 °C and a boiling point range of 285 to 288 °C at atmospheric pressure. This compound is soluble in organic solvents such as chloroform and ethanol and insoluble in water. It has a density of 1.07 g/cm3 at 20 °C and it is
    Formula:C14H21NO
    Purezza:Min. 95%
    Peso molecolare:219.32 g/mol

    Ref: 3D-DAA89907

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  • Ethyl 2-methoxy-5-sulfamoylbenzoate

    CAS:

    Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.

    Formula:C10H13NO5S
    Purezza:Min. 95%
    Peso molecolare:259.28 g/mol

    Ref: 3D-IE140268

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  • Anhydro galanthamine

    Prodotto controllato
    CAS:

    Anhydro galanthamine is a drug product that is custom synthesized to meet the needs of researchers. The purity of this compound can range from 99% to 99.99%. This molecule has been extensively studied and is found to be metabolized by CYP1A2, CYP3A4, and CYP2D6. Anhydro galanthamine also inhibits the synthesis of acetylcholine in the brain, which may lead to its use as a treatment for Alzheimer's disease.

    Formula:C17H19NO2
    Purezza:Min. 95%
    Peso molecolare:269.34 g/mol

    Ref: 3D-PBB99565

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  • Trazodone Hydrochloride BP Impurity A

    CAS:
    Trazodone Hydrochloride BP Impurity A is an unproven impurity of Trazodone. It inhibits the uptake of serotonin by 5-HT receptors, which may be important in the treatment of depression. This compound also inhibits platelet aggregation and has been found to inhibit the activity of tricyclic compounds, such as piperazine and propionic acid.
    Formula:C19H22CIN5O2
    Purezza:Min. 95%
    Peso molecolare:491.33 g/mol

    Ref: 3D-IT171024

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  • DL-threo-Ritalinic acid

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    CAS:

    DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.

    Formula:C13H17NO2
    Purezza:Min. 95%
    Peso molecolare:219.28 g/mol

    Ref: 3D-IR180350

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  • Dihydrexidine hydrochloride

    CAS:

    Dihydrexidine hydrochloride is a phosphate ion transport inhibitor that binds to the acetylcholine transporter, and inhibits the uptake of acetylcholine in the brain. It is used as an opioid analgesic, as well as to treat depression, cognitive disorders, and Parkinson's disease. Dihydrexidine hydrochloride binds to the catechol-O-methyltransferase (COMT) enzyme and prevents it from breaking down dopamine. This leads to increased levels of dopamine in the synapse and enhanced transmission of nerve impulses between neurons. Dihydrexidine hydrochloride also has been shown to bind to antigen molecules on cells, which may be important for its antiviral properties.

    Formula:C17H18ClNO2
    Purezza:Min. 95%
    Peso molecolare:303.8 g/mol

    Ref: 3D-IGA70402

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  • Albendazole impurity F

    CAS:

    Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.

    Formula:C10H11N3O2S
    Purezza:Min. 95%
    Peso molecolare:237.28 g/mol

    Ref: 3D-IA71873

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  • (E,Z)-Epalrestat methyl ester

    CAS:

    (E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.

    Formula:C16H15NO3S2
    Purezza:Min. 95%
    Peso molecolare:333.43 g/mol

    Ref: 3D-HCB77570

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  • 1-Glycoloyl-L-prolinamide

    CAS:

    1-Glycoloyl-L-prolinamide is a drug product that is an analytical standard for the impurity 1-glycoloyl-L-proline (CAS No. 96166-39-1) in the API 1,4,5,6-tetrahydrobenzothiazole (CAS No. 86687-93-0). It has been synthesized to be used as an impurity standard and is provided at a purity of 98.0% or greater by weight. This chemical compound can be used in research and development for the production of drugs as well as in pharmaceutical manufacturing.

    Formula:C7H12N2O3
    Purezza:Min. 95%
    Peso molecolare:172.18 g/mol

    Ref: 3D-FG167741

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  • Salbutamol Impurity D

    CAS:

    Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.

    Formula:C13H19NO3
    Purezza:Min. 95%
    Peso molecolare:237.29 g/mol

    Ref: 3D-FS170974

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  • rac 5-Keto Fluvastatin

    CAS:

    Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.

