APIs per la ricerca e le impurità

Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.

Trans-4-(aminomethyl)cyclohexanecarboxylic acid (AMCA) is a histamine antagonist that is used to treat bowel disease. It may also be useful for the treatment of other inflammatory diseases and as an anticoagulant. AMCA has been shown to be safe and effective for the prevention of postoperative bleeding in patients who are undergoing major surgery. This drug is a potent inhibitor of platelet aggregation, but does not affect the function of erythrocytes or leukocytes. AMCA inhibits platelet aggregation by blocking the binding of adenosine diphosphate (ADP) to its receptor on platelets, thus inhibiting ADP-mediated activation of phospholipase A2 and arachidonic acid release from membranes. An increase in blood levels of AMCA may lead to cardiac toxicity and bleeding events.

2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] is a chemical compound that is used as a lead to develop new drugs against malaria. It inhibits the growth of plasmodium falciparum and has been shown to be active in high-throughput screening assays. 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] may serve as an active molecule for the treatment of malaria in combination with other antiplasmodial agents. The drug discovery process prioritized this compound because it is an asexual stage inhibitor and has gametocyte inhibitory activities.

Mesulergine hydrochloride is a drug that inhibits the dopamine and serotonin receptors. It has been shown to have an effect on rats' serum prolactin levels, food composition, and protein transport in the striatum. Mesulergine hydrochloride can also decrease 5-HT7 receptor binding and increase dopamine release from nerve terminals in the rat brain. This drug has synergistic effects with other drugs when used in combination, such as gamma-aminobutyric acid (GABA) or benzodiazepines.
Symptoms of mesulergine hydrochloride include psychotic disorders, anxiety, depression, hallucinations, sleep problems, and suicidal thoughts. These symptoms may be due to mesulergine's effect on 5-HT2C receptors.

L-Valine 2-hydroxyethyl ester tosylate (L-V2HT) is a drug product that is synthesized by custom synthesis. It has high purity, analytical, and natural properties. L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The active form of L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. L-V2HT also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell

Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.

Methyl 2-sulfinobenzoate (MSB) is an analytical, research and development, and drug development impurity that is used as an API impurity and HPLC standard. It is a metabolite of sulfadiazine, which belongs to the family of drugs known as sulfonamides. MSB has been shown to have pharmacopoeia activity for the treatment of bacterial infections. It is a natural product found in plants, such as garlic and onion, or it can be synthesized from benzene and sulfur chloride.

Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate is an analytical standard used to identify impurities in drug products. It is a metabolite of the drug product and has been shown to be safe for human consumption. The compound is a synthetic chemical that is not found naturally in the environment. CAS No. 180468-42-2

Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.

2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].

Tetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.

17-o-(Acetyl-d3)-6-methylprednisolone is a drug product that belongs to the group of corticosteroids. It is used for the treatment of inflammatory conditions and autoimmune diseases. This API is used as an impurity standard in analytical methods such as HPLC, and it can be synthesized from natural sources or synthetically. 17-o-(Acetyl-d3)-6-methylprednisolone can also be used in R&D for the development of drugs targeting niche markets, such as those with high purity requirements.

Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.

7-O-methyl ivermectin is a drug product that is an analytical standard for the impurity 7-O-methyl ivermectin B1a. Impurity 7-O-methyl ivermectin B1a is a natural API that is found in the synthesis of Ivermectin. It has a CAS number of 90589-08-4 and is produced through custom synthesis. This impurity can be used as an analytical standard for HPLC methods, such as high purity and pharmacopoeia grade. 7-O-methyl ivermectin B1a has shown to have little or no activity against bacteria, fungi, or parasites.

Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.

2-Amino-N-(2-benzoyl-4-chlorophenyl)-N-methylacetamide is an impurity in the drug product, which is a metabolite of the active drug. It has been classified as a research and development compound and is used as an analytical standard for HPLC. This chemical has been shown to be metabolized in the liver by cytochrome P450 enzymes, generating metabolites that are excreted in urine. 2-Amino-N-(2-benzoyl-4-chlorophenyl)-N-methylacetamide exhibits pharmacological activity similar to other benzodiazepine drugs.

Benzylidene camphor sulfonic acid is a non-volatile, oil-soluble, water-insoluble, white solid. It can be formulated as a microcapsule to provide sun protection and to protect against the effects of radiation. Benzylidene camphor sulfonic acid is used in pharmaceutical preparations for the treatment of psoriasis and other skin conditions. It has been shown to have sunscreen activity due to its ability to absorb ultraviolet light. The sunscreen property of benzylidene camphor sulfonic acid may be due to its ability to absorb ultraviolet light and release it in the form of heat or infrared radiation. Benzylidene camphor sulfonic acid also has an antibacterial effect on some strains of bacteria such as Sarcina lutea and Bacillus subtilis.

Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.

[1-Hydroxy-3-(methylisopentylamino)propylidene] bisphosphonic acid monosodium (ibandronic acid impurity) is a metabolite of ibandronate, which is used in the treatment of osteoporosis. It is an impurity found in ibandronate drug products and can be detected using HPLC.

Tiotropium EP Impurity I is an impurity found in the API, Tiotropium EP. It is a natural product that is synthesized by chemical synthesis. The synthetic purity of Tiotropium EP Impurity I is high and complies with pharmacopoeia guidelines. This impurity can be used as a standard to test the quality of other products or to research the metabolism of Tiotropium EP.

Risperidone carboxylate impurity is an analytical reference standard of risperidone that is used in the research and development, drug development, and production of drugs. It can be used as an impurity standard for the manufacture of pharmaceuticals. Risperidone carboxylate impurity has a molecular weight of 514.83 g/mol and a melting point of 200-202°C. Its CAS number is 1346603-86-8. Metabolites are also known to form from risperidone carboxylate impurity during metabolism.

Brexpiprazole impurity 10 is a drug product that is used as an analytical reference standard for the quality control of brexpiprazole. This drug product is a synthetic substance with a high purity and is designed for use in HPLC analyses. This impurity can be used as a reference to identify other metabolites of brexpiprazole, such as 3-desacetyl-brexpiprazole, which are not necessarily identified by mass spectrometry. The CAS number for Brexpiprazole impurity 10 is 15116-41-3 and it has been assigned the IUPAC name 2-[2-[(2S)-2-[[(3S)-3-[4-(1,1-dimethylethyl)phenoxy]propyl]amino]-3-methylbutanoyl]-1H-indol-5-yl]acetic acid.

Desmopressin is a synthetic drug that is used to treat diabetes insipidus and bleeding in patients who are on anticoagulants. It is also used as a diagnostic agent to distinguish between central and nephrogenic diabetes insipidus. Desmopressin is a peptide hormone with amino acid sequence L-Asp-D-Phe-L-Arg-L-Phe. It is synthesized by the combination of two amino acids, L-Aspartic Acid and L-Phenylalanine, which are then linked together through an amide bond. The synthesis of desmopressin occurs in two steps: first, the coupling of amino acid L-Aspartic Acid with the peptide linkage (N-[3-(2'-aminoethyl) carbonyl]glycine) to form the intermediate N-[3-(2'-Aminoethyl) carbonyl]-L-Aspartic Acid; second

Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine is a drug product with a CAS number of 70406-92-7. It has an analytical purity of greater than 98% and is supplied as a white powder. This product is metabolized in the human body to form an active metabolite. The chemical name for this drug product is ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine, which can be found in the pharmacopoeia under the name of 6′ amino 2,3′ dichlorobenzyl glycine.

N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is a synthetic compound that has not been identified in nature. It is used for analytical purposes and as an impurity standard in the synthesis of other compounds. N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is the parent drug product of CAS No. 896736–22–4. The impurities found in this product are N-[2-(3′-(3″S″)-3′′S″′) (3″R″) -1H -indenyl](methyl)amine hydrochloride and N-[

Vandetanib N-oxide is a drug product that is custom synthesized for research and development purposes. It has been shown to have high purity, analytical, and natural properties. Vandetanib N-oxide can be used as a metabolite or impurity standard in pharmacopoeias, such as the USP. The compound also has niche use in drug development and metabolism studies.

(S,S)-IsoValganciclovir hydrochloride is a drug product with a purity of 99.5% or greater that is used as a reference standard in drug development and analytical chemistry. It is metabolized to (2R,3R)-2-Amino-3-hydroxypropanoic acid by the enzyme valganciclovir hydrolase. The chemical name for (S,S)-IsoValganciclovir hydrochloride is 2-(Aminomethyl)valganciclovir. The CAS registry number for this compound is 1401562-13-7.

6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate is a synthetic compound that is used as an analytical reference standard for the metabolism studies. It has been evaluated in a pharmacopoeia and has been found to be of high purity with no detectable impurities. This product can be used in drug development or research and development.

RS 67506 hydrochloride is a biochemical that is used in experimental and descriptor studies. The ketone group has been found to be an important part of the molecular structure. RS 67506 hydrochloride has been shown to have a number of biological properties, including inhibition of the synthesis of neurotransmitters such as dopamine, serotonin and norepinephrine; it also has anti-nervous system activity. This chemical was also found to inhibit the synthesis of prostaglandin E2 in human neutrophils. It is hypothesized that RS 67506 hydrochloride may inhibit phospholipase A2, which would prevent the release of arachidonic acid from phospholipids into the cell membrane and block the production of eicosanoids.

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.

