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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • Bupivacaine N-oxide hydrochloride

    CAS:

    Bupivacaine N-oxide is a synthetic local anesthetic drug. It is a metabolite of bupivacaine and has been shown to be active in animal studies. The chemical name for bupivacaine N-oxide is 4-oxo-2,6,8-trimethylquinoline. Bupivacaine N-oxide hydrochloride (N06) is an impurity standard that meets the USP/BP requirements for purity and quality as well as the pharmacopoeia standards for analytical methods. The compound has been synthesized by custom synthesis and research and development from Impurity Standard Bupivacaine Hydrochloride (CAS No. 1796927-05-3). The compound is used in the synthesis of drug products, including analgesics and anaesthetics. The compound can be used in analytical studies due to its high purity and quality standards.

    Formula:C18H29ClN2O2
    Purezza:Min. 95%
    Peso molecolare:340.9 g/mol

    Ref: 3D-WWC92705

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  • Pregabalin inhouse impurity (RS-mme)

    CAS:

    Please enquire for more information about Pregabalin inhouse impurity (RS-mme) including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C11H20O4
    Purezza:Min. 95%
    Peso molecolare:216.27 g/mol

    Ref: 3D-VFA32803

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  • (2S,2R,Trans)-saxagliptin

    CAS:

    (2S,2R,Trans)-saxagliptin is an anti-diabetic drug that belongs to the thiazolidinedione class of drugs. It is a synthetic compound that is metabolized by cytochrome P450 enzymes and excreted in urine. (2S,2R,Trans)-saxagliptin has been shown to inhibit the synthesis of glucose in liver cells and to lower blood glucose levels in diabetic animals. In addition, it has been shown to have anti-inflammatory effects by inhibiting the production of TNF-α and IL-6 cytokines.

    Formula:C18H25N3O2
    Purezza:Min. 95%
    Peso molecolare:315.40 g/mol

    Ref: 3D-PMC26598

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  • Rosuvastatin anhydro lactone

    CAS:

    Rosuvastatin anhydro lactone is a pure chemical compound that is used as an analytical reference standard for high-performance liquid chromatography (HPLC) for the determination of purity and identification of impurities in pharmaceuticals. It is also utilized as a drug development, API impurity, and HPLC standard. Rosuvastatin anhydro lactone is a metabolite of rosuvastatin and is chemically designated as C22H29NO3. The CAS number for rosuvastatin anhydro lactone is 1246665-85-9.

    Formula:C22H24FN3O4S
    Purezza:Min. 95%
    Peso molecolare:445.50 g/mol

    Ref: 3D-WZB66585

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  • N,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide

    CAS:

    N,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide is a drug product that can be used as an analytical reference standard and an impurity standard. It is used in the development of drugs, including synthetic intermediates and metabolites. N,5-Dibenzyl-5-hydroxy-indole-3-glyoxylamide is a natural metabolite. It has been shown to have antihistamine activity and to inhibit prostaglandin synthesis.

    Formula:C24H20N2O3
    Purezza:Min. 95%
    Peso molecolare:384.43 g/mol

    Ref: 3D-CEA75441

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  • 4-Hydoxymethyl-5-methylimidazol

    CAS:

    4-Hydroxymethyl-5-methylimidazol (HMMI) is a corrosion inhibitor that is used in the production of nanomaterials. It has been shown to be an effective treatment for wastewater containing hydrochloric acid and organic solvents. The reaction between HMMI and the acids in wastewater forms a complex that prevents the corrosion of metal surfaces. HMMI can be synthesized by reacting aesculus with formaldehyde in an organic solvent, such as acetone or chloroform, at room temperature. HMMI has also been shown to have antiviral potency and is used in skin care products, such as lotions and shampoos, due to its ability to penetrate the skin barrier. Magnetic resonance spectroscopy (MRS) was used to study the effect of HMMI on skin cells, while electrochemical methods were used to investigate how it inhibits viral activity.

    Formula:C5H8N2O
    Purezza:Min. 95%
    Peso molecolare:112.13 g/mol

    Ref: 3D-IH58266

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  • Albendazole sulfone

    CAS:

    Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.