    Formula:C24H24FNO4
    Purezza:Min. 95%
    Colore e forma:Yellow Powder
    Peso molecolare:409.45 g/mol

    Ref: 3D-IK162498

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  • [5-L-Aspartic Acid]-desmopressin


    Desmopressin is a synthetic drug that is used to treat diabetes insipidus and bleeding in patients who are on anticoagulants. It is also used as a diagnostic agent to distinguish between central and nephrogenic diabetes insipidus. Desmopressin is a peptide hormone with amino acid sequence L-Asp-D-Phe-L-Arg-L-Phe. It is synthesized by the combination of two amino acids, L-Aspartic Acid and L-Phenylalanine, which are then linked together through an amide bond. The synthesis of desmopressin occurs in two steps: first, the coupling of amino acid L-Aspartic Acid with the peptide linkage (N-[3-(2'-aminoethyl) carbonyl]glycine) to form the intermediate N-[3-(2'-Aminoethyl) carbonyl]-L-Aspartic Acid; second

    Purezza:Min. 95%

    Ref: 3D-IA173260

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  • Dioctyl carbonate

    CAS:

    Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.

    Formula:C17H34O3
    Purezza:Min. 95%
    Colore e forma:Clear Liquid
    Peso molecolare:286.4 g/mol

    Ref: 3D-BAA68031

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  • Esomeprazole Impurity Q


    Esomeprazole Impurity Q is a drug product. It is an impurity standard of esomeprazole, CAS No. 131428-60-1, which is used in the development of drugs and as an analytical reagent. It is synthesized from natural materials and has a purity of 99%. The metabolite can be found in animal and human metabolism studies. Esomeprazole Impurity Q is used for niche purposes such as HPLC standards, analytical reagents, or pharmacopoeia reference substances.

    Purezza:Min. 95%

    Ref: 3D-IE177226

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  • 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan

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    CAS:
    4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-
    Formula:C22H22N2O6
    Purezza:Min. 95%
    Peso molecolare:410.4 g/mol

    Ref: 3D-JGA30803

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  • Rotigotine Impurity 18

    Prodotto controllato
    CAS:

    Rotigotine Impurity 18 is a drug product that is an analytical standard for impurities. It is a synthetic impurity that is not found in natural sources. Rotigotine Impurity 18 has been used as a pharmacopoeia reference in the development of rotigotine, which is used to treat Parkinson's disease. This synthetic impurity has been extensively studied for its metabolism and toxicity properties.

    Formula:C21H27NO2S
    Purezza:Min. 95%
    Peso molecolare:357.5 g/mol

    Ref: 3D-IR181651

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  • Ajoene

    CAS:

    Ajoene is a natural compound that has been shown to have antimicrobial properties, as well as an ability to inhibit the growth of tumor cells. Ajoene is also a potent inhibitor of dextran sulfate proteoglycan synthesis in vitro and has been shown to produce a hypoglycemic effect in vivo. Ajoene has been shown to be active against Gram-positive bacteria and fungi and may have potential applications for the treatment of infectious diseases. Further research is needed to determine whether ajoene may be used as an antioxidant or neuroprotective agent.

    Formula:C9H14OS3
    Purezza:Min. 95%
    Peso molecolare:234.4 g/mol

    Ref: 3D-SDA28499

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  • 5-Desbromo, 5-chloro brimonidine

    CAS:

    5-Desbromo, 5-chloro brimonidine is a drug product that is used as an analytical standard. It has been shown to be metabolized by CYP3A4 and CYP2D6 enzymes.

    Formula:C11H10ClN5
    Purezza:Min. 95%
    Peso molecolare:247.68 g/mol

    Ref: 3D-RDA14746

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  • 5-[(Desloratadine)methyl] rupatadine

    CAS:

    Desloratadine is a drug that belongs to the group of antihistamines and is indicated for the treatment of allergic rhinitis. It has been shown to be as effective as loratadine, cetirizine, and fexofenadine in clinical trials. Desloratadine is metabolized by cytochrome P450 enzymes including CYP2D6 to its active form, desloratadine N-oxide. The metabolites are excreted in the urine.

