APIs per la ricerca e le impurità
I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.
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3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid
CAS:3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid is a potent protein kinase inhibitor with anticancer properties. It is an analog of emodin, a natural compound found in Chinese medicinal herbs. This compound has been shown to inhibit the growth of cancer cells and induce apoptosis through the inhibition of various kinases. Its potential as an anticancer drug has been demonstrated in vitro and in vivo studies, where it has shown to reduce tumor size and metastasis. This compound has also been detected in human urine, suggesting that it may have potential as a diagnostic marker for cancer. The discovery of 3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid may lead to the development of new inhibitors for various kinases and improve cancer treatment options.Formula:C16H10O6Purezza:Min. 95%Peso molecolare:298.25 g/molMethyl 2-deoxy-D-ribopyranoside
CAS:Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.Formula:C6H12O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:148.16 g/molClarithromycin EP Impurity A
CAS:Clarithromycin EP Impurity A is an analytical standard for clarithromycin. Clarithromycin EP Impurity A is a white to off-white powder that is soluble in methanol, acetone, and chloroform. It has a molecular weight of 459.23 Da and the chemical formula C18H26N2O5S. Clarithromycin EP Impurity A is an impurity found in clarithromycin that has been isolated from the product by high-performance liquid chromatography (HPLC) and confirmed by nuclear magnetic resonance spectroscopy (NMR). Clarithromycin EP Impurity A can be used as a reference standard for pharmacopoeia testing or as a research and development sample for drug development. It can also be synthesized from natural or synthetic sources.
Formula:C38H69NO14Purezza:90%NmrColore e forma:PowderPeso molecolare:763.95 g/molCinacalcet Impurity B HCl
CAS:Cinacalcet Impurity B HCl is an analytical standard that can be used in HPLC as a reference compound. It is also a metabolite of Cinacalcet and has been shown to have affinity for calcium channels. This impurity is found in Cinacalcet at a concentration of less than 1%.Formula:C19H20NClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:297.82 g/mol5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
CAS:5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.
Formula:C17H15NO3Purezza:Min. 95%Peso molecolare:281.31 g/mol(R,R)-Montelukast bis-sulfide
CAS:(R,R)-Montelukast bis-sulfide is a drug product that is used in the analytical and research and development of drugs. It is also used as an impurity standard for HPLC. (R,R)-Montelukast bis-sulfide has been shown to have niche applications in drug development and research, as well as being a high purity API.Formula:C41H46ClNO5S2Purezza:90%MinPeso molecolare:732.39 g/molDescarboxyl febuxostat
CAS:Descarboxyl febuxostat is a synthetic drug that is metabolized to its active form, febuxostat. This drug product has been custom synthesized and is of high purity. Descarboxyl febuxostat has been used in the development of drugs for hypertension, hypercholesterolemia, and gout. It has also been used as a research tool for studying the metabolism of drugs in humans.Formula:C15H16N2OSPurezza:Min. 95%Peso molecolare:272.40 g/molSumatriptan EP Impurity A
CAS:Sumatriptan EP Impurity A is a metabolite of sumatriptan, a drug product that is used for the treatment of migraine headaches. Sumatriptan EP Impurity A is a natural metabolite of sumatriptan and has been found to be an analytical impurity in the drug product. It has been shown to have anti-inflammatory properties and may be useful for treating arthritis. This impurity can also be synthesized by chemical synthesis or recombinant DNA technology.Formula:C27H37N5O2SPurezza:Min. 95%Peso molecolare:495.68 g/mol(R)-Sitagliptin rac-fumarate adduct
CAS:(R)-Sitagliptin rac-fumarate adduct is an analytical reference material and impurity standard. It is a natural product that is synthesized using a custom synthesis with analytical data available. The impurities of the synthetic process are well defined, with the exception of (1) an unknown peak at retention time 9.7 min and (2) a peak at retention time 12.5 min that may be due to the presence of fumaric acid or its derivatives. This product can be used for drug development research and development, as well as for establishing HPLC standards for pharmacopoeia testing.Formula:C20H19F6N5O5Purezza:Min. 95%Peso molecolare:523.40 g/mol6-Oxo simvastatin
CAS:6-Oxo simvastatin is a homolog of the cholesterol synthesis inhibitor simvastatin. It inhibits the enzyme HMG-CoA reductase, which is involved in the production of cholesterol. 6-Oxo simvastatin can be extracted from microbial cultures and has been shown to inhibit microbial transformation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) into mevalonic acid during growth. 6-Oxo simvastatin has been shown to have potent inhibitory effects on HMG CoA reductase in subspecies that are resistant to other inhibitors such as lovastatin and pravastatin.Formula:C25H36O6Purezza:Min. 95%Peso molecolare:432.5 g/molN-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic acid
CAS:N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-gamma-glutamyl-L-glutamic acid is used as a research and development purity standard. It is a white crystalline powder that is soluble in water and ethanol. N-[4-[2-(2Amino 4,7dihydro 4oxo 3Hpyrrolo 2,3d]pyrimidin 5yl)ethyl]benzoyl]-L gamma glutamyl L glutamic acid has CAS number 144051 68 3. The drug product is a synthetic compound with high purity. It has been shown to be an analytical reference substance for HPLC standards and to have niche applications in metabolism studies of other drugs.
