APIs per la ricerca e le impurità

<p>Scopolamine is a muscarinic antagonist that is used to prevent motion sickness and the nausea and vomiting associated with anesthesia. It is an ester of scopolamine with hydrobromic acid. Scopolamine hydrobromide has been shown to have similar effects on humans as it does on rats. It is absorbed through the skin and metabolized in the liver, where it is excreted in bile and eliminated through the urinary system. The elimination half-life of scopolamine hydrobromide in humans ranges from 1 to 3 hours, which means that its effects wear off after about three hours.</p>

<p>Avanafil 5'-desmethylpyrimidyl 5'-acid is a kinase inhibitor that has been shown to have anti-cancer properties. It inhibits kinases, which are enzymes involved in cell signaling pathways, and has been shown to inhibit the growth of cancer cells in vitro. Avanafil 5'-desmethylpyrimidyl 5'-acid may be used in combination with other drugs, such as rifampicin or methotrexate, for the treatment of cancer. Additionally, it has been found to induce apoptosis (programmed cell death) in human tumor cells. Chinese medicine has also used avanafil 5'-desmethylpyrimidyl 5'-acid analogs such as astaxanthin for its health benefits. This drug is excreted primarily through urine and shows promise as a potential inhibitor for various diseases.</p>

<p>Hydroxyvarenicline N-oxide is a drug product with a purity of 98.0%. It is an analytical standard used in metabolism studies, drug development, and pharmacopoeia. It has been shown to be metabolized by CYP450 enzymes to form its metabolite hydroxyvarenicline N-oxide sulfate. The CAS number for this compound is 2306217-11-6.</p>

<p>NMP-ACA is a metabolite of cefepime. It is a synthetic, impurity standard for use in HPLC. It has an analytical purity of &gt;98%. The metabolites of NMP-ACA are not known at this time.</p>

Tamsulosin sulfonic acid is a drug product that belongs to the class of synthetic drugs and is used for the treatment of urinary tract disorders. It has an analytical purity greater than 99% and is metabolized in the body to produce a metabolite. Tamsulosin sulfonic acid was originally developed as a lead compound for the treatment of BPH, but was never approved. Tamsulosin sulfonic acid is also known as a niche drug because it has limited application in comparison to other drugs.

<p>N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine is a custom synthesis that has a CAS number of 1408238-37-8. This product is for research and development, HPLC standard, impurity standard, metabolite, natural, niche, and synthetic. N-[2-[4-(hexyloxy)anilinocarbonylamino]-1-(methyl)-1H benzimidazol--5--yl]carbonyl -N-[2-(pyridinyl)]alanine is a metabolite of this product. It has been synthesized by the drug development department in order to use it as an analytical standard for HPLC. The following are some</p>

<p>Please enquire for more information about N-Desmethyl eletriptan hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Loxoprofen Related Compound 2 is a mixture of diastereomers that is an impurity in the drug product, Loxoprofen. Loxoprofen Related Compound 2 is a metabolite of loxoprofen and its concentration in blood plasma after administration of loxoprofen can be used as an indicator for pharmacokinetics. The compound has been shown to inhibit the activity of bacterial dna gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. Loxoprofen Related Compound 2 was found to be less active than loxoprofen against MRSA and Clostridium perfringens, although it was more active than loxoprofen against Mycobacterium tuberculosis, Mycobacterium avium complex, and methicillin-resistant Staphylococcus aureus (MRSA).</p>

<p>6-[2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-3-pyridineacetic acid is a drug product that has been custom synthesized by our in-house chemists. It is a high purity chemical with an analytical purity of 98%. It is also CAS No. 146062-48-8 and can be found in the pharmacopoeia. This compound has been studied for metabolism studies and drug development. The metabolite is natural and its impurity standard is met by HPLC standards.</p>

<p>Desoximetasone impurity A is an impurity found in the drug product Desoximetasone, which is a corticosteroid. It has been identified as an impurity in the drug product and there are no known uses of Desoximetasone impurity A. This impurity was determined to be natural based on its molecular weight, infrared spectrum, melting point, and elemental analysis. The molecular weight for Desoximetasone impurity A is 687.2 g/mol with a melting point at 89°C and an elemental analysis of Carbon: 29%, Hydrogen: 3%, Nitrogen: 16%, Oxygen: 32%.</p>