    Formula:C45H43Cl2N5
    Purezza:Min. 95%
    Peso molecolare:724.80 g/mol

    Ref: 3D-ZYB51572

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  • (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt

    CAS:

    (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt is a synthetic drug product. It is an impurity standard in the synthesis of Metabolism studies. The CAS number is 1714147-50-8 and the chemical name is (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2 methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5dihydroxyheptenoic acid sodium salt. The molecular weight is 781

    Formula:C25H33FN3NaO7S
    Purezza:Min. 95%
    Peso molecolare:561.6 g/mol

    Ref: 3D-IF156830

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  • Retinyl retinoate

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    CAS:

    Retinyl retinoate is a synthetic retinoid that is chemically stable and has been shown to be effective in clinical studies. Retinyl retinoate is a lipophilic molecule with antioxidant properties, and it also has the ability to bind to hyaluronic acid and other natural compounds to maintain skin condition. This compound is synthesized by esterification of all-trans-retinoic acid with fatty acids, such as oleic acid or linoleic acid. The chemical structure of this compound can be determined by nuclear magnetic resonance spectroscopy.

    Formula:C40H56O2
    Purezza:Min. 95%
    Peso molecolare:568.9 g/mol

    Ref: 3D-QAA49886

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  • N-Isopropylnoradrenochrome

    CAS:

    N-Isopropylnoradrenochrome is used as a fluorescent substrate for hydroxylamine. It has also been shown to be a useful catalyst for the synthesis of alkali metal hydrazides and to have hypotensive properties. N-Isopropylnoradrenochrome has been used in the synthesis of pharmaceutical preparations, such as migraine prophylaxis, and yields an hydrazone when irradiated with light.

    Formula:C11H13NO3
    Purezza:Min. 95%
    Peso molecolare:207.23 g/mol

    Ref: 3D-DAA73631

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  • Aminopentamide sulfate

    CAS:

    Aminopentamide sulfate is a pharmaceutical dosage form that is a polymeric matrix containing glycol ether, fatty acid ester, and glycol ester. It is used as a local anesthetic to numb the skin and other tissues. Aminopentamide sulfate can be administered topically or by injection into the body. It has been shown to have therapeutic effects on animals with pain-related conditions such as arthritis and neuropathy. The intramolecular hydrogen bonds in aminopentamide sulfate are thought to be formed between the carbonyl group of atropine sulfate and the hydroxyl groups of benzimidazole derivatives. These functional groups form hydrogen bonds with fatty alcohols in the matrix, which may help stabilize it.

    Formula:C19H26N2O5S
    Purezza:Min. 95%
    Peso molecolare:394.5 g/mol

    Ref: 3D-VAA70177

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  • (6R)-Folinic acid

    CAS:

    (6R)-Folinic acid is an impurity standard and a metabolite of folic acid. It is synthesized by the body in the liver, where it is converted to 5,10-methylenetetrahydrofolate (5,10-MTHF). This metabolite is used to convert homocysteine into methionine, which can then be converted into S-adenosylmethionine (SAMe), a compound that has been shown to have antidepressant properties. The methylation of folate also helps to regulate DNA synthesis and repair. (6R)-Folinic acid has been used in research as a drug development tool for studying folate metabolism and its effects on the central nervous system. High purity standards are available for use in HPLC analysis of this compound.

    Formula:C20H23N7O7
    Purezza:Min. 95%
    Peso molecolare:473.40 g/mol

    Ref: 3D-YCA95154

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  • Ciprofibrate methyl ester

    CAS:

    Ciprofibrate methyl ester is an analytical standard that can be used for the detection of impurities in drug products. It is a metabolite of Ciprofibrate and is used as a reference material for HPLC. The impurity standards are available in high purity or with different levels of purity, depending on the application. In addition, it can be custom synthesized to meet specific needs. This product has been tested according to the requirements of the USP-NF and has been found to meet these requirements.

    Formula:C14H16Cl2O3
    Purezza:Min. 95%
    Peso molecolare:303.2 g/mol

    Ref: 3D-FFA23251

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  • (2S,4R)-Fosinopril sodium salt

    CAS:

    (2S,4R)-Fosinopril sodium salt is a prodrug that is converted to the active form fosinopril in the body. It is used to treat high blood pressure and heart failure. Fosinopril inhibits angiotensin-converting enzyme (ACE) and blocks the conversion of angiotensin I to angiotensin II. This leads to an increase in the production of a vasodilator called nitric oxide, which relaxes and widens blood vessels. Fosinopril also has been shown to have adverse effects on liver function, including increased liver enzymes and liver damage, as well as drug interactions with other nonsteroidal anti-inflammatory drugs (NSAIDs).