Formula:C25H28N6O9Purezza:Min. 95%Peso molecolare:556.52 g/molMycophenolate mofetil EP impurity B oxalate
CAS:Please enquire for more information about Mycophenolate mofetil EP impurity B oxalate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C29H42N2O9•C2H2O4Purezza:Min. 95%Peso molecolare:652.68 g/molNaltrexone impurity H
CAS:Prodotto controllatoNaltrexone impurity H is an analytical standard for the detection of naltrexone in drug products. This compound is a metabolite of naltrexone and has been found to have a purity level of >98.5% by HPLC. Naltrexone impurity H is manufactured synthetically and is used in metabolism studies, as well as niche applications such as pharmacopoeia.Formula:C20H25NO4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:343.42 g/molIvermectin EP Impurity J
Ivermectin EP Impurity J is a custom synthesis that has been designed for pharmacological research and development. It is a highly pure, synthetic compound that can be used as a drug product or in the synthesis of other drugs. Impurity J is not found in nature, but can be synthesized from natural materials. Ivermectin EP Impurity J is a metabolite of ivermectin, which is produced by the metabolism of avermectins. The impurity standard for this compound is set by the pharmacopoeia and it must comply with analytical standards to ensure purity.Purezza:Min. 95%Quetiapine hemifumarate
CAS:Prodotto controllatoQuetiapine hemifumarate is an antipsychotic drug that blocks receptors for dopamine, serotonin, and adrenergic neurotransmitters. It is used to treat schizophrenia and other disorders such as bipolar disorder. Quetiapine has been shown to be effective in clinical trials. The fumarate salt of quetiapine is the form of the drug that is used in these trials. Serum prolactin levels were found to be significantly lower in patients who received the fumarate salt than those who received a placebo. Quetiapine hemifumarate may potentiate the effects of other drugs by inducing their metabolism via CYP3A4 or CYP2D6 enzymes, which are also responsible for its own metabolism. This drug can interact with other drugs such as risperidone, olanzapine, and clozapine due to its atypical nature. Quetiapine hemifumarate has side effectsFormula:C21H25N3O2S•(C4H4O4)0Purezza:Min. 95%Colore e forma:PowderPeso molecolare:441.54 g/molPitavastatin N-oxide
CAS:Pitavastatin N-oxide is a drug product that is an analytical standard and natural API impurity. It is used in the synthesis of other drugs, such as pitavastatin, which is a statin drug used to lower cholesterol levels. Pitavastatin N-oxide has been shown to be a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate. This inhibits cholesterol production and lowers levels of low density lipoprotein (LDL) cholesterol in the blood.Formula:C25H24FNO5Purezza:Min. 95%Peso molecolare:437.46 g/molMitoxantrone (2-hydroxyethyl)piperazine impurity
CAS:Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.Formula:C22H26N4O6Purezza:Min. 95%Colore e forma:Brown PowderPeso molecolare:442.47 g/molVortioxetine Impurity 19
CAS:3-Indoxyl β-D-galactopyranoside, 6-fluoro-3-indoxyl β-D-galactopyranoside, Tilmicosin, 3-Desacetylcefotaxime potassium, Gatifloxacin, Vortioxetine Impurity 19Formula:C18H22N2OSPurezza:Min. 95%Peso molecolare:314.4 g/molMethylnaltrexone Peak Identification Mixture CII (Methylnaltrexone Bromide containing about 0.1% methylnaltrexone related compound A)
Prodotto controllatoDiagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiColore e forma:White SolidAtorvastatin Cyclic Sodium Salt (Isopropyl) Impurity
CAS:Atorvastatin is a drug product with an impurity of atorvastatin cyclic sodium salt (isopropyl). The synthesis of this compound can be found in the natural and synthetic routes. Impurity standard is used to identify impurities in drugs and is necessary for pharmacopoeia, research and development, and analytical work. This compound has been shown to have high purity, analytical, metabolism studies, natural, drug development, and pharmacopoeia. CAS No. 1316291-19-6 is the impurity standard for this compound.
Formula:C33H34FN2NaO7Purezza:Min. 95%Colore e forma:PowderPeso molecolare:612.62 g/molEmtricitabine carboxylic acid
CAS:Emtricitabine (FTC) is a synthetic nucleoside analog that is approved for the treatment of HIV infection. FTC is metabolized in the liver by cytochrome P450 enzymes into two metabolites, EMTR-diol and EMTR-triol. The pharmacopoeia defines impurity standards for both metabolites. FTC also causes metabolism studies to be conducted to determine its effect on other drugs such as cyclosporin and phenytoin. EMTR-diol: CAS No. 1238210-10-0 EMTR-triol: CAS No. 1238210-11-1Formula:C8H8FN3O4SPurezza:Min. 95%Peso molecolare:261.23 g/molPimozide N-oxide
CAS:Pimozide N-oxide is a drug product that can be custom synthesized. It is a high purity, analytical standard that is metabolized by the liver to produce pimozide. Pimozide N-oxide is a metabolite of pimozide and has been used in pharmacopoeia to determine the purity of pimozide. The compound has also been extensively studied for use in drug development, as well as research and development. Pimozide N-oxide is not an impurity standard and is not a research or HPLC standard.Formula:C28H29F2N3O2Purezza:Min. 95%Peso molecolare:477.50 g/mol(3R,4S)-Tofacitinib
CAS:(3R,4S)-Tofacitinib is a synthetic compound that is being researched for the treatment of rheumatoid arthritis. It is a potent inhibitor of Janus Kinase 3 (JAK3) and Janus Kinase 1 (JAK1), which are important enzymes in cytokine signaling pathways that play a role in inflammation. (3R,4S)-Tofacitinib is metabolized to an impurity standard for the drug product. The metabolite has not been characterized and its concentration cannot be determined from analytical data.Formula:C16H20N6OPurezza:Min. 95%Peso molecolare:312.37 g/molMelphalan dimer
CAS:Melphalan dimer is an anticancer drug that belongs to the class of kinase inhibitors. It works by inhibiting kinases, which are enzymes that play a critical role in cancer cell growth and survival. This medicinal compound has been shown to induce apoptosis or programmed cell death in human cancer cells. The analog of melphalan dimer has also been found in urine protein, indicating its potential as a biomarker for cancer diagnosis and treatment. Melphalan dimer is effective against various types of tumors, including Chinese hamster ovary cells and human melanoma cells. Its potent anticancer activity makes it a promising candidate for cancer therapy.Formula:C26H35Cl3N4O4Purezza:Min. 95%Peso molecolare:573.9 g/molVildagliptin related compound F
CAS:Vildagliptin related compound F (VRCF) is a drug product that has been custom synthesized. VRCF is a high purity, analytical standard. It is metabolized in the body and can be used as a research and development standard to study the metabolism of vildagliptin. VRCF is a natural metabolite that has been identified as an impurity in the drug product Vildagliptin. VRCF has not been recognized by the USP or EP for use as an impurity standard. CAS no: 1789703-36-1Formula:C17H24N2O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:304.4 g/molEzetimibe ketone
CAS:Ezetimibe ketone is a lipid-lowering agent that inhibits cholesterol absorption through the inhibition of Niemann-Pick C1-like 1 (NPC1L1). Ezetimibe ketone is used to reduce the levels of low-density lipoprotein cholesterol (LDL-C) in patients with primary hypercholesterolemia, sitosterolemia, and familial combined hyperlipidemia. Ezetimibe ketone has been shown to be bioequivalent to ezetimibe, which is an oral drug that inhibits cholesterol absorption by blocking NPC1L1. The drug binds to the NPC1L1 receptor in the brush border membrane of enterocytes and prevents cholesterol uptake. Ezetimibe ketone has a high solubility in organic solvents such as dichloromethane or chloroform. It also has a high melting point, which makes it suitable for use on chromatographic columns.Formula:C24H19F2NO3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:407.41 g/molDiflorasone 17-propionate
CAS:Diflorasone 17-propionate is a synthetic corticosteroid with the chemical name of 9,11-difluoro-17-hydroxy-16-methylpregna-1,4,9(11)-trienoic acid 17-propionate. It is an impurity standard in the manufacture of diflucortolone acetate. Diflorasone 17-propionate is used in drug development and analytical studies for its high purity and pharmacopoeia quality. Its metabolite profile has been investigated using HPLC with UV detection. Metabolism studies have been conducted to determine the metabolic pathway of diflorasone 17-propionate in humans.Formula:C25H32F2O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:466.5 g/mol1-Oxo mirtazapine
CAS:1-Oxo mirtazapine is a metabolite of mirtazapine. It is a synthetic compound and is not found in nature. This product is a research and development impurity standard for the preparation of drug product, which has been synthesized to be highly pure. The material is used for drug development, including pharmacopoeia requirements for analytical studies and metabolism studies. 1-Oxo mirtazapine has been shown to have niche applications in pharmacopoeia and as an HPLC standard.