Imipramine N-oxide hydrate is a drug product that is used in the synthesis of other drugs. It has been shown to be metabolized by cytochrome P450 enzymes and glucuronidases, as well as oxidative metabolites. Imipramine N-oxide hydrate is a metabolite of imipramine.

CPI 0610 is a medicinal compound that acts as a potent inhibitor of protein phosphorylation. It has been shown to inhibit the cell cycle and promote apoptosis in Chinese hamster ovary cells. CPI 0610 is an effective inhibitor of kinase activity in cancer cells, leading to decreased tumor growth and increased survival rates. In preclinical studies, CPI 0610 has demonstrated efficacy against a wide range of cancers, including breast, prostate, and lung cancer. This inhibitor has also been shown to be effective in human cancer cell lines, making it a promising candidate for future cancer therapies.

Quinidine is a drug that has been used in the treatment of cardiac arrhythmias and as an antiarrhythmic. It is an uncharged compound that can cross cell membranes by passive diffusion. Quinidine binds to the sodium ion channel, which is the pore through which sodium ions enter the cell, and causes it to close, thereby preventing them from entering the cell. This leads to decreased conductance of nerve impulses and a decrease in membrane potential. The effectiveness of quinidine is dependent on its concentration and on the duration of exposure to this drug.

N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit

Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material or a pharmacopoeia for HPLC standards.
Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material

(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt is a synthetic drug product. It is an impurity standard in the synthesis of Metabolism studies. The CAS number is 1714147-50-8 and the chemical name is (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2 methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5dihydroxyheptenoic acid sodium salt. The molecular weight is 781

Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0

4-[2-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium Chloride Monohydrochloride is a drug product under development for the treatment of bacterial infections. 4-[2-[(6R,7R)-7Amino--2carboxy8oxo5thia1azabicyclo[4.2.0]oct2en3yl]thio]-4thiazolyl]-1methylpyridinium Chloride Monohydrochloride is an impurity in the API Methicillin (CAS No. 40082764). Impurities are not necessarily undesirable and may have substantial therapeutic value or provide a desired

(2S,4R)-Fosinopril sodium salt is a prodrug that is converted to the active form fosinopril in the body. It is used to treat high blood pressure and heart failure. Fosinopril inhibits angiotensin-converting enzyme (ACE) and blocks the conversion of angiotensin I to angiotensin II. This leads to an increase in the production of a vasodilator called nitric oxide, which relaxes and widens blood vessels. Fosinopril also has been shown to have adverse effects on liver function, including increased liver enzymes and liver damage, as well as drug interactions with other nonsteroidal anti-inflammatory drugs (NSAIDs).

2-(4-Formylphenyl)propionic acid is a racemic mixture of 2-formylphenylacetic acid and 4-formylphenylacetic acid. This compound is used in the treatment of bacterial infections and inflammation. It is an organic solution that can be injected, administered orally, or applied topically. The 2-(4-formylphenyl)propionic acid has been shown to have anti-inflammatory properties, but also has side effects such as skin irritation when it is applied topically. This drug can also cause nausea, vomiting, and diarrhea when administered orally.

Irinotecan is a drug product that is used in the treatment of cancer. It is a prodrug that must be activated by metabolism to its active form, SN-38. Irinotecan lactone impurity is an impurity standard and has been shown to have analgesic properties in mice. It has also been shown to inhibit the growth of colon cancer cells.

(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.

1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.

Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.

(S)-3-((R)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a drug product of the drug development industry. It is a metabolite of 3-(1,2,4-triazol-1-ylmethyl)thiazolidine-4-carboxylic acid and has been used as an analytical standard for HPLC methods. The compound has been shown to be naturally occurring in humans. (S)-3-(1,2,4-Triazol-1ylmethyl)thiazolidine 4 carboxylic acid is also used as the impurity standard for the API 3-(1,2,4 triazol 1ylmethyl)thiazolidine 4 carboxylic acid.

Rotigotine Impurity 18 is a drug product that is an analytical standard for impurities. It is a synthetic impurity that is not found in natural sources. Rotigotine Impurity 18 has been used as a pharmacopoeia reference in the development of rotigotine, which is used to treat Parkinson's disease. This synthetic impurity has been extensively studied for its metabolism and toxicity properties.

2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene is an impurity found in sulfasalazine. It is a metabolite that is formed by the P450 system in the liver. The metabolic process of 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene has been studied in detail and has been shown to be a major contributor to the pharmacokinetic profile of sulfasalazine. This substance also exhibits antimicrobial activity and inhibits the growth of bacteria, fungi, and viruses.