<p>6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.</p>

<p>Please enquire for more information about [p-(Benzyloxy)phenyl]acetic acid tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dehydro trimipramine is a metabolite of the antidepressant drug trimipramine. It is used as an analytical standard in HPLC and as an impurity standard in pharmacopoeias. Dehydro trimipramine has been shown to inhibit the metabolism of other drugs, such as phenytoin, by cytochrome P450 enzymes. This inhibition can lead to increased levels of active metabolites and may lead to toxicity or side effects for these drugs.</p>

<p>Please enquire for more information about VU 0465350 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>9,10-Dioxo ketotifen is a drug product that belongs to the category of HPLC standards. It has been shown to be a metabolite of ketotifen and also an impurity in ketotifen. 9,10-Dioxo ketotifen has been shown to possess antihistamine activity and may have potential as a lead compound for the development of new drugs.</p>

<p>Please enquire for more information about 5-Chloro-N-4-pyridinyl-2,1-benzisothiazole-3-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Remdesivir impurity 8 is a metabolite of remdesivir, a drug product that belongs to the class of synthetic compounds. Remdesivir impurity 8 has been used as a research and development standard for HPLC analysis. It is also used as an impurity standard in pharmacopoeia and drug development. This impurity has shown natural activity in metabolism studies, but it is not known if this activity is due to the compound itself or an artifact from its synthesis.</p>

<p>The ethylene terephthalate cyclic pentamer is a polyester that is used in the manufacture of polyester fibers and polyester films. It is extracted from the raw material, which is a mixture of dimethyl terephthalate, ethylene glycol, and 1,4-butanediol. The extruder heats the raw material to 240°C in order to convert it into its liquid form. The crystallization process takes place at room temperature and produces a white solid product called oligomer. Extraction removes impurities from the oligomer by washing it with water. Linear polyester is obtained by heating the purified oligomer at 260°C for 40 minutes, while extruded polyester undergoes a heat treatment of 230°C for 20 minutes. Extrusion produces pellets that are then processed into filaments or sheets.</p>

<p>Remdesivir related compound 9 is a drug product that is an analytical standard. It is a natural API impurity, which has been synthesized for use as an impurity standard. This compound has been custom synthesized to be used as a research and development chemical. CAS No. 1439900-56-7 is the number of this synthetic drug product. It can be used in HPLC standards and it meets pharmacopoeia requirements for purity. The niche market for this compound is high purity analytical standards, including HPLC standards.</p>

<p>Please enquire for more information about Exo-tropine-3-thiol hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3,4-Di-o-benzyl droxidopa-13C2,15N hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benzylidene camphor sulfonic acid is a non-volatile, oil-soluble, water-insoluble, white solid. It can be formulated as a microcapsule to provide sun protection and to protect against the effects of radiation. Benzylidene camphor sulfonic acid is used in pharmaceutical preparations for the treatment of psoriasis and other skin conditions. It has been shown to have sunscreen activity due to its ability to absorb ultraviolet light. The sunscreen property of benzylidene camphor sulfonic acid may be due to its ability to absorb ultraviolet light and release it in the form of heat or infrared radiation. Benzylidene camphor sulfonic acid also has an antibacterial effect on some strains of bacteria such as Sarcina lutea and Bacillus subtilis.</p>

<p>Piquindone is a medicinal compound that has shown promising anticancer properties in human tumor cells. It acts as an inhibitor of protein kinases, which are enzymes that regulate cell growth and division. Piquindone is an analog of a natural product found in Chinese urine and has been studied for its ability to induce apoptosis, or programmed cell death, in cancer cells. This compound has shown potent activity against various types of cancer cells and may have potential as a therapeutic agent for the treatment of cancer. Its mechanism of action involves the inhibition of specific kinases involved in cancer cell proliferation and survival. Piquindone is being investigated further for its potential as a cancer cell inhibitor.</p>

<p>1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.</p>

<p>Racemic 2-amino-2-(hydroxymethyl)propane-3-ol-1-yl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate) is a synthetic drug product. It is used in research and development as an impurity standard. It is also used to synthesize drug products, which are custom synthesis and not commercially available. The racemate is a metabolite of the natural compound "Lysergic acid" and has been studied for its effects on metabolism.</p>