Formula:C17H17N3OPurezza:Min. 95%Peso molecolare:279.34 g/mol7-Epi 10-desacetyl paclitaxel
CAS:7-Epi 10-desacetyl paclitaxel is a prodrug of paclitaxel. It has a similar mechanism of action to paclitaxel, and is used as a chemotherapeutic agent for the treatment of cancer. 7-Epi 10-desacetyl paclitaxel has shown potent apoptotic activity in cell culture, as well as in animal models. This drug is prepared by high performance liquid chromatography and is used to treat cancer. The drug may also be activated by an enzyme called adenosine diphosphate ribose (ADPR), which forms from ATP during cellular metabolism. 7-Epi 10-desacetyl paclitaxel may also have anticancer effects on cervical cancer cells due to its ability to inhibit the synthesis of DNA and RNA.Formula:C45H49NO13Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:811.87 g/molSimvastatin dimer impurity
CAS:Simvastatin is a statin that reduces cholesterol synthesis by inhibiting the enzyme HMG-CoA reductase. Simvastatin is an amide, which is a derivative of the drug substance with a chloride group. It is commonly used in pharmaceutical formulations as an impurity in the synthesis of simvastatin. The presence of this impurity can be detected using chromatographic techniques, such as liquid chromatography and gas chromatography.
Formula:C50H76O10Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:837.13 g/molCalcipotriol EP impurity B
CAS:Please enquire for more information about Calcipotriol EP impurity B including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C27H40O3Peso molecolare:412.61 g/mol1-Bromo-3,5-dimethyladamantane
CAS:Intermediate in the synthesis of memantineFormula:C12H19BrPurezza:Min. 95%Peso molecolare:243.18 g/mol4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(trityltetrazol-5-yl)phenyl]phenyl]methylimidazo-5-carboxylate (5-methyl-2-oxo-1,3-dioxo len-4-yl)methyl
CAS:5-methyl-2-oxo-1,3-dioxo-4-[(4-[2-(trityl)phenyl]phenyl)methylimidazo]-5-carboxylate is a drug that belongs to the group of angiotensin II receptor antagonists. The main human metabolite is the product of N-dealkylation at the nitrogen atom of the imidazole ring. It has been shown to inhibit rat liver microsomes at concentrations of 2.5 and 5 μM. This compound is also found as an impurity in cilexetil and olmesartan, which are other drugs belonging to this class. Impurities can be detected by using metal hydroxides, amines and biphenyl as reagents, or with gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS), or high performance liquid chromatography/massFormula:C48H44N6O6Purezza:Min. 95%Colore e forma:SolidPeso molecolare:800.9 g/molClopidogrel EP Impurity B hydrochloride
CAS:Please enquire for more information about Clopidogrel EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C16H16ClNO2S•HClPurezza:Min. 95%Peso molecolare:358.28 g/molClidinium Bromide Related Compound C (Methyl 2-hydroxy-2,2-diphenylacetate) (International Restricted Item)
CAS:Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoiFormula:C15H14O3Colore e forma:Off-White PowderPeso molecolare:242.09429Ertapenem Ring Open Impurity
CAS:Ertapenem Ring Open Impurity is an impurity standard for research and development. It is a synthetic metabolite that is not present in the drug product. Ertapenem Ring Open Impurity is used as a standard to measure the purity of drugs, and it can be used as a reference material in pharmacopoeia and drug development. This impurity is also used in metabolism studies to determine the extent of conversion of ertapenem into its metabolites.Formula:C22H27N3O8SPurezza:Min. 95%Peso molecolare:493.53 g/mol2,3,4,5-Tetradehydro alfuzosin hydrochloride
CAS:Alfuzosin is a potent, selective, and long-acting α1A-adrenergic receptor antagonist. It is used to treat benign prostatic hyperplasia (BPH) in males. Alfuzosin is also used as an antihypertensive agent, for the treatment of pheochromocytoma, and for the treatment of benign prostatic hyperplasia in males. The hydrogenation of 2,3,4,5-tetradehydroalfuzosin to alfuzosin hydrochloride is performed by liquid hydrogenation or by hydrogenation on a palladium catalyst in a mixture of dimethylformamide and hexamethylphosphoramide. This process minimizes the formation of impurities such as 2,3,4-trimethoxy alfuzosin.Formula:C19H24ClN5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:421.88 g/molPseudomonic acid D sodium
CAS:Pseudomonic acid D sodium is a chemical compound that is found in coal tar. It has antimicrobial properties and can be used to inhibit the growth of bacteria and fungi. Pseudomonic acid D sodium has been shown to inhibit the growth of gram-positive bacterial strains, including Bacillus cereus, Clostridium perfringens, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus faecalis. It also inhibits the growth of yeast such as Candida albicans. Pseudomonic acid D sodium is soluble in water at low concentrations and insoluble in water at high concentrations. This chemical exhibits acidic properties with an acidic pH range from 2-4. Pseudomonic acid D sodium does not dissolve calcium carbonate or hydroxide solution due to its weakly acidic nature.Formula:C26H41NaO9Purezza:Min. 95%Peso molecolare:520.59 g/mol5''''-Methyl-apixaban
CAS:5''''-Methyl-apixaban is a drug product that is synthesized in the laboratory. It has been shown to be metabolized by cytochrome P450 enzymes, which are found in the liver, and eliminated by glucuronidation. This compound has been shown to have antiplatelet activity and is used for the prevention of stroke in patients with atrial fibrillation who cannot tolerate warfarin or those who need a higher dose of warfarin than can be achieved with standard doses. 5''''-Methyl-apixaban also inhibits platelet aggregation, leading to decreased blood clot formation. 5''''-Methyl-apixaban has been shown to have a number of metabolites including apixaban, which is formed through oxidation; apixanone, which is formed through hydrolysis; and apixanol, which is formed through conjugation with glucuronic acid. Apixanone has been shown to have more potent antiplatelet activityFormula:C26H27N5O4Purezza:Min. 95%Peso molecolare:473.5 g/molRotogotine EP impurity G
CAS:Rotogotine EP impurity G is an impurity of rotogotine EP. The compound is a synthetic material and has no known natural sources. Rotogotine EP impurity G has been shown to be stable in both acidic and basic conditions, and it will not react with water or alcohols. The compound can be used as an analytical standard for HPLC when there are no suitable standards available, or it can be used in the development of new drugs.