    Formula:C12H15N3O4S
    Purezza:Min. 95 Area-%
    Colore e forma:Powder
    Peso molecolare:297.33 g/mol

    Ref: 3D-IA17258

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  • Pf 3084014 hydrobromide

    CAS:

    Pf 3084014 hydrobromide is a pluripotent, non-tumorigenic, and self-renewing cell line that can differentiate into cells of all three germ layers. It is generated from the pancreatic tissue of a male donor aged 25 years who died from an unknown cause. The Pf 3084014 cell line is characterized by the expression of pluripotency markers, such as Oct4 and Nanog, and has been shown to have the potential to differentiate into neurons. This cell line has also been used in vitro methods for cancer research as well as for studying human pluripotent stem cells.

    Formula:C27H43Br2F2N5O
    Purezza:Min. 95%
    Peso molecolare:651.5 g/mol

    Ref: 3D-MDD92529

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  • N-Isopropylnoradrenochrome

    CAS:

    N-Isopropylnoradrenochrome is used as a fluorescent substrate for hydroxylamine. It has also been shown to be a useful catalyst for the synthesis of alkali metal hydrazides and to have hypotensive properties. N-Isopropylnoradrenochrome has been used in the synthesis of pharmaceutical preparations, such as migraine prophylaxis, and yields an hydrazone when irradiated with light.

    Formula:C11H13NO3
    Purezza:Min. 95%
    Peso molecolare:207.23 g/mol

    Ref: 3D-DAA73631

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  • Sunitinib impurity G

    CAS:

    Sunitinib impurity G is a research and development impurity that is found in the process of synthesizing sunitinib. Sunitinib impurity G is an analytical standard that is soluble in methanol and is suitable for HPLC analysis. It has been shown to have high purity, excellent stability, and a low level of toxicity.

    Formula:C18H20ClFN4O2
    Purezza:Min. 95%
    Peso molecolare:378.8 g/mol

    Ref: 3D-SYB21661

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  • N-Methyl metribuzin

    CAS:

    N-Methyl metribuzin is a drug product that belongs to the class of organic compounds known as phenylureas. It is a natural substance, which can be found in plants such as dandelion and rhubarb. Metribuzin has been shown to have pharmacological effects on the human body, including antimetabolite activity, anticancer activity, and anti-inflammatory activities. Metribuzin is metabolized by cytochrome P450 enzymes to form metabolites that are excreted in urine or bile. The metabolites are also active substances and may contribute to the pharmacological effects of metribuzin. Metribuzin can be synthesized from 2-chloro-5-(trifluoromethyl)benzoyl chloride and 3-methylisoxazole.
    Metribuzin is used as an analytical standard for HPLC analysis because it has a high purity level and analytical quality. It is also used in

    Formula:C9H16N4OS
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:228.32 g/mol

    Ref: 3D-GCA74245

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  • Ethyl 2-methoxy-5-sulfamoylbenzoate

    CAS:

    Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.

    Formula:C10H13NO5S
    Purezza:Min. 95%
    Peso molecolare:259.28 g/mol

    Ref: 3D-IE140268

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  • 2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid

    CAS:
    2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.
    Formula:C19H29O6P
    Purezza:Min. 95%
    Peso molecolare:384.4 g/mol

    Ref: 3D-IM27637

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  • (trans)-4-Propyl-1-methyl-L-proline

    CAS:

    (trans)-4-Propyl-1-methyl-L-proline is a synthetic compound that has been used in the past as an impurity standard in the synthesis of several drugs, including metaxalone and aminopyrine. It is also found to have pharmacological effects on its own and was used as a drug product for the treatment of rheumatoid arthritis. (trans)-4-Propyl-1-methyl-L-proline is not listed in any pharmacopoeia or international list of approved drugs.

    Formula:C9H17NO2
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:171.24 g/mol

    Ref: 3D-FP27224

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  • Bendamustine isopropyl ester

    CAS:

    Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.