<p>Please enquire for more information about 3-Bromo-N-desethyl-N-benzyl lidocaine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester is a drug product that belongs to the class of Custom synthesis. It is a metabolite of loratadine, an antihistamine drug. The compound is a metabolite of loratadine, which is an antihistamine drug used for the treatment of allergies. It is produced by the oxidation of loratadine by cytochrome P450 enzymes and can be detected in urine at concentrations up to 5 ng/mL. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester has been shown to be effective in inhibiting the growth of bacteria that are resistant to penicillin and erythromycin.</p>

<p>Oxybutynin EP impurity A is a metabolite of oxybutynin, an antispasmodic drug. It has been shown to have immunomodulatory effects in a rat model of adjuvant arthritis. Oxybutynin EP impurity A is the major metabolite of oxybutynin and has been shown to be pharmacologically active in humans.</p>

<p>6-Ethenyl-3-methyl-4-phenyl-2-pyridinecarboxylic acid methyl ester is an impurity standard for use in the drug product formulation and development of drugs. It is a synthetic, high purity, pharmacopoeia grade chemical that can be used as an analytical reference standard for HPLC. 6-Ethenyl-3-methyl-4-phenyl-2-pyridinecarboxylic acid methyl ester is a metabolite of nicotinamide and has been studied extensively by metabolism studies.</p>

<p>(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.</p>

<p>Polyethylene glycol monoisotridecyl ether (PEG-DTAE) is a polymer that can be used as an antimicrobial agent. It is active against Gram-positive bacteria but not against Gram-negative bacteria. PEG-DTAE has anti-angiogenic effects, which may be due to its ability to inhibit the growth of new blood vessels and thereby prevent the spread of infection. In vitro assays have shown that PEG-DTAE can induce cell lysis and hemolysis in test samples. PEG-DTAE has been shown to have hemolytic activity in vivo in rats, with histology sections showing inflammation and necrosis in the spleen and liver. This polymer also causes symptoms such as fever, chills, rigors, and hypotension in patients with chronic renal failure who are undergoing dialysis.</p>

<p>Everolimus related compound 3 is a chemical compound that contains xylose, chamomile extract, cellulose, sulfadiazine, and other ingredients. It is commonly used in industrial applications and has various properties and uses. This compound has been found to have interactions with glutamate, basic proteins, tocopherol, biomass, ticagrelor, chemokines, P. aeruginosa, and other substances. It may also contain impurities such as growth factors and fatty acids. Its specific applications and benefits will depend on the intended use in different industries.</p>

<p>Torasemide EP Impurity D is a drug product or impurity. It is an analytical standard for purity testing of torasemide. Torasemide EP Impurity D is also a metabolite of torasemide and can be found in urine as well as other tissues. It is natural, but not naturally occurring. Research and Development studies of this impurity are ongoing to determine its pharmacological activity and niche applications.</p>

<p>Vu 0469650 hydrochloride is a white to off-white, crystalline powder. It is a synthetic compound that is used as an impurity standard and custom synthesis. Vu 0469650 hydrochloride has been shown to be stable in biological fluids and tissues, such as plasma, urine, bile, and brain tissue. The purity of this drug product can be determined through HPLC analysis.</p>

<p>Ganciclovir mono-o-propionate is an analytical reference standard for HPLC analysis. It is also a drug development intermediate, an API impurity, and a metabolite of ganciclovir. Ganciclovir mono-o-propionate is a crystalline solid with a melting point of 119°C and a molecular weight of 312.5. This compound can be found in the USP/NF (2009) as an impurity in the ganciclovir product. Ganciclovir mono-o-propionate has been used by companies to synthesize ganciclovir or other analogues for research purposes. The natural form of this compound can be found in plants such as apple leaves and grape leaves, but it can also be synthesized from chloroacetic acid and propionic acid.</p>

<p>Naltrexone Impurity G is a synthetic impurity found in naltrexone. It is used as an impurity standard and can be custom synthesized to meet the needs of researchers, developers, and manufacturers of drug products. Naltrexone Impurity G is a metabolite that has been shown to have pharmacological effects similar to those of naltrexone. It is used in metabolism studies. Naltrexone Impurity G has a purity level of 99% or higher and can be ordered as a methanol solution or powder.</p>