Formula:C22H25NOS2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:383.6 g/molClarithromycin EP impurity B
CAS:Clarithromycin EP impurity B is a natural impurity in clarithromycin. Clarithromycin EP impurity B is synthesized by the metabolism of clarithromycin, and its chromatographic retention time is 13.5 minutes. It has been shown to have anti-inflammatory and immuno-suppressive effects, which may be due to its inhibition of prostaglandin synthesis. Clarithromycin EP impurity B has been shown to inhibit the growth of bacteria that are resistant to penicillin, ampicillin, and erythromycin.Formula:C37H67NO13Purezza:90%NmrColore e forma:White PowderPeso molecolare:733.93 g/mol(5aS,10aS)-Tetrahydrodipyrrolo[1,2-a:1',2'-d]pyrazine-3,5,8,10(2H,5aH)-tetraone
CAS:The objective of this project is to design a microcontroller-based system that can monitor and diagnose the level of damage in a composite material. The system will consist of an array of sensors, actuators, and microcontrollers that are connected by a wireless network. The sensors will measure the levels of damage at each point within the composite material. The actuators will provide feedback to the sensors, adjusting their frequency and amplitude based on the level of damage detected. Microcontrollers will be responsible for analyzing data from the sensors and diagnosing any faults in the system. A miniaturized dry skin patch could be used as an alternative to traditional wet skin tests for monitoring skin health.Formula:C10H10N2O4Purezza:Min. 95%Peso molecolare:222.2 g/molTicagrelor acetate
CAS:Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor, preventing platelet aggregation. This chemical has been shown to reduce thrombus formation and improve survival rates after a heart attack. TICAGRELOR ACETATE: Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor,Formula:C25H30F2N6O5SPurezza:Min. 95%Peso molecolare:564.6 g/mol2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine
CAS:2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine is a cytosine analog that is used as an industrial chemical. It is prepared by the reaction of 5'-deoxycytidine with acetic anhydride in the presence of sodium bicarbonate, followed by a purification procedure. 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine reacts with toluene and trifluoromethanesulfonic acid to form 2',3'-di-O-acetyl 5'-deoxyfluorocytidine. This compound can be converted to 5'-deoxyfluorocytosine by heating in the presence of sodium tetrachloride. The yield for this process is high.
Formula:C13H16FN3O6Purezza:Min. 95%Peso molecolare:329.29 g/molN-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.Formula:C12H9F3N2O2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:270.21 g/molDapagliflozin Impurity 26
CAS:Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.Purezza:Min. 95%Dabigatran impurity E
CAS:Prodotto controllatoDabigatran impurity E is a potent kinase inhibitor that has shown promising results in the field of cancer research. It is an analog of a Chinese medicinal herb that has been traditionally used to treat various ailments, including cancer. Dabigatran impurity E has been shown to induce apoptosis in human cancer cells by inhibiting the activity of specific kinases involved in cell replication and survival. This compound also exhibits anticancer properties by inhibiting the growth and proliferation of tumor cells. Additionally, Dabigatran impurity E has been found in urine samples from cancer patients, suggesting its potential as a biomarker for cancer diagnosis and monitoring. Overall, this compound holds great promise as a novel therapeutic agent for the treatment of various types of cancers.
Formula:C20H22N4O3Purezza:Min. 95%Peso molecolare:366.4 g/molPantoprazole sulphide
CAS:Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.