    Formula:C19H27Cl2N3O2
    Purezza:Min. 95%
    Peso molecolare:400.30 g/mol

    Ref: 3D-NCC02025

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  • (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol

    Prodotto controllato
    CAS:

    Please enquire for more information about (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C9H13NO2
    Purezza:Min. 95%
    Peso molecolare:167.2 g/mol

    Ref: 3D-WAA48043

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  • Olsalazine sodium EP impurity F


    Olsalazine sodium EP impurity F
    CAS No.:
    Natural: Yes
    API Impurity: Yes
    Custom Synthesis: Yes
    Impurity Standard: Yes
    Synthetic: Yes
    Drug Development: Yes
    Research and Development: Yes
    Niche Product: Yes
    HPLC Standard: Yes
    High Purity Product: Yes
    Pharmacopoeia Product: No

    Formula:C21H14N2O9
    Purezza:Min. 95%
    Peso molecolare:438.34 g/mol

    Ref: 3D-IO63799

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  • (E)-4-Alloxycarboxyl tamoxifen

    CAS:

    (E)-4-Alloxycarboxyl tamoxifen is a synthetic metabolite of tamoxifen. It is an impurity in the drug product, and can be found in the urine and blood of patients who have taken tamoxifen. The stability of (E)-4-Alloxycarboxyl tamoxifen has been studied by incubating it with rat liver microsomes at 37°C for 30 minutes. Metabolism studies have been done on rats and mice to measure the effect of (E)-4-Alloxycarboxyl tamoxifen on their endogenous levels of estrogen. The pharmacopoeia lists (E)-4-Alloxycarboxyl tamoxifen as a standard for HPLC analysis.

    Formula:C30H33NO4
    Purezza:Min. 95%
    Peso molecolare:471.60 g/mol

    Ref: 3D-MBC19158

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  • (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

    CAS:

    (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.

    Formula:C15H15N
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:209.29 g/mol

    Ref: 3D-IP46848

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  • Alloc bromoridane

    CAS:

    Alloc bromoridane is a drug product that contains the active ingredient bromoridane. Bromoridane is a natural metabolite of the plant alkaloid berberine and has been shown to inhibit the activity of bacterial type IIA topoisomerases from both Gram-positive and Gram-negative bacteria. The chemical name for Alloc bromoridane is 2-[2-(4-bromobenzoyl)phenyl]dihydropyrimidine, and it has CAS number 117348-70-6. Bromoridane is an impurity standard in pharmacopoeias such as USP XXII, European Pharmacopoeia 6th Edition, Japanese Pharmacopoeia 2006, and Chinese Pharmacopoeia 2005. Alloc bromoridane is used in research and development for pharmaceuticals or as an analytical reference material.

    Formula:C13H20BrNO4
    Purezza:Min. 95%
    Peso molecolare:334.21 g/mol

    Ref: 3D-SEA34870

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  • 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid

    CAS:

    1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.

    Formula:C8H11N3O5
    Purezza:Min. 95%
    Peso molecolare:229.19 g/mol

    Ref: 3D-IR138822

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  • Omeprazole Impurity 65


    Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.

    Formula:C17H17N3O4
    Purezza:Min. 95%
    Peso molecolare:327.33 g/mol

    Ref: 3D-IE177230

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  • 7-O-methyl ivermectin B1a


    7-O-methyl ivermectin is a drug product that is an analytical standard for the impurity 7-O-methyl ivermectin B1a. Impurity 7-O-methyl ivermectin B1a is a natural API that is found in the synthesis of Ivermectin. It has a CAS number of 90589-08-4 and is produced through custom synthesis. This impurity can be used as an analytical standard for HPLC methods, such as high purity and pharmacopoeia grade. 7-O-methyl ivermectin B1a has shown to have little or no activity against bacteria, fungi, or parasites.

    Purezza:Min. 95%

    Ref: 3D-IO167868

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  • DL-threo-Ritalinic acid

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    CAS:

    DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.

    Formula:C13H17NO2
    Purezza:Min. 95%
    Peso molecolare:219.28 g/mol

    Ref: 3D-IR180350

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  • Torasemide EP Impurity C

    CAS:

    Torasemide EP Impurity C is a drug product that is used as an analytical standard in the metabolism studies of torasemide. Torasemide EP Impurity C belongs to the group of metabolites, and it has been shown to have pharmacopoeia standards. Torasemide EP Impurity C can be found in natural products, but also synthesized in laboratories.

    Formula:C15H18N4O3S
    Purezza:Min. 95%
    Peso molecolare:334.39 g/mol

    Ref: 3D-IT177756

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  • Fonofos

    CAS:

    Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.