<p>Ornidazole-hydroxy is a drug product that is manufactured using HPLC. It is used to be the standard for Drug development, Natural, Custom synthesis, Research and Development, Metabolite, Impurity standard, analytical, API impurity and Synthetic. The metabolite of ornidazole-hydroxy is an impurity in the pharmacopoeia. Ornidazole-hydroxy has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ornithine decarboxylase. Ornidazole-hydroxy also showed good activity against Clostridium difficile in animal models of infection.</p>

<p>Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.</p>

<p>Ajoene is a natural compound that has been shown to have antimicrobial properties, as well as an ability to inhibit the growth of tumor cells. Ajoene is also a potent inhibitor of dextran sulfate proteoglycan synthesis in vitro and has been shown to produce a hypoglycemic effect in vivo. Ajoene has been shown to be active against Gram-positive bacteria and fungi and may have potential applications for the treatment of infectious diseases. Further research is needed to determine whether ajoene may be used as an antioxidant or neuroprotective agent.</p>

<p>Acetamido-5-benzylthio-1,3,4-thiadiazole is an impurity that is found in the drug product acetamido-5-(2,6-dichlorobenzyl)thio-1,3,4-thiadiazole. It has been used as an analytical standard for HPLC and as a pharmacopoeia impurity standard. Acetamido-5-benzylthio-1,3,4-thiadiazole is also a metabolite of acetamido-5-(2,6 dichlorobenzyl)thio-1,3,4 thiadiazole. This compound has been detected in natural sources such as plants and animals. Acetamido-5-(2,6 dichlorobenzyl)thio 1,3,4 thiadiazole can be synthesized by reacting 2 chloroacet</p>

<p>Scirpentriol is an analog of a compound found in Chinese herbal medicine that has been shown to have potent anticancer activity. It inhibits cyclin-dependent kinases, which are enzymes involved in regulating the cell cycle and proliferation. Scirpentriol has been shown to induce apoptosis, or programmed cell death, in human cancer cells. This compound also inhibits the activity of certain protein kinases that are involved in tumor growth, making it a promising candidate for the development of new cancer therapies. Scirpentriol has potential as an inhibitor of urinary tract tumors due to its ability to block kinase activity and promote apoptosis.</p>

<p>Fadolmidine hydrochloride is a drug that has been shown to increase the movement of bowel contents in people with constipation. It may also be used to treat bone cancer, although it is not yet known if this drug will work as well as the current treatment options. Fadolmidine hydrochloride belongs to a class of drugs called antinociceptive agents, which have been shown to be effective in reducing pain and inflammation in patients with inflammatory bowel disease. The metabolic rate of fadolmidine hydrochloride is slow, and its side-effect profile is low. Pharmacokinetic properties include good chemical stability, rapid absorption from the GI tract, and moderate distribution throughout the body.</p>

<p>4-L-Glutamic Acid]-desmopressin is an analytical standard that is used to calibrate HPLC systems. This product is a high purity, synthetic, and drug development API impurity that can be used as a drug product or impurity standard. It is also available as an HPLC standard, niche, and custom synthesis. 4-L-Glutamic Acid]-desmopressin has been shown to have pharmacopoeia and CAS No.</p>

<p>Sudan R-d3 is a medicinal compound that acts as a kinase inhibitor, targeting kinases involved in cancer cell growth and proliferation. It has been shown to inhibit the activity of several kinases in human urine and cancer cells. Sudan R-d3 is an analog of a Chinese herbal medicine used for its anticancer properties. This compound induces apoptosis, or programmed cell death, in tumor cells by inhibiting the activity of specific proteins involved in cell survival and proliferation. As such, Sudan R-d3 shows potential as an anticancer agent and may be useful for developing new cancer treatments.</p>

<p>Please enquire for more information about 4-(Diphenylmethylene)-1-methylpiperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Oxo atorvastatin is an impurity standard for atorvastatin. It is a synthetic metabolite that has been observed in the urine of patients receiving atorvastatin. 5-Oxo atorvastatin can be used as a reference compound to calibrate HPLC measurements and as an analytical standard in pharmacopoeia testing.</p>