Formula:C16H15F2N3O3SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:367.37 g/molSalbutamol EP Impurity F
CAS:Salbutamol EP Impurity F is a drug impurity that is an analytical standard and pharmacopoeia reference material. It is used in the manufacture of pharmaceuticals to ensure that the product meets quality standards. Salbutamol EP Impurity F has been shown to be a metabolite of salbutamol, which is produced as a result of oxidative metabolism by cytochrome P450 enzymes such as CYP3A4. The compound has also been observed in human urine and plasma.Formula:C26H40N2O5Purezza:Min. 95%Peso molecolare:460.61 g/molChlorthalidone impurity J
CAS:Chlorthalidone is a drug product that contains the impurity J. Chlorthalidone is an antihypertensive drug that belongs to the class of thiazides. It is used in the treatment of hypertension, congestive heart failure, and edema. Chlorthalidone is metabolized by the liver and eliminated through urine; it has been shown to be excreted unchanged in urine as well as in bile. The impurity J can be found in human urine, which may be due to metabolism by microorganisms or renal clearance.Formula:C14H10ClNO2Purezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:259.69 g/mol(6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol
CAS:(6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol is a synthetic compound with a molecular weight of 310.9 g/mol and CAS number 1369625-04-6. This product is an impurity standard for the HPLC analysis of the drug product in order to ensure the quality of the active pharmaceutical ingredient. The purity is > 99% and the content is between 0.1% and 5%. (6S)-6-[Ethyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol has been shown to be metabolized in vitro by rat liver microsomes to 3-(2'-hydroxyethoxy)benzaldehyde (0.3%), 2-(4'-hydroxybutFormula:C18H23NOSPurezza:Min. 95%Peso molecolare:301.4 g/molSalbutamol impurity L acetate salt
CAS:Salbutamol impurity L acetate salt is an analog of Salbutamol, which is a bronchodilator used to treat respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD). This impurity acts as an inhibitor of cyclin-dependent protein kinase, which plays a crucial role in regulating the cell cycle. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. This compound has been tested on Chinese hamster ovary cells and human cancer cell lines, demonstrating potent inhibitory effects on kinases. Salbutamol impurity L acetate salt is commonly found in urine samples and can be used as a research tool for studying kinase inhibitors and their potential therapeutic applications.Formula:C13H20ClNO3Purezza:Min. 95%Peso molecolare:273.75 g/molN-Desmethyl atracurium besylate
CAS:Please enquire for more information about N-Desmethyl atracurium besylate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C58H74N2O15SPurezza:Min. 95%Peso molecolare:1,071.3 g/mol5-(4-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde
CAS:Please enquire for more information about 5-(4-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C11H8FNOPurezza:Min. 95%Peso molecolare:189.19 g/molAmlodipine EP Impurity E maleate
CAS:Amlodipine EP Impurity E maleate is a high purity and analytical grade chemical. It is a metabolite of Amlodipine, which is used in the treatment of hypertension. This chemical has been shown to be a natural product that is produced by the human body. It also has been shown to have pharmacological properties, such as anti-inflammatory and vasodilatory effects. The impurity standard for this compound is available from Sigma-Aldrich.br>br>
Formula:C21H27ClN2O5•C4H4O4Purezza:Min. 95%Peso molecolare:538.98 g/mol(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester
CAS:(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester is a synthetic molecule that is used as an analytical standard for HPLC. It is also used in the research and development of drugs. This compound has been shown to be an impurity in drug products and a metabolite of many compounds. (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4]-b]indole carboxylic acid methyl ester has a molecular weight of 372.64 grams per mole and theFormula:C22H19ClN2O5Purezza:Min. 95%Peso molecolare:426.8 g/mol6-Pterinyl folic acid
CAS:6-Pterinyl folic acid is a chemical reagent that is used in the synthesis of pteridine derivatives. It is also used to prepare sulfates and esters of folic acid. 6-Pterinyl folic acid can be synthesized by reacting glutamic anhydride with trifluoroacetic acid and dimethylformamide. It reacts with sulfate ions to produce 6-pterinyl sulfate, which can then be hydrolyzed to release 6-pterinyl folic acid. The reagent can be used in the manufacture of fluoroquinolones, antibiotics that are used to treat a variety of bacterial infections including tuberculosis.Formula:C26H24N12O7Purezza:Min. 95%Peso molecolare:616.55 g/molRifaximin EP Impurity H
CAS:Rifaximin Impurity H is a research and development product that is available for custom synthesis. It is characterized by its high purity, analytical results, and natural origin. Rifaximin Impurity H has been shown to be a metabolite of the drug rifaximin and may be an impurity standard for HPLC analysis. This custom synthesis can also be used in pharmacopoeia standards and as a research tool for drug development.Formula:C43H51N3O12Purezza:Min. 95%Peso molecolare:801.88 g/mol(24R)-Calcipotriene
CAS:(24R)-Calcipotriene is a synthetic analog of calcitriol, the active form of vitamin D3. It is a proapoptotic agent that inhibits tumor growth by causing mitochondrial membrane potential collapse in cancer cells. (24R)-Calcipotriene has been shown to inhibit tumor growth in animals and human cells in vitro. This drug also potentiates the effects of other anticancer drugs such as doxorubicin and etoposide. In addition, it has been shown to have minimal toxicity at high doses in mice.
Formula:C27H40O3Purezza:Min. 95%Peso molecolare:412.6 g/molN-Ethyl Azilsartan Medoxomil
CAS:N-Ethyl azilsartan medoxomil is a drug product that is used as an analytical reference material and as a synthetic intermediate. It is also an impurity in the API azilsartan medoxomil, which is a drug product. N-Ethyl azilsartan medoxomil has CAS number 1417576-01-2 and Impurity Standard for N-Ethyl Azilsartan Medoxomil. This drug product can be used for research and development purposes and to produce other drugs. The impurities present in this compound are not specified but it does have HPLC standards of purity at 98% or greater.Formula:C32H28N4O8Purezza:Min. 95%Peso molecolare:596.60 g/molEmtricitabine impurity 17
CAS:Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C8H10FN3O4SPurezza:Min. 95%Peso molecolare:263.24 g/molIsopropyl 2-hydroxy-2-phenylacetate
CAS:Isopropyl 2-hydroxy-2-phenylacetate is an inorganic acid that is used as a solvent and as a reagent for sample preparation. It has been shown to be able to dissolve hydroxy methyl cellulose, which is a common component of membranes. In addition, it can be used as an electrospray ionization source and has been shown to have a phase transition temperature of -24 degrees Celsius. Isopropyl 2-hydroxy-2-phenylacetate has also been shown to inhibit the action of cholic acid on kinetics in high-performance liquid chromatography. This chemical compound also contains an ethyl group, which may be due to its derivation from acetone.Formula:C11H14O3Purezza:Min. 95%Peso molecolare:194.23 g/mol(3S,5S,6S)-Bupropion impurity