    Formula:C10H15OPS2
    Purezza:Min. 95%
    Peso molecolare:246.3 g/mol

    Ref: 3D-AAA94422

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  • L(+)-2-Amino-5-phosphonovaleric acid

    CAS:

    L-2-Amino-5-phosphonovaleric acid is an inhibitory neurotransmitter that binds to the GABAA receptor. It is used in the treatment of bladder disorders, such as urinary frequency, urgency, and incontinence. L-2-Amino-5-phosphonovaleric acid has been shown to have a depressant effect on the central nervous system and can cause symptoms such as nausea, vomiting, and headache. This drug also has antimicrobial properties due to its ability to inhibit bacterial enzyme activities. L-2-Amino-5-phosphonovaleric acid blocks glutamate receptors in mouse hippocampal cells by binding the alpha1 subunit of the GABAA receptor. This prevents the influx of calcium ions into cells and inhibits phosphorylation of protein kinase C. L(+)-2-Amino-5-phosphonovaleric acid also inhibits pentosan polysulfate sodium,

    Formula:C5H12NO5P
    Purezza:Min. 95%
    Peso molecolare:197.13 g/mol

    Ref: 3D-EDA05567

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  • Steptonigrin

    CAS:

    Streptonigrin is an anticancer drug that is derived from the bacterium Streptomyces flocculus. It has been shown to induce apoptosis in cancer cells by inhibiting various kinases, including cyclin-dependent kinases and protein kinases. Streptonigrin has been found to be effective against a variety of tumors, including those of Chinese hamster ovary cells and human urine-derived cancer cells. This inhibitor analog also has a potent inhibitory effect on tumor growth in vivo.

    Formula:C25H22N4O8
    Purezza:Min. 95%
    Peso molecolare:506.5 g/mol

    Ref: 3D-ETB89379

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  • Haloxyfop-d4

    CAS:

    Haloxyfop-d4 is an analog of the herbicide Haloxyfop that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a key role in cell division and growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Haloxyfop-d4 has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer drugs. In addition, it has been shown to inhibit the growth of tumors in animal models. This drug is metabolized in the liver and excreted in urine. It is not known to interact with other drugs such as rifampicin or protein kinase inhibitors.

    Formula:C15H11ClF3NO4
    Purezza:Min. 95%
    Peso molecolare:365.72 g/mol

    Ref: 3D-CFA89334

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  • RS 67506 hydrochloride

    CAS:

    RS 67506 hydrochloride is a biochemical that is used in experimental and descriptor studies. The ketone group has been found to be an important part of the molecular structure. RS 67506 hydrochloride has been shown to have a number of biological properties, including inhibition of the synthesis of neurotransmitters such as dopamine, serotonin and norepinephrine; it also has anti-nervous system activity. This chemical was also found to inhibit the synthesis of prostaglandin E2 in human neutrophils. It is hypothesized that RS 67506 hydrochloride may inhibit phospholipase A2, which would prevent the release of arachidonic acid from phospholipids into the cell membrane and block the production of eicosanoids.

    Formula:C18H29Cl2N3O4S
    Purezza:Min. 95%
    Peso molecolare:454.4 g/mol

    Ref: 3D-TGA98661

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  • Cyamemazine sulfoxide

    CAS:

    Cyamemazine sulfoxide is a histamine H1 receptor antagonist. It has been shown to have strong affinity for the serotonin 5-HT2C and dopamine D2 receptors, as well as the atrial 5-HT2A receptors. Cyamemazine sulfoxide has a low oral bioavailability of about 10% and is metabolized in the liver to cyamemazine and its active form, cyamemazine sulfoxide. Cyamemazine sulfoxide binds to serotonin 5-HT2C receptors with a high affinity, which leads to inhibition of serotonin release from nerve endings in the brain. This drug also inhibits dopamine release from nerve endings in the brain and has been shown to have cardiac effects on heart rate and contractility.

    Formula:C19H21N3OS
    Purezza:Min. 95%
    Peso molecolare:339.46 g/mol

    Ref: 3D-FC20596

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  • N-Methyl formoterol fumarate

    CAS:

    N-Methyl formoterol fumarate is a drug product for the treatment of asthma and chronic obstructive pulmonary disease. It is a synthetic drug that has been approved by the FDA, but is also a metabolite of terbutaline. Metabolism studies have shown that N-methyl formoterol fumarate is an impurity in Terbutaline sulfate and Terbutaline hydrochloride. This drug is not active against bacteria, but may be used as an analytical standard to measure the purity of other drugs.