<p>Please enquire for more information about rac Clavam-2-carboxylic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Descyclopropyl-2-oxopropyl prasugrel is a metabolite of the prodrug prasugrel. It is a synthetic compound that has been shown to have pharmacological activity similar to its parent drug. Descyclopropyl-2-oxopropyl prasugrel has a purity of &gt;98% and is available as an API standard in impurity grade and as custom synthesis. The chemical name for descyclopropyl-2-oxopropyl prasugrel is 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2- yl)butoxy]-N-(3S)-(3aR*,8aS*)-octahydroindole-1,3(2H)-dione.</p>

Trans-carboxy glimepiride is a drug with the chemical name of (2S,4R)-2-[(1E)-2-[[(1E)-1-(carboxy)butyl]oxy]ethyl]glycine. It is an impurity found in the drug product Glimepiride. The impurity standard for trans-carboxy glimepiride is prepared by dissolving 1 g of the substance in water and diluting to 10 mL with water. It is used as an HPLC standard and has been shown to be a metabolite of Glimepiride.

<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>

<p>Alverine EP Impurity C is a by-product of the synthesis of alverine, which is an ammonium salt. The process involves the use of high yield, high purity triflic acid, and organic solvents. The reaction system is typically carried out in a solvent such as toluene or dichloromethane. The organic solvent is then removed by filtration and the desired product can be obtained by crystallization or recrystallization. Alverine EP Impurity C has been shown to have insecticidal properties when applied externally, due to its interaction with insect stereoisomers. It also has anticancer activity and may be used in cancer therapy treatments that involve decompressing tumours and increasing blood supply to the area. Alverine EP Impurity C also has a citric acid binding property that makes it insoluble in water.</p>

<p>2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a research and development impurity standard. Impurities are the substances that are not intentionally added to the drug product but can be generated from the synthesis process or from the raw materials. This substance has been used as a synthetic intermediate in the production of other drugs and as an analytical reference for HPLC analysis. It is used to help develop new drugs by providing data about metabolites and possible toxic effects on humans.</p>

<p>2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a drug product that is used as an analytical reference standard for the metabolism studies of acetaminophen. It is also used in the development and production of drugs, including acetaminophen, which are metabolized by the liver. 2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a white crystalline solid with a melting point of about 220°C. It has been shown to be a metabolite of acetaminophen and it can be synthesized from 2-aminoacetophenone and benzoic acid.</p>

<p>Please enquire for more information about Benzilic acid 1-ethyl-3-pyrrolidinyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(-)-Nefopam is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in many cellular processes. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, or programmed cell death. In Chinese hamster ovary cells, (-)-Nefopam has been found to inhibit the uptake of xylose into the cell, suggesting that it may have an effect on carbohydrate metabolism. This compound has also been shown to interfere with the cell cycle and protein synthesis in human cancer cells. Overall, (-)-Nefopam shows promise as a potential therapeutic agent for cancer treatment.</p>

<p>1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea is a medicinal compound that has been used in Chinese traditional medicine for its tumor-fighting properties. It acts as a potent inhibitor of protein kinases, which are enzymes involved in cell signaling and proliferation. This analog has been shown to induce apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of specific kinases. The compound has also demonstrated anticancer activity in human cancer cell lines and may have potential as a therapeutic agent for the treatment of various types of cancer. Additionally, 1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea can be detected in urine and may serve as a biomarker for kinase inhibitor activity.</p>

<p>Desisopropyl disopyramide oxalate is a racemic mixture of the enantiomers, (+)-desisopropyl disopyramide and (-)-desisopropyl disopyramide. It is an anticholinergic drug that can be used to treat chronic depression. Desisopropyl disopyramide binds to two different sites on the enzyme p-450 and inhibits the metabolism of drugs such as benzodiazepines and tricyclic antidepressants. Desisopropyl disopyramide has been shown to have an inhibitory effect on activated muscarinic receptors in animal models, but not in humans. This drug also has anti-cholinergic effects and is used for the treatment of pediatric patients with spasticity.</p>

<p>Docetaxel Impurity D is an impurity found in the formulation of Docetaxel, a drug used to treat cancer. The impurity is a 10-deacetylated form of docetaxel that has been shown to have chiral properties. Docetaxel Impurity D can be separated from the active ingredient through chromatographic techniques and quantified by high-performance liquid chromatography. It has been found to be present in all batches of docetaxel tested, but at different concentrations.</p>