CAS:This is a drug product that has been developed for use in HPLC as a standard. It is a natural substance and is custom synthesized to meet the specific needs of research and development. It is an impurity standard that can be used for analytical purposes or pharmacopoeia, as well as metabolism studies. This compound is also available in high purity and at niche quantities to meet the needs of researchers who require it.Formula:C12H14ClNO3SPurezza:Min. 95%Peso molecolare:287.76 g/molPSI 7976
CAS:PSI 7976 is an analog of the nucleophilic attack drug, ribavirin. PSI 7976 inhibits the hepatitis C virus (HCV) replicon by inhibiting the function of the NS5B polymerase. In clinical studies, PSI 7976 has been shown to be active against HCV genotype 1 and 3. It has also been shown to inhibit replication of HIV-1 in vitro and to act synergistically with lamivudine against HIV-1 in human cells. PSI 7976 may be useful as a potential antiviral agent for treatment of other viral infections such as hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), or cytomegalovirus (CMV).Formula:C22H29FN3O9PPurezza:Min. 95%Peso molecolare:529.45 g/mol5,6-Dehydro-tigecycline
CAS:5,6-Dehydro-tigecycline is a synthetic antibiotic that is used for the treatment of multi-drug resistant bacterial infections. 5,6-Dehydro-tigecycline binds to the 30S ribosomal subunit and blocks protein synthesis by inhibiting peptidyl transferase activity. This drug has been shown to be effective in treating methicillin resistant Staphylococcus aureus (MRSA) infections. 5,6-Dehydro-tigecycline also inhibits the growth of Mycobacterium tuberculosis and Mycobacterium avium complex, although it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Metabolism studies have shown that 5,6-Dehydro-tigecycline undergoes oxidative metabolism via CYP450 enzymes to form reactive metabolites like N2-[(
Formula:C29H37N5O8Purezza:Min. 95%Peso molecolare:583.63 g/molMabuterol-d9
CAS:Please enquire for more information about Mabuterol-d9 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C13H18ClF3N2OPurezza:Min. 95%Peso molecolare:319.8 g/molMeropenem EP impurity A
CAS:Meropenem EP impurity A is a heterocyclic nitro compound that is used to treat various infectious diseases. Meropenem EP impurity A is an inhibitor of the toll-like receptor, which is a protein that recognizes and binds to bacterial lipopolysaccharide and mediates inflammation. This drug may be effective in treating colorectal carcinoma, autoimmune diseases, chronic bronchitis, cancer, and other inflammatory diseases. Meropenem EP impurity A also has anti-cancer properties due to its structural similarity with the chemotherapeutic agent 5-fluorouracil. Meropenem EP impurity A inhibits the synthesis of proteins by binding to the aminoacyl-tRNA synthetase enzyme and blocking the production of proteins vital for cell division.Formula:C17H27N3OS6Purezza:95%NmrColore e forma:PowderPeso molecolare:401.5 g/molEmpagliflozin ±-Anomer-d4
CAS:Empagliflozin is a drug product that is used in the treatment of type 2 diabetes. It is an investigational drug and its development is still ongoing. Empagliflozin has been shown to have high purity and analytical standards, as well as metabolite standards. It also has a natural form, which makes it a niche product for research and development purposes. The impurity standard for this product is CAS No. 1620758-33-9 and it can be synthesized with high purity, providing the synthetic form of this drug product.Formula:C23H23D4ClO7Purezza:Min. 95%Peso molecolare:454.93 g/molVildagliptin Related Compound 2
CAS:Vildagliptin Related Compound 2 is a synthetic compound that has been shown to be an inhibitor of DPP-4. It is a white solid that can be synthesized by condensation of vildagliptin with chloroacetyl chloride in the presence of an alkali. The compound was found to have impurities, including 1-(2-chlorophenyl)ethanol and 3-chlorobenzaldehyde.Formula:C17H25N3O2Purezza:Min. 95%Peso molecolare:303.4 g/molVildagliptin carboxylic acid methyl ester
CAS:Please enquire for more information about Vildagliptin carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C18H28N2O4Purezza:Min. 95%Peso molecolare:336.43 g/mol9-Cis,13-cis-retinol 15-acetate-d5
CAS:Please enquire for more information about 9-Cis,13-cis-retinol 15-acetate-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C22H32O2Purezza:Min. 95%Peso molecolare:333.5 g/molP,P′-[1-Hydroxy-3-(pentylamino)propylidene]bis[phosphonic acid]
CAS:Please enquire for more information about P,P′-[1-Hydroxy-3-(pentylamino)propylidene]bis[phosphonic acid] including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C8H21NO7P2Purezza:Min. 95%Peso molecolare:305.2 g/molGlycopyrrolate related B
CAS:Prodotto controllatoGlycopyrrolate related B is a drug product that belongs to the class of drugs for research and development. It is a natural metabolite of glycopyrrolate and is used as an analytical standard. The metabolite can also be used as a synthetic intermediate or impurity standard in pharmaceutical production. It has been shown that glycopyrrolate related B has niche applications in drug development and metabolism studies. Glycopyrrolate related B is not found in the pharmacopeia, but it can be synthesized by reacting the corresponding amine with pyrrole-2-carboxaldehyde.Formula:C18H26ClNO3Purezza:Min. 95%Peso molecolare:339.9 g/molα-Hydroxy olopatadine hydrochloride
CAS:Olopatadine is an antihistamine that is used to treat allergic rhinitis and seasonal allergic conjunctivitis. It is an α-hydroxy acid metabolite of the arylacetic acid group. This drug has been shown to inhibit the metabolism of olopatadine in humans, which may result in reduced potency for this drug. Olopatadine hydrochloride is used as a standard for quantitative analysis by high performance liquid chromatography (HPLC) and can be used as an impurity standard for preparing synthetic olopatadine. It is also used in drug development and research, such as evaluating its pharmacological properties and investigating its potential role in treating other ocular conditions such as dry eye syndrome.Formula:C21H23NO4•HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:389.9 g/molRuxolitinib Impurity 5
CAS:Ruxolitinib is a drug product that belongs to the class of small molecule drugs. It is an impurity standard for HPLC and other analytical techniques. Ruxolitinib Impurity 5 is a synthetic drug product, which has been custom synthesized for research and development purposes. This impurity standard is used as a pharmacopoeia in high-purity form.Formula:C23H32N6OSiPurezza:Min. 95%Peso molecolare:436.6 g/mol(1-Nitroethyl)benzene
CAS:(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.Formula:C8H9NO2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:151.16 g/mol3β-Hydroxy pravastatin lactone