    Formula:C30H45NNaO7P
    Purezza:Min. 95%
    Peso molecolare:585.64 g/mol

    Ref: 3D-GEC35341

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  • Desisobutyl-N-butyl bortezomib

    CAS:

    Desisobutyl-N-butyl bortezomib is a drug product that has been custom synthesized for the purpose of research and development. The synthetic compound is an impurity standard for the API Desisobutyyl-N-butyl bortezomib. This API is metabolized in both humans and rats, with metabolites being found in urine, feces, and exhaled air. The impurities in this drug product are a result of incomplete synthesis and are not of natural origin.

    Formula:C19H25BN4O4
    Purezza:Min. 95%
    Peso molecolare:384.2 g/mol

    Ref: 3D-EUB01135

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  • Terbutaline impurity b

    CAS:

    Terbutaline impurity b is a pharmacopoeia grade drug product that is used as an analytical standard. It is also used in the synthesis of terbutaline, which is a drug that has been approved by the FDA to treat bronchospasm, asthma and other lung disorders. Terbutaline impurity b may be found in natural sources or may be synthesized. This impurity can be custom synthesized using HPLC-grade reagents and can be obtained at high purity levels.

    Purezza:Min. 95%

    Ref: 3D-IT182020

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  • 2-[2-[4-(5,5-Dioxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]ethanol

    CAS:

    Quetiapine is a drug that belongs to the class of sulfoxides. It is usually administered orally, but can also be given intravenously or intramuscularly. Quetiapine has been studied for its clinical use in the treatment of schizophrenia and bipolar disorder. The plasma concentrations of quetiapine are determined by high-performance liquid chromatography (HPLC) with tandem mass spectrometry (LC-MS/MS) detection. Validation studies have shown that the HPLC-MS/MS method is accurate and precise, with good linearity over a range of concentrations. Analysis was performed on plasma samples from healthy volunteers who were administered either 2 mg or 10 mg doses of quetiapine by intravenous injection. Concentrations were calculated and compared to those found in patients with schizophrenia and bipolar disorder who had been given oral doses of 300 mg per day for four weeks, yielding a therapeutic plasma concentration range from 100 to 300 ng/mL.

    Formula:C21H25N3O4S
    Purezza:Min. 95%
    Peso molecolare:415.51 g/mol

    Ref: 3D-ID27366

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  • Benzylidene camphor sulfonic acid

    CAS:

    Benzylidene camphor sulfonic acid is a non-volatile, oil-soluble, water-insoluble, white solid. It can be formulated as a microcapsule to provide sun protection and to protect against the effects of radiation. Benzylidene camphor sulfonic acid is used in pharmaceutical preparations for the treatment of psoriasis and other skin conditions. It has been shown to have sunscreen activity due to its ability to absorb ultraviolet light. The sunscreen property of benzylidene camphor sulfonic acid may be due to its ability to absorb ultraviolet light and release it in the form of heat or infrared radiation. Benzylidene camphor sulfonic acid also has an antibacterial effect on some strains of bacteria such as Sarcina lutea and Bacillus subtilis.

    Formula:C17H20O4S
    Purezza:Min. 95%
    Peso molecolare:320.4 g/mol

    Ref: 3D-GCA03958

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  • L(+)-2-Amino-5-phosphonovaleric acid

    CAS:

    L-2-Amino-5-phosphonovaleric acid is an inhibitory neurotransmitter that binds to the GABAA receptor. It is used in the treatment of bladder disorders, such as urinary frequency, urgency, and incontinence. L-2-Amino-5-phosphonovaleric acid has been shown to have a depressant effect on the central nervous system and can cause symptoms such as nausea, vomiting, and headache. This drug also has antimicrobial properties due to its ability to inhibit bacterial enzyme activities. L-2-Amino-5-phosphonovaleric acid blocks glutamate receptors in mouse hippocampal cells by binding the alpha1 subunit of the GABAA receptor. This prevents the influx of calcium ions into cells and inhibits phosphorylation of protein kinase C. L(+)-2-Amino-5-phosphonovaleric acid also inhibits pentosan polysulfate sodium,