<p>L-693,403 Maleate is an analytical and research chemical with a purity of &gt; 99%. L-693,403 Maleate is used as an impurity standard for HPLC analysis and drug development. It can also be used as a reference standard in the production of APIs. L-693,403 Maleate is an impurity in the synthesis of several drugs, including clozapine, fluoxetine, and loratadine. The natural form of L-693,403 Maleate can be found in the leaves of the plant Acacia holosericea. Synthetic L-693,403 Maleate can be synthesized from 3-(4'-chlorophenyl)propionic acid.</p>

<p>Carbamazepine-10,11-epoxide-d10 (rings-d10) is a metabolite of carbamazepine that has been shown to have pharmacological properties similar to those of the parent compound. It is used in drug development, metabolism studies, and as an impurity standard for pharmaceutical products. Carbamazepine-10,11-epoxide-d10 (rings-d10) is not found in nature and can be synthesized from carbamazepine. This metabolite has a purity of at least 98% and may be used as an analytical standard or as a research and development compound for pharmacopoeia.</p>

<p>Lumiflavin-3-acetic acid is a dietary supplement that has been shown to enhance the rate of carboxylation of tryptophan by its conversion to 5-hydroxytryptophan. This compound is a flavin and can be used as an electron acceptor in techniques involving carbanion formation. Lumiflavin-3-acetic acid is not sensitive to diketones, making it an insensitive reagent for the detection of this class of compounds. It also has a constant kinetic constant and can be used as a supplement in uncatalyzed reactions due to its lack of reactivity with proton transfer. This molecule also has nuclear polarization properties, which allow it to be used in nuclear magnetic resonance (NMR) spectroscopy.</p>

<p>Aminopentamide sulfate is a pharmaceutical dosage form that is a polymeric matrix containing glycol ether, fatty acid ester, and glycol ester. It is used as a local anesthetic to numb the skin and other tissues. Aminopentamide sulfate can be administered topically or by injection into the body. It has been shown to have therapeutic effects on animals with pain-related conditions such as arthritis and neuropathy. The intramolecular hydrogen bonds in aminopentamide sulfate are thought to be formed between the carbonyl group of atropine sulfate and the hydroxyl groups of benzimidazole derivatives. These functional groups form hydrogen bonds with fatty alcohols in the matrix, which may help stabilize it.</p>

<p>2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.</p>

<p>1-Hydroxy-3-nitrodeamino fingolimod is a drug product that belongs to the class of drugs known as immunosuppressants. It is a synthetic, non-natural compound that belongs to the family of drugs known as sphingosine analogues. The HPLC standard for 1-hydroxy-3-nitrodeamino fingolimod is available and can be used in research and development or analytical studies. This drug has been shown to have niche applications in the treatment of multiple sclerosis, but it is not yet included in any pharmacopoeia.</p>

<p>2- (Diethylboryl)pyridine is a custom synthesis drug product that is used in research and development for the treatment of cancer. 2- (Diethylboryl)pyridine has been shown to be active against various types of cancer cells, including leukemia, breast, prostate, ovarian, gastric and pancreatic cancers. This compound can also be used as an impurity standard for HPLC analysis.</p>

<p>(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.</p>

<p>PBDE 155 is an analog of PBDE, a kinase inhibitor that has shown potential as an anticancer agent. It induces apoptosis in cancer cells and inhibits the activity of kinases involved in tumor growth. PBDE 155 has been studied extensively in Chinese hamster ovary cells and human urine samples, where it has demonstrated potent anticancer activity. It has also been shown to be effective against a variety of cancer types and may be useful as a therapeutic agent for the treatment of cancer. Additionally, PBDE 155 has been found to have cysteamine-like properties, which may contribute to its ability to inhibit protein kinases and induce apoptosis.</p>

<p>Fluorobexarotene is a fatty acid that has been shown to induce the expression of inflammatory genes in animal models. It has also been shown to inhibit the growth of human cancer cells in vitro and in vivo. Fluorobexarotene is used for the diagnosis of x-linked adrenoleukodystrophy and is currently being studied as a treatment for liver cancer. This molecule is also an agonist of retinoic acid receptors, which may be responsible for its effects on gene transcription.</p>