CAS:3Beta-Hydroxy pravastatin lactone is a synthetic compound that is the primary metabolite of pravastatin. It has been shown to decrease cholesterol levels in the blood and to be an analytical standard for HPLC. 3Beta-Hydroxy pravastatin lactone has also been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.Formula:C23H34O6Purezza:Min. 95%Peso molecolare:406.50 g/molStigmastanol
CAS:Stigmastanol is a phytosterol isolated from Hypericum riparium, which is a Cameroonian medicinal plant.Formula:C29H52OPurezza:98.07%Colore e forma:SolidPeso molecolare:416.72OMDM-5
CAS:OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).Formula:C26H44N2O3Purezza:99.73%Colore e forma:SolidPeso molecolare:432.64Ref: TM-T12306
1mg93,00€5mg177,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.071,00€1mL*10mM (DMSO)210,00€Sumatriptan 3-hydroxy-2-oxo impurity
CAS:Please enquire for more information about Sumatriptan 3-hydroxy-2-oxo impurity including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C14H21N3O4SPurezza:Min. 95%Peso molecolare:327.4 g/molHylocerenin
CAS:Hylocerenin is a medicinal compound that shows promise as an anticancer agent. It is a protein kinase inhibitor, which means it can prevent the growth and spread of cancer cells. Hylocerenin is derived from Chinese herbal medicine and is an analog of a natural compound found in urine. Studies have shown that hylocerenin induces apoptosis or programmed cell death in tumor cells, making it a potential treatment for cancer. This compound has been tested on human cancer cell lines and has demonstrated its effectiveness as a kinase inhibitor, making it a promising candidate for future cancer treatments.Formula:C30H34N2O17Purezza:Min. 95%Peso molecolare:694.6 g/molAcarbose EP Impurity F
CAS:Acarbose EP Impurity F is an analytical impurity that is found in Acarbose EP, a drug product. Acarbose EP Impurity F is a synthetic compound and is not present in any natural products. The CAS number for this impurity is 83116-09-0. Acarbose EP Impurity F has been shown to be pharmacologically active in animal studies, but the specific activity of this impurity has not been determined. Acarbose EP Impurity F is used as an impurity standard in HPLC analysis of Acarbose EP and as a custom synthesis. Acarbose EP Impurity F may also be used as a research and development phase, niche product or as a drug development research compound.Formula:C31H53NO23Purezza:Min. 95%Peso molecolare:807.75 g/mol2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole
CAS:2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole is a drug product that is used in research and development. It is an analytical standard for the impurity 2-(Methoxymethyl)-5-phenylthio-1H-benzimidazole, which has a natural origin. The impurity standard can be used to assess the purity of the API by HPLC. This drug product is also used as a Metabolism studies and Natural standards. These standards are used to study the metabolism of drugs, which can lead to new insights into their therapeutic action and toxicity. 2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole can be synthesized in custom synthesis or synthetic methods. It has been shown to have niche uses in drug development, research and development, and analytical chemistry.Formula:C15H14N2OSPurezza:Min. 95%Peso molecolare:270.4 g/molDutasteride EP impurity D
CAS:Please enquire for more information about Dutasteride EP impurity D including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C27H28F6N2O2Purezza:Min. 95%Peso molecolare:526.51 g/molAcarbose EP Impurity H
CAS:Acarbose EP Impurity H is an impurity of acarbose, a drug product used in the treatment of type II diabetes. Acarbose is a natural product and its synthesis starts from a chemical called alpha-D-glucopyranosyl-3-O-[2,4,6-trichloro-3-(trifluoromethyl)phenyl]pyridine. Acarbose is metabolized by the liver to form Acarbose EP Impurity H. The metabolism studies of this impurity have shown that it has niche pharmacological properties. Acarbose EP Impurity H can be used as an analytical or API impurity for HPLC standard or as a synthetic intermediate for pharmaceutical research and development.Formula:C25H43NO17Purezza:Min. 95%Peso molecolare:629.61 g/molAcarbose EP Impurity G
CAS:Acarbose EP Impurity G is a pharmaceutical grade impurity that is used as a reference standard for HPLC and LC-MS analysis. Acarbose EP Impurity G is a metabolite of acarbose and can be found in human plasma. It has been shown that Acarbose EP Impurity G induces the metabolism of glucose, which may be due to its ability to inhibit the activity of alpha-glucosidase. Acarbose EP Impurity G also inhibits the activity of pancreatic beta-cells, leading to impaired insulin secretion.Formula:C31H53NO23Purezza:Min. 95%Peso molecolare:807.75 g/molDesfluoro ciprofloxacin hydrochloride
CAS:Fluoroquinolones are a class of antibiotics that are used to treat bacterial infections. Desfluoro ciprofloxacin hydrochloride is a fluorinated derivative of ciprofloxacin and is an ultra-fast synthetic compound. It has been shown to be more potent than the parent molecule. This drug is considered to be impure because it contains other chemical compounds, such as isomers and back-pressure products. The particle size distribution of desfluoro ciprofloxacin hydrochloride is usually very broad with diameters ranging from 5 nm to 1 micron. It can be separated by particle size in a phase liquid chromatography column because the particles have different hydrodynamic diameters. Desfluoro ciprofloxacin hydrochloride can also be separated by phase chromatography on an oligosaccharide column, which produces more efficient separation than traditional high-performance liquid chromatography (HPLC).Formula:C17H19N3O3·HClPurezza:Min. 95%Colore e forma:Off-White PowderPeso molecolare:349.81 g/mol14-Hydroxy clarithromycin
CAS:14-Hydroxy clarithromycin is an analog of clarithromycin that has been shown to have anticancer properties. It is excreted in urine and has been found to inhibit several kinases, including cyclin-dependent kinases and protein kinase C. This drug induces apoptosis in cancer cells and inhibits tumor growth in Chinese hamsters. 14-Hydroxy clarithromycin has also been studied as a potential inhibitor of the human kinase, which may have implications for the development of new cancer therapies. Overall, this drug shows promise as an effective anticancer agent with potential for further research and development.Formula:C38H69NO13Purezza:Min. 95%Peso molecolare:748 g/molSitagliptin impurity E
CAS:Sitagliptin impurity E is an inhibitor of dipeptidyl peptidase-4 (DPP-IV) that is used as a hypoglycemic agent. Sitagliptin impurity E has been shown to increase the glucose-lowering effect in diabetic patients with type 2 diabetes mellitus. It is also effective in reducing postprandial glucose and insulin levels. Sitagliptin impurity E has been shown to increase the concentration of insulin in plasma for up to 24 hours after administration, which suggests that it may be useful for the treatment of metabolic disorders such as obesity and type 2 diabetes mellitus.