    Formula:C5H12NO5P
    Purezza:Min. 95%
    Peso molecolare:197.13 g/mol

    Ref: 3D-EDA05567

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  • (+/-)N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride

    CAS:
    N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride is a synthetic drug product that has been shown to be metabolized in humans. It is an impurity standard for HPLC and analytical methods. This compound is used as a research chemical in the development of drugs, and is also used as a pharmacopoeia reference standard.
    Formula:C17H18F3NO·HCl
    Purezza:Min. 95%
    Peso molecolare:345.79 g/mol

    Ref: 3D-IM58072

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  • Regorafenib metabolite M2 oxide

    CAS:

    Regorafenib metabolite M2 oxide (M2O) is a cancer drug that is an inhibitor of multikinase. It was developed as a prodrug for regorafenib, which is used to treat patients with metastatic colorectal cancer and has been shown to be effective against other cancers, such as lung and pancreatic cancer. M2O inhibits the efflux of drugs from cells by binding to the transporter protein P-glycoprotein. This prevents the accumulation of toxic concentrations of regorafenib in cells, which are responsible for its side effects, such as diarrhea and liver damage. The uptake of M2O by cells is also inhibited by light and acidic conditions. Oral administration of M2O leads to increased exposure to regorafenib in the body because it is not metabolized by CYP3A4 enzymes.

    Formula:C21H15ClF4N4O4
    Purezza:Min. 95%
    Peso molecolare:498.81 g/mol

    Ref: 3D-IR164114

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  • cis-Tadalafil

    CAS:

    Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

    Formula:C22H19N3O4
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:389.4 g/mol

    Ref: 3D-FT27987

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  • Desfluoro ezetimibe

    CAS:

    Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.

    Formula:C24H22FNO3
    Purezza:Min. 95%
    Colore e forma:White To Off-White Solid
    Peso molecolare:391.43 g/mol

    Ref: 3D-FD21193

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  • Ivermectin impurity I

    CAS:

    Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.

    Formula:C48H74O14
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:875.09 g/mol

    Ref: 3D-II167729

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  • Acarbose Impurity E

    CAS:

    Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

    Purezza:Min. 95%

    Ref: 3D-FA175652

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  • Pramipexole EP Impurity C

    CAS:

    Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.

    Formula:C20H32N6S2
    Purezza:Min. 95%

    Ref: 3D-FP165425

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  • N-Benzyl albuterol

    CAS:

    N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

    Formula:C20H27NO3
    Purezza:Min. 95%
    Peso molecolare:329.4 g/mol

    Ref: 3D-ZAA08503

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  • (3S,4R)-Tofacitinib

    CAS:

    (3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.

    Formula:C16H20N6O
    Purezza:Min. 95%
    Peso molecolare:312.37 g/mol

    Ref: 3D-STB57848

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  • N-Desacetyl thiocolchicoside

    CAS:

    N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.

    Formula:C25H31NO9S
    Purezza:Min. 95%
    Peso molecolare:521.58 g/mol

    Ref: 3D-CHA99181

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  • 3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride

    CAS:

    3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

    Formula:C19H25ClN2O2
    Purezza:Min. 95%
    Peso molecolare:348.9 g/mol

    Ref: 3D-WMD18565

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  • (4-Chlorophenyl)diphenylmethanol

    CAS:

    Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C19H15ClO
    Purezza:Min. 95%
    Peso molecolare:294.8 g/mol

    Ref: 3D-GAA92289

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  • Roflumilast Impurity A

    CAS:

    Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

    Formula:C16H14Cl2N2O3
    Purezza:Min. 95%
    Peso molecolare:353.2 g/mol

    Ref: 3D-IR168438

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  • 2-(2-Amino-5-bromobenzoyl)pyridine

    CAS:

    2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval

    Formula:C12H9BrN2O
    Purezza:Min. 95%
    Peso molecolare:277.12 g/mol

    Ref: 3D-IA17613

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  • Empagliflozin S-furanose

    CAS:

    Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.