<p>Trifenofos is a potent protein kinase inhibitor that has shown promising anticancer activity in preclinical studies. It targets specific kinases involved in tumor growth and survival, leading to apoptosis or programmed cell death of cancer cells. Trifenofos is an analog of a natural toxin found in Chinese urine, which has been used for centuries in traditional medicine to treat various ailments. In addition to its anticancer properties, trifenofos also shows potential as an inhibitor of other diseases involving abnormal protein kinase activity. Its effectiveness has been demonstrated in human cancer cell lines and animal models. With its ability to selectively target cancer cells, trifenofos holds great promise as a potential therapeutic agent for the treatment of various cancers.</p>

<p>Please enquire for more information about 5-Deoxy-Δ5,6-8-epi-tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-(Propylamino)-propiotoluidid-hydrochlorid is a drug product that is used as an analytical standard for the determination of impurities in pharmaceuticals. It is a synthetic, natural, and research and development metabolite with niche applications. This product has been shown to be pharmacologically active in metabolism studies on animals. CAS No. 35891-99-7</p>

<p>Clomiphene is a drug that is used to treat female infertility. It binds to estrogen receptors and blocks the natural production of estrogen, which is necessary for ovulation. Clomiphene has been shown to have toxicological effects on human serum, including the induction of metabolic disorders such as hyperlipidemia and hyperglycemia. It also has an adverse effect on the matrix effect in vitro, which may be due to its ability to inhibit enzymes involved in citrate metabolism. Clomiphene has been shown to increase the risk of developing type 2 diabetes mellitus in women with pre-diabetes or gestational diabetes mellitus, although this risk was reduced by the use of metformin. Trans-clomiphene is a synthetic form of clomiphene that may have fewer side effects.</p>

<p>Please enquire for more information about Tyk2-in-5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluocortolone Impurity 1 is a metabolite of fluocortolone. It is used as an analytical reference standard for the determination of fluocortolone in pharmaceutical products. Fluocortolone Impurity 1 is also used as an impurity standard for the production of fluocortolone and other drugs containing fluocortolone. Fluocortolone Impurity 1 is listed in the U.S. Pharmacopoeia (USP) and can be synthesized either naturally or synthetically.</p>

<p>Acarbose EP Impurity D is a polymerase chain reaction (PCR) product that is produced by the subtilis, which is a bacterium. Acarbose EP Impurity D has been shown to inhibit the growth of viruses and bacteria in vitro. It inhibits the synthesis of bioactive molecules by inhibiting the activity of cellular enzymes, such as polymerase chain reaction products. Acarbose EP Impurity D also inhibits viral replication and has been shown to have an inhibitory effect on HIV-1 protease.</p>

<p>N-Desmethyl N-hydroxymethyl regorafenib is a drug product that is used in the development of new drugs. It is a chemical intermediate that has been synthesized to produce a desired metabolite. The molecule contains two methyl groups, two hydroxyl groups, and one carboxylic acid group on the aromatic ring. This product has been purified to high purity by analytical methods.</p>

<p>2-Fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-N,beta-diphenylbenzenebutanamide is a drug product that is an impurity from the synthesis of 2,6-dichloroquinazoline. It has been shown to have antihistaminic effects in rats. The impurity standard for this product is available for custom synthesis upon customer request.</p>

<p>Please enquire for more information about 11-Oxo-betamethasone-17-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Aztreonam Impurity 5 is a drug product that is used as an analytical standard in HPLC. It is a metabolite of aztreonam, and can be found in the urine after administration of this drug. Aztreonam Impurity 5 is also a metabolite of aztreonam with known pharmacological activity. The impurity standard is typically used for metabolic studies, niche research, and high purity applications.</p>

<p>Hydrolyzed pomalidomide M10 is an impurity standard that is used to generate the typical chromatographic profile of a drug product. It is a metabolite of pomalidomide, which is a chemotherapeutic drug used in the treatment of multiple myeloma. Hydrolyzed pomalidomide M10 has CAS number 918314-45-1 and is a natural or synthetic compound.<br>Hydrolyzed pomalidomide M10 has been shown to be an analytical standard for HPLC methods, as well as being an impurity standard for pharmacopoeia and custom synthesis. The high purity and potency of this compound make it ideal for drug development, research and analysis.</p>

<p>Ceftazidime impurity H is a by-product that can be found in the synthesis of ceftazidime. It has been detected using magnetic separation and UV detection. Ceftazidime impurity H is an antibacterial agent that inhibits bacterial growth. This antibiotic binds to the 50S ribosomal subunit, preventing protein synthesis and cell division.</p>