Formula:C16H15F6N5OPurezza:Min. 95%Peso molecolare:407.31 g/molAnhydro abiraterone
CAS:Prodotto controllatoAnhydro abiraterone is a metabolite of abiraterone, which is a drug used in the treatment of prostate cancer. It has been shown to be active in the inhibition of human cytochrome P450 and has been found to be an impurity in commercial preparations of abiraterone. Anhydro abiraterone is almost insoluble in water, but can be purified by recrystallization from ethanol.Formula:C24H29NPurezza:Min. 95%Colore e forma:PowderPeso molecolare:331.49 g/mol6-Oxo mometasone furoatemometasone furoate impurity F
CAS:6-Oxo mometasone furoatemometasone furoate impurity F is a drug product that is an impurity standard for the synthesis of 6-oxo mometasone furoatemometasone furoate. This impurity has been shown to have a metabolite profile similar to that of 6-oxo mometasone furoatemometasone furoate, but with a different retention time in HPLC analysis. It has also been shown to be present in natural products and to inhibit metabolism studies. This impurity should be used as an analytical standard for HPLC analysis of 6-oxo mometasone furoatemometasone furoate.Formula:C27H28Cl2O7Purezza:Min. 95%Peso molecolare:535.4 g/molN-Hydroxy sertraline
CAS:N-Hydroxy sertraline is a metabolite of the antidepressant drug, sertraline. It is formed by the action of cytochrome P450 enzymes in the liver. N-Hydroxy sertraline is not active as an antidepressant, but it may have some activity against bacterial infections. There are no pharmacopoeia standards for this compound.Formula:C17H17Cl2NOPurezza:Min. 95%Peso molecolare:322.20 g/molDesogestrel Related Compound A
CAS:Desogestrel Related Compound A is a synthetic impurity standard. It is the metabolite of desogestrel, which belongs to the drug class progestins and is used for contraception. Desogestrel Related Compound A is used as a research and development or impurity standard for pharmacopoeia-grade drugs or custom synthesis with high purity. The CAS number for this product is 201360-82-9.Formula:C22H30OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:310.47 g/mol1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene
CAS:1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene is a synthetic silyl ether of calcipotriene. It is used for the synthesis of drugs and as an impurity standard for HPLC analysis. 1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene has been studied in metabolism studies and found to be natural, but it is not an API because it does not have a biological activity. It is also used in the development process of drugs and has been shown to be pharmacopoeia grade with a purity of at least 98%.
Formula:C39H68O3Si2Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:641.13 g/mol7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole
CAS:7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.
Formula:C18H18N4Purezza:Min. 95%Peso molecolare:290.36 g/mol2,2',4,4',6,6'-Hexachlorobiphenyl
CAS:Prodotto controllato2,2',4,4',6,6'-Hexachlorobiphenyl (PCB-136) is a potent anticancer agent that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor by blocking the activity of specific kinases involved in tumor growth and progression. PCB-136 has been studied extensively in human and Chinese hamster ovary cells and has been found to be highly effective against various types of cancer. This medicinal analog also exhibits inhibitory effects on the protein kinases that regulate cell division and proliferation, making it a promising candidate for cancer therapy. In addition, PCB-136 shows potential for use as a urinary biomarker for exposure to environmental pollutants due to its persistence in the environment and ability to accumulate in body tissues.
Formula:C12H4Cl6Purezza:Min. 95%Peso molecolare:360.9 g/molBromfenac Related Compound A
CAS:Bromfenac Related Compound A is a chemical impurity, which is often encountered during the synthesis and formulation of bromfenac, a non-steroidal anti-inflammatory drug (NSAID). This compound arises as a byproduct in the chemical synthetic pathway utilized in the production of bromfenac, necessitating stringent analytical methods to ensure product purity and compliance with pharmaceutical standards.The mode of action for Bromfenac Related Compound A itself is not typically characterized, as it is primarily the parent compound, bromfenac, that is pharmacologically active. Bromfenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2) that mediate inflammatory processes. However, the related compound is investigated to understand the synthesis intricacies and to refine processes that limit its formation.Understanding and controlling the levels of Bromfenac Related Compound A is crucial in pharmaceutical applications, as the presence of impurities can affect the efficacy, safety, and overall quality of the drug product. Analytical chemists and pharmaceutical scientists study this compound extensively using chromatographic and spectroscopic techniques to ensure drug safety and compliance with regulatory guidelines.Formula:C15H10BrNO4Peso molecolare:348.15 g/molPidotimod diketopiperazine-6-propanoic acid
CAS:Pidotimod is an impurity in the drug product, which is a synthetic diketopiperazine-6-propanoic acid. Pidotimod is an impurity standard that is used in the development of drugs and as a pharmacopoeia. It has been shown to be metabolized by human liver microsomes and human erythrocytes.Formula:C9H12N2O4SPurezza:Min. 95%Peso molecolare:244.27 g/mol1-(6-Chloro-9H-carbazol-2-yl)ethanone
CAS:1-(6-Chloro-9H-carbazol-2-yl)ethanone is a chemical substance that belongs to the class of synthetic drugs. It is used as a pharmaceutical intermediate in the production of other chemical substances, including antibiotics and antihypertensives. 1-(6-Chloro-9H-carbazol-2-yl)ethanone has been shown to be metabolized by cytochrome P450 enzymes and by glucuronidases or esterases. This product can also be used as an impurity standard for HPLC analyses of fluoroquinolones.
Formula:C14H10ClNOPurezza:Min. 95%Peso molecolare:243.69 g/molQuetiapine ep impurity P
CAS:Quetiapine ep impurity P is a metabolite of quetiapine. It is a synthetic compound with pharmacopoeia and analytical standards available. Quetiapine ep impurity P is used in research and development to study the metabolism of quetiapine, but it also has niche uses in drug product development. Quetiapine ep impurity P can be synthesized by high-purity custom synthesis or natural methods, such as from plants.Formula:C19H21N3SPurezza:Min. 95%Peso molecolare:323.5 g/mol
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