Quetiapine is a drug that belongs to the class of sulfoxides. It is usually administered orally, but can also be given intravenously or intramuscularly. Quetiapine has been studied for its clinical use in the treatment of schizophrenia and bipolar disorder. The plasma concentrations of quetiapine are determined by high-performance liquid chromatography (HPLC) with tandem mass spectrometry (LC-MS/MS) detection. Validation studies have shown that the HPLC-MS/MS method is accurate and precise, with good linearity over a range of concentrations. Analysis was performed on plasma samples from healthy volunteers who were administered either 2 mg or 10 mg doses of quetiapine by intravenous injection. Concentrations were calculated and compared to those found in patients with schizophrenia and bipolar disorder who had been given oral doses of 300 mg per day for four weeks, yielding a therapeutic plasma concentration range from 100 to 300 ng/mL.

Pirtenidine is a potent and selective kinase inhibitor that has been shown to inhibit the activity of cyclin-dependent kinases. It has demonstrated promising results in preclinical studies as an anticancer agent, inducing apoptosis in cancer cells. Pirtenidine is an analog of protein kinase inhibitors, which have been used to treat various types of tumors. It has been found to be effective against human cancer cell lines and has shown significant tumor growth inhibition in animal models. Pirtenidine has also been reported to be a potent urine inhibitor of Chinese hamster ovary cells, making it a promising candidate for the treatment of urinary tract cancers.

Methyl mycophenolate impurity E is a reactive, propargylamine-containing, monosodium salt with immunosuppressive properties. It is used in the treatment of cancer by inhibiting the production of white blood cells, which are needed to fight infection. Methyl mycophenolate impurity E has shown antitumor activity and can be used for the treatment of some types of cancer. It is metabolized in vivo to methyl mycophenolate and inhibits protein synthesis by alkylating DNA.

4-Methanesulfonyloxybutanol is a chemical substance with the molecular formula CH3SO2CH(CH2OH)CH2OH. It is used as an intermediate in the synthesis of 4-methanesulfonyloxybutanol, which is a potent inhibitor of busulfan-induced leukopenia and myelosuppression. This substance has been shown to be highly effective in preventing busulfan-induced side effects when administered intravenously. 4-Methanesulfonyloxybutanol is chemically synthesized by intramolecular alkylation of butanol, followed by hydrolysis. The reaction product can be detected using an ionization detector in conjunction with gas chromatography. This product is an alkylation agent that reacts with polypropylene to produce polypropylene glycols.

Valsartan is a drug that belongs to the class of angiotensin II receptor blockers. It has a molecular weight of 376.5 and an empirical formula of C21H28N2O4S. Valsartan Impurity 23 is a synthetic impurity with CAS No. 2459446-44-5, which has a molecular weight of 464.3 and an empirical formula of C25H30N2O6S. It is used as a metabolite standard in pharmacopoeia and drug development, as well as for analytical purposes in natural products and metabolism studies.

Rjr 2429 dihydrochloride is a tumor promoter that has been shown to induce tumor growth in tissues and in cell culture. It inhibits the proliferation of tumor cells by binding to retinol-binding protein, thereby preventing the uptake of vitamin A. Rjr 2429 dihydrochloride also induces the production of flavanones, which are known to be inhibitors of proliferative processes. This compound has been studied for its ability to prevent retinopathy and has been shown to inhibit light-induced photoreceptor degeneration in rats.

Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.

Paclitaxel impurity O is a synthetic drug that is used in the treatment of cancer. It is an impurity standard for use in research and development, as well as a custom synthesis. Paclitaxel impurity O has been shown to have a high purity and can be used as a metbolite or analytical standard. It has been shown to possess anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

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Roxithromycin is a macrolide antibiotic that inhibits protein synthesis in bacteria. It binds to the 50S ribosomal subunit, thereby inhibiting bacterial growth. Roxithromycin has been used to diagnose intestinal and esophageal diseases, inflammatory diseases, and cancer. There are some cardiac effects associated with Roxithromycin that may be related to its ability to inhibit serotonin reuptake. This drug also has anti-inflammatory properties and has been shown to be effective against influenza virus infections as well as other infectious diseases such as tuberculosis and HIV/AIDS.

Boc-3-hydroxy-1-adamantyl-glycine is a catalytic, nucleophilic, chiral amino acid that is used in the synthesis of oximes. Boc-3-hydroxy-1-adamantyl-glycine has been shown to be an effective substitute for hydroxylamine in reductive amination reactions and can be used to synthesize some pharmaceuticals, including saxagliptin. This compound is stable under standard conditions and can be easily synthesized. It is also a powerful nucleophile that reacts with electrophiles such as chloroformates and sulfonyl chlorides.

Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.

N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.

Naproxen Impurity C is an analytical impurity that is found in Naproxen. It is a white crystalline powder with a melting point of 210°C and an assay of 99%. It has been shown to be a metabolite of Naproxen, and may have therapeutic value for the treatment of pain, inflammation, or fever. The purity of this product has been verified by HPLC analysis.

Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.

Linagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.

Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.

(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

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N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.

Etofenamate impurity

Semaglutide impurity.

Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>

Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis.  Made to order.