<p>(betaR,deltaR)-2,3-Bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt is an impurity that is used in the production of a drug product. This product is metabolized to (betaR,deltaR)-2,3-bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole 1 heptanoic acid which is used as an analytical standard for HPLC.</p>

<p>Sacubitril Impurity 19 is a drug product that is used as an analytical standard for the purity and concentration of sacubitril. It is also used as an impurity in API manufacture. Sacubitril Impurity 19 is a natural metabolite of sacubitril, which is synthesized from the chemical reaction between sacubitril and hydroxypropyl-beta-cyclodextrin. The impurity has been shown to be eliminated through metabolism studies in rats. Sacubitril Impurity 19 can be found at a concentration of up to 0.2% in commercial samples of sacubitril. It may be present at levels up to 10% in medicinal products containing sacubitril.</p>

Please enquire for more information about Bis N-benzyloxycarbonyl-6-o-benzyl-valacyclovir including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Phenproxide is an analog of testosterone that has been used traditionally in Chinese medicine to treat tumors. It has been found to induce apoptosis in cancer cells by inhibiting kinases, which are enzymes that regulate cellular processes such as cell division and growth. Phenproxide has also been shown to inhibit the activity of somatostatin, a hormone that regulates the release of other hormones. This inhibition may contribute to its anti-cancer properties. In addition, Phenproxide has been shown to have an effect on hyaluronan metabolism, a substance involved in tissue repair and inflammation. It is excreted in urine and may be used as a potential biomarker for cancer diagnosis or monitoring.</p>

<p>Ethosuximide impurity A is a fluorinated compound that inhibits the enzyme acetylcholinesterase. It has been shown to inhibit the catalytic mechanism of acetylcholinesterase, which leads to its inhibitory effect on the enzyme. The compound does not have any structural similarity to the other known inhibitors of this enzyme. Ethosuximide impurity A has been shown to be an antimutagen and anticarcinogen in vitro, with a postulated mechanism of action that involves inhibition of a water molecule from binding to the active site.</p>

<p>2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole is a medicinal compound that has shown promising results in cancer research. It works as an inhibitor of cyclin-dependent kinases, which are essential for cancer cell proliferation. This compound induces apoptosis in cancer cells by inhibiting the activity of certain proteins involved in tumor growth. Studies have shown that 2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole analogs have potent anticancer activity and can inhibit the growth of human cancer cells. This compound has also been found to be present in urine samples from Chinese patients with cancer. Further research on this compound may lead to the development of new and effective treatments for various types of cancers.</p>

<p>RS 39604 hydrochloride is a mitochondrial function inhibitor that blocks the uptake of mitochondrial substrates, thereby inhibiting the synthesis of ATP. RS 39604 hydrochloride is also an inhibitor of 5-HT1A receptors, which are found in the striatal membranes and play a role in regulating dopamine release. These properties make RS 39604 hydrochloride a potential therapeutic agent for conditions such as Parkinson's disease and cardiac arrhythmia.</p>

<p>Adiporon hydrochloride is an API impurity, which is a natural product that has been used in traditional Chinese medicine to treat obesity. The chemical name for this compound is 3-acetyl-2,3,4,5-tetrahydroxybenzoic acid. Adiporon hydrochloride has shown weight loss effects in mice and rats. It is metabolized by the liver and excreted by the kidneys. Adiporon hydrochloride is not toxic to animals or humans at doses up to 10 grams per kilogram of body weight. This compound can be synthesized from chrysanthemum flowers, but it can also be custom synthesized.</p>

<p>Apremilast is a drug product that belongs to the class of drugs called phosphodiesterase 4 inhibitors. It acts by inhibiting the enzyme phosphodiesterase 4 (PDE4) and therefore blocks the degradation of specific signaling molecules, such as cyclic adenosine monophosphate (cAMP). Apremilast has been shown to have anti-inflammatory properties in preclinical studies and is being developed for the treatment of inflammatory diseases, including rheumatoid arthritis. Apremilast is not active against gram-positive bacteria or some other types of bacteria. Apremilast has been shown to have a low potential for drug interactions with other drugs metabolized by cytochrome P450 enzymes.</p>

<p>Please enquire for more information about 1,4-Dihydro-4-oxo-3-quinolinecarbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>