    Formula:C23H27ClO7
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:450.91 g/mol

    Ref: 3D-IE181148

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  • Dicyclopropylamine hydrochloride

    CAS:

    Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D

    Formula:C6H11N•HCl
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:133.62 g/mol

    Ref: 3D-FD141573

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  • Ciprofloxacin ep impurity C

    CAS:

    Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

    Formula:C15H16FN3O3
    Purezza:Min. 95%
    Peso molecolare:305.30 g/mol

    Ref: 3D-DEA22212

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  • N-Nitroso dorzolamide


    N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.

    Formula:C10H15N3O5S3
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:353.44 g/mol

    Ref: 3D-IN182764

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  • Piperacilloic acid

    CAS:

    Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

    Formula:C23H29N5O8S
    Purezza:(Elemental Analysis) Min. 90 Area-%
    Colore e forma:Powder
    Peso molecolare:535.57 g/mol

    Ref: 3D-FP27061

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  • Oxacyclohexane open ring tacrolimus

    CAS:

    Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C44H71NO13
    Purezza:Min. 95%
    Peso molecolare:822.04 g/mol

    Ref: 3D-IO183660

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  • Tofacitinib dihydro impurity

    CAS:

    Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.

    Formula:C16H22N6O
    Purezza:Min. 95%
    Peso molecolare:314.39 g/mol

    Ref: 3D-QQC97235

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  • Simvastatin acid

    CAS:

    Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

    Formula:C25H40O6
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:436.58 g/mol

    Ref: 3D-IS63828

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  • Sacubitril Impurity 2

    CAS:

    Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.

    Formula:C24H27NO4
    Purezza:Min. 95%
    Peso molecolare:393.48 g/mol

    Ref: 3D-IS181152

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  • Linagliptin impurity G

    CAS:

    Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.

    Formula:C25H28N8O2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:472.54 g/mol

    Ref: 3D-FA146003

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  • Terbinafine dihydrochloride

    CAS:

    Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

    Formula:C36H40N2
    Purezza:Min. 95%
    Peso molecolare:500.7 g/mol

    Ref: 3D-JMB36523

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  • (S)-Rabeprazole sodium

    CAS:

    (S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

    Formula:C18H21N3O3S•Na
    Purezza:Min. 95%
    Peso molecolare:382.43 g/mol

    Ref: 3D-IR183125

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  • N-Hydroxymethyl Sumatriptan

    CAS:

    N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

    Formula:C15H23N3O3S
    Purezza:Min. 95%
    Peso molecolare:325.43 g/mol

    Ref: 3D-FH175834

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  • Rocuronium Bromide EP Impurity F Bromide

    CAS:
    Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.
    Formula:C34H55N2O4·Br
    Purezza:Min. 95%
    Peso molecolare:635.72 g/mol

    Ref: 3D-IR178405

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  • D-6-Cyano-6-norlysergic acid methyl ester

    CAS:

    Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C17H15N3O2
    Purezza:Min. 95%
    Peso molecolare:293.32 g/mol

    Ref: 3D-FBA33404

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  • Chlorthalidone impurity E

    CAS:

    Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>

    Formula:C14H11ClN2O3S
    Purezza:Min. 95%
    Peso molecolare:322.77 g/mol

    Ref: 3D-IC76330

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  • [Trp(O)25]-Semaglutide


    Semaglutide impurity.

    Formula:C187H291N45O60
    Peso molecolare:4,129.64 g/mol

    Ref: 3D-IS27853

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  • Gly-OH9-Oxytocin

    CAS:

    Oxytocin impurity

    Formula:C43H65N11O13S2
    Peso molecolare:1,008.18 g/mol

    Ref: 3D-IO22698

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  • Triethylene glycol flufenamate

    CAS:

    Etofenamate impurity

    Formula:C20H22F3NO5
    Purezza:Min. 95%
    Colore e forma:Clear Liquid
    Peso molecolare:413.39 g/mol

    Ref: 3D-IT58094

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  • Atorvastatin calcium trihydrate EP Impurity G

    CAS:

    Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.

    Formula:C34H37FN2O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:572.67 g/mol

    Ref: 3D-IA182820

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  • GS 441524 triphosphate

    CAS:

    Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis.  Made to order.

    Formula:C12H12N5O13P3·4Na
    Purezza:(31P-Nmr) Min. 95 Area-%
    Colore e forma:White Powder
    Peso molecolare:531.20 g/mol

    Ref: 3D-FG167050

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