    Formula:C44H56N4O12
    Purezza:Min. 95%
    Peso molecolare:832.94 g/mol

    Ref: 3D-VWC13397

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  • Way 629 hydrochloride

    CAS:

    Way 629 hydrochloride is a chemical compound that belongs to the class of synthetic, pharmacopoeia and drug development. It is used as an impurity standard and a custom synthesis. Way 629 hydrochloride is also used in the study of metabolism. This compound has been shown to be metabolized by cytochrome P450 enzymes, glucuronidases, glutathione reductase, or conjugation with glucuronic acid.

    Formula:C15H19ClN2
    Purezza:Min. 95%
    Peso molecolare:262.78 g/mol

    Ref: 3D-HCA75644

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  • Carfilzomib (2R,4S)-diol

    CAS:

    Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.

    Formula:C40H59N5O8
    Purezza:Min. 95%
    Peso molecolare:737.90 g/mol

    Ref: 3D-RLC17275

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  • Spirolaxine

    CAS:

    Spirolaxine is a coumarin derivative that has been shown to have anti-cancer properties. It was isolated from an extract of the fungus Spirolaxine, which was found in the gastroduodenum (gut) of a frog. The structure of spirolaxine is similar to that of retinoic acid, and it has been shown to inhibit cancer cell proliferation. Spirolaxine also inhibits the production of proinflammatory cytokines in mice with colitis. This drug has not yet been tested for its ability to treat other diseases, such as diabetes, but may be able to regulate blood sugar levels by inhibiting insulin secretion and increasing glucose uptake by cells.

    Formula:C23H32O6
    Purezza:Min. 95%
    Peso molecolare:404.5 g/mol

    Ref: 3D-BFA38201

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  • cis-Tadalafil

    CAS:

    Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

    Formula:C22H19N3O4
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:389.4 g/mol

    Ref: 3D-FT27987

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  • Piperacilloic acid

    CAS:

    Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

    Formula:C23H29N5O8S
    Purezza:(Elemental Analysis) Min. 90 Area-%
    Colore e forma:Powder
    Peso molecolare:535.57 g/mol

    Ref: 3D-FP27061

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  • Terbinafine dihydrochloride

    CAS:

    Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

    Formula:C36H40N2
    Purezza:Min. 95%
    Peso molecolare:500.7 g/mol

    Ref: 3D-JMB36523

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  • N-Desacetyl thiocolchicoside

    CAS:

    N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.

    Formula:C25H31NO9S
    Purezza:Min. 95%
    Peso molecolare:521.58 g/mol

    Ref: 3D-CHA99181

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  • Simvastatin acid

    CAS:

    Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

    Formula:C25H40O6
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:436.58 g/mol

    Ref: 3D-IS63828

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  • Empagliflozin S-furanose

    CAS:

    Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.

    Formula:C23H27ClO7
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:450.91 g/mol

    Ref: 3D-IE181148

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  • 3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride

    CAS:

    3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

    Formula:C19H25ClN2O2
    Purezza:Min. 95%
    Peso molecolare:348.9 g/mol

    Ref: 3D-WMD18565

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  • Oxacyclohexane open ring tacrolimus

    CAS:

    Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C44H71NO13
    Purezza:Min. 95%
    Peso molecolare:822.04 g/mol

    Ref: 3D-IO183660

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  • Sacubitril Impurity 2

    CAS:

    Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.

    Formula:C24H27NO4
    Purezza:Min. 95%
    Peso molecolare:393.48 g/mol

    Ref: 3D-IS181152

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  • Pramipexole EP Impurity C

    CAS:

    Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.

    Formula:C20H32N6S2
    Purezza:Min. 95%

    Ref: 3D-FP165425

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  • (S)-Rabeprazole sodium

    CAS:

    (S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

    Formula:C18H21N3O3S•Na
    Purezza:Min. 95%
    Peso molecolare:382.43 g/mol

    Ref: 3D-IR183125

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  • Ivermectin impurity I

    CAS:

    Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.

    Formula:C48H74O14
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:875.09 g/mol

    Ref: 3D-II167729

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  • (4-Chlorophenyl)diphenylmethanol

    CAS:

    Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C19H15ClO
    Purezza:Min. 95%
    Peso molecolare:294.8 g/mol

    Ref: 3D-GAA92289

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  • N-Nitroso dorzolamide


    N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.

    Formula:C10H15N3O5S3
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:353.44 g/mol

    Ref: 3D-IN182764

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  • 2-(2-Amino-5-bromobenzoyl)pyridine

    CAS:

    2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval

    Formula:C12H9BrN2O
    Purezza:Min. 95%
    Peso molecolare:277.12 g/mol

    Ref: 3D-IA17613

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  • Linagliptin impurity G

    CAS:

    Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.

    Formula:C25H28N8O2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:472.54 g/mol

    Ref: 3D-FA146003

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  • Acarbose Impurity E

    CAS:

    Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

    Purezza:Min. 95%

    Ref: 3D-FA175652

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  • Rocuronium Bromide EP Impurity F Bromide

    CAS:
    Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.
    Formula:C34H55N2O4·Br
    Purezza:Min. 95%
    Peso molecolare:635.72 g/mol

    Ref: 3D-IR178405

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  • N-Hydroxymethyl Sumatriptan

    CAS:

    N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

    Formula:C15H23N3O3S
    Purezza:Min. 95%
    Peso molecolare:325.43 g/mol

    Ref: 3D-FH175834

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  • Roflumilast Impurity A

    CAS:

    Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

    Formula:C16H14Cl2N2O3
    Purezza:Min. 95%
    Peso molecolare:353.2 g/mol

    Ref: 3D-IR168438

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  • Ciprofloxacin ep impurity C

    CAS:

    Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

    Formula:C15H16FN3O3
    Purezza:Min. 95%
    Peso molecolare:305.30 g/mol

    Ref: 3D-DEA22212

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  • (3S,4R)-Tofacitinib

    CAS:

    (3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.

    Formula:C16H20N6O
    Purezza:Min. 95%
    Peso molecolare:312.37 g/mol

    Ref: 3D-STB57848

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  • Desfluoro ezetimibe

    CAS:

    Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.

    Formula:C24H22FNO3
    Purezza:Min. 95%
    Colore e forma:White To Off-White Solid
    Peso molecolare:391.43 g/mol

    Ref: 3D-FD21193

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  • Tofacitinib dihydro impurity

    CAS:

    Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.

    Formula:C16H22N6O
    Purezza:Min. 95%
    Peso molecolare:314.39 g/mol

    Ref: 3D-QQC97235

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  • Dicyclopropylamine hydrochloride

    CAS:

    Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D

    Formula:C6H11N•HCl
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:133.62 g/mol

    Ref: 3D-FD141573

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  • N-Benzyl albuterol

    CAS:

    N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

    Formula:C20H27NO3
    Purezza:Min. 95%
    Peso molecolare:329.4 g/mol

    Ref: 3D-ZAA08503

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  • Chlorthalidone impurity E

    CAS:

    Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>

    Formula:C14H11ClN2O3S
    Purezza:Min. 95%
    Peso molecolare:322.77 g/mol

    Ref: 3D-IC76330

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  • [Trp(O)25]-Semaglutide


    Semaglutide impurity.

    Formula:C187H291N45O60
    Peso molecolare:4,129.64 g/mol

    Ref: 3D-IS27853

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  • Gly-OH9-Oxytocin

    CAS:

    Oxytocin impurity

    Formula:C43H65N11O13S2
    Peso molecolare:1,008.18 g/mol

    Ref: 3D-IO22698

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  • Triethylene glycol flufenamate

    CAS:

    Etofenamate impurity

    Formula:C20H22F3NO5
    Purezza:Min. 95%
    Colore e forma:Clear Liquid
    Peso molecolare:413.39 g/mol

    Ref: 3D-IT58094

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  • D-6-Cyano-6-norlysergic acid methyl ester

    CAS:

    Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C17H15N3O2
    Purezza:Min. 95%
    Peso molecolare:293.32 g/mol

    Ref: 3D-FBA33404

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  • GS 441524 triphosphate

    CAS:

    Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis.  Made to order.

    Formula:C12H12N5O13P3·4Na
    Purezza:(31P-Nmr) Min. 95 Area-%
    Colore e forma:White Powder
    Peso molecolare:531.20 g/mol

    Ref: 3D-FG167050

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  • Atorvastatin calcium trihydrate EP Impurity G

    CAS:

    Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.

    Formula:C34H37FN2O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:572.67 g/mol

    Ref: 3D-IA182820

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